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ES2033578A1 - Di:methyl-amino-ethyl-methyl-amino-sulphonyl-methyl-indole prepn. - Google Patents

Di:methyl-amino-ethyl-methyl-amino-sulphonyl-methyl-indole prepn.

Info

Publication number
ES2033578A1
ES2033578A1 ES919101360A ES9101360A ES2033578A1 ES 2033578 A1 ES2033578 A1 ES 2033578A1 ES 919101360 A ES919101360 A ES 919101360A ES 9101360 A ES9101360 A ES 9101360A ES 2033578 A1 ES2033578 A1 ES 2033578A1
Authority
ES
Spain
Prior art keywords
methyl
amino
ethyl
prepn
sulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES919101360A
Other languages
Spanish (es)
Other versions
ES2033578B1 (en
Inventor
Barjoan Pere Dalmases
Olondriz Francisco Marquillas
Rovira Anna Bosch
Ges Jose Maria Caldero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inke SA
Original Assignee
Inke SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inke SA filed Critical Inke SA
Priority to ES09101360A priority Critical patent/ES2033578B1/en
Priority to NO930443A priority patent/NO300589B1/en
Priority to PT10119893A priority patent/PT101198B/en
Priority to CZ93197A priority patent/CZ283683B6/en
Priority to AT27593A priority patent/AT399870B/en
Publication of ES2033578A1 publication Critical patent/ES2033578A1/en
Application granted granted Critical
Publication of ES2033578B1 publication Critical patent/ES2033578B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Indole Compounds (AREA)

Abstract

Prodn. of 3-(2-(dimethylamino) ethyl) -N-methyl -IH-indol-5-methane sulphonamide (I) comprises decarboxylation of 2-carboxy-3-(2-dimethyl amino) ethyl)-N-methyl -IH-indol-5-methane sulphonamide (II) in the presence of a solvent and a catalyst under inert atmos. at 190-250 deg.C.
ES09101360A 1991-06-06 1991-06-06 PROCEDURE FOR OBTAINING 3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE. Expired - Fee Related ES2033578B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES09101360A ES2033578B1 (en) 1991-06-06 1991-06-06 PROCEDURE FOR OBTAINING 3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE.
NO930443A NO300589B1 (en) 1991-06-06 1993-02-09 Process for Preparation of 3- [2- (Dimethylamino) -ethyl] -N-methyl-1H-indole-5-methanesulfonamide
PT10119893A PT101198B (en) 1991-06-06 1993-02-12 PROCESS FOR OBTAINING 3- {2- (DIMETHYLAMINO) ETHYL} -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE
CZ93197A CZ283683B6 (en) 1991-06-06 1993-02-15 Process for preparing 3-/2-(dimethylamino)ethyl/-n-methyl -1h - indole-5-methane sulfonamide
AT27593A AT399870B (en) 1991-06-06 1993-02-15 Process for the preparation of 3-(2-(dimethylamino)ethyl)- N-methyl-1H-indole-5-methanesulphonamide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09101360A ES2033578B1 (en) 1991-06-06 1991-06-06 PROCEDURE FOR OBTAINING 3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE.
CZ93197A CZ283683B6 (en) 1991-06-06 1993-02-15 Process for preparing 3-/2-(dimethylamino)ethyl/-n-methyl -1h - indole-5-methane sulfonamide

Publications (2)

Publication Number Publication Date
ES2033578A1 true ES2033578A1 (en) 1993-03-16
ES2033578B1 ES2033578B1 (en) 1995-01-16

Family

ID=25746855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09101360A Expired - Fee Related ES2033578B1 (en) 1991-06-06 1991-06-06 PROCEDURE FOR OBTAINING 3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE.

Country Status (2)

Country Link
CZ (1) CZ283683B6 (en)
ES (1) ES2033578B1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2056025A1 (en) * 1992-10-08 1994-09-16 Almirall Lab New indole derivatives
WO2004014877A1 (en) * 2002-08-07 2004-02-19 Vita Cientifica, S.L. Process for preparing rizatriptan
WO2004099140A1 (en) * 2003-05-08 2004-11-18 Hetero Drugs Limited Novel crystalline forms of sumatriptan succinate

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2084560B1 (en) * 1994-03-09 1997-01-16 Almirall Lab EL INDOL DERIVATIVES PREPARATION PROCEDURE.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2081717A (en) * 1980-08-12 1982-02-24 Glaxo Group Ltd Hereocyclic compounds
EP0145459A2 (en) * 1983-12-06 1985-06-19 Glaxo Group Limited Process for the production of chemical compounds
EP0147107A1 (en) * 1983-12-06 1985-07-03 Glaxo Group Limited Indole derivates

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2081717A (en) * 1980-08-12 1982-02-24 Glaxo Group Ltd Hereocyclic compounds
EP0145459A2 (en) * 1983-12-06 1985-06-19 Glaxo Group Limited Process for the production of chemical compounds
EP0147107A1 (en) * 1983-12-06 1985-07-03 Glaxo Group Limited Indole derivates

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2056025A1 (en) * 1992-10-08 1994-09-16 Almirall Lab New indole derivatives
WO2004014877A1 (en) * 2002-08-07 2004-02-19 Vita Cientifica, S.L. Process for preparing rizatriptan
ES2204303A1 (en) * 2002-08-07 2004-04-16 Laboratorios Vita, S.A. Process for preparing rizatriptan
US7279581B2 (en) 2002-08-07 2007-10-09 Inke, S.A. Process for preparing a pharmaceutically active compound
WO2004099140A1 (en) * 2003-05-08 2004-11-18 Hetero Drugs Limited Novel crystalline forms of sumatriptan succinate

Also Published As

Publication number Publication date
ES2033578B1 (en) 1995-01-16
CZ19793A3 (en) 1994-08-17
CZ283683B6 (en) 1998-06-17

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Legal Events

Date Code Title Description
GC2A Exploitation certificate registered application with search report

Effective date: 19970415

FD2A Announcement of lapse in spain

Effective date: 20111201