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ES2028987T3 - Un procedimiento para la preparacion de una composicion farmaceutica dispuesta para su disolucion en agua, de un antibiotico beta-lactamico anfotero. - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica dispuesta para su disolucion en agua, de un antibiotico beta-lactamico anfotero.

Info

Publication number
ES2028987T3
ES2028987T3 ES198888201049T ES88201049T ES2028987T3 ES 2028987 T3 ES2028987 T3 ES 2028987T3 ES 198888201049 T ES198888201049 T ES 198888201049T ES 88201049 T ES88201049 T ES 88201049T ES 2028987 T3 ES2028987 T3 ES 2028987T3
Authority
ES
Spain
Prior art keywords
water
pharmaceutical composition
beta
anphotero
lactamic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888201049T
Other languages
English (en)
Inventor
Hong Sheng Tan
Hendrik Van Sinderen
Edoaldus Vork
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of ES2028987T3 publication Critical patent/ES2028987T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION PROPORCIONA UNA COMPOSICION FARMACEUTICA SECA DE UN ANTIBIOTICO DE BETA-LACTAMA ANFOTERO, LISTO PARA LA DISOLUCION RAPIDA EN AGUA, QUE COMPRENDE UNA CANTIDAD DE 0,1 A 50% EN PESO DE UNA SAL ALCALINA DE UN CARBONATO DE AMINOACIDO. LA COMPOSICION PREFERIDA ES UNA EN LA QUE EL CARBONATO DE GLICINA SODICA ES EL CARBONATO DE AMINOACIDO Y LA AMOXICILINA ES EL ANTIBIOTIFO DE BETA-LACTAMA. ESTAS COMPOSICIONES SON PARTICULARMENTE ADECUADAS PARA SU ADMINISTRACION EN EL AGUA DE BEBER A LOS ANIMALES DE GRANJA.
ES198888201049T 1987-05-27 1988-05-25 Un procedimiento para la preparacion de una composicion farmaceutica dispuesta para su disolucion en agua, de un antibiotico beta-lactamico anfotero. Expired - Lifetime ES2028987T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87201002 1987-05-27

Publications (1)

Publication Number Publication Date
ES2028987T3 true ES2028987T3 (es) 1992-07-16

Family

ID=8197622

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888201049T Expired - Lifetime ES2028987T3 (es) 1987-05-27 1988-05-25 Un procedimiento para la preparacion de una composicion farmaceutica dispuesta para su disolucion en agua, de un antibiotico beta-lactamico anfotero.

Country Status (10)

Country Link
EP (1) EP0293975B1 (es)
JP (1) JPH02500591A (es)
KR (1) KR890701104A (es)
AU (1) AU607784B2 (es)
DE (1) DE3863847D1 (es)
DK (1) DK669588D0 (es)
ES (1) ES2028987T3 (es)
FI (1) FI90311C (es)
GR (1) GR3002972T3 (es)
WO (1) WO1988009173A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814337A (en) * 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
GB9405856D0 (en) * 1994-03-24 1994-05-11 Smithkline Beecham Plc Pharmaceutical formulation
SI20411A (sl) * 1999-12-22 2001-06-30 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Vodotopni praški za peroralno raztopino in njihova uporaba
GB2404336A (en) * 2003-07-30 2005-02-02 Cipla Ltd Stabilisation of therapeutic agents using a carbonate salt of an amino acid, preferably in the presence of a saccharide, & pharmaceutical compositions thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1113492A (en) * 1964-05-20 1968-05-15 Bristol Myers Co Chewable tablets comprising a penicillin antibiotic
FR2096949B1 (es) * 1970-07-20 1973-08-10 Peirano Berthe
US3940483A (en) * 1971-02-05 1976-02-24 E. R. Squibb & Sons, Inc. Antibiotic compositions and method
GB1437788A (en) * 1973-01-31 1976-06-03 Gist Brocades Nv Therapeutic compositions
GB1504767A (en) * 1976-08-23 1978-03-22 Beecham Group Ltd Antibiotic compositions
JPS563851A (en) * 1979-06-22 1981-01-16 Matsushita Electric Works Ltd Fireplace in floor
ES8502863A1 (es) * 1982-09-10 1985-02-01 Glaxo Group Ltd Un procedimiento para la produccion de un recipiente hermeticamente cerrado que contiene al menos un antibiotico de beta-lactama.
ATE68695T1 (de) * 1984-12-14 1991-11-15 Gergely Gerhard Teilchen aus einer hydrophoben oder schwerloeslichen substanz und verfahren zu ihrer hydrophilisierung.

Also Published As

Publication number Publication date
EP0293975A1 (en) 1988-12-07
EP0293975B1 (en) 1991-07-24
DK669588A (da) 1988-11-30
AU607784B2 (en) 1991-03-14
GR3002972T3 (en) 1993-01-25
FI890326A0 (fi) 1989-01-23
DK669588D0 (da) 1988-11-30
FI90311B (fi) 1993-10-15
FI90311C (fi) 1994-01-25
KR890701104A (ko) 1989-12-19
AU1932088A (en) 1988-12-21
DE3863847D1 (de) 1991-08-29
FI890326L (fi) 1989-01-23
JPH02500591A (ja) 1990-03-01
WO1988009173A1 (en) 1988-12-01

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