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ES2096014T3 - Compuestos esteroides activos sobre el sistema cardiovascular. - Google Patents

Compuestos esteroides activos sobre el sistema cardiovascular.

Info

Publication number
ES2096014T3
ES2096014T3 ES92200375T ES92200375T ES2096014T3 ES 2096014 T3 ES2096014 T3 ES 2096014T3 ES 92200375 T ES92200375 T ES 92200375T ES 92200375 T ES92200375 T ES 92200375T ES 2096014 T3 ES2096014 T3 ES 2096014T3
Authority
ES
Spain
Prior art keywords
cardiovascular system
steroid compounds
active steroid
sub
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92200375T
Other languages
English (en)
Inventor
Giorgio Bertolini
Cesare Casagrande
Stefania Montanari
Gabriele Norcini
Francesco Santangelo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Application granted granted Critical
Publication of ES2096014T3 publication Critical patent/ES2096014T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/001Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class spiro-linked
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN LOS COMPUESTOS ESTEROIDES ACTIVOS EN EL SISTEMA CARDIOVASCULAR , DE LA FORMULA DONDE X, N, R, R SUB 1 Y R SUB 2 TIENEN LOS SIGNIFICADOS MENCIONADOS EN LA DESCRIPCION ANTERIOR.
ES92200375T 1991-02-14 1992-02-11 Compuestos esteroides activos sobre el sistema cardiovascular. Expired - Lifetime ES2096014T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910380A IT1250410B (it) 1991-02-14 1991-02-14 Composti steroidei attivi sul sistema cardiovascolare

Publications (1)

Publication Number Publication Date
ES2096014T3 true ES2096014T3 (es) 1997-03-01

Family

ID=11358571

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92200375T Expired - Lifetime ES2096014T3 (es) 1991-02-14 1992-02-11 Compuestos esteroides activos sobre el sistema cardiovascular.

Country Status (7)

Country Link
US (1) US5426179A (es)
EP (1) EP0499327B1 (es)
JP (1) JPH0565293A (es)
AT (1) ATE145213T1 (es)
DE (1) DE69215125T2 (es)
ES (1) ES2096014T3 (es)
IT (1) IT1250410B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4232681C2 (de) * 1992-09-29 1994-11-24 Sigma Tau Ind Farmaceuti 17-Phenyl- und 17-Furyl-14beta,5alpha-androstan- und androsten- Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung
US5597806A (en) * 1995-05-09 1997-01-28 Merck & Co., Inc. Antifungal agents
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
DK3664470T3 (da) 2018-12-05 2021-04-19 Sonova Ag Fremskaffelse af feedback om lydstyrken af egen stemme for en bruger af et høreapparat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968132A (en) * 1974-12-23 1976-07-06 Schering Corporation (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones, methods for their manufacture and intermediates useful therein
DE2546779A1 (de) * 1975-10-18 1977-04-28 Boehringer Mannheim Gmbh Neue 20.22-dihydro-cardenolid- glykoside
FR2451923A1 (fr) * 1979-03-22 1980-10-17 Roussel Uclaf Nouveaux derives steroides 7-alkyles, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE69215125D1 (de) 1996-12-19
ITMI910380A0 (it) 1991-02-14
ITMI910380A1 (it) 1992-08-14
EP0499327B1 (en) 1996-11-13
EP0499327A1 (en) 1992-08-19
DE69215125T2 (de) 1997-06-12
US5426179A (en) 1995-06-20
JPH0565293A (ja) 1993-03-19
ATE145213T1 (de) 1996-11-15
IT1250410B (it) 1995-04-07

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