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ES2093579T3 - Monoclorhidrato de terazosina y procedimiento y productos intermediarios para la preparacion. - Google Patents

Monoclorhidrato de terazosina y procedimiento y productos intermediarios para la preparacion.

Info

Publication number
ES2093579T3
ES2093579T3 ES95103186T ES95103186T ES2093579T3 ES 2093579 T3 ES2093579 T3 ES 2093579T3 ES 95103186 T ES95103186 T ES 95103186T ES 95103186 T ES95103186 T ES 95103186T ES 2093579 T3 ES2093579 T3 ES 2093579T3
Authority
ES
Spain
Prior art keywords
preparation
monoclorhidrato
terazosine
procedure
intermediary products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95103186T
Other languages
English (en)
Other versions
ES2093579T1 (es
Inventor
James A Morley
John F Bauer
Ramesh R Patel
Stephen G Spanton
Rodger F Henry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22931058&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2093579(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES2093579T1 publication Critical patent/ES2093579T1/es
Application granted granted Critical
Publication of ES2093579T3 publication Critical patent/ES2093579T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SUMINISTRA UN POLIMORFO CRISTALINO DE MONOHIDROCLORURO DE TERAZOSIN DESIGNADA FORMA III Y METODOS PARA SU PREPARACION. TAMBIEN SE PRESENTA UN METANOLATO DE MONOHIDROCLORURO DE TERAZOSIN Y UN PROCESO PARA SU PRODUCCION ASI COMO PROCESOS PARA SU CONVERSION EN OTRAS FORMAS CRISTALINAS DE MONOHIDROCLORURO DE TERAZOSIN.
ES95103186T 1994-05-20 1995-03-06 Monoclorhidrato de terazosina y procedimiento y productos intermediarios para la preparacion. Expired - Lifetime ES2093579T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/246,526 US5412095A (en) 1993-04-29 1994-05-20 Terazosin monohydrochloride and processes and intermediate for its production

Publications (2)

Publication Number Publication Date
ES2093579T1 ES2093579T1 (es) 1997-01-01
ES2093579T3 true ES2093579T3 (es) 1999-11-01

Family

ID=22931058

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95103186T Expired - Lifetime ES2093579T3 (es) 1994-05-20 1995-03-06 Monoclorhidrato de terazosina y procedimiento y productos intermediarios para la preparacion.

Country Status (9)

Country Link
US (1) US5412095A (es)
EP (1) EP0683167B1 (es)
JP (1) JP2755918B2 (es)
AT (1) ATE182592T1 (es)
CA (1) CA2143974C (es)
DE (2) DE69510999T2 (es)
DK (1) DK0683167T3 (es)
ES (1) ES2093579T3 (es)
GR (2) GR960300046T1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587377A (en) * 1995-10-24 1996-12-24 Invamed, Inc. Terazosin crystalline polymorph and pharmaceutical compositions thereof
DE19546573A1 (de) * 1995-12-13 1997-06-19 Uetikon Chemie Gmbh Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung
US5952003A (en) * 1996-08-01 1999-09-14 Novartis Corporation Terazosin capsules
IT1286789B1 (it) * 1996-11-29 1998-07-17 Alfa Chem Ital Processo per la produzione della forma i del terazosin monocloridato anidro
IT1286790B1 (it) * 1996-11-29 1998-07-17 Alfa Chem Ital Processo per la produzione della forma i del terazosin monocloridrato anidro
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
ATE353892T1 (de) * 1996-12-20 2007-03-15 Heumann Pharma Gmbh & Co Neue polymorphe form von doxazosinmesylat (form iii)
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
US6248888B1 (en) 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
US6200573B1 (en) 1999-12-03 2001-03-13 Starcor Pharmaceuticals, Inc. Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia
US20030068829A1 (en) * 2001-06-25 2003-04-10 Symyx Technologies, Inc. High throughput crystallographic screening of materials
TWI353979B (en) * 2002-04-10 2011-12-11 Nippon Zoki Pharmaceutical Co Novel crystal form of 5-hydroxy-1-methylhydantoin
WO2008021891A2 (en) * 2006-08-08 2008-02-21 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
ATE72244T1 (de) * 1986-03-21 1992-02-15 Heumann Pharma Gmbh & Co Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
US5212176A (en) * 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
JP2652272B2 (ja) * 1990-12-31 1997-09-10 住化ファインケム株式会社 1−(4−アミノ−6,7−ジメトキシ−2−キナゾリニル)−4−(2−テトラヒドロフロイル)ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
US5294615A (en) * 1993-04-29 1994-03-15 Abbott Laboratories Terazosin polymorph and pharmaceutical composition

Also Published As

Publication number Publication date
JP2755918B2 (ja) 1998-05-25
DE69510999D1 (de) 1999-09-02
EP0683167A1 (en) 1995-11-22
DE69510999T2 (de) 2000-02-17
CA2143974C (en) 1997-06-03
GR960300046T1 (en) 1996-08-31
DE683167T1 (de) 1996-11-07
HK1012629A1 (en) 1999-08-06
ES2093579T1 (es) 1997-01-01
DK0683167T3 (da) 2000-02-07
CA2143974A1 (en) 1995-11-21
GR3031248T3 (en) 1999-12-31
JPH0848685A (ja) 1996-02-20
US5412095A (en) 1995-05-02
ATE182592T1 (de) 1999-08-15
EP0683167B1 (en) 1999-07-28

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