ES2078319T3 - Composiciones que contienen inhibidores de aldosa reductasa para el tratamiento de ulceras. - Google Patents
Composiciones que contienen inhibidores de aldosa reductasa para el tratamiento de ulceras.Info
- Publication number
- ES2078319T3 ES2078319T3 ES90312053T ES90312053T ES2078319T3 ES 2078319 T3 ES2078319 T3 ES 2078319T3 ES 90312053 T ES90312053 T ES 90312053T ES 90312053 T ES90312053 T ES 90312053T ES 2078319 T3 ES2078319 T3 ES 2078319T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- ulcers
- aldosa
- compositions containing
- reductase inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000025865 Ulcer Diseases 0.000 title abstract 2
- 231100000397 ulcer Toxicity 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002500 effect on skin Effects 0.000 abstract 2
- 102000016912 Aldehyde Reductase Human genes 0.000 abstract 1
- 108010053754 Aldehyde reductase Proteins 0.000 abstract 1
- 208000001034 Frostbite Diseases 0.000 abstract 1
- 208000004210 Pressure Ulcer Diseases 0.000 abstract 1
- 206010039710 Scleroderma Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 229940053195 antiepileptics hydantoin derivative Drugs 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
UNA PREPARACION TERAPEUTICA PARA EL TRATAMIENTO DE LAS ULCERAS DE LA PIEL, LABIALES, INTRAORALES Y DEL APARATO DIGESTIVO, DE LAS HERIDAS POR AGENTES CORROSIVOS, DE LAS ULCERAS POR DECUBITO, QUEMADURAS, ULCERAS POR CONGELACION Y ESCLERODERMA, QUE CONTIENE COMO INGREDIENTE PRINCIPAL UN COMPUESTO QUE TIENE UNA ACTIVIDAD INHIBITORIA DE LA ALDOSA REDUCTASA, Y EL CUAL PUEDE ACELERAR EL METABOLISMO DE LA DERMIS. LOS COMPUESTOS MAS UTILIZADOS SON DERIVADOS DE LA HIDANTOINA OPTICAMENTE ACTIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005773A JPH03215435A (ja) | 1990-01-12 | 1990-01-12 | アルドース還元酵素阻害剤を主成分とする潰瘍治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2078319T3 true ES2078319T3 (es) | 1995-12-16 |
Family
ID=11620439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90312053T Expired - Lifetime ES2078319T3 (es) | 1990-01-12 | 1990-11-02 | Composiciones que contienen inhibidores de aldosa reductasa para el tratamiento de ulceras. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5155125A (es) |
| EP (1) | EP0437025B1 (es) |
| JP (1) | JPH03215435A (es) |
| AT (1) | ATE127344T1 (es) |
| DE (1) | DE69022206T2 (es) |
| DK (1) | DK0437025T3 (es) |
| ES (1) | ES2078319T3 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0661293A3 (en) * | 1993-12-29 | 1999-05-19 | Sanwa Kagaku Kenkyusho Co., Ltd. | Protein having cell growth-stimulating and macrophage chemotactic actions, preparative method therefor and use thereof |
| DE69519219T2 (de) * | 1994-12-28 | 2001-02-22 | Sanwa Kagaku Kenkyusho, Co. | Verwendung von (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazoline]-2-carboxamid zur Behandlung von Keratopathie |
| EP0909558A3 (en) * | 1997-08-29 | 1999-10-27 | Santen Pharmaceutical Co., Ltd. | Chroman derivative containing ophthalmic solution |
| WO2006022450A1 (ja) * | 2004-08-26 | 2006-03-02 | Santen Pharmaceutical Co., Ltd. | 皮膚疾患治療剤 |
| AU2008230949B2 (en) | 2007-03-23 | 2013-05-30 | The Board Of Regents Of The University Of Texas System | Methods involving aldose reductase inhibitors |
| JP5976010B2 (ja) * | 2010-12-23 | 2016-08-23 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | Copdを処置する方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| EP0006352A1 (en) * | 1978-06-15 | 1980-01-09 | Beecham Group Plc | Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them |
| CH638975A5 (fr) * | 1979-07-27 | 1983-10-31 | Prebuilt Ets | Composition medicamenteuse pour le traitement des ulceres gastro-duodenaux. |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| US4717725A (en) * | 1984-04-11 | 1988-01-05 | Alcon Laboratories, Inc. | Ophthalmic wound healing with aldose reductase inhibitors |
| US4600717A (en) * | 1984-04-11 | 1986-07-15 | Alcon Laboratories, Inc. | Aldose reductase inhibitors useful in ophthalmic wound healing |
| DE3769066D1 (de) * | 1986-08-28 | 1991-05-08 | Sanwa Kagaku Kenkyusho Co | Hydantoin-derivate zur behandlung von komplikationen bei diabetes. |
| DK0384416T3 (da) * | 1989-02-22 | 1994-02-28 | Sanwa Kagaku Kenkyusho Co | Farmaceutisk sammensætning indeholdende hydantoinderivat |
-
1990
- 1990-01-12 JP JP2005773A patent/JPH03215435A/ja active Pending
- 1990-10-22 US US07/600,872 patent/US5155125A/en not_active Expired - Fee Related
- 1990-11-02 DE DE69022206T patent/DE69022206T2/de not_active Expired - Fee Related
- 1990-11-02 ES ES90312053T patent/ES2078319T3/es not_active Expired - Lifetime
- 1990-11-02 DK DK90312053.3T patent/DK0437025T3/da active
- 1990-11-02 EP EP90312053A patent/EP0437025B1/en not_active Expired - Lifetime
- 1990-11-02 AT AT90312053T patent/ATE127344T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE127344T1 (de) | 1995-09-15 |
| DE69022206D1 (de) | 1995-10-12 |
| EP0437025B1 (en) | 1995-09-06 |
| DE69022206T2 (de) | 1996-04-18 |
| US5155125A (en) | 1992-10-13 |
| EP0437025A3 (en) | 1992-02-26 |
| DK0437025T3 (da) | 1995-12-18 |
| JPH03215435A (ja) | 1991-09-20 |
| EP0437025A2 (en) | 1991-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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