[go: up one dir, main page]

ES2063700A1 - Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan. - Google Patents

Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Info

Publication number
ES2063700A1
ES2063700A1 ES09300906A ES9300906A ES2063700A1 ES 2063700 A1 ES2063700 A1 ES 2063700A1 ES 09300906 A ES09300906 A ES 09300906A ES 9300906 A ES9300906 A ES 9300906A ES 2063700 A1 ES2063700 A1 ES 2063700A1
Authority
ES
Spain
Prior art keywords
agent
preparation
compositions containing
pharmaceutical compositions
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09300906A
Other languages
English (en)
Other versions
ES2063700B1 (es
Inventor
Ges Jose Maria Caldero
Vega Antonio Monge
Aldaz Berta Lasheras
Urdaci Ines Artaiz
Rio Zambrana Joaquin Del
Acin Joan Roca
Cubillo Juan Antonio Palop
Medrano Carmen Ranirez
Rovira Ana Bosch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vita Invest SA
Original Assignee
Vita Invest SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES09300906A priority Critical patent/ES2063700B1/es
Application filed by Vita Invest SA filed Critical Vita Invest SA
Priority to EP94913621A priority patent/EP0648766A1/en
Priority to RU94046382/04A priority patent/RU94046382A/ru
Priority to JP6523919A priority patent/JPH07508764A/ja
Priority to PCT/ES1994/000040 priority patent/WO1994025454A1/es
Priority to CA002139224A priority patent/CA2139224A1/en
Priority to AU65701/94A priority patent/AU6570194A/en
Publication of ES2063700A1 publication Critical patent/ES2063700A1/es
Application granted granted Critical
Publication of ES2063700B1 publication Critical patent/ES2063700B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

AGENTE ACTIVO SOBRE EL SISTEMA NERVIOSO CENTRAL, PROCESO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LO CONTENGAN. UN NUEVO DERIVADO DE 2-PIPERACINILINDOL, EL 3-[2-(1(4''PIPERONILPIPERACINIL))INDOLIL]CARBOXALDEHIDO, DE FORMULA (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, LOS PROCEDIMIENTOS PARA SU PREPARACION, SU USO COMO ANSIOLITICO, ANTIDEPRESIVO Y ESTIMULANTE DE LA MEMORIA Y LAS COMPOSICIONES QUE LO CONTIENEN.
ES09300906A 1993-04-28 1993-04-28 Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan. Expired - Fee Related ES2063700B1 (es)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES09300906A ES2063700B1 (es) 1993-04-28 1993-04-28 Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
RU94046382/04A RU94046382A (ru) 1993-04-28 1994-04-26 Агент, действующий на центральную нервную систему, способ его получения и фармацевтическая композиция, содержащая его
JP6523919A JPH07508764A (ja) 1993-04-28 1994-04-26 中枢神経系で作用する物質,その製造方法及びこのような物質を含有した医薬組成物
PCT/ES1994/000040 WO1994025454A1 (es) 1993-04-28 1994-04-26 Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan
EP94913621A EP0648766A1 (en) 1993-04-28 1994-04-26 Agent acting on the central nervous system, method for its preparation and pharmaceutical compositions containing such agent
CA002139224A CA2139224A1 (en) 1993-04-28 1994-04-26 Agent acting on the central nervous system, method for its preparation and pharmaceutical compositions containing such agent
AU65701/94A AU6570194A (en) 1993-04-28 1994-04-26 Agent acting on the central nervous system, method for its preparation and pharmaceutical compositions containing such agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09300906A ES2063700B1 (es) 1993-04-28 1993-04-28 Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Publications (2)

Publication Number Publication Date
ES2063700A1 true ES2063700A1 (es) 1995-01-01
ES2063700B1 ES2063700B1 (es) 1995-07-16

Family

ID=8281639

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09300906A Expired - Fee Related ES2063700B1 (es) 1993-04-28 1993-04-28 Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Country Status (7)

Country Link
EP (1) EP0648766A1 (es)
JP (1) JPH07508764A (es)
AU (1) AU6570194A (es)
CA (1) CA2139224A1 (es)
ES (1) ES2063700B1 (es)
RU (1) RU94046382A (es)
WO (1) WO1994025454A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ523436A (en) * 2000-07-21 2004-07-30 H Indole derivatives useful for the treatment of CNS discorders
AR032712A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187680A (en) * 1967-11-15 1970-04-15 Science Union & Cie New Heterocyclic Substituted Piperazines
ES439870A3 (es) * 1975-07-31 1977-03-16 Rocador Sa Procedimiento para la obtencion de nuevas amidas de la pipe-ronil-piperazina.
ES453269A1 (es) * 1976-11-12 1977-11-16 Boehringer Mannheim Gmbh Procedimiento para la obtencion de n-3, 4 metilendioxibencil-n' 3, 7, 11-trimetil 2, 6, 10 dodecatrienilpiperazina.
ES479628A1 (es) * 1978-04-27 1979-11-01 Farmaceutici Geymonat Sud Un procedimiento para preparar clorhidrato de p-clorofenoxia-acetil-piperonilpiperacina.
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2131826A1 (en) * 1971-03-29 1972-11-17 Anvar 3-carbonyl and thiocarbonyl-2-aminoindoles - with sedative activity
DE2557341A1 (de) * 1975-12-19 1977-06-30 Hoechst Ag Basisch substituierte indolderivate und verfahren zu ihrer herstellung
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187680A (en) * 1967-11-15 1970-04-15 Science Union & Cie New Heterocyclic Substituted Piperazines
ES439870A3 (es) * 1975-07-31 1977-03-16 Rocador Sa Procedimiento para la obtencion de nuevas amidas de la pipe-ronil-piperazina.
ES453269A1 (es) * 1976-11-12 1977-11-16 Boehringer Mannheim Gmbh Procedimiento para la obtencion de n-3, 4 metilendioxibencil-n' 3, 7, 11-trimetil 2, 6, 10 dodecatrienilpiperazina.
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
ES479628A1 (es) * 1978-04-27 1979-11-01 Farmaceutici Geymonat Sud Un procedimiento para preparar clorhidrato de p-clorofenoxia-acetil-piperonilpiperacina.

Also Published As

Publication number Publication date
RU94046382A (ru) 1996-10-27
JPH07508764A (ja) 1995-09-28
CA2139224A1 (en) 1994-11-10
ES2063700B1 (es) 1995-07-16
EP0648766A1 (en) 1995-04-19
AU6570194A (en) 1994-11-21
WO1994025454A1 (es) 1994-11-10

Similar Documents

Publication Publication Date Title
IE851918L (en) An indole derivative.
AU7493296A (en) 1-(1,2-disubstituted piperidinyl)-4-substituted piperazine derivatives
GB0004297D0 (en) 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
IL110131A0 (en) Arylidene and heteroarylidene oxindole derivatives, their preparation and pharmaceutical compositions containing them
CY2369B1 (en) Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same.
RU95101048A (ru) Производные пролинамида, фармкомпозиция на их основе
AU2337197A (en) Cinnamic acid derivatives and their use as integrin antagonists
TR199800077T1 (xx) Kontroll� ��z�len paroksetin terkipleri.
CA2174494A1 (en) Benzofurans
GB9322643D0 (en) Lactam derivatives
MX9800408A (es) Sales de derivados de amidina y de inhibidor de ciclooxigenasa, su procedimiento de preparacion, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
WO1999009025A3 (en) 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-1h-indole derivatives interacting with the dopamine d4 receptor
WO2000039083A3 (en) Pyrazole compounds and uses thereof
GB9718903D0 (en) Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
ZA961069B (en) Heterocyclic derivatives
EP1666041A3 (en) Xanthine derivatives for treating neurodegenerative disorders
GB2311780B (en) Pharmaceutical Piperazine Compounds
MY133169A (en) Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect
ES2111492A1 (es) Derivados de 1-(2-(vinilo substituido))-3,4-dihidro-5h-2,3-benzodiazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizacion de dichos derivados y composiciones para el tratamiento de trastornos del sistema nervioso central.
ES2063700A1 (es) Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
WO1998031704A3 (en) Tachykinin antagonists
YU140491A (sh) 6-supstituisani-tetrahidrobenz(c,d) indoli
EP0900796A4 (en) MEDICINES FOR THE PREVENTION AND TREATMENT OF LESIONS AND ILLEUS BY INTESTINAL ISCHEMIA
CA2175420A1 (en) Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403