ES2056337T3 - Utilizacion de antagonistas de receptores de tromboxano-a2 para evitar modificaciones degenerativas en el tejido penil. - Google Patents
Utilizacion de antagonistas de receptores de tromboxano-a2 para evitar modificaciones degenerativas en el tejido penil.Info
- Publication number
- ES2056337T3 ES2056337T3 ES90121343T ES90121343T ES2056337T3 ES 2056337 T3 ES2056337 T3 ES 2056337T3 ES 90121343 T ES90121343 T ES 90121343T ES 90121343 T ES90121343 T ES 90121343T ES 2056337 T3 ES2056337 T3 ES 2056337T3
- Authority
- ES
- Spain
- Prior art keywords
- thromboxane
- penile
- fabric
- tissue
- receptor antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000003938 Thromboxane Receptors Human genes 0.000 title 1
- 108090000300 Thromboxane Receptors Proteins 0.000 title 1
- 230000003412 degenerative effect Effects 0.000 title 1
- 239000004744 fabric Substances 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 239000005557 antagonist Substances 0.000 abstract 2
- 230000007850 degeneration Effects 0.000 abstract 2
- 230000005786 degenerative changes Effects 0.000 abstract 2
- 210000005225 erectile tissue Anatomy 0.000 abstract 2
- 210000003899 penis Anatomy 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- IULOBWFWYDMECP-UHFFFAOYSA-N 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]acetic acid Chemical compound C1=CC(CC(=O)O)=CC=C1CCNS(=O)(=O)C1=CC=C(Cl)C=C1 IULOBWFWYDMECP-UHFFFAOYSA-N 0.000 abstract 1
- WXNZTHHGJRFXKQ-UHFFFAOYSA-N 4-chlorophenol Chemical compound OC1=CC=C(Cl)C=C1 WXNZTHHGJRFXKQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010003694 Atrophy Diseases 0.000 abstract 1
- 230000037444 atrophy Effects 0.000 abstract 1
- 210000003855 cell nucleus Anatomy 0.000 abstract 1
- 229950008150 daltroban Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000003387 muscular Effects 0.000 abstract 1
- 229960003424 phenylacetic acid Drugs 0.000 abstract 1
- 239000003279 phenylacetic acid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Prostheses (AREA)
Abstract
LA PRESENTE INVENCION TRATA DE LA UTILIZACION DEL RECEPTOR DE ANTAGONISTAS TROMBOXAN (TX)-A SUB 2 PARA LA FABRICACION DE UN MEDICAMENTO PARA IMPEDIR CAMBIOS DEGENERATIVOS EN EL TEJIDO DEL PENE. CAMBIOS ESENCIALES POR LA DEGENERACION DEL TEJIDO DEL PENE QUE MOTIVAN UNA INSUFICIENCIA EN DIFERENTES GRADOS DEL TEJIDO ERECTIL SON LA ATROFIA DEL TEJIDO ERECTIL, LA DEGENERACION DEL NUCLEO CELULAR Y LA REDUCCION DE LOS FILAMENTOS MUSCULARES. LOS ANTAGONISTAS TROMBOXAN A SUB 2, EN PARTICULAR DALTROBAN (4(2-(4-CLOROFENOL)-SULFONILAMINOETIL)-ACIDO FENILACETICO), SON CAPACES DE REDUCIR ESTOS CAMBIOS DEGENERATIVOS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP90121343A EP0484581B1 (de) | 1990-11-08 | 1990-11-08 | Verwendung von Thromboxan-A2-Antagonisten zur Verhinderung von degenerativen Vorgängen im penilen Gewebe |
| CA002076005A CA2076005A1 (en) | 1990-11-08 | 1990-12-22 | Use of thromboxane-a2-receptor antagonists for the prevention of reduction of degenerative process in the penile tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2056337T3 true ES2056337T3 (es) | 1994-10-01 |
Family
ID=25675428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90121343T Expired - Lifetime ES2056337T3 (es) | 1990-11-08 | 1990-11-08 | Utilizacion de antagonistas de receptores de tromboxano-a2 para evitar modificaciones degenerativas en el tejido penil. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5192806A (es) |
| EP (1) | EP0484581B1 (es) |
| AT (1) | ATE107164T1 (es) |
| CA (1) | CA2076005A1 (es) |
| DE (1) | DE59006158D1 (es) |
| DK (1) | DK0484581T3 (es) |
| ES (1) | ES2056337T3 (es) |
| WO (1) | WO1992011005A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9203277A (pt) * | 1992-08-21 | 1994-03-01 | Cesar Roberto Dias Nahoum | Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao |
| US5773457A (en) * | 1995-02-15 | 1998-06-30 | Cesar Roberto Dias Nahoum | Compositions |
| US5718917A (en) * | 1995-12-15 | 1998-02-17 | Harvard Scientific Corporation | PGE-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction |
| JP2005232148A (ja) * | 2004-02-03 | 2005-09-02 | Technion Research & Development Foundation Ltd | 神経保護剤としてプロパルギルアミンの使用 |
-
1990
- 1990-11-08 EP EP90121343A patent/EP0484581B1/de not_active Expired - Lifetime
- 1990-11-08 DK DK90121343.9T patent/DK0484581T3/da active
- 1990-11-08 AT AT90121343T patent/ATE107164T1/de not_active IP Right Cessation
- 1990-11-08 DE DE59006158T patent/DE59006158D1/de not_active Expired - Fee Related
- 1990-11-08 ES ES90121343T patent/ES2056337T3/es not_active Expired - Lifetime
- 1990-12-22 WO PCT/EP1990/002299 patent/WO1992011005A1/de not_active Ceased
- 1990-12-22 CA CA002076005A patent/CA2076005A1/en not_active Abandoned
-
1991
- 1991-04-15 US US07/684,740 patent/US5192806A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0484581B1 (de) | 1994-06-15 |
| DK0484581T3 (da) | 1994-10-24 |
| ATE107164T1 (de) | 1994-07-15 |
| WO1992011005A1 (de) | 1992-07-09 |
| EP0484581A1 (de) | 1992-05-13 |
| DE59006158D1 (de) | 1994-07-21 |
| US5192806A (en) | 1993-03-09 |
| CA2076005A1 (en) | 1992-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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