[go: up one dir, main page]

ES2053981T3 - Composicion de revestimiento farmaceutica de base acuosa para formas de dosificacion. - Google Patents

Composicion de revestimiento farmaceutica de base acuosa para formas de dosificacion.

Info

Publication number
ES2053981T3
ES2053981T3 ES89303289T ES89303289T ES2053981T3 ES 2053981 T3 ES2053981 T3 ES 2053981T3 ES 89303289 T ES89303289 T ES 89303289T ES 89303289 T ES89303289 T ES 89303289T ES 2053981 T3 ES2053981 T3 ES 2053981T3
Authority
ES
Spain
Prior art keywords
coating composition
dosage forms
water based
based pharmaceutical
pharmaceutical coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89303289T
Other languages
English (en)
Inventor
David Emil Edgren
Felix Theeuwes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2053981T3 publication Critical patent/ES2053981T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

SE PRESENTA UNA FORMA DE DOSIFICACION QUE COMPRENDE UN RECUBRIMIENTO QUE RODEA A LA DROGA. EL RECUBRIMIENTO COMPRENDE UN SUBRECUBRIMIENTO Y UN SUPRACUBRIMIENTO TEMPLADO TERMICAMENTE PARA PROVEER UN RECUBRIMIENTO DE UNIDAD SIMPLE ALREDEDOR DE LA DROGA.
ES89303289T 1988-04-28 1989-04-04 Composicion de revestimiento farmaceutica de base acuosa para formas de dosificacion. Expired - Lifetime ES2053981T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/187,621 US4931285A (en) 1988-04-28 1988-04-28 Aqueous based pharmaceutical coating composition for dosage forms

Publications (1)

Publication Number Publication Date
ES2053981T3 true ES2053981T3 (es) 1994-08-01

Family

ID=22689748

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89303289T Expired - Lifetime ES2053981T3 (es) 1988-04-28 1989-04-04 Composicion de revestimiento farmaceutica de base acuosa para formas de dosificacion.

Country Status (11)

Country Link
US (1) US4931285A (es)
EP (1) EP0339811B1 (es)
JP (1) JP2581798B2 (es)
AT (1) ATE85519T1 (es)
CA (1) CA1337275C (es)
DE (1) DE68904801T2 (es)
DK (1) DK205889A (es)
ES (1) ES2053981T3 (es)
GR (1) GR3007032T3 (es)
IE (1) IE62132B1 (es)
PT (1) PT90418B (es)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024842A (en) * 1988-04-28 1991-06-18 Alza Corporation Annealed coats
US5126146A (en) * 1989-10-23 1992-06-30 Merck & Co., Inc. Cellulosic coating
AU657114B2 (en) * 1991-01-16 1995-03-02 Fmc Corporation Carrier for active agents, and solid dosage forms prepared therewith
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
US5178867A (en) * 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
GB9311191D0 (en) * 1993-05-29 1993-07-14 Danbiosyst Uk Controlled release drug formulation
GB9609094D0 (en) * 1996-05-01 1996-07-03 Univ Strathclyde Delivery device
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
PT1014951E (pt) 1997-09-09 2005-03-31 Alza Corp Composicao de revestimento farmaceutica e metodo para a sua utilizacao
US7060734B1 (en) 1997-09-09 2006-06-13 Alza Corporation Pharmaceutical coating composition and method of use
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
DK1035834T3 (da) * 1997-12-05 2002-07-08 Alza Corp Osmotisk doseringsform omfattende en første og anden coating
KR100576583B1 (ko) * 1997-12-22 2006-05-04 알자 코포레이션 서방성 약물 송달 장치용 속도 조절막
EP1652516A3 (en) 1998-11-02 2006-05-17 ALZA Corporation Osmotic controlled delivery of active agents
US6706282B1 (en) 1998-11-02 2004-03-16 Evangeline Cruz Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6635281B2 (en) 1998-12-23 2003-10-21 Alza Corporation Gastric retaining oral liquid dosage form
JP3672008B2 (ja) * 1999-01-20 2005-07-13 シオノギクオリカプス株式会社 硬質カプセル及びその製造方法
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
GB0114746D0 (en) * 2001-06-16 2001-08-08 Boots Co Plc Medicinal composition
JP4848101B2 (ja) 2001-08-17 2011-12-28 株式会社フジモト・コーポレーション 徐放性マイクロペレット
US8329217B2 (en) * 2001-11-06 2012-12-11 Osmotica Kereskedelmi Es Szolgaltato Kft Dual controlled release dosage form
US20030185882A1 (en) * 2001-11-06 2003-10-02 Vergez Juan A. Pharmaceutical compositions containing oxybutynin
JP4031232B2 (ja) * 2001-11-09 2008-01-09 カプスゲル・ジャパン株式会社 新規カプセル
EP1458353A1 (en) * 2001-12-19 2004-09-22 ALZA Corporation Formulation dosage form for the controlled delivery of ther apeutic agents
NZ533060A (en) * 2001-12-19 2006-03-31 Alza Corp Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
NZ536252A (en) * 2002-04-29 2007-06-29 Alza Corp Methods and dosage forms for controlled delivery of oxycodone
NZ536693A (en) * 2002-05-31 2007-01-26 Alza Corp Controlled release dosage forms and compositions for osmotic delivery of variable dosages of oxycodone
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
US20050175690A1 (en) * 2003-12-29 2005-08-11 David Edgren Novel drug compositions and dosage forms
JP2005536568A (ja) * 2002-07-29 2005-12-02 アルザ・コーポレーシヨン トピラメートの調節分配用の調剤および投薬形態
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
CH696420A5 (de) * 2002-09-13 2007-06-15 Mepha Ag Neue stabile Zubereitungen von Alkyl-, Phenyl-Pyridonen für topische Anwendung.
UY28057A1 (es) * 2002-10-31 2003-12-31 Alza Corp Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos
SI1575569T1 (sl) 2002-12-13 2010-12-31 Durect Corp Oralni sistem dostave zdravila, ki obsega visokoviskozne tekoče nosilne materiale
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
KR20050095835A (ko) * 2003-01-14 2005-10-04 알자 코포레이션 조정된 점성층을 갖는 방법 및 제형
EP1592410B1 (en) * 2003-02-11 2008-07-23 Alza Corporation Methods and dosage forms with modified layer geometry
JP2007501248A (ja) * 2003-08-06 2007-01-25 アルザ・コーポレーシヨン 増進した分散調合物による長時間にわたるトピラメートの均一送達
JP2007503389A (ja) * 2003-08-22 2007-02-22 アルザ・コーポレーシヨン 長期間にわたるトピラメートの段階的送達
EP1701697A2 (en) * 2003-09-02 2006-09-20 ALZA Corporation Novel drug compositions and dosage forms of topiramate
NZ586198A (en) * 2003-09-26 2011-12-22 Alza Corp Oros push-stick sustained release dosage forms for controlled delivery of active agents
BRPI0414802A (pt) * 2003-09-26 2006-11-14 Alza Corp formas de dosagem osmóticas para liberação controlada de alprazolam
US20070259033A1 (en) * 2003-09-26 2007-11-08 Evangeline Cruz Controlled release formulations exhibiting an ascending rate of release
US20050158382A1 (en) * 2003-09-26 2005-07-21 Evangeline Cruz Controlled release formulations of opioid and nonopioid analgesics
EP2184058B1 (en) 2003-09-26 2012-02-08 ALZA Corporation Drug coating providing high drug loading and methods for providing the same
US20050129765A1 (en) * 2003-11-14 2005-06-16 Shaoling Li Controlled release of topiramate in liquid dosage forms
BRPI0416535A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc processo de congelamento por vaporização empregando um extrusor para preparar composições de azitromicina de multiparticulado contendo preferivelmente um poloxámero e um glicerìdeo
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
ATE399536T1 (de) * 2003-12-04 2008-07-15 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
EP1689368B1 (en) * 2003-12-04 2016-09-28 Bend Research, Inc Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions
AU2004294818A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Azithromycin multiparticulate dosage forms by liquid-based processes
EP1691786A1 (en) * 2003-12-04 2006-08-23 Pfizer Products Inc. Multiparticulate compositions with improved stability
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
CA2550866A1 (en) * 2003-12-23 2005-07-14 Alza Corporation Methods and dosage forms for increasing solubility of drug compositions for controlled delivery
WO2005065648A2 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc., Novel drug compositions and dosage forms of topiramate
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
WO2006007323A2 (en) * 2004-06-28 2006-01-19 Alza Corporation Dosage forms for low solubility and/or low dissolution rate free acid pharmaceutical agents
CA2577583A1 (en) * 2004-08-19 2006-03-02 Alza Corporation Controlled release nanoparticle active agent formulation dosage forms and methods
US8541026B2 (en) * 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
WO2006113568A2 (en) * 2005-04-19 2006-10-26 Alza Corporation Controlled delivery dosage form of tramadol and gabapentin
KR20080030637A (ko) * 2005-06-29 2008-04-04 알자 코포레이션 삼투성 제형에 대하여 감소된 건조 시간을 제공하는반투과성 조성물
DE102005031577A1 (de) 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
AR055099A1 (es) * 2005-07-28 2007-08-08 Alza Corp Formulaciones liquidas para la administracion controlada de derivados de bencisoxazol
WO2007019393A2 (en) * 2005-08-04 2007-02-15 Alza Corporation Osmotic dosage forms comprising semipermeable membranes with polymer blends providing improved properties
EP1933811A2 (en) * 2005-09-30 2008-06-25 Alza Corporation Banded controlled release nanoparticle active agent formulation dosage forms and methods
PL116330U1 (en) 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US20070196487A1 (en) * 2006-02-16 2007-08-23 Geerke Johan H Method and apparatus for drilling orifices in osmotic tablets incorporating near-infrared spectroscopy
MX2008014870A (es) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas.
MX2009001114A (es) 2006-08-09 2009-02-10 Intarcia Therapeutics Inc Sistemas de suministro osmotico y ensambles de piston.
WO2008042802A2 (en) * 2006-09-29 2008-04-10 Sensient Pharmaceutical Technologies Inc. Wet edible pearlescent film coatings
PL2099312T3 (pl) * 2006-12-14 2016-10-31 Kompozycje pigmentów perłowych oraz sposoby ich wytwarzania i zastosowania
US8524749B2 (en) * 2007-02-09 2013-09-03 Alza Corporation Controlled release compositions of tizanidine
CN104000779A (zh) 2007-04-23 2014-08-27 精达制药公司 促胰岛素释放肽的混悬制剂及其应用
EP2067471B1 (en) 2007-12-06 2018-02-14 Durect Corporation Oral pharmaceutical dosage forms
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
DE102008059206A1 (de) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
DK2462246T3 (da) 2009-09-28 2017-11-06 Intarcia Therapeutics Inc Hurtig etablering og/eller afslutning af væsentlig steady-state-lægemiddelafgivelse
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
MX2014013320A (es) 2012-05-07 2015-08-10 Bayer Pharma AG Procedimiento de fabricacion de una forma de dosificacion farmaceutica que comprende nifedipina y candesartan cilexetilo.
CA2905131A1 (en) 2013-03-15 2014-09-18 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
WO2016040650A1 (en) * 2014-09-10 2016-03-17 University Of Rochester Soluble guanylyl cyclase inhibition effects on lymphatic vasculature
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
MA53353A (fr) 2016-05-16 2021-06-09 Intarcia Therapeutics Inc Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
JP7258561B2 (ja) 2016-07-06 2023-04-17 オリエント ファーマ シーオー.,エルティーディー. 薬物組成物、バリヤー層及び薬物層を有している経口投与形態
KR20190104039A (ko) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2799241A (en) * 1949-01-21 1957-07-16 Wisconsin Alumni Res Found Means for applying coatings to tablets or the like
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916889A (en) * 1973-09-28 1975-11-04 Sandoz Ag Patient ventilator apparatus
ZA753851B (en) * 1974-08-01 1976-05-26 Ici Ltd Film coating process
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4002174A (en) * 1975-10-14 1977-01-11 Texas Medical Products, Inc. Air embolus aspirator
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4014334A (en) * 1976-02-02 1977-03-29 Alza Corporation Laminated osmotic system for dispensing beneficial agent
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4207893A (en) * 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
GB2170104A (en) * 1985-01-30 1986-07-30 Warner Lambert Co Coated pharmaceutical dosage forms

Also Published As

Publication number Publication date
GR3007032T3 (es) 1993-07-30
PT90418A (pt) 1989-11-10
IE62132B1 (en) 1994-12-14
DK205889D0 (da) 1989-04-27
DE68904801D1 (de) 1993-03-25
JPH0211526A (ja) 1990-01-16
US4931285A (en) 1990-06-05
DK205889A (da) 1989-10-29
DE68904801T2 (de) 1993-05-27
CA1337275C (en) 1995-10-10
PT90418B (pt) 1994-05-31
JP2581798B2 (ja) 1997-02-12
IE891116L (en) 1989-10-28
EP0339811A3 (en) 1990-11-07
EP0339811A2 (en) 1989-11-02
ATE85519T1 (de) 1993-02-15
EP0339811B1 (en) 1993-02-10

Similar Documents

Publication Publication Date Title
ES2053981T3 (es) Composicion de revestimiento farmaceutica de base acuosa para formas de dosificacion.
NO903925D0 (no) Fremgangsmaate for fremstilling av 3-(1-substituert-4-piperazinyl)-1h-indazoler samt anvendelse som legemidler.
ES2051698T3 (es) Granulos destinados a permanecer en el estomago.
DE3650657D1 (de) Pharmazeutische Formulierung mit gesteuerter Freigabe
NO883918D0 (no) Beleggsformulering for bioaktive stoffer med kontrollert utloesning.
ES2041699T3 (es) Procedimiento de preparacion de un medicamento a base de fenofibrato y medicamento obtenido por este procedimiento.
BR9100843A (pt) Inalador e embalagem de medicamento para aplicacao com o mesmo
CA2145513A1 (en) Pharmaceutical Tablet Capable of Liberating One or More Drugs at Different Release Rates
IT8621358A0 (it) Composizione farmaceutica adattivita' analgesica.
DE68924575D1 (de) Schutzüberzugsfilm.
ES556452A0 (es) Procedimiento para la preparacion de formas de administracion de medicamentos solidas y duraderas a base de hidroxipropilcelulosa.
IT1230174B (it) Dispositivo a denti con rivestimento riflettente per l'irradiazione di luce sul cuoio capelluto.
NO913296D0 (no) Sammensatte folie- og platematerialer med et topplag av hoeymolekylert polyetylen, samt fremgangsmaate for fremstilling av slike.
FI955260L (fi) Transdermaalisia terapeuttisia systeemejä serotoniiniagonistien antamista varten
FI891865A7 (fi) Atselastiinia sisältäviä lääkkeitä, joista vaikuttava aine vapautuu säädellysti
IT8921898A0 (it) Procedimento e dispositivo per l'applicazione di fascette su confezioni.
DK298389A (da) Farmaceutisk praeparat til topisk anvendelse omfattende et amin-funktionelt medikament
ES1004915Y (es) Dispositivo para vaporizar sustancias termicamente vaporizables.
KR880700031A (ko) 가요성 기질용 피복 조성물, 그의 용도 및 보호 피막의 생성방법
IT8805224A0 (it) Composizione a base di poliesteri per la liberazione controllata di sostanze medicamentose.
NO891574D0 (no) Fremgangsmaate for fremstilling av farmasoeytisk anvendbareforbindelser.
DE68903214D1 (de) Duesenbeschichtungs vorrichtung.
IT8348781A0 (it) Attivita' antiflogistica, analgesica, antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzo ilpirrol-2-acetamido acetanilidi
DK89188D0 (da) Forstoevningsdyse
IT214895Z2 (it) Dispositivo nebulizzatore per smalti e simili

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 339811

Country of ref document: ES