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ES2040733T3 - Medicamentos que contienen clodronato y procedimiento para su preparacion. - Google Patents

Medicamentos que contienen clodronato y procedimiento para su preparacion.

Info

Publication number
ES2040733T3
ES2040733T3 ES198787118364T ES87118364T ES2040733T3 ES 2040733 T3 ES2040733 T3 ES 2040733T3 ES 198787118364 T ES198787118364 T ES 198787118364T ES 87118364 T ES87118364 T ES 87118364T ES 2040733 T3 ES2040733 T3 ES 2040733T3
Authority
ES
Spain
Prior art keywords
clodronate
lubricant
procedure
preparation
medicines containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787118364T
Other languages
English (en)
Inventor
Fritz Dr. Rer. Nat. Demmer
Berthold Dr. Rer. Nat. Stemmle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2040733T3 publication Critical patent/ES2040733T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

EL INVENTO SE REFIERE A UN MEDICAMENTO CONTENIDO DE SUSTANCIA ACTIVA ENTRE UN 80 Y 95% Y UN PROCEDIMIENTO PARA SU PREPARACION. LA SUSTANCIA ACTIVA SE GRANULA CON UN 2 A 10% DE MATERIAL RELLENO Y CON UN 0 A 5% DE MEDIOS LUBRIFICANTES. EL GRANULADO SE MEZCLA CON 1 A 5% DE SUSTANCIA LUBRIFICANTE Y LA MEZCLA SE PRENSA PARA HECER TABLETAS O SE RELLENA EN CAPSULAS. EL MEDICAMENTO POSEE UN CONTENIDO DE SUBSTANCIA ACTIVAS DE 400 A 1000MG POR DOSIS INDIVIDUAL.
ES198787118364T 1986-12-20 1987-12-11 Medicamentos que contienen clodronato y procedimiento para su preparacion. Expired - Lifetime ES2040733T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3643758 1986-12-20

Publications (1)

Publication Number Publication Date
ES2040733T3 true ES2040733T3 (es) 1993-11-01

Family

ID=6316771

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787118364T Expired - Lifetime ES2040733T3 (es) 1986-12-20 1987-12-11 Medicamentos que contienen clodronato y procedimiento para su preparacion.

Country Status (9)

Country Link
US (1) US4859472A (es)
EP (1) EP0275468B1 (es)
AT (1) ATE60711T1 (es)
CA (1) CA1298196C (es)
DE (1) DE3767998D1 (es)
DK (1) DK174893B1 (es)
ES (1) ES2040733T3 (es)
GR (1) GR3001615T3 (es)
HK (1) HK59894A (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0587744B1 (en) * 1991-05-28 2003-07-16 McNEIL-PPC, Inc. Chewable drug-delivery composition
US5314696A (en) * 1991-06-27 1994-05-24 Paulos Manley A Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
SE501389C2 (sv) * 1992-04-24 1995-01-30 Leiras Oy Farmaceutiskt preparat och förfarande för dess framställning
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
US6406714B1 (en) 1992-12-02 2002-06-18 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids
ATE128363T1 (de) * 1993-05-15 1995-10-15 Boehringer Mannheim Gmbh Tablette mit verbesserter bioverfügbarkeit enthaltend dichlormethylendiphosphonsäure als wirkstoff.
FI94926C (fi) * 1993-11-12 1995-11-27 Leiras Oy Menetelmä klodronaattivalmisteen valmistamiseksi
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
FI109088B (fi) * 1997-09-19 2002-05-31 Leiras Oy Tabletti ja menetelmä sen valmistamiseksi
EP0998933A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Verfahren zur Herstellung von bisphosphonathaltigen pharmazeutischen Zusammensetzungen zur oralen Applikation
EP0998932A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
RO121891B1 (ro) 2001-07-04 2008-07-30 Sindan S.R.L. Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare
US7687482B2 (en) * 2006-03-17 2010-03-30 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods
US7358361B2 (en) * 2004-10-08 2008-04-15 The Board Of Trustees Of The University Of Illinois Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases
US8012949B2 (en) * 2004-10-08 2011-09-06 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS
FR2954320B1 (fr) 2009-12-17 2012-06-15 Cll Pharma Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels
EP3713581A1 (en) 2017-11-22 2020-09-30 Inbiomotion S.L. Therapeutic treatment of breast cancer based on c-maf

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1012003B (it) * 1967-12-11 1977-03-10 Procter & Gamble Composizioni veterinarie per inibi re anomalie nella deposizione e mo bilizzazione del fosfato di calcio nei tessuti animali
US3632778A (en) * 1970-06-10 1972-01-04 Hoffmann La Roche Tablets containing l-dopa
JPS5332111A (en) * 1976-09-07 1978-03-27 Asahi Chem Ind Co Ltd Composition for tablet
GB2043072B (en) * 1979-02-13 1983-11-23 Symphar Sa Diphosphonate compounds
CA1209040A (fr) * 1982-12-21 1986-08-05 Jean Bru Procede de fabrication de granules et comprimes effervescents
US4687662A (en) * 1985-08-30 1987-08-18 Warner-Lambert Company Therapeutic effervescent composition

Also Published As

Publication number Publication date
DK174893B1 (da) 2004-02-02
DE3767998D1 (de) 1991-03-14
US4859472A (en) 1989-08-22
EP0275468A1 (de) 1988-07-27
GR3001615T3 (en) 1992-11-23
CA1298196C (en) 1992-03-31
DK658387A (da) 1988-06-21
ATE60711T1 (de) 1991-02-15
HK59894A (en) 1994-07-08
DK658387D0 (da) 1987-12-15
EP0275468B1 (de) 1991-02-06

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