EP4424843A3 - Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn - Google Patents
Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn Download PDFInfo
- Publication number
- EP4424843A3 EP4424843A3 EP24169592.3A EP24169592A EP4424843A3 EP 4424843 A3 EP4424843 A3 EP 4424843A3 EP 24169592 A EP24169592 A EP 24169592A EP 4424843 A3 EP4424843 A3 EP 4424843A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- rna
- methods
- spatial analysis
- templated ligation
- templated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP25198895.2A EP4667585A2 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962952736P | 2019-12-23 | 2019-12-23 | |
| US202062969458P | 2020-02-03 | 2020-02-03 | |
| US202063087061P | 2020-10-02 | 2020-10-02 | |
| US202063108088P | 2020-10-30 | 2020-10-30 | |
| PCT/US2020/066720 WO2021133849A1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale utilisant une ligature à matrice d'arn |
| EP20842882.1A EP3891300B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale utilisant une ligature à matrice d'arn |
| EP23157353.6A EP4219754B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Related Parent Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20842882.1A Division EP3891300B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale utilisant une ligature à matrice d'arn |
| EP23157353.6A Division EP4219754B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
| EP23157353.6A Division-Into EP4219754B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP25198895.2A Division EP4667585A2 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| EP4424843A2 EP4424843A2 (fr) | 2024-09-04 |
| EP4424843A3 true EP4424843A3 (fr) | 2024-09-25 |
| EP4424843C0 EP4424843C0 (fr) | 2025-09-03 |
| EP4424843B1 EP4424843B1 (fr) | 2025-09-03 |
Family
ID=74191967
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP23157353.6A Active EP4219754B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
| EP24169592.3A Active EP4424843B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
| EP20842882.1A Active EP3891300B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale utilisant une ligature à matrice d'arn |
| EP25198895.2A Pending EP4667585A2 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP23157353.6A Active EP4219754B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20842882.1A Active EP3891300B1 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale utilisant une ligature à matrice d'arn |
| EP25198895.2A Pending EP4667585A2 (fr) | 2019-12-23 | 2020-12-22 | Procédés d'analyse spatiale à l'aide d'une ligature à matrice d'arn |
Country Status (9)
| Country | Link |
|---|---|
| US (9) | US11505828B2 (fr) |
| EP (4) | EP4219754B1 (fr) |
| CN (2) | CN121022991A (fr) |
| AU (2) | AU2020412766C1 (fr) |
| DK (1) | DK3891300T3 (fr) |
| ES (2) | ES2982420T3 (fr) |
| FI (1) | FI3891300T3 (fr) |
| SG (1) | SG11202106899SA (fr) |
| WO (1) | WO2021133849A1 (fr) |
Families Citing this family (110)
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| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
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| LT3013983T (lt) | 2013-06-25 | 2023-05-10 | Prognosys Biosciences, Inc. | Erdviniai koduoti biologiniai tyrimai, naudojant mikrofluidinį įrenginį |
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| SG10202107055SA (en) | 2015-07-17 | 2021-08-30 | Nanostring Technologies Inc | Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue |
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