[go: up one dir, main page]

EP3423597A4 - METHODS, COMPOSITIONS AND DEVICES FOR STORING INFORMATION - Google Patents

METHODS, COMPOSITIONS AND DEVICES FOR STORING INFORMATION Download PDF

Info

Publication number
EP3423597A4
EP3423597A4 EP17760661.3A EP17760661A EP3423597A4 EP 3423597 A4 EP3423597 A4 EP 3423597A4 EP 17760661 A EP17760661 A EP 17760661A EP 3423597 A4 EP3423597 A4 EP 3423597A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
devices
storing information
storing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17760661.3A
Other languages
German (de)
French (fr)
Other versions
EP3423597A2 (en
Inventor
Paul Predki
Maja CASSIDY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iridia Inc
Original Assignee
Iridia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iridia Inc filed Critical Iridia Inc
Publication of EP3423597A2 publication Critical patent/EP3423597A2/en
Publication of EP3423597A4 publication Critical patent/EP3423597A4/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00511Walls of reactor vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00Reaction characterised by the enzymatic activity
    • C12Q2521/10Nucleotidyl transfering
    • C12Q2521/131Terminal transferase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/116Nucleic acid detection characterized by the use of physical, structural and functional properties electrical properties of nucleic acids, e.g. impedance, conductivity or resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60Detection means characterised by use of a special device
    • C12Q2565/631Detection means characterised by use of a special device being a biochannel or pore
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y599/00Other isomerases (5.99)
    • C12Y599/01Other isomerases (5.99.1)
    • C12Y599/01002DNA topoisomerase (5.99.1.2)
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/12Computing arrangements based on biological models using genetic models
    • G06N3/123DNA computing
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009RRAM elements whose operation depends upon chemical change
    • G11C13/0014RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009RRAM elements whose operation depends upon chemical change
    • G11C13/0014RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Computation (AREA)
  • Computing Systems (AREA)
  • Artificial Intelligence (AREA)
  • Mathematical Physics (AREA)
  • Software Systems (AREA)
  • Electrochemistry (AREA)
  • Computational Linguistics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP17760661.3A 2016-02-29 2017-02-28 METHODS, COMPOSITIONS AND DEVICES FOR STORING INFORMATION Pending EP3423597A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662301538P 2016-02-29 2016-02-29
US201662415430P 2016-10-31 2016-10-31
PCT/US2017/020044 WO2017151680A2 (en) 2016-02-29 2017-02-28 Methods, compositions, and devices for information storage

Publications (2)

Publication Number Publication Date
EP3423597A2 EP3423597A2 (en) 2019-01-09
EP3423597A4 true EP3423597A4 (en) 2020-03-04

Family

ID=59743186

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17760661.3A Pending EP3423597A4 (en) 2016-02-29 2017-02-28 METHODS, COMPOSITIONS AND DEVICES FOR STORING INFORMATION

Country Status (13)

Country Link
EP (1) EP3423597A4 (en)
JP (2) JP7546345B2 (en)
KR (2) KR20250024857A (en)
CN (1) CN109415766A (en)
AU (2) AU2017227608B2 (en)
BR (1) BR112018067903A2 (en)
CA (1) CA3016037A1 (en)
IL (1) IL261424B (en)
MX (2) MX2018010388A (en)
PH (1) PH12018501843A1 (en)
RU (2) RU2765308C2 (en)
SG (1) SG11201807334SA (en)
WO (1) WO2017151680A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4137808A1 (en) 2016-01-28 2023-02-22 Roswell Biotechnologies, Inc. Method of making a sequencing device
JP7280590B2 (en) 2016-01-28 2023-05-24 ロズウェル バイオテクノロジーズ,インコーポレイテッド Methods and apparatus for measuring analytes using large-scale molecular electronics sensor arrays
KR102734671B1 (en) 2016-02-09 2024-11-25 로스웰 엠이 아이엔씨. Electronically labeled DNA and genome sequencing
US10597767B2 (en) 2016-02-22 2020-03-24 Roswell Biotechnologies, Inc. Nanoparticle fabrication
US10438662B2 (en) * 2016-02-29 2019-10-08 Iridia, Inc. Methods, compositions, and devices for information storage
US9829456B1 (en) 2016-07-26 2017-11-28 Roswell Biotechnologies, Inc. Method of making a multi-electrode structure usable in molecular sensing devices
CA3052062A1 (en) 2017-01-10 2018-07-19 Roswell Biotechnologies, Inc. Methods and systems for dna data storage
WO2018136148A1 (en) 2017-01-19 2018-07-26 Roswell Biotechnologies, Inc. Solid state sequencing devices comprising two dimensional layer materials
US10508296B2 (en) 2017-04-25 2019-12-17 Roswell Biotechnologies, Inc. Enzymatic circuits for molecular sensors
EP3615685B1 (en) 2017-04-25 2025-02-19 Roswell Biotechnologies, Inc Enzymatic circuits for molecular sensors
CA3057155A1 (en) 2017-05-09 2018-11-15 Roswell Biotechnologies, Inc. Binding probe circuits for molecular sensors
US11612873B2 (en) 2017-05-31 2023-03-28 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US11174512B2 (en) 2017-05-31 2021-11-16 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
KR102583062B1 (en) * 2017-05-31 2023-09-25 몰레큘러 어셈블리즈, 인크. Homopolymer encoded nucleic acid memory
US11371955B2 (en) 2017-08-30 2022-06-28 Roswell Biotechnologies, Inc. Processive enzyme molecular electronic sensors for DNA data storage
CN111373051A (en) * 2017-10-10 2020-07-03 罗斯威尔生命技术公司 Method, apparatus and system for amplitionless DNA data storage
GB2585506A (en) 2018-01-04 2021-01-13 Twist Bioscience Corp DNA-based digital information storage
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
EP3547315B1 (en) * 2018-03-26 2021-01-27 IMEC vzw Method of storing data
CN113302700B (en) * 2018-09-07 2024-10-08 艾瑞迪亚公司 Improved systems and methods for writing and reading data stored in polymers
CN113646073B (en) * 2019-03-29 2024-09-24 帕洛根公司 Nanopore device and biosynthesis method using the same
US11655465B1 (en) 2019-05-02 2023-05-23 Iridia, Inc. Enzymes and systems for synthesizing DNA
TWI860366B (en) * 2019-06-19 2024-11-01 美商伊路米納有限公司 Reagent exchange in an instrument
US11837302B1 (en) 2020-08-07 2023-12-05 Iridia, Inc. Systems and methods for writing and reading data stored in a polymer using nano-channels
CN114196661B (en) * 2021-11-04 2023-08-11 北京全式金生物技术股份有限公司 Recombinant topoisomerase and application thereof in construction of sequencing library
US12487229B2 (en) * 2021-12-08 2025-12-02 Western Digital Technologies, Inc. Devices, systems, and methods of using smart fluids to control molecule speeds
US11892445B2 (en) * 2021-12-08 2024-02-06 Western Digital Technologies, Inc. Devices, systems, and methods of using smart fluids to control translocation speed through a nanopore
CN117079689A (en) * 2022-05-10 2023-11-17 密码子(杭州)科技有限公司 Molecular module assembling device and molecular module assembling method
US12461064B2 (en) 2023-06-23 2025-11-04 Western Digital Technologies, Inc. Magnetic control of molecule translocation speed through a nanopore
WO2025212833A2 (en) * 2024-04-03 2025-10-09 Catalog Technologies, Inc. Liquid formulations for dna writing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040001371A1 (en) * 2002-06-26 2004-01-01 The Arizona Board Of Regents On Behalf Of The University Of Arizona Information storage and retrieval device using macromolecules as storage media

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681702A (en) * 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
AU746657B2 (en) * 1997-06-12 2002-05-02 Invitrogen Corporation Covalent joining of DNA strands to RNA strands catalyzed by vaccinia topoisomerase
CN101173276A (en) * 2000-12-08 2008-05-07 茵维特罗根公司 Compositions and methods for rapidly generating recombinant nucleic acid molecules
US7390622B2 (en) * 2003-10-16 2008-06-24 Hai Kang Life Corporation Limited Apparatus and methods for detecting nucleic acid in biological samples
US7972992B2 (en) * 2003-12-17 2011-07-05 Praecis Pharmaceuticals, Inc. Methods for synthesis of encoded libraries
WO2006122317A2 (en) * 2005-05-11 2006-11-16 The Regents Of The University Of California Nanofabrication processes and devices for the controlled assembly of functionalized nanostructures
US20060286024A1 (en) * 2005-06-15 2006-12-21 Baker R Terry K Synthesis and cleaving of carbon nanochips
DK2915564T3 (en) * 2007-09-28 2021-02-08 Alexion Pharma Inc Antidotes to factor XA inhibitors and methods for their use
JP5843614B2 (en) * 2009-01-30 2016-01-13 オックスフォード ナノポア テクノロジーズ リミテッド Adapters for nucleic acid constructs in transmembrane sequencing
CN103392008B (en) * 2010-09-07 2017-10-20 加利福尼亚大学董事会 Movement by continuation enzyme with the precision controlling DNA of a nucleotides in nano-pore
WO2013109970A1 (en) * 2012-01-20 2013-07-25 Genia Technologies, Inc. Nanopore based molecular detection and sequencing
US9322820B2 (en) * 2013-03-14 2016-04-26 Wisconsin Alumni Research Foundation System and apparatus for nanopore sequencing

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040001371A1 (en) * 2002-06-26 2004-01-01 The Arizona Board Of Regents On Behalf Of The University Of Arizona Information storage and retrieval device using macromolecules as storage media

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
G. M. CHURCH ET AL: "Next-Generation Digital Information Storage in DNA", SCIENCE, vol. 337, no. 6102, 28 September 2012 (2012-09-28), pages 1628 - 1628, XP055082578, ISSN: 0036-8075, DOI: 10.1126/science.1226355 *
MENI WANUNU: "Nanopores: A journey towards DNA sequencing", PHYSICS OF LIFE REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 9, no. 2, 15 May 2012 (2012-05-15), pages 125 - 158, XP028400139, ISSN: 1571-0645, [retrieved on 20120518], DOI: 10.1016/J.PLREV.2012.05.010 *

Also Published As

Publication number Publication date
AU2017227608A1 (en) 2018-09-27
IL261424A (en) 2018-10-31
KR20180123062A (en) 2018-11-14
IL261424B (en) 2021-08-31
RU2018134197A (en) 2020-04-01
RU2022101599A (en) 2022-02-25
WO2017151680A2 (en) 2017-09-08
JP7546345B2 (en) 2024-09-06
SG11201807334SA (en) 2018-09-27
MX2022010682A (en) 2022-09-23
MX2018010388A (en) 2019-03-06
KR20250024857A (en) 2025-02-19
RU2765308C2 (en) 2022-01-28
RU2018134197A3 (en) 2021-07-02
BR112018067903A2 (en) 2019-04-16
PH12018501843A1 (en) 2019-05-15
CA3016037A1 (en) 2017-09-08
CN109415766A (en) 2019-03-01
EP3423597A2 (en) 2019-01-09
AU2022268325A1 (en) 2022-12-15
AU2022268325B2 (en) 2024-09-19
WO2017151680A3 (en) 2017-10-12
JP2022095695A (en) 2022-06-28
JP2019512480A (en) 2019-05-16
AU2017227608B2 (en) 2023-06-01

Similar Documents

Publication Publication Date Title
EP3423597A4 (en) METHODS, COMPOSITIONS AND DEVICES FOR STORING INFORMATION
EP3532639A4 (en) METHODS, COMPOSITIONS AND DEVICES FOR INFORMATION STORAGE
EP3507936A4 (en) SECURE STORAGE AUDIT AUDIT SYSTEM
EP3451973A4 (en) ANNULOPLASTY PROCEDURES, DEVICES AND RELATED METHODS
EP3600318A4 (en) METHODS FOR USING EHMT2 INHIBITORS
EP3485068A4 (en) ELECTROCHEMICAL METHODS, DEVICES AND COMPOSITIONS
EP3480211A4 (en) MOLECULAR CONJUGATE CONTAINING HANP-FC
EA201790380A1 (en) MK2 INHIBITORS AND THEIR APPLICATIONS
EP3415373A4 (en) INFORMATION PROVIDING DEVICE
EP3404697A4 (en) SEMICONDUCTOR STORAGE DEVICE
EP3408422A4 (en) BINDER COMPOSITIONS CONTAINING TUNGSTEN TETRABORIDE AND ASSOCIATED ABRASION METHODS
EP3375796A4 (en) COPOLYMER AND COMPOSITION CONTAINING SAME
EP3585281A4 (en) ATHEREECTOMY DEVICES AND METHODS
EP3439412A4 (en) PREAMBLE CONFIGURATION AND SENDING METHODS, AND DEVICES THEREOF
EP3486910A4 (en) STORAGE DEVICE
EP3496768A4 (en) ANTIMICROBIAL COMPOSITIONS AND RELATED METHODS OF USE.
EP3432228A4 (en) DEVICE FOR MAINTAINING EXTENSIBILITY
EP3412344A4 (en) EXTINGUISHING AGENT COMPOSITION
EP3457869A4 (en) STORAGE AND DISTRIBUTION SYSTEM
EP3363352A4 (en) DEVICE FOR PRESENTING USEFUL INFORMATION
EP3507167C0 (en) MOBILE STORAGE UNIT
MA45047A (en) METHODS FOR USING FASN INHIBITORS
EP3476213A4 (en) ABSORBENT ARTICLE FOR PETS
MA44972A (en) CFTR MODULATOR IDENTIFICATION PROCESSES
MX374654B (en) COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T.

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20180927

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12P 19/34 20060101ALI20191029BHEP

Ipc: C12Q 1/68 20180101AFI20191029BHEP

Ipc: G06N 3/12 20060101ALN20191029BHEP

Ipc: C07H 21/04 20060101ALI20191029BHEP

Ipc: G11C 13/00 20060101ALN20191029BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20200205

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/68 20180101AFI20200130BHEP

Ipc: C12P 19/34 20060101ALI20200130BHEP

Ipc: G06N 3/12 20060101ALN20200130BHEP

Ipc: G11C 13/00 20060101ALN20200130BHEP

Ipc: C07H 21/04 20060101ALI20200130BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20230704