EP2764919A1 - Dispositif d'analyse d'un liquide de test - Google Patents
Dispositif d'analyse d'un liquide de test Download PDFInfo
- Publication number
- EP2764919A1 EP2764919A1 EP13154869.5A EP13154869A EP2764919A1 EP 2764919 A1 EP2764919 A1 EP 2764919A1 EP 13154869 A EP13154869 A EP 13154869A EP 2764919 A1 EP2764919 A1 EP 2764919A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- chamber
- housing
- treatment
- input
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 84
- 239000012530 fluid Substances 0.000 title claims description 34
- 238000004458 analytical method Methods 0.000 claims abstract description 57
- 238000012545 processing Methods 0.000 claims abstract description 47
- 239000007788 liquid Substances 0.000 claims abstract description 33
- 238000002386 leaching Methods 0.000 claims description 17
- 238000011049 filling Methods 0.000 claims description 16
- 238000007789 sealing Methods 0.000 claims description 9
- 239000000126 substance Substances 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 6
- 210000003296 saliva Anatomy 0.000 description 4
- 238000010276 construction Methods 0.000 description 3
- 230000003750 conditioning effect Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
Definitions
- the invention relates to a device for analyzing a test fluid according to the preamble of claim 1.
- Such devices can be used, for example, for the analysis of saliva or urine of a subject.
- other liquids are analyzed or a sample substance to be analyzed, for example in the form of a solid, is first mixed or dissolved in a so-called leaching solution and the test liquid obtained is subsequently analyzed.
- the analysis can be used, for example, for the detection of drugs, explosives or other substances, such as traces of nuts.
- test fluid which can be analyzed.
- the mixture is achieved in such a way that a sample collector with which the sample substance can be taken up is washed out in the washing-out liquid.
- the test liquid is usually processed.
- the test fluid can be brought into contact with a reaction partner, for example in the form of gold conjugate.
- the treatment is also referred to as a so-called incubation.
- the thus prepared test fluid is passed to an analysis element containing, for example, a test strip, also referred to as a so-called lateral flow assay.
- the test strip is loaded at one end with the test fluid, which then flows through the test strip and collects in a collection pad at the opposite end of the test strip.
- the test strip may have a nitrocellulose membrane on which test lines and control lines are arranged, which react with the test liquid and on which a reaction and thus the analysis result are readable.
- the analysis result can be read and processed for example by means of a special electronic evaluation device.
- the device has an input chamber, a processing chamber and an analysis element with a test strip.
- the device also has a housing with a housing interior, in which a treatment element at least partially limiting conditioning element and an input chamber at least partially limiting input element are arranged.
- the test strip is arranged in the housing so that it is at least partially visible from the outside.
- the test liquid in the form of saliva of a subject can be picked up with a sample collector and introduced into the inlet chamber.
- the sample collector is expressed so that test liquid enters the input chamber. By pushing the sample collector to the bottom of the input chamber, it is moved in the direction of the processing chamber below it.
- the input chamber is displaced until the bottom of the input chamber ruptures, thus flowing an undefined amount of the test fluid from the input chamber into the processing chamber.
- a slide arranged between the processing chamber and the test strip is opened so that the conditioned test liquid can reach one end of the test strip.
- the analysis result on the test strip can then be read as described above.
- An opening of the input element is arranged perpendicular to the test strip.
- the device has a processing chamber in the form of a mixing chamber and an analysis element with a test strip.
- test liquid is filled from a separate washout in the processing chamber, from which it is passed to the test strip after preparation.
- To fill a certain amount of test fluid into the processing chamber it has a level mark up to which a user of the device is to fill test fluid. It is not possible to monitor or check the amount of test fluid actually filled in.
- the device according to the invention for analyzing a test fluid has an inlet chamber, a treatment chamber and an analysis element.
- the device also has a housing with a housing interior, in which a treatment element at least partially limiting conditioning element and an input chamber at least partially limiting input element are arranged.
- the test strip is arranged in the housing so that it is at least partially visible from the outside.
- the input chamber is intended to receive the test fluid. Test fluid can be transferred from the input chamber to the analysis element via the treatment chamber.
- the housing interior is cylindrical and the treatment element is rotatable relative to the input element and the housing.
- This makes it possible to make the housing very compact, in particular with a cylindrical or cuboid outer contour.
- the device is also easy and reliable to handle, since the various necessary for the analysis positions of the individual components to each other by a simple rotation of the processing element relative to the input member and the housing are adjustable.
- the analysis element has one or more test strips which are arranged in the axial direction of the housing.
- the treatment element and the input element each have a mainly hollow cylindrical basic shape and the input element is disposed within the treatment element.
- the housing, the treatment element and the input element are designed and arranged so that in an initial position, the input chamber and the processing chamber are separated from each other.
- a filling position is adjustable, in which the treatment chamber is connected to the input chamber and separated from the analysis element.
- an analysis position is adjustable, in which the treatment chamber is connected to the analysis element. This allows a particularly compact design of the device and a particularly simple handling.
- the rotation of the processing element from the starting position into the filling position and further into the analysis position takes place in particular in only one direction of rotation. It is possible that for safe adjustment of the various positions detents between the housing and processing element are provided, which fix the processing element in the individual positions, but can be suppressed.
- the processing element may have one or more recesses and the housing correspondingly positioned elevations.
- the detents can also be provided between the housing and a component connected to the treatment element, with which, for example, a force for rotating the treatment element can be introduced.
- the input chamber is separated from the analysis element in the analysis position. This prevents further test liquid from flowing during or after preparation and thus influencing the analysis result.
- the input element and the housing are rotatably connected to each other. This is necessary to adjust the various positions only a rotation of the treatment element. This allows a simple construction and easy handling of the device.
- a treatment position is adjustable, in which the processing chamber is separated from the input chamber and the analysis element. This prevents further test liquid from flowing during or after preparation and thus influencing the analysis result. This makes very precise analyzes possible.
- the input chamber has at least one passage in the direction of the treatment element and the treatment chamber is designed as a continuous recess in the treatment element. This allows a particularly simple and inexpensive construction of the device.
- the recess of the treatment element By rotating the treatment element from the starting position relative to the input element and thus opposite the input chamber, the recess of the treatment element can be positioned so that it overlaps with said passage of the input chamber and is thus connected to the input chamber. This is the case in the filling phase, in which then fills the recess and thus the processing chamber with test liquid from the input chamber.
- the inlet chamber and the treatment chamber are designed so that the treatment chamber is completely filled. Since the recess has a defined size, the treatment chamber contains a defined amount of test fluid after filling. This ensures a defined preparation of the test fluid and thus an accurate analysis result.
- the analysis element has more than one test strip, in particular for each test strip a separate passage of the input chamber and a separate recess of the treatment element and thus a separate processing chamber are provided.
- This makes it possible in an advantageous manner to be able to process the test liquid differently in the different processing chambers.
- For this purpose for example, be contained in the different test chambers different reactants.
- the input member After filling, the input member is further rotated until the analysis position is reached, in which the recess of the input member does not overlap with the passage of the input chamber.
- the device has a plug, which can be inserted into an opening of the treatment element.
- a force for rotating the treatment element can be introduced via the plug.
- the input chamber can be closed in an initial state of the device and so contamination of the input chamber, which could falsify the analysis result, can be prevented.
- an initial state of the device should be understood to be an unused state, that is to say the state before the start of an analysis of a sample substance or a test fluid.
- the plug can additionally be used to adjust the various positions of the treatment element necessary for the analysis of the test fluid.
- the stopper and the said opening of the treatment element have corresponding cross sections in the form of a so-called equal dia.
- the plug and the opening are made conical, in particular in the axial direction. When inserting, this causes the stopper to self-center in the opening. Thus, the plug can be easily inserted into the opening and it is still a good power transmission from the plug to the treatment element guaranteed.
- An equal thickness is a closed line that always touches all four sides in any position within a suitable square.
- the cross section may also be referred to as a so-called harmonic polygon profile with a so-called continuous P3 shape curve.
- the plug has a sample collector. Thus, only a few parts are necessary for the device.
- the plug has a storage cylinder.
- the storage cylinder contains in the initial state of the device leaching.
- the leaching liquid can only be filled in the input chamber when it is really needed, without providing for the leaching a separate container. For example, if the plug was removed with the sample collector to take a sample, there is still no leaching in the input chamber, which could leak out unintentionally.
- the plug has a base body with a mainly cylindrical inner contour and a relative to the main body immovable inner part.
- the inner part dives when inserting the storage cylinder into the main body in the storage cylinder and closes the storage cylinder in a start position. It also has a connecting line, which is connected after leaving the starting position with the storage cylinder and over which is inserted in the plug leaching fluid into the input chamber can be conducted. This allows in a very simple manner, the feeding of the leaching into the input chamber. This only needs the supply cylinder in the direction Input chamber are pressed and thus pushed onto the inner part.
- the inner part and the base body of the plug can consist of either one or more parts, in particular two parts.
- the storage cylinder has an inner circumferential sealing lip on which the inner part of the base body is present in the starting position and thus concludes the storage cylinder.
- the connecting line has a radial section and an axial section which are designed such that after the radial section has at least partially passed over the sealing lip of the storage cylinder, leaching fluid can be pressed out of the storage chamber via the radial section into the axial section. This allows a particularly simple construction of the plug.
- Said radial section does not have to be exactly radial; it is sufficient if it has a radially inward component from one edge of the inner part, so that leaching fluid can flow inward from the edge of the inner part to the axial section.
- the axial section also does not have to be exactly aligned axially. It is sufficient if it is designed so that it can guide leaching fluid from the radial section in the axial direction in the direction of the inlet chamber.
- the axial section runs in particular at least partially in a shaft of the sample collector.
- the housing has a first recess, through which markings on the treatment element, which indicate a current position of the treatment element, are visible.
- markings on the treatment element which indicate a current position of the treatment element.
- the analysis element has at least one or more, in particular two test strips, which is arranged in the housing and is visible through a second recess in the housing.
- the individual parts of the device may for example be made of polyethylene or polypropylene and in particular be produced by means of an injection molding process.
- a device 10 for analyzing a test fluid has a housing 11 which has a basically cylindrical outer contour.
- a plug 12 is attached, which has a in Fig. 1 not visible opening of the housing 11 closes.
- the plug 12 can be rotated relative to the housing 11, whereby different phases of the analysis, in which different components of the device must assume certain positions, can be adjusted.
- Fig. 2 the plug 12 is removed from the housing 11.
- the plug 12 has a sample collector 13 which, in the inserted state of the plug 12 in accordance Fig. 1 is disposed within the housing 11.
- the sample collector 13 has a shaft 14 and a receiving tip 15.
- the shaft 14 of the sample collector 13 also has a sealing washer 46, which for sealing a in Fig. 2 not shown inlet chamber is used.
- the housing 11 has a cylindrical housing interior 16, in which a mainly hollow-cylindrical processing element 17 is arranged.
- the processing element 17 partially limits two treatment chambers, but only in the FIGS. 5, 6 and 7 are shown in more detail.
- a likewise mainly hollow-cylindrical input element 18 is arranged, which forms an input chamber 19 in its interior.
- the input element 18 and thus the input chamber 19 have two diametrically opposite passages 20, 21 in the direction of treatment element 17.
- a connection between the inlet chamber 19 and the treatment chambers can be established via the two passages 20, 21.
- the stopper 12 closes on the one hand with an inner part 22, the input chamber 19 and is used on the other with an outer part 23 in an opening 42 of the treatment element 17.
- the outer part 23 of the plug 12 and the opening 42 of the treatment element 17 have no circular cross-section, but the contour of a DC, in particular a so-called continuous P3 shape curve, which is not clearly seen in the figures.
- the outer part 23 of the plug 12 and the opening 42 are also made conical only a few degrees in the direction of receiving tip 15. By said contour can be exerted or introduced by the plug 12, a force to rotate with respect to the input member 18 and the housing 11 1 on the processing element 17.
- the processing element 17 by means of the plug 12 relative to the input member 18 and the housing 11 are rotated.
- the input element 18 and the housing 11 are rotatably connected to each other, which is realized via a snap connection between input element 18 housing 11, not shown.
- the plug 12 has a storage cylinder 25 which contains a leaching liquid in an initial state of the device 10.
- the storage cylinder 25 is inserted in the initial state of the device only a piece into a base body 26 of the plug 12, which corresponds to a starting position of the storage cylinder 25.
- the main body 26 has a mainly cylindrical inner contour, which corresponds to an outer contour of the storage cylinder 25.
- Within the base body 26, a stationary relative to the base body 26 inner part 27 is arranged, which is arranged within the storage cylinder 25.
- the inner part 27 abuts in the starting position of the storage cylinder 25 at an inner peripheral sealing lip 28 of the storage cylinder 25, whereby the storage cylinder 25 is sealed and no washout liquid can escape from the storage cylinder 25.
- the leaching liquid from the storage cylinder 25 must be brought into the input chamber 19.
- the storage cylinder 25 is pressed starting from its starting position in the direction of the housing 11, whereby a radial section 29 of a connecting line 30 via the sealing lip 28 and then to you are pushed past.
- This leaching fluid from the storage cylinder 25 can flow into the radial section 29 of the connecting line 30, which extends from the radially outside to the inside.
- the radial section 29 of the connecting line 30 is connected to an axial section 31 of the connecting line 30, which extends within the shaft 14 of the sample collector 13.
- the axial section 31 of the connecting line 30 extends up to an outlet opening 32, which is seen from the storage cylinder 25 below the sealing disc 46.
- 12 can be brought from the storage cylinder 25 in the input chamber 19 by inserting or pushing the stock cylinder 25 into the main body 26 of the plug 12 leaching.
- the receiving tip 15 of the sample collector 13 is immersed in the leaching liquid located in the inlet chamber 19.
- the recorded sample substance is washed out.
- the mixture of sample substance and leachate gives a test liquid, which can then be analyzed.
- test liquid For the further analysis of the test liquid, first a certain amount of the test liquid has to be brought into one or more processing chambers and from there on to an analysis element.
- FIGS. 5, 6 and 7 The necessary steps will be taken by hand FIGS. 5, 6 and 7 described.
- diametrically opposite two test strips 35, 36 are arranged as part of an analysis element.
- a flow direction of the test strips is parallel to the shaft 14 of the sample collector 13, ie in the axial direction.
- the processing element 17 is arranged within the housing 11.
- the treatment element 17 has two diametrically opposite recesses, which form treatment chambers 33, 34.
- the input element 18 is arranged with its already described passages 20, 21.
- the individual, in the FIGS. 5, 6 and 7 shown positions of the device 10 differ only in the position of the processing chambers 33, 34 to the passages 20, 21 and to the test strips 35, 36th
- the in Fig. 6 set filling position shown.
- the treatment chambers 33, 34 overlap each with a passage 20, 21 of the inlet chamber 19, but not with the test strips 35, 36.
- the treatment chambers 33, 34 are filled with test liquid.
- the device 10 should be held so that the plug 12 is located at the top and the shaft 14 of the sample collector is aligned as vertically as possible upwards. Then it is ensured that due to gravity, the treatment chambers 33, 34 completely filled with test liquid and thus each a defined amount of test liquid from the input chamber 19 into the processing chambers 33, 34 is filled.
- the processing chambers 33, 34 is in each case a reaction partner, for example in the form of gold conjugate, which processes the test liquid.
- the treatment element 17 is rotated further into a processing position, not shown.
- the treatment chambers 33, 34 have neither a cover with the passages 20, 21 of the input chamber 19, nor with the test strips 35, 36 as in the starting position.
- the treatment takes a fixed period of, for example, 4 minutes, which must be awaited.
- the filling position is fixed for a certain time. It is sufficient if the filling position is run over during rotation of the processing element 17 from the starting position to the processing position.
- the processed test liquid from the processing chambers 33, 34 must be brought to one end of the test strips 35, 36.
- the processing element 17 from the processing position in the in Fig. 7 rotated analysis position shown.
- the analysis position the treatment chambers 33, 34 have an overlap with the test strips 35, 36, so that processed test liquid can reach the test strips 35, 36.
- the test fluid then flows through the test strips as described above, so that after a specified waiting time of, for example, 8 minutes, the analysis result can be read on the test strip.
- the treatment chambers 33, 34 have no overlap with the passages 20, 21 of the inlet chamber 19.
- the housing 11 has a first recess 37, through which markings 38 on the processing element 17, which indicate the current position processing element 17, are visible.
- the display of the position may also consist of the fact that the duration of a waiting time already described above is displayed.
- the housing 11 has parallel to the first recess 37 and offset by 90 ° to a second recess 39, through which the test strip 35 of the analysis element visible and thus the analysis result is read.
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13154869.5A EP2764919A1 (fr) | 2013-02-12 | 2013-02-12 | Dispositif d'analyse d'un liquide de test |
| EP14703402.9A EP2928609B1 (fr) | 2013-02-12 | 2014-02-10 | Dispositif d'analyse d'un liquide de test |
| US14/766,988 US9387474B2 (en) | 2013-02-12 | 2014-02-10 | Apparatus for analyzing a test liquid |
| PCT/EP2014/052563 WO2014124905A1 (fr) | 2013-02-12 | 2014-02-10 | Appareil permettant d'analyser un liquide d'essai |
| CN201480008520.5A CN105102128B (zh) | 2013-02-12 | 2014-02-10 | 用于分析测试液体的设备 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13154869.5A EP2764919A1 (fr) | 2013-02-12 | 2013-02-12 | Dispositif d'analyse d'un liquide de test |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP2764919A1 true EP2764919A1 (fr) | 2014-08-13 |
Family
ID=47748411
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP13154869.5A Withdrawn EP2764919A1 (fr) | 2013-02-12 | 2013-02-12 | Dispositif d'analyse d'un liquide de test |
| EP14703402.9A Active EP2928609B1 (fr) | 2013-02-12 | 2014-02-10 | Dispositif d'analyse d'un liquide de test |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP14703402.9A Active EP2928609B1 (fr) | 2013-02-12 | 2014-02-10 | Dispositif d'analyse d'un liquide de test |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9387474B2 (fr) |
| EP (2) | EP2764919A1 (fr) |
| CN (1) | CN105102128B (fr) |
| WO (1) | WO2014124905A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10980520B2 (en) | 2015-10-19 | 2021-04-20 | Green Panther, LLC | Urine sampling vessel |
| KR102509048B1 (ko) * | 2016-04-26 | 2023-03-10 | 에스케이하이닉스 주식회사 | 반도체 패키지 |
| GB201700340D0 (en) | 2017-01-09 | 2017-02-22 | Gsg Tech Ltd | fluid manipulation cartridge and controller mechanism |
| WO2025212014A1 (fr) * | 2024-04-03 | 2025-10-09 | Apac Security Pty Ltd. | Systèmes et procédés pour l'analyse diagnostique d'un analyte dans un échantillon |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277646B1 (en) * | 1997-05-05 | 2001-08-21 | Dade Behring Inc. | Fluid specimen collecting and testing apparatus |
| US20050084842A1 (en) * | 2003-10-20 | 2005-04-21 | O'connor Amanda L. | Diagnostic test device and method of using same |
| US20060292034A1 (en) | 2005-06-28 | 2006-12-28 | American Bio Medica Corporation | Saliva sample testing device |
| WO2009036168A2 (fr) * | 2007-09-11 | 2009-03-19 | University Of Florida Research Foundation, Inc. | Dispositifs et procédés de prélèvement et de détection de substances |
| DE202008017883U1 (de) | 2008-03-25 | 2010-10-21 | Matallana-Kielmann, Michael | Vorrichtung und Anordnung für einen Teststreifenhalter |
| WO2011018658A1 (fr) * | 2009-08-10 | 2011-02-17 | Forensic Science Service Limited | Perfectionnements apportés à la manipulation d'échantillons et s'y rapportant |
-
2013
- 2013-02-12 EP EP13154869.5A patent/EP2764919A1/fr not_active Withdrawn
-
2014
- 2014-02-10 WO PCT/EP2014/052563 patent/WO2014124905A1/fr not_active Ceased
- 2014-02-10 EP EP14703402.9A patent/EP2928609B1/fr active Active
- 2014-02-10 CN CN201480008520.5A patent/CN105102128B/zh not_active Expired - Fee Related
- 2014-02-10 US US14/766,988 patent/US9387474B2/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277646B1 (en) * | 1997-05-05 | 2001-08-21 | Dade Behring Inc. | Fluid specimen collecting and testing apparatus |
| US20050084842A1 (en) * | 2003-10-20 | 2005-04-21 | O'connor Amanda L. | Diagnostic test device and method of using same |
| US20060292034A1 (en) | 2005-06-28 | 2006-12-28 | American Bio Medica Corporation | Saliva sample testing device |
| WO2009036168A2 (fr) * | 2007-09-11 | 2009-03-19 | University Of Florida Research Foundation, Inc. | Dispositifs et procédés de prélèvement et de détection de substances |
| DE202008017883U1 (de) | 2008-03-25 | 2010-10-21 | Matallana-Kielmann, Michael | Vorrichtung und Anordnung für einen Teststreifenhalter |
| WO2011018658A1 (fr) * | 2009-08-10 | 2011-02-17 | Forensic Science Service Limited | Perfectionnements apportés à la manipulation d'échantillons et s'y rapportant |
Also Published As
| Publication number | Publication date |
|---|---|
| US20160001286A1 (en) | 2016-01-07 |
| US9387474B2 (en) | 2016-07-12 |
| EP2928609A1 (fr) | 2015-10-14 |
| CN105102128A (zh) | 2015-11-25 |
| EP2928609B1 (fr) | 2019-04-24 |
| CN105102128B (zh) | 2017-08-29 |
| WO2014124905A1 (fr) | 2014-08-21 |
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