EP2431475A3 - Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren - Google Patents
Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren Download PDFInfo
- Publication number
- EP2431475A3 EP2431475A3 EP20110193920 EP11193920A EP2431475A3 EP 2431475 A3 EP2431475 A3 EP 2431475A3 EP 20110193920 EP20110193920 EP 20110193920 EP 11193920 A EP11193920 A EP 11193920A EP 2431475 A3 EP2431475 A3 EP 2431475A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- pha
- polyhydroxyalkanoate
- glycolic acid
- polymer
- hydroxyacid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 title abstract 5
- 239000000178 monomer Substances 0.000 title 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 6
- 239000005014 poly(hydroxyalkanoate) Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 229920000903 polyhydroxyalkanoate Polymers 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31507—Of polycarbonate
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polyesters Or Polycarbonates (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37958302P | 2002-05-10 | 2002-05-10 | |
| EP20030808364 EP1654373B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
| PCT/US2003/014573 WO2004038030A2 (en) | 2002-05-10 | 2003-05-07 | Bioabsorbable polymer containing 2-hdroxyacid monomers |
Related Parent Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03808364.8 Division | 2003-05-07 | ||
| EP20030808364 Division EP1654373B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
| EP20030808364 Division-Into EP1654373B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2431475A2 EP2431475A2 (de) | 2012-03-21 |
| EP2431475A3 true EP2431475A3 (de) | 2012-06-20 |
| EP2431475B1 EP2431475B1 (de) | 2019-07-10 |
Family
ID=32176356
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP11193920.3A Expired - Lifetime EP2431475B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
| EP20030808364 Expired - Lifetime EP1654373B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20030808364 Expired - Lifetime EP1654373B1 (de) | 2002-05-10 | 2003-05-07 | Bioabsorbierbares polymer mit 2-hydroxysäure-monomeren |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8039237B2 (de) |
| EP (2) | EP2431475B1 (de) |
| JP (2) | JP4780961B2 (de) |
| AU (1) | AU2003301617A1 (de) |
| ES (2) | ES2741964T3 (de) |
| WO (1) | WO2004038030A2 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1105514B1 (de) | 1998-08-04 | 2008-02-06 | Metabolix, Inc. | Herstellung von polyhydroxyalkanoaten aus polyolen |
| EP1163019B1 (de) | 1999-03-25 | 2007-10-24 | Metabolix, Inc. | Medizinische vorrichtungen und verwendungen von polyhydroxyalkanoatpolymeren |
| EP1334181B1 (de) * | 2000-11-17 | 2010-03-17 | Metabolix, Inc. | Herstellung von polyhydroxyalkanoaten mittlerer kettenlänge aus fettsäure-biosynthesewegen |
| ES2819189T3 (es) | 2003-05-08 | 2021-04-15 | Tepha Inc | Tejidos y fibras médicos de polihidroxialcanoato |
| EP2221069B1 (de) | 2004-08-03 | 2012-05-09 | Tepha, Inc. | Polyhydroxyalkanoate Nähte die sich nicht aufrollen |
| WO2006069282A2 (en) * | 2004-12-22 | 2006-06-29 | California Institute Of Technology | Degradable p0lymers and methods of preparation thereof |
| US8016883B2 (en) * | 2006-02-07 | 2011-09-13 | Tepha, Inc. | Methods and devices for rotator cuff repair |
| CA2640750C (en) * | 2006-02-07 | 2013-12-17 | Tepha, Inc. | Polymeric, degradable drug-eluting stents and coatings comprising copolymers or homopolymers of 4-hydroxybutyrate |
| US9592325B2 (en) * | 2006-02-07 | 2017-03-14 | Tepha, Inc. | Polymeric, degradable drug-eluting stents and coatings |
| US8979921B2 (en) * | 2006-02-07 | 2015-03-17 | Tepha, Inc. | Polymeric, degradable drug-eluting stents and coatings |
| US9089627B2 (en) | 2006-07-11 | 2015-07-28 | Abbott Cardiovascular Systems Inc. | Stent fabricated from polymer composite toughened by a dispersed phase |
| US7794495B2 (en) * | 2006-07-17 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Controlled degradation of stents |
| US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
| US20100210017A1 (en) * | 2007-01-12 | 2010-08-19 | Gill Ryan T | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms |
| JP2010517638A (ja) * | 2007-02-02 | 2010-05-27 | トアニエ, インコーポレイテッド | 腱および靱帯を修復するシステムおよび方法 |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| EP2225373A4 (de) * | 2007-12-13 | 2014-04-30 | Glycos Biotechnologies Inc | Mikrobielle umwandlung von ölen und fettsäuren in chemikalien von hohem wert |
| EP2231913B1 (de) * | 2007-12-19 | 2013-01-23 | Tepha, Inc. | Medizinische vorrichtungen mit schmelzgeblasenen vliesstoffen aus poly-r-hydroxybutyrat und copolymeren |
| EP2313491A4 (de) * | 2008-07-08 | 2011-12-07 | Opx Biotechnologies Inc | Verfahren, zusammensetzungen und systeme für die biosynthetische bioproduktion von 1,4-butandiol |
| WO2010003463A1 (en) * | 2008-07-11 | 2010-01-14 | Metabolic Explorer | Method for polymerising glycolic acid with microorganisms |
| KR101085960B1 (ko) | 2009-04-08 | 2011-11-22 | 주식회사 엘지화학 | 락테이트글라이콜레이트 공중합체 또는 락테이트글라이콜레이트하이드록시알카노에이트 공중합체 생성능을 가지는 세포 또는 식물을 이용한 락테이트글라이콜레이트 공중합체 또는 락테이트글라이콜레이트하이드록시알카노에이트 공중합체의 제조방법 |
| AU2010298004B2 (en) | 2009-09-27 | 2016-02-25 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| EP3639861B1 (de) | 2010-03-26 | 2022-04-20 | Tepha, Inc. | Beschichtungen für die herstellung und anwendung von medizinischen polyhydroxyalkanoatvorrichtungen |
| CA2802212C (en) | 2010-06-15 | 2015-03-24 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers |
| US9511169B2 (en) | 2010-06-15 | 2016-12-06 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties |
| WO2012002572A1 (ja) * | 2010-06-30 | 2012-01-05 | 日本水産株式会社 | 有用物質の製造方法 |
| WO2012064526A1 (en) | 2010-11-09 | 2012-05-18 | Tepha, Inc. | Drug eluting cochlear implants |
| WO2012075051A1 (en) | 2010-11-29 | 2012-06-07 | Micromidas, Inc. | Pha-producing bacteria |
| US9370482B1 (en) | 2011-09-09 | 2016-06-21 | Harrison Yu | Method of incorporating additives to shaped porous monocomponent biopolymer fibers during fiber orienting step |
| WO2013049161A1 (en) | 2011-09-27 | 2013-04-04 | Tepha, Inc. | Controlled hydrolysis of poly-4-hydroxybutyrate and copolymers |
| CN103890186A (zh) * | 2011-10-05 | 2014-06-25 | 宝洁公司 | 通过高丝氨酸生产丙烯酸酯和其它产品的微生物和方法 |
| ES2546064T3 (es) | 2011-11-22 | 2015-09-18 | Heraeus Medical Gmbh | Esterilización de monómeros polimerizables |
| ES2734126T3 (es) | 2012-05-21 | 2019-12-04 | Tepha Inc | Composiciones biocerámicas reabsorbibles de poli-4-hidroxibutirato y copolímeros |
| MY185155A (en) | 2012-05-31 | 2021-04-30 | Micromidas Inc | Polyhydroxyalkanoate derivatives, preparation and uses thereof |
| KR20150040359A (ko) | 2012-08-10 | 2015-04-14 | 오피엑스 바이오테크놀로지스, 인크. | 지방산 및 지방산 유도된 산물의 생산을 위한 미생물 및 방법 |
| CN104797713A (zh) * | 2012-11-27 | 2015-07-22 | 昭和电工株式会社 | 1,4-丁二醇的制造方法及微生物 |
| ES2751398T3 (es) | 2013-01-15 | 2020-03-31 | Tepha Inc | Implantes para regeneración de tejido blando y tejido duro |
| US10201640B2 (en) | 2013-03-13 | 2019-02-12 | Tepha, Inc. | Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof |
| US20150119601A1 (en) | 2013-03-15 | 2015-04-30 | Opx Biotechnologies, Inc. | Monofunctional mcr + 3-hp dehydrogenase |
| CA2905602A1 (en) | 2013-03-15 | 2014-09-18 | Sarah M. Hoyt | Flash evaporation for product purification and recovery |
| JP6603658B2 (ja) | 2013-07-19 | 2019-11-06 | カーギル インコーポレイテッド | 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法 |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| US10689498B2 (en) | 2013-08-20 | 2020-06-23 | Tepha, Inc. | Closed cell foams including poly-4-hydroxybutyrate and copolymers thereof |
| US9687585B2 (en) | 2013-08-20 | 2017-06-27 | Tepha, Inc. | Thermoformed poly-4-hydroxybutyrate medical implants |
| US9302029B2 (en) | 2013-10-31 | 2016-04-05 | Tepha, Inc. | Pultrusion of poly-4-hydroxybutyrate and copolymers thereof |
| WO2015069556A1 (en) | 2013-11-05 | 2015-05-14 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| CA2933746C (en) | 2013-12-26 | 2018-12-04 | Tepha, Inc. | Medical implants including laminates of poly-4-hydroxybutyrate and copolymers thereof |
| WO2015143000A1 (en) | 2014-03-18 | 2015-09-24 | Tepha, Inc. | Micro-fiber webs of poly-4-hydroxybutyrate and copolymers thereof produced by centrifugal spinning |
| US10335257B2 (en) | 2014-04-30 | 2019-07-02 | Tepha, Inc. | Three-dimensional resorbable implants for tissue reinforcement and hernia repair |
| ES2674807T3 (es) | 2014-05-16 | 2018-07-04 | Tepha, Inc. | Dispositivos médicos que contienen materiales no tejidos hilados en seco de poli-4-hidroxibutirato y copolímeros con propiedades anisótropas |
| US10500303B2 (en) | 2014-08-15 | 2019-12-10 | Tepha, Inc. | Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof |
| ES2661648T3 (es) | 2014-08-20 | 2018-04-02 | Tepha, Inc. | Implantes médicos de poli-4-hidroxibutirato termoformados |
| EP2993228B1 (de) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Herstellung von fettsäureestern |
| US10525172B2 (en) | 2014-09-22 | 2020-01-07 | Tepha, Inc. | Oriented P4HB implants containing antimicrobial agents |
| CA2969429C (en) | 2014-12-11 | 2020-10-27 | Tepha, Inc. | Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof |
| US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| AU2016222831B2 (en) | 2015-02-27 | 2020-11-19 | Championx Usa Inc. | Compositions for enhanced oil recovery |
| WO2017196938A1 (en) | 2016-05-13 | 2017-11-16 | Ecolab USA, Inc. | Corrosion inhibitor compositions and methods of using same |
| CA3029400A1 (en) | 2016-06-28 | 2018-01-04 | Ecolab Usa Inc. | Composition, method and use for enhanced oil recovery |
| EP3577227A4 (de) | 2017-02-02 | 2020-12-30 | Cargill Inc. | Genetisch veränderte zellen, die c6-c10-fettsäurederivate produzieren |
| ES2935295T3 (es) | 2017-05-25 | 2023-03-03 | Tepha Inc | Formación continua de tubos de poli-4-hidroxibutirato y sus copolímeros |
| US11559604B2 (en) | 2017-08-31 | 2023-01-24 | University Of Westminster | Nerve conduits |
| US10874498B2 (en) | 2017-09-06 | 2020-12-29 | Tepha, Inc. | Calendered surgical meshes comprising polyhydroxyalkanoates |
| WO2019112925A1 (en) | 2017-12-04 | 2019-06-13 | Tepha, Inc. | Vacuum membrane thermoformed poly-4-hydroxybutyrate medical implants |
| EP3802062B1 (de) | 2018-06-11 | 2024-09-18 | Tepha, Inc. | Verfahren zum 3d-drucken von poly-4-hydroxybutyrat |
| EP3873546B1 (de) | 2018-10-29 | 2023-07-12 | Tepha, Inc. | Verfahren zur herstellung von mesh-nahtmaterial aus poly-4-hydroxybutyrat und copolymere davon |
| KR102579087B1 (ko) * | 2020-07-31 | 2023-09-15 | 킴벌리-클라크 월드와이드, 인크. | 자동 생분해성 흡수 용품 |
| JP2024510182A (ja) | 2021-03-11 | 2024-03-06 | テファ, インコーポレイテッド | 乳房再建インプラント |
| WO2023049120A1 (en) | 2021-09-21 | 2023-03-30 | Sun Chemical Corporation | Water-borne heat-sealable barrier coatings |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998051812A2 (en) * | 1997-05-12 | 1998-11-19 | Metabolix, Inc. | Polyhydroxyalkanoates for in vivo applications |
| WO1999032536A1 (en) * | 1997-12-22 | 1999-07-01 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
| WO2000008198A1 (en) * | 1998-08-04 | 2000-02-17 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
| WO2000056376A1 (en) * | 1999-03-25 | 2000-09-28 | Metabolix, Inc. | Medical devices and applications of polyhydroxyalkanoate polymers |
| WO2002008428A2 (en) * | 2000-07-21 | 2002-01-31 | Metabolix, Inc. | Production of polyhydroxyalkanoates from polyols |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3736646A (en) | 1971-10-18 | 1973-06-05 | American Cyanamid Co | Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures |
| US3867190A (en) | 1971-10-18 | 1975-02-18 | American Cyanamid Co | Reducing capillarity of polyglycolic acid sutures |
| EP0145233B2 (de) | 1983-11-23 | 1991-11-06 | Imperial Chemical Industries Plc | Trennungsverfahrenfür ein 3-hydroxybutyrat-Polymer |
| US5245023A (en) | 1987-06-29 | 1993-09-14 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| US5250430A (en) | 1987-06-29 | 1993-10-05 | Massachusetts Institute Of Technology | Polyhydroxyalkanoate polymerase |
| US5229279A (en) | 1987-06-29 | 1993-07-20 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| US5480794A (en) | 1987-06-29 | 1996-01-02 | Massachusetts Institute Of Technology And Metabolix, Inc. | Overproduction and purification of soluble PHA synthase |
| ZA95627B (en) | 1994-01-28 | 1995-10-05 | Procter & Gamble | Biodegradable copolymers and plastic articles comprising biodegradable copolymers |
| FR2719012B1 (fr) | 1994-04-22 | 1996-07-12 | Pomagalski Sa | Pince débrayable d'un véhicule tracté par câble. |
| US5563239A (en) | 1994-11-09 | 1996-10-08 | Eastman Chemical Company | Composition and process for the production of poly(3-hydroxyalkanoates) |
| US5819180A (en) | 1996-07-31 | 1998-10-06 | Ericsson Inc. | Automatic call generator with a mobile telecommunications network based upon mobile subscriber's location |
| US6610764B1 (en) | 1997-05-12 | 2003-08-26 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
| DE69827948T2 (de) * | 1997-07-25 | 2005-12-01 | Metabolix, Inc., Cambridge | Nukleierungsmittel für polyhydroxyalkanoate und andere thermoplastischen polyester, verfahren zu deren herstellung und ihre verwendung |
| EP1334181B1 (de) | 2000-11-17 | 2010-03-17 | Metabolix, Inc. | Herstellung von polyhydroxyalkanoaten mittlerer kettenlänge aus fettsäure-biosynthesewegen |
-
2003
- 2003-05-07 ES ES11193920T patent/ES2741964T3/es not_active Expired - Lifetime
- 2003-05-07 EP EP11193920.3A patent/EP2431475B1/de not_active Expired - Lifetime
- 2003-05-07 WO PCT/US2003/014573 patent/WO2004038030A2/en not_active Ceased
- 2003-05-07 JP JP2004546663A patent/JP4780961B2/ja not_active Expired - Fee Related
- 2003-05-07 EP EP20030808364 patent/EP1654373B1/de not_active Expired - Lifetime
- 2003-05-07 ES ES03808364T patent/ES2395142T3/es not_active Expired - Lifetime
- 2003-05-07 AU AU2003301617A patent/AU2003301617A1/en not_active Abandoned
- 2003-05-07 US US10/434,334 patent/US8039237B2/en not_active Expired - Lifetime
-
2009
- 2009-06-17 JP JP2009144458A patent/JP4975782B2/ja not_active Expired - Fee Related
-
2011
- 2011-09-30 US US13/250,492 patent/US8703449B2/en not_active Expired - Lifetime
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998051812A2 (en) * | 1997-05-12 | 1998-11-19 | Metabolix, Inc. | Polyhydroxyalkanoates for in vivo applications |
| WO1999032536A1 (en) * | 1997-12-22 | 1999-07-01 | Metabolix, Inc. | Polyhydroxyalkanoate compositions having controlled degradation rates |
| WO2000008198A1 (en) * | 1998-08-04 | 2000-02-17 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
| US6329183B1 (en) * | 1998-08-04 | 2001-12-11 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
| WO2000056376A1 (en) * | 1999-03-25 | 2000-09-28 | Metabolix, Inc. | Medical devices and applications of polyhydroxyalkanoate polymers |
| WO2002008428A2 (en) * | 2000-07-21 | 2002-01-31 | Metabolix, Inc. | Production of polyhydroxyalkanoates from polyols |
Non-Patent Citations (2)
| Title |
|---|
| KHELIFA N ET AL: "Synthesis of 2-hydroxy acid from 2-amino acid by Clostridium butyricum", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 8, no. 23, 1 December 1998 (1998-12-01), pages 3429 - 3434, XP004143771, ISSN: 0960-894X * |
| STEINBUECHEL A ET AL: "DIVERSITY OF BACTERIAL POLYHYDROXYALKANOIC ACIDS", FEMS MICROBIOLOGY LETTERS, BLACKWELL PUBLISHING, AMSTERDAM, NL, vol. 128, no. 3, 15 May 1995 (1995-05-15), pages 219 - 228, XP000828495, ISSN: 0378-1097 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003301617A8 (en) | 2004-05-13 |
| US8703449B2 (en) | 2014-04-22 |
| US20030211131A1 (en) | 2003-11-13 |
| JP2006501858A (ja) | 2006-01-19 |
| ES2741964T3 (es) | 2020-02-12 |
| EP1654373A4 (de) | 2009-10-21 |
| JP4780961B2 (ja) | 2011-09-28 |
| AU2003301617A1 (en) | 2004-05-13 |
| WO2004038030A2 (en) | 2004-05-06 |
| WO2004038030A3 (en) | 2006-10-05 |
| EP1654373A2 (de) | 2006-05-10 |
| US8039237B2 (en) | 2011-10-18 |
| US20120021471A1 (en) | 2012-01-26 |
| EP2431475B1 (de) | 2019-07-10 |
| JP4975782B2 (ja) | 2012-07-11 |
| EP2431475A2 (de) | 2012-03-21 |
| EP1654373B1 (de) | 2012-08-15 |
| JP2009261398A (ja) | 2009-11-12 |
| ES2395142T3 (es) | 2013-02-08 |
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