[go: up one dir, main page]

EP1761166A4 - Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif - Google Patents

Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif

Info

Publication number
EP1761166A4
EP1761166A4 EP05753778A EP05753778A EP1761166A4 EP 1761166 A4 EP1761166 A4 EP 1761166A4 EP 05753778 A EP05753778 A EP 05753778A EP 05753778 A EP05753778 A EP 05753778A EP 1761166 A4 EP1761166 A4 EP 1761166A4
Authority
EP
European Patent Office
Prior art keywords
lipopolysaccharide
diagnosis
condensation
gram negative
negative pneumonia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05753778A
Other languages
German (de)
English (en)
Other versions
EP1761166A2 (fr
Inventor
Jeffrey A Kline
Jackeline Hernandez
John Albert Watts Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charlotte Mecklenburg Hospital
Original Assignee
Charlotte Mecklenburg Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charlotte Mecklenburg Hospital filed Critical Charlotte Mecklenburg Hospital
Publication of EP1761166A2 publication Critical patent/EP1761166A2/fr
Publication of EP1761166A4 publication Critical patent/EP1761166A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0813—Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
EP05753778A 2004-06-07 2005-05-24 Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif Withdrawn EP1761166A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57764104P 2004-06-07 2004-06-07
PCT/US2005/018232 WO2006007180A2 (fr) 2004-06-07 2005-05-24 Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif

Publications (2)

Publication Number Publication Date
EP1761166A2 EP1761166A2 (fr) 2007-03-14
EP1761166A4 true EP1761166A4 (fr) 2009-11-11

Family

ID=35784291

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05753778A Withdrawn EP1761166A4 (fr) 2004-06-07 2005-05-24 Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif

Country Status (8)

Country Link
EP (1) EP1761166A4 (fr)
JP (2) JP4804464B2 (fr)
AU (1) AU2005262701B2 (fr)
BR (1) BRPI0511846A (fr)
CA (1) CA2566804A1 (fr)
IL (5) IL179137A (fr)
MX (1) MXPA06014248A (fr)
WO (1) WO2006007180A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138577A1 (en) 2002-12-20 2004-07-15 Kline Jeffrey A. Disposable hand-held device for collection of exhaled breath condensate
US7828741B2 (en) 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
WO2004073497A2 (fr) 2003-02-14 2004-09-02 The Charlotte-Mecklenburg Hospital Authority Dispositif et procede de collecte de condensat d'exhalation alveolaire
CN101827558B (zh) * 2007-10-02 2013-03-27 安娜-卡林·奥林 呼出的粒子的采集和测量
WO2009149203A1 (fr) * 2008-06-04 2009-12-10 Kci Licensing, Inc. Détection d'infection dans le traitement de plaie à pression réduite
GB201312635D0 (en) * 2013-07-15 2013-08-28 Univ Plymouth Water testing
US10413216B2 (en) * 2016-02-03 2019-09-17 Quintron Instrument Company, Inc. Breath testing apparatus
CN106018362B (zh) * 2016-05-16 2018-06-08 江苏国恒检测有限公司 一种检测苦味酸的测定器
CN108871908B9 (zh) * 2018-09-06 2024-07-26 杭州优思达生物技术股份有限公司 生物样本处理装置
AU2020330524A1 (en) * 2019-08-13 2022-03-03 Respiration Scan Ltd System and method for determining onset and disease progression
KR102543496B1 (ko) * 2019-08-26 2023-06-13 제테오 테크, 인코포레이티드 호기를 이용한 결핵 및 기타 질병의 진단
WO2023038582A2 (fr) * 2021-09-10 2023-03-16 National University Of Singapore Kit de prélèvement de condensat d'air expiré
JP2024536778A (ja) * 2021-09-20 2024-10-08 ヴォスビオ，インコーポレーテッド 生物学的試料の捕捉および処理のためのデバイス、方法およびキット
AU2024283662A1 (en) * 2023-06-05 2025-12-04 Charles River Laboratories, Inc. Recombinant amebocyte clotting factors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001084112A1 (fr) * 2000-05-01 2001-11-08 Respiratory Research, Inc. Procede et dispositif pour recueillir et analyser de l'air exhale

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59383A (en) * 1980-02-14 1983-03-31 Technion Res & Dev Foundation Micromethod for the determination of endotoxins with limulus amebocyte lysate
US4349626A (en) * 1980-10-28 1982-09-14 The Monell Chemical Senses Center Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
SE9704329D0 (sv) * 1997-11-25 1997-11-25 Siemens Elema Ab Gasmätare
JP2002541429A (ja) * 1998-12-18 2002-12-03 ユニバーシティ オブ バージニア パテント ファウンデーション 喘息を監視するための装置と方法
DE60020823T2 (de) * 1999-03-09 2006-05-18 Osmetech Plc, Crewe Diagnostisches verfahren durch analyse von kondensierung aus atmungs gas
US20040234971A1 (en) * 2001-02-01 2004-11-25 Joany Jackman Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001084112A1 (fr) * 2000-05-01 2001-11-08 Respiratory Research, Inc. Procede et dispositif pour recueillir et analyser de l'air exhale

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FLANAGAN P G ET AL: "Diagnosis of Gram negative, ventilator associated pneumonia by assaying endotoxin in bronchial lavage fluid", JOURNAL OF CLINICAL PATHOLOGY, BMJ PUBLISHING GROUP, vol. 54, 1 January 2001 (2001-01-01), pages 107 - 110, XP009122143, ISSN: 0021-9746 *
NAYERI F ET AL: "Exhaled breath condensate and serum levels of hepatocyte growth factor in pneumonia", RESPIRATORY MEDICINE, BAILLIERE TINDALL, LONDON, GB, vol. 96, 10 December 2002 (2002-12-10), pages 115 - 119, XP007909654, ISSN: 0954-6111 *

Also Published As

Publication number Publication date
IL179137A0 (en) 2007-03-08
JP2009186487A (ja) 2009-08-20
MXPA06014248A (es) 2007-06-25
CA2566804A1 (fr) 2006-01-19
IL179137A (en) 2012-07-31
AU2005262701B2 (en) 2011-12-01
WO2006007180A2 (fr) 2006-01-19
IL218188A0 (en) 2012-04-30
EP1761166A2 (fr) 2007-03-14
BRPI0511846A (pt) 2008-01-15
JP4852121B2 (ja) 2012-01-11
AU2005262701A1 (en) 2006-01-19
WO2006007180A3 (fr) 2006-11-30
JP4804464B2 (ja) 2011-11-02
JP2008501976A (ja) 2008-01-24
IL218189A0 (en) 2012-04-30
IL218190A0 (en) 2012-04-30
IL218191A0 (en) 2012-04-30

Similar Documents

Publication Publication Date Title
EP1761166A4 (fr) Utilisation de lipopolysaccharide dans un condensat de respiration exhalee aux fins de diagnostic de la pneumonie a gram negatif
CA2605959A1 (fr) Utilisation de lipopolysaccharide dans le condensat de souffle exhale pour le diagnostic de pneumonie a germes gram negatif
EP1904836A4 (fr) Systeme de codage de bande de diagnostic et methodes d'utilisation associees
DE602005009789D1 (de) Zyklonartiger Luftreiniger
DK1755552T3 (da) Mundplejefilm
EP1931255A4 (fr) Ensemble integre unite emettrice-et-mecanisme d'insertion de capteur, et procedes d'utilisation
EP1922514A4 (fr) Dissipateur thermique muni d'un revetement de plancher en graphite flexible
DE602006016206D1 (de) Multizyklon-Staubabscheider
DE602006017949D1 (de) Multizyklon-Staubabscheider
EP2036566A4 (fr) Utilisation de 20(s)-protopanoxadiol dans la fabrication d'antidépresseurs
EP2191023A4 (fr) Diagnostic d'un lymphome b
FI20041010L (fi) Järjestely intraoraaliröntgenkuvantamisen yhteydessä
EP2185069A4 (fr) Ensemble électropneumatique s'utilisant dans un système de mesure respiratoire
ITTO20060614A1 (it) "diagnosi differenziale per la sclerodermia"
DE602006007109D1 (de) Befeuchtungseinheit für Beatmungsgerät
EP2017257A4 (fr) Compose 2-aminobutanol et son utilisation a but medical
DE60322791D1 (de) Röntgendiagnostikgerät
EP1813565A4 (fr) Frein de secours d'ascenseur
FR2927004B1 (fr) Ensemble intercalaire pour un deshumidificateur d'air de type a pression
DE602005022072D1 (de) Kamerasystem für ein endoskop und endoskopsystem
ITVI20040286A1 (it) Sistema di illuminazione di emergenza a diagnosi centralizzata
FR2896179B1 (fr) Utilisation d'un systeme tridimensionnel a structure souple.
RU2007130783A (ru) Способ прогнозирования обострения бронхиальной астмы у детей на фоне острой респираторной инфекции путем определения уровня оксида азота в выдыхаемом воздухе
Krenova et al. Analysis of the renal damage following ethylene glycol poisoning
JP2009067750A5 (fr)

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20061207

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/04 20060101ALI20070424BHEP

Ipc: A61B 5/08 20060101AFI20070424BHEP

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1103513

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20090915

17Q First examination report despatched

Effective date: 20101011

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1103513

Country of ref document: HK

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20141202