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BRPI0511846A - utilização de lipopolissacarìdeo em condensado de respiração exalado para diagnosticar pneumonia gram-negativa - Google Patents

utilização de lipopolissacarìdeo em condensado de respiração exalado para diagnosticar pneumonia gram-negativa

Info

Publication number
BRPI0511846A
BRPI0511846A BRPI0511846-8A BRPI0511846A BRPI0511846A BR PI0511846 A BRPI0511846 A BR PI0511846A BR PI0511846 A BRPI0511846 A BR PI0511846A BR PI0511846 A BRPI0511846 A BR PI0511846A
Authority
BR
Brazil
Prior art keywords
lipopolysaccharide
exhaled breath
breathing
gram
breath condensate
Prior art date
Application number
BRPI0511846-8A
Other languages
English (en)
Inventor
Jeffrey A Kline
Jackeline Hernandez
John Albert Watts Jr
Original Assignee
Charlotte Mecklenburg Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charlotte Mecklenburg Hospital filed Critical Charlotte Mecklenburg Hospital
Publication of BRPI0511846A publication Critical patent/BRPI0511846A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/0813Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/097Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412Detecting or monitoring sepsis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)

Abstract

UTILIZAçãO DE LIPOPOLISSACARìDEO EM CONDENSADO DE RESPIRAçãO EXALADO PARA DIAGNOSTICAR PNEUMONIA GRAM-NEGATIVA. A presente invenção refere-se a um método para determinar se um indivíduo possui uma pneumonia bacteriana Gram-negativa com base na presença de lipopolissacarídeo em condensado de respiração exalado coletado a partir de um individuo. Os dispositivos de coleta utilizado para coletar condensado de respiração exalado tanto a partir de indivíduos que respiram espontaneamente ou mecanicamente ventilados e os dispositivos utilizados para determinar se o lipopolissacarídeo está presente no condensado de respiração exalado.
BRPI0511846-8A 2004-06-07 2005-05-24 utilização de lipopolissacarìdeo em condensado de respiração exalado para diagnosticar pneumonia gram-negativa BRPI0511846A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57764104P 2004-06-07 2004-06-07
PCT/US2005/018232 WO2006007180A2 (en) 2004-06-07 2005-05-24 Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia

Publications (1)

Publication Number Publication Date
BRPI0511846A true BRPI0511846A (pt) 2008-01-15

Family

ID=35784291

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511846-8A BRPI0511846A (pt) 2004-06-07 2005-05-24 utilização de lipopolissacarìdeo em condensado de respiração exalado para diagnosticar pneumonia gram-negativa

Country Status (8)

Country Link
EP (1) EP1761166A4 (pt)
JP (2) JP4804464B2 (pt)
AU (1) AU2005262701B2 (pt)
BR (1) BRPI0511846A (pt)
CA (1) CA2566804A1 (pt)
IL (5) IL179137A (pt)
MX (1) MXPA06014248A (pt)
WO (1) WO2006007180A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040138577A1 (en) 2002-12-20 2004-07-15 Kline Jeffrey A. Disposable hand-held device for collection of exhaled breath condensate
US7828741B2 (en) 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
WO2004073497A2 (en) 2003-02-14 2004-09-02 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate
CN101827558B (zh) * 2007-10-02 2013-03-27 安娜-卡林·奥林 呼出的粒子的采集和测量
WO2009149203A1 (en) * 2008-06-04 2009-12-10 Kci Licensing, Inc. Detecting infection in reduced pressure wound treatment
GB201312635D0 (en) * 2013-07-15 2013-08-28 Univ Plymouth Water testing
US10413216B2 (en) * 2016-02-03 2019-09-17 Quintron Instrument Company, Inc. Breath testing apparatus
CN106018362B (zh) * 2016-05-16 2018-06-08 江苏国恒检测有限公司 一种检测苦味酸的测定器
CN108871908B9 (zh) * 2018-09-06 2024-07-26 杭州优思达生物技术股份有限公司 生物样本处理装置
AU2020330524A1 (en) * 2019-08-13 2022-03-03 Respiration Scan Ltd System and method for determining onset and disease progression
KR102543496B1 (ko) * 2019-08-26 2023-06-13 제테오 테크, 인코포레이티드 호기를 이용한 결핵 및 기타 질병의 진단
WO2023038582A2 (en) * 2021-09-10 2023-03-16 National University Of Singapore Exhaled breath condensate collection kit
JP2024536778A (ja) * 2021-09-20 2024-10-08 ヴォスビオ,インコーポレーテッド 生物学的試料の捕捉および処理のためのデバイス、方法およびキット
AU2024283662A1 (en) * 2023-06-05 2025-12-04 Charles River Laboratories, Inc. Recombinant amebocyte clotting factors and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59383A (en) * 1980-02-14 1983-03-31 Technion Res & Dev Foundation Micromethod for the determination of endotoxins with limulus amebocyte lysate
US4349626A (en) * 1980-10-28 1982-09-14 The Monell Chemical Senses Center Method of detecting Pseudomonas aeruginosa infections utilizing selected ketone and/or sulfur metabolites
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
SE9704329D0 (sv) * 1997-11-25 1997-11-25 Siemens Elema Ab Gasmätare
JP2002541429A (ja) * 1998-12-18 2002-12-03 ユニバーシティ オブ バージニア パテント ファウンデーション 喘息を監視するための装置と方法
DE60020823T2 (de) * 1999-03-09 2006-05-18 Osmetech Plc, Crewe Diagnostisches verfahren durch analyse von kondensierung aus atmungs gas
EP1409985A4 (en) * 2000-05-01 2009-01-07 Respiratory Res Inc METHOD AND DEVICE FOR REMOVING AND ANALYZING EXTRACTED ATOM
US20040234971A1 (en) * 2001-02-01 2004-11-25 Joany Jackman Diagnosis of pathogen infections using mass spectral analysis of immune system modulators in post-exposure biological samples

Also Published As

Publication number Publication date
IL179137A0 (en) 2007-03-08
JP2009186487A (ja) 2009-08-20
MXPA06014248A (es) 2007-06-25
CA2566804A1 (en) 2006-01-19
IL179137A (en) 2012-07-31
AU2005262701B2 (en) 2011-12-01
WO2006007180A2 (en) 2006-01-19
IL218188A0 (en) 2012-04-30
EP1761166A2 (en) 2007-03-14
EP1761166A4 (en) 2009-11-11
JP4852121B2 (ja) 2012-01-11
AU2005262701A1 (en) 2006-01-19
WO2006007180A3 (en) 2006-11-30
JP4804464B2 (ja) 2011-11-02
JP2008501976A (ja) 2008-01-24
IL218189A0 (en) 2012-04-30
IL218190A0 (en) 2012-04-30
IL218191A0 (en) 2012-04-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2309 DE 07/04/2015.