EP1638566A4 - Imidazo-quinolines a substitution sulfonamide - Google Patents

Imidazo-quinolines a substitution sulfonamide

Info

Publication number: EP1638566A4
Authority: EP; European Patent Office
Prior art keywords: sulfonamide substituted; substituted imidazoquinolines; imidazoquinolines; sulfonamide; substituted
Prior art date: 2003-06-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP04756208A

Other languages

German (de)

English (en)

Other versions

EP1638566A2 (fr

Inventor

George W Griesgraber

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Coley Pharmaceutical Group Inc

Original Assignee

3M Innovative Properties Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-27

Filing date

2004-06-25

Publication date

2009-03-25

2004-06-25 Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co

2006-03-29 Publication of EP1638566A2 publication Critical patent/EP1638566A2/fr

2009-03-25 Publication of EP1638566A4 publication Critical patent/EP1638566A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EP04756208A 2003-06-27 2004-06-25 Imidazo-quinolines a substitution sulfonamide Withdrawn EP1638566A4 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US48320003P	2003-06-27	2003-06-27
PCT/US2004/020607 WO2005003065A2 (fr)	2003-06-27	2004-06-25	Imidazo-quinolines a substitution sulfonamide

Publications (2)

Publication Number	Publication Date
EP1638566A2 EP1638566A2 (fr)	2006-03-29
EP1638566A4 true EP1638566A4 (fr)	2009-03-25

Family

ID=33563911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP04756208A Withdrawn EP1638566A4 (fr)	2003-06-27	2004-06-25	Imidazo-quinolines a substitution sulfonamide

Country Status (16)

Country	Link
EP (1)	EP1638566A4 (fr)
JP (1)	JP2007521280A (fr)
KR (1)	KR20060035637A (fr)
CN (1)	CN1812789B (fr)
AR (2)	AR044922A1 (fr)
AU (1)	AU2004253929A1 (fr)
BR (1)	BRPI0411916A (fr)
CA (1)	CA2529322A1 (fr)
IL (1)	IL172427A0 (fr)
MX (1)	MXPA06000144A (fr)
MY (1)	MY157827A (fr)
NZ (1)	NZ544330A (fr)
RU (1)	RU2374246C2 (fr)
TW (2)	TW200514784A (fr)
WO (2)	WO2005003064A2 (fr)
ZA (1)	ZA200600769B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040265351A1 (en)	2003-04-10	2004-12-30	Miller Richard L.	Methods and compositions for enhancing immune response
AU2004266658A1 (en)	2003-08-12	2005-03-03	3M Innovative Properties Company	Hydroxylamine substituted imidazo-containing compounds
BRPI0413998A (pt)	2003-08-27	2006-11-07	3M Innovative Properties Co	imidazoquinolinas arilóxi e arilalquilenóxi substituìdas
US20050054665A1 (en)	2003-09-05	2005-03-10	3M Innovative Properties Company	Treatment for CD5+ B cell lymphoma
US7544697B2 (en)	2003-10-03	2009-06-09	Coley Pharmaceutical Group, Inc.	Pyrazolopyridines and analogs thereof
BRPI0414856A (pt)	2003-10-03	2006-11-21	3M Innovative Properties Co	imidazoquinolinas alcóxi-substituìdas
JP2007508305A (ja)	2003-10-03	2007-04-05	スリーエムイノベイティブプロパティズカンパニー	ピラゾロピリジンおよびその類似物
CA2545825A1 (fr)	2003-11-14	2005-06-02	3M Innovative Properties Company	Composes d'un anneau d'imidazo substitue par hydroxylamine
WO2005048933A2 (fr)	2003-11-14	2005-06-02	3M Innovative Properties Company	Composes d'un anneau d'imidazo substitues par oxime
CA2547020C (fr)	2003-11-25	2014-03-25	3M Innovative Properties Company	Derives de 1h-imidazo[4,5-c]pyridine-4-amine en tant que compose modificateur de la reponse immunitaire
US8940755B2 (en) *	2003-12-02	2015-01-27	3M Innovative Properties Company	Therapeutic combinations and methods including IRM compounds
WO2005066170A1 (fr)	2003-12-29	2005-07-21	3M Innovative Properties Company	Imidazoquinolines a substitution arylalcenyle et arylalkynyle
AU2004312508A1 (en)	2003-12-30	2005-07-21	3M Innovative Properties Company	Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
TW200612932A (en)	2004-03-24	2006-05-01	3M Innovative Properties Co	Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (fr)	2004-06-15	2005-12-29	3M Innovative Properties Company	Imidazoquinolines et imidazonaphthyridines substituees par un heterocyclyle contenant un azote
US7915281B2 (en)	2004-06-18	2011-03-29	3M Innovative Properties Company	Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
WO2006009826A1 (fr)	2004-06-18	2006-01-26	3M Innovative Properties Company	Thiazoloquinolines et thiazolonaphtyridines substitues par aryloxy et arylalkyleneoxy
US7897609B2 (en)	2004-06-18	2011-03-01	3M Innovative Properties Company	Aryl substituted imidazonaphthyridines
US8541438B2 (en)	2004-06-18	2013-09-24	3M Innovative Properties Company	Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
AU2005322898B2 (en)	2004-12-30	2011-11-24	3M Innovative Properties Company	Chiral fused (1,2)imidazo(4,5-c) ring compounds
US8034938B2 (en)	2004-12-30	2011-10-11	3M Innovative Properties Company	Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
AU2005323024A1 (en) *	2004-12-30	2006-07-13	3M Innovative Properties Company	Multi-route administration of immune response modifier compounds
US9248127B2 (en)	2005-02-04	2016-02-02	3M Innovative Properties Company	Aqueous gel formulations containing immune response modifiers
AU2006212765B2 (en)	2005-02-09	2012-02-02	3M Innovative Properties Company	Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
US7968563B2 (en)	2005-02-11	2011-06-28	3M Innovative Properties Company	Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
WO2006107851A1 (fr)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Composes cycliques 1-pyrazolo[3,4-c] substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques
CA2602683A1 (fr)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Pyrazolopyridine-1,4-diamines et analogues associes
ZA200803029B (en) *	2005-09-09	2009-02-25	Coley Pharm Group Inc	Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
BRPI0615788A2 (pt)	2005-09-09	2011-05-24	Coley Pharm Group Inc	derivados de amida e carbamato de n-{2-[4-amino (etoximetil)-1h-imidazo [4,5-c] quinolin-1-il]-1,1-dimetiletil} metanossulfonamida, composição farmacêutica destes e seus usos
JP4551962B2 (ja) *	2005-09-23	2010-09-29	コーリーファーマシューティカルグループ，インコーポレイテッド	１Ｈ−イミダゾ［４，５−ｃ］ピリジンおよびその類似体のための方法
US8951528B2 (en)	2006-02-22	2015-02-10	3M Innovative Properties Company	Immune response modifier conjugates
WO2008008432A2 (fr)	2006-07-12	2008-01-17	Coley Pharmaceutical Group, Inc.	Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants
PL2276486T3 (pl) *	2008-03-24	2014-04-30	4Sc Discovery Gmbh	Nowe podstawione imidazochinoliny
SI2606047T1 (sl)	2010-08-17	2017-04-26	3M Innovative Properties Company	Lipidirani sestavki spojine, ki modificira imunski odgovor, formulacije in postopki
US9475804B2 (en)	2011-06-03	2016-10-25	3M Innovative Properties Company	Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom
EP2718292B1 (fr)	2011-06-03	2018-03-14	3M Innovative Properties Company	Hydrazino 1h-imidazoquinoléine-4-amines et conjugués obtenus à partir de celles-ci
WO2015092592A1 (fr)	2013-12-17	2015-06-25	Pfizer Inc.	Nouvelles 1h-pyrrolo[2,3- b]pyridines 3,4-disubstituées et 7h-pyrrolo[2,3-c]pyridazines 4,5-disubstituées en tant qu'inhibiteurs de la lrrk2
KR102161364B1 (ko)	2015-09-14	2020-09-29	화이자 인코포레이티드	LRRK2 억제제로서 이미다조[4,5-c]퀴놀린 및 이미다조[4,5-c][1,5]나프티리딘 유도체
CA3029902A1 (fr)	2016-07-07	2018-01-11	The Board Of Trustees Of The Leland Stanford Junior University	Conjugues d'adjuvant d'anticorps
MX2019010756A (es)	2017-03-10	2020-01-20	Pfizer	Derivados novedosos de imidazo[4,5-c]quinolina como inhibidores de cinasa 2 rica en repetición de leucina (lrrk2).
HUE058995T2 (hu)	2017-09-06	2022-10-28	BioNTech SE	Szubsztituált imidazokinolinok mint a TLR7 agonistái
CN111511740B (zh)	2017-12-20	2023-05-16	3M创新有限公司	用作免疫应答调节剂的带有支链连接基团的酰胺取代的咪唑并[4,5-c]喹啉化合物
CA3130794A1 (fr)	2019-03-15	2020-09-24	Bolt Biotherapeutics, Inc.	Immunoconjugues ciblant le her2
JP2023507322A (ja) *	2019-12-20	2023-02-22	ナミセラピューティクス，インコーポレイテッド	がんの処置において有用なＴｏｌｌ様受容体（「ＴＬＲ」）アゴニストプロドラッグを含有する製剤化および／または共製剤化リポソーム組成物ならびにその方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000076519A1 (fr) *	1999-06-10	2000-12-21	3M Innovative Properties Company	Imidazoquinolines substituees sulfonamide et sulfamide
US6677349B1 (en) *	2001-12-21	2004-01-13	3M Innovative Properties Company	Sulfonamide and sulfamide substituted imidazoquinolines

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PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
WO1998030562A1 (fr) *	1997-01-09	1998-07-16	Terumo Kabushiki Kaisha	Nouveaux derives d'amide et intermediaires utilises pour leur synthese
IL124914A (en) *	1997-06-26	2000-10-31	Akzo Nobel Nv	Pharmaceutical compositions containing 6-aryl-2,3,5,6-tetrahydroimidazo¬2,1-a¾isoquinoline derivatives and some new such compounds
JP2000119271A (ja) *	1998-08-12	2000-04-25	Hokuriku Seiyaku Co Ltd	１ｈ―イミダゾピリジン誘導体
EP1486495B1 (fr) *	1998-10-26	2009-12-09	The Research Foundation of State University of New York	Sels de dérives de l'acide lipoique et leur utilisation dans le traitement des maladies
AU2002343728A1 (en) *	2001-11-16	2003-06-10	3M Innovative Properties Company	Methods and compositions related to irm compounds and toll-like receptor pathways

2004
- 2004-06-24 MY MYPI20042461A patent/MY157827A/en unknown
- 2004-06-25 AR ARP040102247A patent/AR044922A1/es unknown
- 2004-06-25 CA CA002529322A patent/CA2529322A1/fr not_active Abandoned
- 2004-06-25 WO PCT/US2004/020606 patent/WO2005003064A2/fr not_active Ceased
- 2004-06-25 EP EP04756208A patent/EP1638566A4/fr not_active Withdrawn
- 2004-06-25 KR KR1020057024904A patent/KR20060035637A/ko not_active Ceased
- 2004-06-25 NZ NZ544330A patent/NZ544330A/en unknown
- 2004-06-25 AR ARP040102248A patent/AR044923A1/es unknown
- 2004-06-25 AU AU2004253929A patent/AU2004253929A1/en not_active Abandoned
- 2004-06-25 JP JP2006517711A patent/JP2007521280A/ja active Pending
- 2004-06-25 CN CN2004800181459A patent/CN1812789B/zh not_active Expired - Fee Related
- 2004-06-25 TW TW093118635A patent/TW200514784A/zh unknown
- 2004-06-25 RU RU2005138915/04A patent/RU2374246C2/ru not_active IP Right Cessation
- 2004-06-25 BR BRPI0411916-9A patent/BRPI0411916A/pt not_active IP Right Cessation
- 2004-06-25 TW TW093118636A patent/TW200511992A/zh unknown
- 2004-06-25 MX MXPA06000144A patent/MXPA06000144A/es unknown
- 2004-06-25 WO PCT/US2004/020607 patent/WO2005003065A2/fr not_active Ceased
2005
- 2005-12-07 IL IL172427A patent/IL172427A0/en unknown
2006
- 2006-01-26 ZA ZA200600769A patent/ZA200600769B/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000076519A1 (fr) *	1999-06-10	2000-12-21	3M Innovative Properties Company	Imidazoquinolines substituees sulfonamide et sulfamide
US6677349B1 (en) *	2001-12-21	2004-01-13	3M Innovative Properties Company	Sulfonamide and sulfamide substituted imidazoquinolines

Also Published As

Publication number	Publication date
EP1638566A2 (fr)	2006-03-29
NZ544330A (en)	2009-06-26
MY157827A (en)	2016-07-29
WO2005003064A2 (fr)	2005-01-13
JP2007521280A (ja)	2007-08-02
TW200514784A (en)	2005-05-01
CN1812789A (zh)	2006-08-02
CN1812789B (zh)	2010-07-14
RU2374246C2 (ru)	2009-11-27
MXPA06000144A (es)	2006-04-07
AR044923A1 (es)	2005-10-12
WO2005003065A2 (fr)	2005-01-13
ZA200600769B (en)	2007-05-30
AR044922A1 (es)	2005-10-12
AU2004253929A1 (en)	2005-01-13
WO2005003064A3 (fr)	2005-03-31
KR20060035637A (ko)	2006-04-26
CA2529322A1 (fr)	2005-01-13
RU2005138915A (ru)	2006-06-27
BRPI0411916A (pt)	2006-08-15
IL172427A0 (en)	2006-04-10
TW200511992A (en)	2005-04-01
WO2005003065A3 (fr)	2005-03-10

Publication	Publication Date	Title
IL172427A0 (en)	2006-04-10	Sulfonamide substituted imidazoquinolines
ZA200603879B (en)	2010-01-27	Substituted indazole-O-glucosides
IL175490A0 (en)	2011-08-01	Substituted indazole-o-glucosides
EP1680131A4 (fr)	2009-05-27	Indole- o -glucosides substitues
ZA200603880B (en)	2010-01-27	Substituted indole-O-glucosides
SI1594840T1 (sl)	2006-12-31	Derivati piperidin-benzensulfonamida
GB0317665D0 (en)	2003-09-03	Qinazoline derivatives
PL1682493T3 (pl)	2009-06-30	Pochodne amidoacetonitrylu
DE502004009243D1 (en)	2009-05-07	Spirocyclische cyclohexan-derivate
SI1606277T1 (sl)	2008-08-31	Derivati imidazol-4-il-etinil-piridina
TWI368482B (en)	2012-07-21	New 2-pyridinylethylbenzamide derivatives
DE502004003476D1 (en)	2007-05-24	Standfuss
GB0329314D0 (en)	2004-01-21	Substituted arylpyrazoles
DE502004006683D1 (en)	2008-05-08	Injection-locked-oscillator-schaltkreis
IL175189A0 (en)	2006-09-05	N-thiazol-2-yl-benzamide derivatives
DE502004004146D1 (en)	2007-08-02	Pyrazolverbindungen
DE112004002769D2 (en)	2006-11-09	Schienengeführtes transportsystem
PL1706373T3 (pl)	2010-05-31	Pochodne amidoacetonitrylu
DE502004011343D1 (en)	2010-08-12	Rotorspinnmaschine
ZA200600430B (en)	2009-08-26	Substituted spirobenzazepines
DE10394343D2 (en)	2006-08-24	Berührungslose biometrische erkennung
GB0316128D0 (en)	2003-08-13	Novel sulfonamide compounds
GB0319793D0 (en)	2003-09-24	Pyridinylmorpholine derivatives
AU155419S (en)	2004-05-13	Trivette
TW573910U (en)	2004-01-21	Pivot

Legal Events

Date	Code	Title	Description
2006-02-10	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2006-03-29	17P	Request for examination filed	Effective date: 20060110
2006-03-29	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
2006-10-04	DAX	Request for extension of the european patent (deleted)
2009-03-25	A4	Supplementary search report drawn up and despatched	Effective date: 20090223
2009-08-26	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: COLEY PHARMACEUTICAL GROUP, INC.
2009-10-07	17Q	First examination report despatched	Effective date: 20090903
2009-10-07	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: COLEY PHARMACEUTICAL GROUP, INC.
2010-10-22	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2010-11-24	18D	Application deemed to be withdrawn	Effective date: 20100515