EP1436395A4 - Methodes d'identification et d'utilisation de modulateurs du recepteur gamma dependant des oestrogenes - Google Patents
Methodes d'identification et d'utilisation de modulateurs du recepteur gamma dependant des oestrogenesInfo
- Publication number
- EP1436395A4 EP1436395A4 EP02776223A EP02776223A EP1436395A4 EP 1436395 A4 EP1436395 A4 EP 1436395A4 EP 02776223 A EP02776223 A EP 02776223A EP 02776223 A EP02776223 A EP 02776223A EP 1436395 A4 EP1436395 A4 EP 1436395A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- modulators
- identifying
- methods
- receptor gamma
- related receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/108—Osteoporosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/362—Menopause
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32988801P | 2001-10-16 | 2001-10-16 | |
| US329888P | 2001-10-16 | ||
| PCT/US2002/032917 WO2003034028A2 (fr) | 2001-10-16 | 2002-10-16 | Methodes d'identification et d'utilisation de modulateurs du recepteur gamma dependant des oestrogenes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1436395A2 EP1436395A2 (fr) | 2004-07-14 |
| EP1436395A4 true EP1436395A4 (fr) | 2006-12-13 |
Family
ID=23287445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02776223A Withdrawn EP1436395A4 (fr) | 2001-10-16 | 2002-10-16 | Methodes d'identification et d'utilisation de modulateurs du recepteur gamma dependant des oestrogenes |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1436395A4 (fr) |
| JP (1) | JP2005509628A (fr) |
| AU (1) | AU2002342058A1 (fr) |
| WO (1) | WO2003034028A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006130503A2 (fr) * | 2005-05-27 | 2006-12-07 | Janssen Pharmaceutica N.V. | Complexes de fragments de peptides errg et utilisation de ceux-ci dans un nouveau medicament |
| KR101631581B1 (ko) * | 2010-06-11 | 2016-06-17 | 한국생명공학연구원 | 나노입자가 융합된 fret 센서 및 이를 이용한 파이토에스트로겐을 고감도로 검출하는 방법 |
| KR101579008B1 (ko) * | 2013-09-25 | 2015-12-22 | 경북대학교 산학협력단 | ERR-γ 저해제를 포함하는, 망막병증의 예방 또는 치료용 약학적 조성물 및 이의 용도 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096301A (en) * | 1986-10-10 | 2000-08-01 | Industria Farmaceutica Serono Spa | Combined interferon/antiestrogen therapy for treatment of breast cancer |
| US6218128B1 (en) * | 1997-09-12 | 2001-04-17 | Allergan Sales, Inc. | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities |
-
2002
- 2002-10-16 JP JP2003536715A patent/JP2005509628A/ja active Pending
- 2002-10-16 WO PCT/US2002/032917 patent/WO2003034028A2/fr not_active Ceased
- 2002-10-16 AU AU2002342058A patent/AU2002342058A1/en not_active Abandoned
- 2002-10-16 EP EP02776223A patent/EP1436395A4/fr not_active Withdrawn
Non-Patent Citations (4)
| Title |
|---|
| COWARD P ET AL: "4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 98, no. 15, 17 July 2001 (2001-07-17), pages 8880 - 8884, XP002971442, ISSN: 0027-8424 * |
| HEARD D J ET AL: "Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult.", MOLECULAR ENDOCRINOLOGY (BALTIMORE, MD.) MAR 2000, vol. 14, no. 3, March 2000 (2000-03-01), pages 382 - 392, XP002404547, ISSN: 0888-8809 * |
| SHIAU A K ET AL: "ORPHAN NUCLEAR RECEPTORS: FROM NEW LIGAND DISCOVERY TECHNOLOGIES TO NOVEL SIGNALING PATHWAYS", CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT, CURRENT DRUGS, LONDON, GB, vol. 4, no. 5, September 2001 (2001-09-01), pages 575 - 590, XP009031659, ISSN: 1367-6733 * |
| TREMBLAY G B ET AL: "4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related(ERR) nuclear receptors beta and gamma", ENDOCRINOLOGY, BALTIMORE, MD, US, vol. 142, no. 10, 2001, pages 4572 - 4575, XP002967678, ISSN: 0013-7227 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005509628A (ja) | 2005-04-14 |
| AU2002342058A1 (en) | 2003-04-28 |
| WO2003034028A2 (fr) | 2003-04-24 |
| EP1436395A2 (fr) | 2004-07-14 |
| WO2003034028A3 (fr) | 2004-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20040416 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/574 20060101ALI20061030BHEP Ipc: C07K 14/00 20060101ALI20061030BHEP Ipc: C12N 5/00 20060101ALI20061030BHEP Ipc: C12N 15/63 20060101ALI20061030BHEP Ipc: C12N 15/12 20060101AFI20040422BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20061109 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20070209 |