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EP1336390B1 - Tube having an insert adapter - Google Patents

Tube having an insert adapter Download PDF

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Publication number
EP1336390B1
EP1336390B1 EP03011412A EP03011412A EP1336390B1 EP 1336390 B1 EP1336390 B1 EP 1336390B1 EP 03011412 A EP03011412 A EP 03011412A EP 03011412 A EP03011412 A EP 03011412A EP 1336390 B1 EP1336390 B1 EP 1336390B1
Authority
EP
European Patent Office
Prior art keywords
insert
tube
straw
substances
straw according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP03011412A
Other languages
German (de)
French (fr)
Other versions
EP1336390A1 (en
Inventor
Jean-Gérard Saint-Ramon
Christian Beau
Alain Ehrsam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMV Technologies SA
Original Assignee
IMV Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMV Technologies SA filed Critical IMV Technologies SA
Publication of EP1336390A1 publication Critical patent/EP1336390A1/en
Application granted granted Critical
Publication of EP1336390B1 publication Critical patent/EP1336390B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00Instruments or methods for reproduction or fertilisation
    • A61D19/02Instruments or methods for reproduction or fertilisation for artificial insemination
    • A61D19/022Containers for animal semen, e.g. pouches or vials ; Methods or apparatus for treating or handling animal semen containers, e.g. filling or closing
    • A61D19/024Tube-like containers, e.g. straws

Definitions

  • the present invention relates to a straw for the preservation of small amounts of substances, especially biological substances, in particular biological liquids.
  • the flakes used up to now comprise a tripartite stopper consisting of two buffers of a fibrous substance enclosing a powder capable of being transformed on contact with a liquid into an impermeable paste or gel adhering to the wall of the tube, creating a tight plug .
  • French patent N ° 1,488,345 describes various improvements, in particular the provision of a plastic tube forcefully introduced to hold the plug in place during filling
  • An object of the invention is to provide a straw comprising a filling indicator.
  • the present invention meets the above object and provides a straw for the preservation of small amounts of substances, especially biological substances, consisting of a tube segment, wherein said tube segment is provided inside. at one of its ends an insert pierced with a substantially coaxial orifice, characterized in that the insert is a capillary tube serving as a filling indicator.
  • the straw With such a capillary insert, the straw is used without a cap.
  • the insert thus serves as a filling indicator.
  • the insert is usually made of a material selected from elastomeric materials, thermoplastic materials and thermoplastic elastomeric materials. It can also be metal or any other suitable material.
  • the end of the straw comprising the insert according to the invention remains normally open for the introduction of the product to be preserved, which is usually a liquid.
  • the open end is closed, for example by welding, including ultrasound or heat, or any other suitable technique known to those skilled in the art.
  • the diameter of the inner orifice of the insert usually has a diameter of between about 0.5 mm and 2 mm, but not exclusively.
  • figure 1 is a longitudinal sectional view of a straw according to the invention.
  • the flake 1 consists of a tube segment 2 provided with the insert 3 pierced with a substantially coaxial capillary orifice, without plug.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Closures For Containers (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Table Equipment (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Adornments (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The pipette (1) to store small vols. of substances, and especially biological material, has a tubular section (2) with a perforated inert (3) within it, with a coaxial opening (4) through it. The insert (3) is of an elastomer, thermoplastic or thermoplastic elastomer material, or it is of metal. The passage through the insert is closed by a plug (5).

Description

La présente invention concerne une paillette pour la conservation de petites quantités de substances, notamment des substances biologiques, en particulier des liquides biologiques.The present invention relates to a straw for the preservation of small amounts of substances, especially biological substances, in particular biological liquids.

Ce type de paillette, connue sous la dénomination de "paillette française", a été divulgué pour la première fois dans le brevet français N° 995 878 .This type of straw, known under the name of "French straw", was disclosed for the first time in the French patent No. 995,878 .

Les paillettes utilisées jusqu'à présent comprennent un bouchon tripartite constitué par deux tampons d'une substance fibreuse enserrant une poudre susceptible de se transformer au contact d'un liquide en une pâte ou gel imperméable adhérant à la paroi du tube en créant un bouchon étanche.The flakes used up to now comprise a tripartite stopper consisting of two buffers of a fibrous substance enclosing a powder capable of being transformed on contact with a liquid into an impermeable paste or gel adhering to the wall of the tube, creating a tight plug .

Les paillettes à bouchon tripartite mises au point et commercialisées par la Demanderesse donnent toute satisfaction. Néanmoins, une certaine absorption de liquide contenu dans la paillette a pu être constatée, quoique très faible.The sequins tripartite plug developed and marketed by the Applicant are very satisfactory. Nevertheless, some absorption of liquid contained in the straw has been observed, albeit very weak.

Il existe des paillettes de différents diamètres. Pour des paillettes de grand diamètre, par exemple, 3,7 mm, le bouchon tripartie aura une taille plus importante et l'absorption y sera d'autant plus conséquente.There are straws of different diameters. For flakes of large diameter, for example, 3.7 mm, the tripartite plug will have a larger size and absorption will be all the more consistent.

Le brevet français N° 1 488 345 décrit divers perfectionnements, en particulier la prévision d'un tube de plastique introduit en force pour maintenir en place le bouchon lors du remplissageFrench patent N ° 1,488,345 describes various improvements, in particular the provision of a plastic tube forcefully introduced to hold the plug in place during filling

Un objet de l'invention est de fournir une paillette comportant un indicateur de remplissage.An object of the invention is to provide a straw comprising a filling indicator.

D'autres objets et avantages de l'invention apparaîtront à la lecture de la description ci-après.Other objects and advantages of the invention will appear on reading the description below.

La présente invention répond à l'objet ci-dessus et fournit une paillette pour la conservation de petites quantités de substances, notamment de substances biologiques, se composant d'un segment de tube, dans laquelle ledit segment de tube est muni à l'intérieur de l'une de ses extrémités d'un insert percé d'un orifice sensiblement coaxial, caractérisée en ce que l'insert est un tube capillaire servant d'indicateur de remplissage.The present invention meets the above object and provides a straw for the preservation of small amounts of substances, especially biological substances, consisting of a tube segment, wherein said tube segment is provided inside. at one of its ends an insert pierced with a substantially coaxial orifice, characterized in that the insert is a capillary tube serving as a filling indicator.

Avec un tel insert capillaire, la paillette est utilisée sans bouchon. L'insert sert ainsi d'indicateur de remplissage.With such a capillary insert, the straw is used without a cap. The insert thus serves as a filling indicator.

L'insert est habituellement en un matériau choisi parmi les matériaux élastomères, les matériaux thermoplastiques et les matériaux élastomères thermoplastiques. Il peut également être en métal ou en tout autre matériau approprié.The insert is usually made of a material selected from elastomeric materials, thermoplastic materials and thermoplastic elastomeric materials. It can also be metal or any other suitable material.

L'extrémité de la paillette ne comportant par l'insert selon l'invention, demeure normalement ouverte pour l'introduction du produit à conserver, qui est généralement un liquide.The end of the straw comprising the insert according to the invention remains normally open for the introduction of the product to be preserved, which is usually a liquid.

Pour mettre le produit chargé à l'abri de toute contamination, l'extrémité ouverte est obturée, par exemple par soudage, notamment aux ultrasons ou thermique, ou toute autre technique appropriée connue de l'homme de l'art.To put the charged product away from contamination, the open end is closed, for example by welding, including ultrasound or heat, or any other suitable technique known to those skilled in the art.

Il est par ailleurs avantageux de pouvoir marquer les paillettes par "code couleur" sans avoir à recourir à des paillettes colorées. Ceci peut être effectué selon la présente invention en choisissant un insert en un matériau thermoplastique coloré ou en matériau élastomère thermoplastique coloré.It is also advantageous to be able to mark the flakes by "color code" without having to resort to colored flakes. This can be done according to the present invention by choosing an insert made of colored thermoplastic material or colored thermoplastic elastomer material.

Ici, où l'insert est un capillaire, le diamètre de l'orifice intérieur de l'insert a habituellement un diamètre compris entre environ 0,5 mm et 2 mm, mais pas exclusivement.Here, where the insert is a capillary, the diameter of the inner orifice of the insert usually has a diameter of between about 0.5 mm and 2 mm, but not exclusively.

L'invention sera à présent illustrée de façon non limitative en référence au dessin annexé dans lequel la figure 1 est une vue en coupe longitudinale d'une paillette selon l'invention.The invention will now be illustrated in a nonlimiting manner with reference to the appended drawing in which the figure 1 is a longitudinal sectional view of a straw according to the invention.

Dans la figure 1, la paillette 1 est constituée d'un segment de tube 2 muni de l'insert 3 percé d'un orifice capillaire sensiblement coaxial, sans bouchon.In the figure 1 , the flake 1 consists of a tube segment 2 provided with the insert 3 pierced with a substantially coaxial capillary orifice, without plug.

L'homme de l'art comprendra que bien que l'invention ait été décrite et illustrée pour des modes de réalisation particuliers, de nombreuses variantes peuvent être envisagées tout en restant dans le cadre de l'invention tel que défini dans les revendications annexées.It will be understood by those skilled in the art that although the invention has been described and illustrated for particular embodiments, many alternatives may be contemplated while remaining within the scope of the invention as defined in the appended claims.

Claims (5)

  1. Straw (1) for the conservation of small quantities of substances, in particular of biological substances, consisting of a segment of tube (2), in which said segment of tube is provided, inside one end, with an insert (3) with a substantially coaxial orifice (4) through it, characterised in that the insert is a capillary tube serving as a filling indicator.
  2. Straw according to claim 1, characterised in that the insert is made from a material chosen from elastomer materials, thermoplastics materials and thermoplastics elastomer materials.
  3. Straw according to claim 1, characterised in that the insert is made from a material chosen from the metals.
  4. Straw according to claim 2, characterised in that the insert is colored.
  5. Straw according to any one of claims 1 to 4, characterized in that the diameter of the orifice inside the insert is between 0.5 mm and 2 mm.
EP03011412A 1997-11-24 1998-11-23 Tube having an insert adapter Expired - Lifetime EP1336390B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9714728A FR2771284B1 (en) 1997-11-24 1997-11-24 GLITTER WITH ADAPTER INSERT
FR9714728 1997-11-24
EP98402910A EP0917862B1 (en) 1997-11-24 1998-11-23 Tube having an insert adapter

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP98402910A Division EP0917862B1 (en) 1997-11-24 1998-11-23 Tube having an insert adapter
EP98402910.8 Division 1998-11-23

Publications (2)

Publication Number Publication Date
EP1336390A1 EP1336390A1 (en) 2003-08-20
EP1336390B1 true EP1336390B1 (en) 2012-09-05

Family

ID=9513716

Family Applications (2)

Application Number Title Priority Date Filing Date
EP03011412A Expired - Lifetime EP1336390B1 (en) 1997-11-24 1998-11-23 Tube having an insert adapter
EP98402910A Expired - Lifetime EP0917862B1 (en) 1997-11-24 1998-11-23 Tube having an insert adapter

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP98402910A Expired - Lifetime EP0917862B1 (en) 1997-11-24 1998-11-23 Tube having an insert adapter

Country Status (6)

Country Link
US (1) US6300125B1 (en)
EP (2) EP1336390B1 (en)
AT (1) ATE250900T1 (en)
DE (2) DE29820910U1 (en)
DK (1) DK0917862T3 (en)
FR (1) FR2771284B1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2771285B1 (en) * 1997-11-24 2000-02-11 Instr Medecine Veterinaire GLITTER WITH BIPARTITE CAP
FR2804416B1 (en) 2000-01-31 2002-04-26 Imv Technologies CONVEYOR AND TUBE POSITIONING MACHINE, ESPECIALLY FLAKES
FR2824255B1 (en) 2001-05-07 2004-02-06 Imv Technologies STRAW FOR THE PRESERVATION OF SMALL QUANTITIES OF SUBSTANCES, ESPECIALLY BIOLOGICAL LIQUIDS
FR2824256B1 (en) 2001-05-07 2004-04-02 Imv Technologies STRAW FOR THE PRESERVATION OF SMALL QUANTITIES OF SUBSTANCES, ESPECIALLY BIOLOGICAL LIQUIDS
EP2198804A1 (en) 2008-12-18 2010-06-23 IMV Technologies Straw for the conservation of a predetermined dose of a liquid base substance, in particular a biological substance
FR3004332B1 (en) * 2013-04-11 2018-03-02 Imv Technologies STRAW FOR PRESERVING A PREDETERMINED DOSE OF A LIQUID-BASED SUBSTANCE, IN PARTICULAR PURE OR DILUTED ANIMAL SEED
FR3036954B1 (en) 2015-06-03 2017-07-14 Imv Tech STRAW FOR PRESERVING A PREDETERMINED DOSE OF LIQUID-BASED SUBSTANCE, AND INJECTION DEVICE AND METHOD FOR CARRYING OUT THE SAME
FR3074419B1 (en) 2017-12-05 2019-12-27 Imv Technologies GLITTER FOR THE CRYOGENIC PRESERVATION OF A DOSE OF LIQUID-BASED SUBSTANCE, ASSEMBLY COMPRISING SAME AND METHOD FOR EMPTYING THE GLITTER
FR3100442B1 (en) * 2019-09-09 2021-09-24 Imv Tech Assembly for handling a plurality of animal semen packaging straws

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE498210A (en) 1949-09-20
FR1488345A (en) * 1966-05-26 1967-07-13 Process and equipment for collecting and conditioning sets intended for the artificial insemination of birds and small mammals
FR2539628B1 (en) * 1983-01-25 1988-11-10 Fondation Rech Hormonologie PROCESS FOR SEPARATING MOBILE CELLS, ESPECIALLY MOBILE SPERMATOZOIDS, AND A DEVICE FOR CARRYING OUT SAID METHOD
US4558014A (en) * 1983-06-13 1985-12-10 Myron J. Block Assay apparatus and methods
FR2651793B1 (en) * 1989-09-14 1991-12-06 Cassou Robert TUBES OR SEQUINS FOR THE CRYOGENIC PRESERVATION OF BIOLOGICAL SAMPLES SUCH AS VIRUSES, AND FILLING METHOD.
FR2762210B1 (en) 1997-04-21 1999-07-02 Instr Medecine Veterinaire GLITTER WITH A FULL MICROPOROUS FIBER CAP

Also Published As

Publication number Publication date
DE69818610D1 (en) 2003-11-06
DE29820910U1 (en) 1999-02-04
FR2771284B1 (en) 2000-08-18
EP0917862A1 (en) 1999-05-26
US6300125B1 (en) 2001-10-09
EP1336390A1 (en) 2003-08-20
ATE250900T1 (en) 2003-10-15
EP0917862B1 (en) 2003-10-01
FR2771284A1 (en) 1999-05-28
DK0917862T3 (en) 2004-01-12

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