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WO1998038095A1 - Flask specifically designed for packaging biological analysis reagents and method for packaging biological analysis reagents - Google Patents

Flask specifically designed for packaging biological analysis reagents and method for packaging biological analysis reagents Download PDF

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Publication number
WO1998038095A1
WO1998038095A1 PCT/FR1998/000353 FR9800353W WO9838095A1 WO 1998038095 A1 WO1998038095 A1 WO 1998038095A1 FR 9800353 W FR9800353 W FR 9800353W WO 9838095 A1 WO9838095 A1 WO 9838095A1
Authority
WO
WIPO (PCT)
Prior art keywords
biological analysis
bottle
analysis reagents
packaging
hollow body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1998/000353
Other languages
French (fr)
Inventor
Nicolas Bara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Central Labo Europe SAS
Original Assignee
Central Labo Europe SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central Labo Europe SAS filed Critical Central Labo Europe SAS
Publication of WO1998038095A1 publication Critical patent/WO1998038095A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261—Bottom construction
    • B65D1/0284—Bottom construction having a discontinuous contact surface, e.g. discrete feet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/08—Flasks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D23/00—Details of bottles or jars not otherwise provided for
    • B65D23/001—Supporting means fixed to the container
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers

Definitions

  • Bottle intended specifically for packaging biological analysis reagents and method for packaging biological analysis reagents.
  • the present invention relates to bottles intended specifically for packaging biological analysis reagents. These bottles are in the state of the art glass or plastic bottles having a cylindrical interior volume, with a flat bottom. These bottles are often used with pipetting machines. Biological analysis reagents are very expensive products, and it is therefore essential to avoid any loss of product.
  • the object of the present invention is to remedy the drawbacks of the bottles of the state of the art by proposing an improved bottle reducing the loss of products, in particular of the last drops of reagent.
  • the invention relates generally to a bottle intended specifically for the packaging of biological analysis reagents formed by a hollow body closable by a stopper characterized in that the bottom of the hollow body is of concave shape. Such a bottom allows recovery of the entire reagent with pipettes, in particular with automatic pipettes.
  • the bottom of the hollow body is of conical shape.
  • the generator of the bottom forms an angle of about 30 degrees with the plane perpendicular to the axis of the bottle.
  • the bottle has walls of substantially constant thickness, the bottom being extended by a stabilization base.
  • the bottle has thin walls extended at the bottom by a cylindrical skirt.
  • the bottle has a neck connected to the central part of the hollow body by conical walls to facilitate the recovery of condensate.
  • the section of the neck is less than 0.6 times the section of the hollow body.
  • the invention also relates to a method for packaging reagents for biological analysis, characterized in that they are stored in bottles having a concave bottom.
  • Figure 1 shows a perspective view of a first embodiment of a bottle according to the invention
  • FIG. 2 shows a perspective view of a second embodiment of a bottle according to the invention
  • FIG. 3 represents a perspective view of a third embodiment of a bottle according to the invention.
  • Figure 1 shows a perspective view of a first embodiment of a bottle according to the invention. It consists of a container, for example made of plastic such as PET, and has a hollow interior volume, the central part (1) of which is cylindrical. The central part (1) is extended downwards by a conical part
  • the bottom has a semi-spherical central part (4), of a section substantially equal to the external section of a pipette, facilitating the positioning of the head of a pipette and the recovery of the last quantities of reagents.
  • the central part is extended at the end opposite the bottom (2) by a conical part
  • the conical part (5) leads to a significant reduction in section, and has walls forming an angle of 30 to 45 ° with the transverse plane. This conical part (5) facilitates the recovery of condensates and reduces the loss of products by evaporation.
  • the neck (6) has on its outer surface a thread (7) capable of cooperating with a screw cap (8) known per se. A seal (9) can be interposed between the neck (6) and the plug (8).
  • the bottom has an extra thickness (10) compensating for the internal conical shape, and facilitating use on a flat support.
  • Figure 2 shows an alternative embodiment.
  • the bottle has walls of substantially constant thickness.
  • the bottle also has a base (11) having a front section allowing connection with the bottom of the bottle. This base (11) ensures the stability of the bottle on a flat support.
  • Figure 3 shows another alternative embodiment.
  • the central part is extended by a cylindrical skirt (12) of a height at least equal to the height of the conical part of the bottom.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Packages (AREA)

Abstract

The invention concerns a flask specifically designed for packaging biological analysis reagents consisting of a hollow body sealed with a stopper, the bottom of the hollow body being concave.

Description

Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique et procédé de conditionnement de réactifs d'analyse biologique . Bottle intended specifically for packaging biological analysis reagents and method for packaging biological analysis reagents.

La présente invention concerne des flacons destinés spécifiquement au conditionnement de réactifs d'analyse biologique. Ces flacons sont dans l'état de la technique des flacons en verre ou en matière plastique présentant un volume intérieur cylindrique, à fond plat. Ces flacons sont souvent utilisés avec des automates de pipetage. Les réactifs d'analyse biologique sont des produits dont le prix peut être très élevé, et il est donc indispensable d'éviter toute perte de produit.The present invention relates to bottles intended specifically for packaging biological analysis reagents. These bottles are in the state of the art glass or plastic bottles having a cylindrical interior volume, with a flat bottom. These bottles are often used with pipetting machines. Biological analysis reagents are very expensive products, and it is therefore essential to avoid any loss of product.

Le but de la présente invention est de remédier aux inconvénients des flacons de l'état de la technique en proposant un flacon amélioré réduisant les pertes de produits, notamment des dernières gouttes de réactif. A cet effet, l'invention concerne de façon générale un flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique formé par un corps creux obturable par un bouchon caractérisé en ce que le fond du corps creux est de forme concave. Un tel fond permet une récupération de la totalité du réactif avec des pipettes, notamment avec des pipettes automatiques. Avantageusement, le fond du corps creux est de forme conique.The object of the present invention is to remedy the drawbacks of the bottles of the state of the art by proposing an improved bottle reducing the loss of products, in particular of the last drops of reagent. To this end, the invention relates generally to a bottle intended specifically for the packaging of biological analysis reagents formed by a hollow body closable by a stopper characterized in that the bottom of the hollow body is of concave shape. Such a bottom allows recovery of the entire reagent with pipettes, in particular with automatic pipettes. Advantageously, the bottom of the hollow body is of conical shape.

Selon un mode de réalisation préféré, la génératrice du fond forme un angle d'environ 30 degrés avec le plan perpendiculaire à l'axe du flacon.According to a preferred embodiment, the generator of the bottom forms an angle of about 30 degrees with the plane perpendicular to the axis of the bottle.

Selon une variante, le flacon présente des parois d'épaisseur sensiblement constante, le fond étant prolongé par une embase de stabilisation. Selon un premier mode de réalisation, flacon présente des parois minces prolongées à la partie inférieure par une jupe cylindrique.According to a variant, the bottle has walls of substantially constant thickness, the bottom being extended by a stabilization base. According to a first embodiment, the bottle has thin walls extended at the bottom by a cylindrical skirt.

Selon un autre mode de réalisation, le flacon présente un col raccordé à la partie centrale du corps creux par des parois coniques pour faciliter la récupération des condensats .According to another embodiment, the bottle has a neck connected to the central part of the hollow body by conical walls to facilitate the recovery of condensate.

Avantageusement, la section du col est inférieure à 0,6 fois la section du corps creux.Advantageously, the section of the neck is less than 0.6 times the section of the hollow body.

L'invention concerne également un procédé de conditionnement de réactifs d'analyse biologique caractérisé en ce qu'il sont stockés dans des flacons présentant un fond concave.The invention also relates to a method for packaging reagents for biological analysis, characterized in that they are stored in bottles having a concave bottom.

L'invention sera mieux comprise à la lecture de la description qui suit, faisant référence aux dessins annexés où :The invention will be better understood on reading the description which follows, referring to the accompanying drawings in which:

la figure 1 représente une vue en perspective d'un premier exemple de réalisation d'un flacon selon l'invention ;Figure 1 shows a perspective view of a first embodiment of a bottle according to the invention;

- la figure 2 représente une vue en perspective d'un deuxième exemple de réalisation d'un flacon selon l'invention ;- Figure 2 shows a perspective view of a second embodiment of a bottle according to the invention;

la figure 3 représente une vue en perspective d'un troisième exemple de réalisation d'un flacon selon l'invention.FIG. 3 represents a perspective view of a third embodiment of a bottle according to the invention.

La figure 1 représente une vue en perspective d'un premier exemple de réalisation d'un flacon selon l'invention. Il est constitué par un récipient, par exemple en matière plastique telle que le PET, et présente un volume intérieur creux dont la partie centrale (1) est cylindrique. La partie centrale (1) est prolongée vers le- bas par une partie coniqueFigure 1 shows a perspective view of a first embodiment of a bottle according to the invention. It consists of a container, for example made of plastic such as PET, and has a hollow interior volume, the central part (1) of which is cylindrical. The central part (1) is extended downwards by a conical part

(2) présentant une ouverture de l'ordre de 30° par rapport au plan horizontal (3) . Le fond présente une partie centrale (4) semi-sphérique , d'une section sensiblement égale à la section extérieure d'une pipette, facilitant le positionnement de la tête d'une pipette et la récupération des dernières quantités de réactifs .(2) having an opening of the order of 30 ° relative to the horizontal plane (3). The bottom has a semi-spherical central part (4), of a section substantially equal to the external section of a pipette, facilitating the positioning of the head of a pipette and the recovery of the last quantities of reagents.

La partie centrale est prolongée à l'extrémité opposée au fond (2) par une partie coniqueThe central part is extended at the end opposite the bottom (2) by a conical part

(5) se terminant par le col (6) . La partie conique (5) conduit à une réduction significative de la section, et présente des parois formant un angle de 30 à 45° avec le plan transversal. Cette partie conique (5) facilite la récupération des condensats et réduit la perte de produits par évaporâtion. Le col (6) présente à sa surface extérieure un filetage (7) apte à coopérer avec un bouchon vissable (8) connu en soi. Un joint d'étanchéité (9) peut être intercalé entre le col (6) et le bouchon (8) .(5) ending with the neck (6). The conical part (5) leads to a significant reduction in section, and has walls forming an angle of 30 to 45 ° with the transverse plane. This conical part (5) facilitates the recovery of condensates and reduces the loss of products by evaporation. The neck (6) has on its outer surface a thread (7) capable of cooperating with a screw cap (8) known per se. A seal (9) can be interposed between the neck (6) and the plug (8).

Le fond présente une surépaisseur (10) compensant la forme conique intérieure, et facilitant l'utilisation sur un support plan.The bottom has an extra thickness (10) compensating for the internal conical shape, and facilitating use on a flat support.

La figure 2 représente une variante de réalisation. Le flacon présente des parois d'épaisseur sensiblement constante. Pour compenser la forme conique du fond, le flacon comporte en outre une embase (11) présentant une section frontale permettant la liaison avec le fond du flacon. Cette embase (11) assure la stabilité du flacon sur un support plan.Figure 2 shows an alternative embodiment. The bottle has walls of substantially constant thickness. To compensate for the conical shape of the bottom, the bottle also has a base (11) having a front section allowing connection with the bottom of the bottle. This base (11) ensures the stability of the bottle on a flat support.

La figure 3 représente une autre variante de réalisation. Pour compenser la forme conique du fond (2), la partie centrale est prolongée par une jupe (12) cylindrique d'une hauteur au moins égale à la hauteur de la partie conique du fond.Figure 3 shows another alternative embodiment. To compensate for the conical shape of the bottom (2), the central part is extended by a cylindrical skirt (12) of a height at least equal to the height of the conical part of the bottom.

L'invention est décrite dans ce qui précède à titre d'exemple non limitatif. Il est entendu que l'homme du méti-er pourra réaliser différentes variantes de réalisation sans pour autant sortir du cadre deThe invention is described in the foregoing by way of nonlimiting example. It is understood that the skilled worker will be able to carry out different variant embodiments without going beyond the ambit of

] ' invention . ] 'invention.

Claims

R E V E N D I C A T I O N SR E V E N D I C A T I O N S 1 - Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique formé par un corps creux obturable par un bouchon, le fond du corps creux étant de forme concave, caractérisé en ce que la génératrice de fond forme un angle d'environ 30° avec le plan perpendiculaire à l'axe du flacon.1 - Bottle specifically intended for the packaging of biological analysis reagents formed by a hollow body closable by a stopper, the bottom of the hollow body being of concave shape, characterized in that the bottom generator forms an angle of approximately 30 ° with the plane perpendicular to the axis of the bottle. 2 - Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique selon l'une quelconque des revendications précédentes caractérisé en ce que le flacon présente des parois d'épaisseur sensiblement constante, le fond étant prolongé par une embase de stabilisation.2 - Bottle intended specifically for the packaging of biological analysis reagents according to any one of the preceding claims, characterized in that the bottle has walls of substantially constant thickness, the bottom being extended by a stabilization base. 3 - Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique selon l'une quelconque des revendications précédentes caractérisé en ce que le flacon présente des parois minces prolongées à la partie inférieure par une jupe cylindrique .3 - Bottle intended specifically for the packaging of biological analysis reagents according to any one of the preceding claims, characterized in that the bottle has thin walls extended at the bottom by a cylindrical skirt. 4 Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique selon 1 ' une quelconque des revendications précédentes caractérisé en ce qu'il présente une col raccordé à la partie centrale du corps creux par des parois coniques pour faciliter la récupération des condensats .4 bottle specifically intended for the packaging of biological analysis reagents according to any one of the preceding claims, characterized in that it has a neck connected to the central part of the hollow body by conical walls to facilitate the recovery of condensates. 5 - Flacon destiné spécifiquement au conditionnement de réactifs d'analyse biologique selon5 - Bottle specifically intended for the packaging of biological analysis reagents according to 1 ' une quelconque des revendications précédentes caractérisé en ce que la section du col est inférieure à 0,6 fois la section du corps creux. 6 - Procédé de condi ionnement de réactifs d'analyse biologique caractérisé en ce qu'il sont stockés dans des flacons présentant un fond concave.1 any one of the preceding claims characterized in that the section of the neck is less than 0.6 times the section of the hollow body. 6 - Process for conditioning biological analysis reagents, characterized in that they are stored in bottles having a concave bottom. 7 - Procédé de conditionnement de réactifs d'analyse biologique selon la revendication 8 caractérisé en ce qu'il sont stockés dans des flacons présentant un fond conique.7 - A method of conditioning biological analysis reagents according to claim 8 characterized in that they are stored in bottles having a conical bottom. 8 - Procédé de conditionnement de réactifs d'analyse biologique selon la revendication 8 ou 9 caractérisé en ce qu'il sont stockés dans des flacons présentant un col à section réduit raccordé à la partie médiane par des parois coniques . 8 - A method of conditioning biological analysis reagents according to claim 8 or 9 characterized in that they are stored in bottles having a neck with reduced section connected to the middle part by conical walls.
PCT/FR1998/000353 1997-02-25 1998-02-23 Flask specifically designed for packaging biological analysis reagents and method for packaging biological analysis reagents Ceased WO1998038095A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9702236A FR2759923B1 (en) 1997-02-25 1997-02-25 BOTTLE SPECIFICALLY FOR PACKAGING BIOLOGICAL ANALYSIS REAGENTS AND METHOD FOR PACKAGING BIOLOGICAL ANALYSIS REAGENTS
FR97/02236 1997-02-25

Publications (1)

Publication Number Publication Date
WO1998038095A1 true WO1998038095A1 (en) 1998-09-03

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ID=9504150

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1998/000353 Ceased WO1998038095A1 (en) 1997-02-25 1998-02-23 Flask specifically designed for packaging biological analysis reagents and method for packaging biological analysis reagents

Country Status (2)

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FR (1) FR2759923B1 (en)
WO (1) WO1998038095A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1308253B1 (en) * 1999-03-16 2001-12-10 Molteni L E C Dei Flii Alitti PRECISION DISPENSER FOR LIQUIDS.
FR2822804B1 (en) 2001-04-03 2004-06-04 Sidel Sa CONTAINER, ESPECIALLY BOTTLED, IN THERMOPLASTIC MATERIAL WHOSE BOTTOM HAS A CROSS FOOTPRINT
BRMU8500295Y1 (en) * 2005-02-23 2014-01-14 CONSTRUCTIVE PROVISION ON PACKAGING OF MEDICINAL PRODUCTS AND COSMETICS

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307764A1 (en) * 1982-03-06 1983-09-15 Olympus Optical Co., Inc., Tokyo Reagent vessel for a chemical analyser
US4880126A (en) * 1988-03-15 1989-11-14 Anderson Dennis C Nesting preventer for bottle bases
EP0387084A1 (en) * 1989-03-09 1990-09-12 Yoshino Kogyosho Co., Ltd. Bottle-shaped container with base cap
US5344036A (en) * 1992-06-04 1994-09-06 Akzo N.V. Container system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307764A1 (en) * 1982-03-06 1983-09-15 Olympus Optical Co., Inc., Tokyo Reagent vessel for a chemical analyser
US4880126A (en) * 1988-03-15 1989-11-14 Anderson Dennis C Nesting preventer for bottle bases
EP0387084A1 (en) * 1989-03-09 1990-09-12 Yoshino Kogyosho Co., Ltd. Bottle-shaped container with base cap
US5344036A (en) * 1992-06-04 1994-09-06 Akzo N.V. Container system

Also Published As

Publication number Publication date
FR2759923B1 (en) 1999-05-14
FR2759923A1 (en) 1998-08-28

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