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EP1280701B1 - Conditionneuse automatique pour produits pharmaceutiques solides - Google Patents

Conditionneuse automatique pour produits pharmaceutiques solides Download PDF

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Publication number
EP1280701B1
EP1280701B1 EP01924590A EP01924590A EP1280701B1 EP 1280701 B1 EP1280701 B1 EP 1280701B1 EP 01924590 A EP01924590 A EP 01924590A EP 01924590 A EP01924590 A EP 01924590A EP 1280701 B1 EP1280701 B1 EP 1280701B1
Authority
EP
European Patent Office
Prior art keywords
cavities
template
solid pharmaceutical
product package
pharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP01924590A
Other languages
German (de)
English (en)
Other versions
EP1280701A4 (fr
EP1280701A1 (fr
Inventor
Todd Siegel
Michael Stevenson
Stuart Bagley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MTS Medication Technologies Inc
Original Assignee
MTS Medication Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24152845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1280701(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/539,834 external-priority patent/US7185476B1/en
Application filed by MTS Medication Technologies Inc filed Critical MTS Medication Technologies Inc
Priority to EP06022295.7A priority Critical patent/EP1787909B1/fr
Publication of EP1280701A1 publication Critical patent/EP1280701A1/fr
Publication of EP1280701A4 publication Critical patent/EP1280701A4/fr
Application granted granted Critical
Publication of EP1280701B1 publication Critical patent/EP1280701B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/26—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for marking or coding completed packages

Definitions

  • the present invention relates generally to the field of automated pharmaceutical packaging machines. More specifically, the present invention is directed to an automated pharmaceutical packaging machine which simultaneously fills a product package template with desired solid pharmaceutical dosing requirements while also simultaneously sealing a final package containing a plurality of individual patient doses.
  • an automated pharmaceutical packaging machine which is capable of automatically selecting and depositing one or more solid pharmaceutical products into a plurality of medication packages for a patient while also simultaneously sealing and further processing a solid pharmaceutical product package.
  • US 4,655,026 discloses a pill dispensing machine which can selectively dispense a plurality of different medications into preformed recesses in a plastic strip.
  • the machine controls a plurality of dispensing devices to dispense into each of the recesses one or more pills associated with a particular time and date for administration.
  • the present invention overcomes the shortcomings of the prior art and provides a fully automated pharmaceutical product packaging machine which is capable of selectively depositing one or more different solid pharmaceutical products into an individual cavity for each of a plurality of individual patient product package cavities.
  • the system that is descried below is a fully automated machine which is computer controlled and employs a plurality of solid pharmaceutical product dispensing canisters. Each of these solid pharmaceutical dispensing canisters is capable of selectively dispensing a pre-designated number of solid pharmaceutical products.
  • the canisters are programmable and can be manipulated with a computer controller. These canisters are capable of selecting individual pills regardless of their size or shape and are commercially available.
  • the system of the present invention employs an array of canisters arranged within a mechanical feeding mechanism.
  • Each canister is designed to feed a funnel or trough which transmits a solid pharmaceutical product selectively dispensed from one of the canisters into a cavity of a product package template.
  • a plurality of pharmaceuticals may be selected for a single cavity member. This step is repeated for each of the plurality of cavities in template that corresponds with the cavities in a single sheet or card of cavities that provide a patient's dosing requirements for a given period of time.
  • a single sheet may typically include all of the solid pharmaceutical products that have been prescribed for a patient during a one week period.
  • the patient's doctor may have prescribed three or four different administration times during the week and accordingly the dosing card has typically between 21 and 28 different individual cavities.
  • Each of the cavities are capable of holding a volume of solid pharmaceuticals necessary for patient dosing requirements.
  • the clear plastic sheet of material is then maneuvered into subsequent product packaging stations and the template is returned to beneath the canister region.
  • the template member is selectively moveable through a range of motion defined by an X-Y axis so that each cavity of the template may be selectively positioned beneath the feed mechanism for transfer of pharmaceuticals located in the canisters.
  • the system then simultaneously fills the template with either the dosing requirements for the same patient for another week or the dosing requirements for another patient for a given period of time.
  • the sheet of clear plastic material now containing each of the solid pharmaceutical doses for the first patient are then simultaneously enclosed and packaged into a final package that may be given to a patient or the care givers for the patient so that the prescribed pharmaceuticals may be administered from the product package.
  • the machine saves a significant amount of time by simultaneously filling the template while also packaging the previously selected pharmaceuticals.
  • the present invention employs canisters which are commercially available for selectively for dispensing the desired quantity of solid pharmaceutical products.
  • a sheet of backing material is secured to the clear plastic members to enclose the pharmaceutical products within the clear plastic cavities as is known in the art.
  • the machine of the present invention makes use of pneumatically controlled automated machinery for packaging and manipulating the product. Additionally, the system of the present invention includes pharmaceutical product package and sealing stations.
  • FIG. 1 An embodiment of a fully automated pharmaceutical product packaging machine which is capable of selectively depositing one or more different solid pharmaceutical products into an individual cavity for each of a plurality of individual patient product package cavities is shown generally at 10 in Figure 1.
  • a computer 12 is linked with the various members of the system to control their respective operations.
  • the system employs a plurality of solid pharmaceutical product dispensing canisters each of which are mounted in a pharmaceutical dispensing mechanism 15.
  • the pharmaceutical dispensing canisters are commercially available products.
  • Each of the solid pharmaceutical dispensing canisters located within the pharmaceutical dispensing mechanism 15 is capable of selectively dispensing a pre-designated number of solid pharmaceutical products.
  • the canisters are each independently programmable and can be manipulated via the computer controller 12.
  • the canisters are capable of selecting individual pills regardless of their size or shape.
  • Each canister is arranged within the pharmaceutical dispensing mechanism to feed a funnel or trough which transmits a solid pharmaceutical product selectively dispensed from one or more of the canisters into a cavity of a product package template 17. This step is repeated for each of the plurality of cavities in the template 17 that corresponds with the cavities in a single sheet or card of cavities in a package that provide a patient's dosing requirements for a given period of time.
  • the template member 17 is selectively moveable through a range of motion defined by an X-Y axis so that each cavity of the template 17 may be selectively positioned beneath the feed mechanism of the pharmaceutical dispensing mechanism 15 for transfer of pharmaceuticals located in the canisters located therein.
  • the dispensing mechanism 15 has a plurality of canisters that are controlled by signals from the computer. Each of the canisters may have a separate address so that the canisters will only respond to commands intended for the selected canister.
  • Figure 1 also illustrates a cart 19 for convenient location of the computer controller 12.
  • the moveable cart 19 may also provide a location for a pneumatic drive generator that is used in driving the stations of the machine.
  • a package transfer track is shown at 22 and provides a mechanism for transferring a pharmaceutical product package 23 between each of the separate stations of the machine.
  • a lift mechanism 24 lifts and transfers filled pharmaceutical product packages 23 from the transfer track 22.
  • a product package dispensing unit is shown at 27 and transfers empty package members onto the transfer track 22.
  • the system of the present invention also includes a product package sealing station 30 and a printing station 32.
  • the product package dispensing unit 27 is shown adjacent the printing station 32. however, it is preferred that each package dispensing station be located adjacent or near the pharmaceutical product dispensing unit 15. This eliminates travel of the product package during the manufacturing process and also enables the filling of the pharmaceutical package template to take place simultaneously with sealing and/or further processing of another package member.
  • Each of the cavities of a pharmaceutical product package are capable of holding a volume of solid pharmaceuticals necessary for patient dosing requirements.
  • the template 17 containing temporary storage cavities for each combination of drugs has been filled, the template is automatically positioned over a portion of a pharmaceutical product package comprising a sheet of clear plastic material containing a plurality of cavities.
  • the cavities in the clear plastic material correspond to the cavities in the template.
  • a barrier between the cavities in the template 17 and the sheet of clear plastic material is moved when the desired number of cavities have been filled and the pharmaceuticals in the template cavities drop into the corresponding cavities in the clear plastic sheet of material.
  • the clear plastic sheet of material is then maneuvered adjacent to at least one package sealing member and the combined structure of the now filled plastic sheet and the sealing member is then transferred along transfer track 22 to the product package sealing station 30. While this occurs, the template 17 is returned to beneath the pharmaceutical dispensing mechanism 15.
  • the system 10 then simultaneously fills the template with either the dosing requirements for the same patient for another week or the dosing requirements for another patient for a given period of time. While the template 17 is being filled, the sheet of clear plastic material now containing each of the solid pharmaceutical doses for the first patient are then simultaneously enclosed and sealed by the sealing station 30 into a final package that may be given to a patient or the care givers for the patient so that the prescribed pharmaceuticals may be administered from the product package.
  • a sheet of backing material is secured to the clear plastic members to enclose the pharmaceutical products within the clear plastic cavities as is known in the art.
  • the machine saves a significant amount of time by simultaneously filling the template while also packaging the previously selected pharmaceuticals.
  • the machine of the present invention desirably makes use of pneumatically controlled automated machinery for packaging and manipulating the product, however, those skilled in the art will appreciate that the machine of the present invention may be powered by any conventional or future developed drive mechanism. For example stepping motors may be used for mechanical manipulation of various elements as described above.
  • Figure 2 illustrates a top plan view of the system described above with reference to Figure 1.
  • Figure 2 illustrates the relative spacing of the various manufacturing stations described above.
  • the empty product package dispensing station 27 actually be located adjacent the pharmaceutical dispensing station 15.
  • additional product package dispensing stations may be inserted between the sealing station 30 and the pharmaceutical dispensing mechanism depending on the number of distinct package elements that to be sealed together by the sealing station 30.
  • Figure 3 illustrates the pharmaceutical product dispensing unit 15 as well as the template member 17.
  • the pharmaceutical product dispensing unit 15 is supported by structural support members 36, 37, and 38.
  • Control lines 42 connect the canisters with the computer 12 so that the desired pharmaceuticals may be dispensed by the machine.
  • Figure 4 is a detailed view of the package sealing station 30.
  • the product package transfer track 22 passes directly beneath the sealing station 30.
  • the sealing station 30 may be comprised of any conventional sealing mechanism.
  • this sealing station 30 may be capable of applying heat or pressure or some type of electromagnetic radiation or combinations of these sealing techniques in order to set any adhesives that has been previously applied to the product packaging material.
  • One significant feature is that the relationship of these structures allows for simultaneously filling the product template while also sealing another filled package or otherwise further processing the package.
  • Figure 5 illustrates a conventional printing station that is mounted above the pharmaceutical product package transfer track 22.
  • This station prints information on the sealed product package which may relate to such things as identification of the patient, the time and dates for which the medication has been prescribed as well content information and/or expiration information.
  • this station is also capable of operating in parallel and independent from the pharmaceutical dispensing station 15.
  • FIG 6 illustrates the pharmaceutical product package dispensing station 27.
  • This station is also typical of known automated product package dispensing devices.
  • the station is desirably mounted adjacent the product package transfer track 22 so that product packages or partial packages may be readily placed on the track member 22. As noted it is preferred that one or more of these stations be located between the sealing station 30 and the dispensing station 15.
  • Figure 7 illustrates an automated device 24 which automatically removes the completed product packages from the transfer track 22.
  • Figure 7 also illustrates a completed package located on the transfer mechanism 42 which is mounted in the product package transfer track 22.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)

Claims (5)

  1. Procédé de remplissage d'emballages de produits pharmaceutiques solides (23), comprenant les étapes ci-dessous:
    distribution automatique et sélective d'un ou de plusieurs produits pharmaceutiques solides à partir de plusieurs sources de médicaments différentes (15) dans plusieurs cavités du gabarit d'emballage des produits (17) à travers un mécanisme d'alimentation commun en assurant un déplacement des cavités du gabarit de l'emballage de produits (17) dans deux directions de déplacement par rapport au mécanisme d'alimentation, de sorte que le mécanisme d'alimentation est sélectivement agencé au-dessus de l'une des cavités individuelles en vue de placer un ou plusieurs produits pharmaceutiques solides à partir des plusieurs sources de médicaments différentes (15) dans chacune desdites plusieurs cavités du gabarit (17), les deux direction de déplacement étant en général mutuellement perpendiculaires; et
    transfert automatique des produits pharmaceutiques solides placés dans les plusieurs cavités du gabarit de l'emballage des produits (17) dans des cavités correspondantes d'un emballage des produits pharmaceutiques (23).
  2. Procédé selon la revendication 1, comprenant en outre, au cours de ladite étape de distribution sélective des produits pharmaceutiques solides, l'étape de scellage simultané d'un autre emballage de produits pharmaceutiques (23) ayant été rempli auparavant d'une variété de produits pharmaceutiques solides.
  3. Procédé selon les revendications 1 ou 2, comprenant une étape d'impression d'informations sur un emballage de produits pharmaceutiques (23).
  4. Procédé selon les revendications 1 ou 2, comprenant en outre une étape de distribution, de façon au moins pratiquement simultanée, de premiers et deuxièmes produits pharmaceutiques à partir des première et deuxième cartouches dans une seule cavité du gabarit.
  5. Dispositif de remplissage d'emballages de produits pharmaceutiques solides (23), comprenant:
    (i) plusieurs sources de médicaments différentes:
    (ii) un mécanisme d'alimentation commun, en communication avec lesdites plusieurs sources de médicaments différentes;
    (iii) plusieurs cavités du gabarit de l'emballage des produis (17), dans lesquelles sont agencés un ou plusieurs produits pharmaceutiques solides en vue de leur distribution par le mécanisme d'alimentation;
    (iv) un moyen pour entraîner le déplacement des cavités du gabarit de l'emballage des produits (17) dans deux directions de déplacement par rapport au mécanisme d'alimentation, de sorte que le mécanisme d'alimentation est sélectivement agencé au-dessus des cavités individuelles, lesdites deux directions de déplacement étant en général mutuellement perpendiculaires; et
    (v) un moyen pour assurer le transfert automatique des produits pharmaceutiques solides placés dans lesdites plusieurs cavités de gabarit de l'emballage de produits (17) dans des cavités correspondantes d'un emballage de produits pharmaceutiques (23).
EP01924590A 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides Expired - Lifetime EP1280701B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06022295.7A EP1787909B1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/539,834 US7185476B1 (en) 1999-05-11 2000-03-31 Automated solid pharmaceutical product packaging machine
US539834 2000-03-31
PCT/US2001/010641 WO2001074666A1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP06022295.7A Division EP1787909B1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides

Publications (3)

Publication Number Publication Date
EP1280701A1 EP1280701A1 (fr) 2003-02-05
EP1280701A4 EP1280701A4 (fr) 2003-05-14
EP1280701B1 true EP1280701B1 (fr) 2007-05-09

Family

ID=24152845

Family Applications (2)

Application Number Title Priority Date Filing Date
EP06022295.7A Expired - Lifetime EP1787909B1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides
EP01924590A Expired - Lifetime EP1280701B1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP06022295.7A Expired - Lifetime EP1787909B1 (fr) 2000-03-31 2001-03-29 Conditionneuse automatique pour produits pharmaceutiques solides

Country Status (9)

Country Link
EP (2) EP1787909B1 (fr)
JP (1) JP4806153B2 (fr)
AT (1) ATE361876T1 (fr)
AU (2) AU5123501A (fr)
BR (1) BR0109719B1 (fr)
CA (1) CA2404589C (fr)
DE (1) DE60128348T2 (fr)
ES (2) ES2286116T3 (fr)
WO (1) WO2001074666A1 (fr)

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US7185476B1 (en) 1999-05-11 2007-03-06 Mts, Medication Technologies, Inc. Automated solid pharmaceutical product packaging machine
US6925774B2 (en) * 2000-03-31 2005-08-09 Mts Medication Technologies, Inc. Compact structure for automatically filling solid pharmaceutical product packages
DE102004020510B4 (de) * 2004-04-26 2007-11-29 Edwin Kohl Anlage zur Bestückung von Verpackungseinheiten mit dem verordnungsgemäßen Wochenbedarf von Patienten entsprechenden Medikamenten
DE102005049882B3 (de) * 2005-10-17 2007-02-01 Uhlmann Pac-Systeme Gmbh & Co. Kg. Vorrichtung zum geordneten Zuführen und Ablegen zu verpackender Kleinteile in die Näpfe einer Folienbahn
US7182105B1 (en) * 2005-11-08 2007-02-27 Mts Medication Technologies, Inc. Automated solid pharmaceutical packaging machine utilizing robotic drive
CA2662873C (fr) * 2006-09-11 2013-11-19 Synergie Medicale Brg Inc. Systeme et procede de distribution de medicaments
US7784244B2 (en) * 2007-08-13 2010-08-31 Mts Medication Technologies, Inc. High speed automated filling of solid pharmaceutical product packaging via a conveyor system
EP2062822A1 (fr) 2007-11-24 2009-05-27 UHLMANN PAC-SYSTEME GmbH & Co. KG Procédé et dispositif de remplissage individuel de blisters
CA2629916A1 (fr) * 2008-01-23 2009-07-23 Jvm Co., Ltd. Appareillage et methode permettant le conditionnement automatique d'emballage d'ordonnance et boite d'emballage d'ordonnance
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KR101006014B1 (ko) 2008-08-21 2011-01-06 (주)제이브이엠 호퍼 청소장치를 갖는 약제 자동 포장기
DE102008047975B4 (de) * 2008-09-18 2013-10-02 Sim Automation Gmbh & Co. Kg Vorrichtung zur individuellen Zusammenstellung von Tabletten
US10351285B2 (en) * 2014-11-04 2019-07-16 Mts Medication Technologies, Inc. Systems and methods for automatically verifying packaging of solid pharmaceuticals via robotic technology according to patient prescription data
US10179664B2 (en) 2014-11-05 2019-01-15 Mts Medication Technologies, Inc. Dispensing canisters for packaging oral solid pharmaceuticals via robotic technology according to patient prescription data
DE102019132870A1 (de) * 2019-12-03 2021-06-10 Gebr. Willach Gmbh Befüllvorrichtung für Verpackungen, Verpackungsvorrichtung sowie Verfahren zur Befüllung von Verpackungen
CN113492044B (zh) * 2021-07-21 2022-08-19 东莞市浩彩油墨科技有限公司 一种纳米可调色环保油墨生产研磨系统

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Also Published As

Publication number Publication date
CA2404589A1 (fr) 2001-10-11
ATE361876T1 (de) 2007-06-15
ES2286116T3 (es) 2007-12-01
DE60128348D1 (de) 2007-06-21
WO2001074666A1 (fr) 2001-10-11
CA2404589C (fr) 2009-08-18
EP1280701A4 (fr) 2003-05-14
EP1280701A1 (fr) 2003-02-05
ES2570739T3 (es) 2016-05-20
AU2001251235B2 (en) 2006-04-27
BR0109719B1 (pt) 2010-11-30
BR0109719A (pt) 2003-04-29
EP1787909A2 (fr) 2007-05-23
EP1787909B1 (fr) 2016-03-09
EP1787909A3 (fr) 2007-12-19
JP4806153B2 (ja) 2011-11-02
JP2003529498A (ja) 2003-10-07
DE60128348T2 (de) 2008-01-10
AU5123501A (en) 2001-10-15

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