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EP0561322A1 - Flacon compte-gouttes pour deux produits devant être mélangés avant usage - Google Patents

Flacon compte-gouttes pour deux produits devant être mélangés avant usage Download PDF

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Publication number
EP0561322A1
EP0561322A1 EP93104161A EP93104161A EP0561322A1 EP 0561322 A1 EP0561322 A1 EP 0561322A1 EP 93104161 A EP93104161 A EP 93104161A EP 93104161 A EP93104161 A EP 93104161A EP 0561322 A1 EP0561322 A1 EP 0561322A1
Authority
EP
European Patent Office
Prior art keywords
reservoir
cap
neck
ring
union
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP93104161A
Other languages
German (de)
English (en)
Other versions
EP0561322B1 (fr
Inventor
Evro Fabbri
Giovanni Ferrari
Antonio Fontana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lameplast SRL
Original Assignee
Lameplast SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lameplast SRL filed Critical Lameplast SRL
Publication of EP0561322A1 publication Critical patent/EP0561322A1/fr
Application granted granted Critical
Publication of EP0561322B1 publication Critical patent/EP0561322B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2814—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
    • B65D51/2842—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being provided with a preformed weakened line
    • B65D51/285—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being provided with a preformed weakened line ruptured by a sharp element, e.g. a cutter or a piercer

Definitions

  • the invention concerns a dropping bottle particularly for pharmaceutical products which, prior to use, are activated by being mixed together, namely, a deformable plastic container, generally containing a liquid substance, into which another, generally powdery, substance contained in a reservoir above is precipitated, following the partial thrust-shearing of the diaphragm forming the bottom of said reservoir by the lower cutting end of the dropper sliding inside the reservoir itself: the top end of said dropper being covered by a cap which also serves to apply down-thrust to the dropper; the liquid substance and the powdery one, or also two liquid substances, being of a medicinal or cosmetic nature.
  • the prior art comprises flexible bottles with a cylindrical reservoir open at the top, its lower extremity being anchored internally and externally to the neck of the bottle and its base consisting of a diaphragm shearing peripherally on thrust being applied to a rigid dropper having a chisel-shaped lower cutting-end and a top dispensing-end featuring a calibrated aperture and fitted with a cap that closes, protects and actuates and which forms a close, sliding fit on the outer cylindrical surface of said reservoir when actuated by pressure being applied to the top of said cap in order to shear said diaphragm and so cause the two substances to mix.
  • the invention resolves said technical problem by adopting a bottle surmounted by a reservoir having a base in the form of a diaphragm shearing as a result of down-thrust applied to the cap enclosing the top of the dropper, said dropper having a chisel-shaped lower cutting end, the casing of said cap extending towards the neck of the bottle in at least one continuous or sectional warranty seal, delimited by shear lines, as required, said casing having, at its lower extremity, a lip protruding inwards and lodging in a corresponding groove cut into the reservoir or into an external downwards extension of the same: the whole of the casing and the warranty seal being substantially continuous at least as far as the step at the top of the union square to the neck of the bottle; the presence of said seal preventing both the activation of mixing, in the case of down-thrust being applied to the cap, and the removal of said cap, given the impossibility of the cap's sliding axially when the warranty seal has not been torn off.
  • the advantages of the invention are: the impossibility of perforating the diaphragm without removing the warranty seal; the impossibility of sliding the cap off without removing the warranty seal and hence the impossibility of gaining access to the substance contained in the reservoir without leaving evidence of tampering, namely, the absence of the warranty seal and the presence of any separable lower remains of it.
  • Figure 1 is the enlarged axial section of the top part of the bottle, fitted with a mixing device with tamper-proof seal, in the embodiment wherein the lower end of the cap comprises a warranty seal with below it a separable annular element and with a union to the neck integral with the reservoir: the whole as it appears before use;
  • Figure 2 is a section as in Figure 1, but in the mixing phase prior to use;
  • Figure 3 is a part-sectional view of the whole of the element that actuates, protects and offers warranty and also serves as a plug;
  • Figure 4 is the cross-section IV-IV of Figure 3;
  • Figure 5 is a partial section of the rigid body of the dropper for dispensing measured drops having a funnel at the top and a perforator at the bottom;
  • Figure 6 is a partial section of the reservoir containing the substance to be fed into the body of the bottle below and mounted on the neck of said bottle;
  • Figure 7 is a partial section of the body, incomplete
  • the figures show: the body of the bottle 1, having a neck 2, for example with a lower locating ring 3 acting as an assembly bearing; one or more annular projections or threads 4 connecting with a union 5 having a watertight inner lip 6 of the hollow cylindrical body 7 of the dispenser of the substance, be it liquid, powder or solid, to be mixed with the liquid in the bottle below; a diaphragm 8 with a predetermined peripheral shear-line, supporting the substance contained in the chamber 9 of the reservoir 7; a hollow, cylindrical intermediate body 10 of the dropper, a bottom end being chisel-shaped so as to shear the diaphragm 8; an upper funnel 12 of the body 10, acting as a dropper; a ring 13 forming the outside edge of the funnel 12 to arrest the downstroke of the dropper once shearing is complete; an upper outer ring 14 and a lower ring 15 respectively of the hollow cylindrical body 10 of the dropper forming a watertight seal; a multi-function hollow cylindrical element 16, in the form of a cap
  • the separable lower annular section below the warranty seal is anchored to the body 7 of the reservoir ( Figures 1, 9); in the embodiment of Figure 8, the separable annular section of the warranty seal is anchored to the neck of the bottle 1; in the embodiment of Figure 10, said separable annular section is anchored under the bottom lip of the union 5 of the body 7 of the reservoir to the neck 2; in the embodiment of Figure 11, with said lower annular section missing, the warranty seal 33 is anchored to the body 7 of the reservoir.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP93104161A 1992-03-19 1993-03-15 Flacon compte-gouttes pour deux produits devant être mélangés avant usage Expired - Lifetime EP0561322B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMO920035A IT1259924B (it) 1992-03-19 1992-03-19 Flacone contagocce particolarmente per prodotti farmaceutici attivabili all'uso per miscelazione
ITMO920035 1992-03-19

Publications (2)

Publication Number Publication Date
EP0561322A1 true EP0561322A1 (fr) 1993-09-22
EP0561322B1 EP0561322B1 (fr) 1996-10-23

Family

ID=11385168

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93104161A Expired - Lifetime EP0561322B1 (fr) 1992-03-19 1993-03-15 Flacon compte-gouttes pour deux produits devant être mélangés avant usage

Country Status (4)

Country Link
EP (1) EP0561322B1 (fr)
DE (1) DE69305553T2 (fr)
ES (1) ES2096788T3 (fr)
IT (1) IT1259924B (fr)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0577200A1 (fr) * 1992-07-02 1994-01-05 Laboratorios Cusi, S.A. Récipient pour produits pharmaceutiques à deux composants séparés, comprenant un dispositif de mélange, et de distribution dosée
ES2064277A1 (es) * 1993-03-30 1995-01-16 Cusi Lab Contenedor de productos farmaceuticos, con dos sustancias separadas y dispositivo de mezcla y dispensado dosificado.
EP0778221A1 (fr) * 1995-12-04 1997-06-11 Laboratorios Cusi, S.A. Récipient pour produits pharmaceutiques comprenant deux composants séparés et dispositif de mélange, ainsi que la distribution dosée et procédé d'assemblage de ce récipient
EP0921079A1 (fr) * 1997-12-02 1999-06-09 Plastikwerk Expan GesmbH Récipient à deux compartiments
WO1999039987A1 (fr) 1998-02-09 1999-08-12 Tengiz Kekelidze Bouchons
WO2001005675A1 (fr) 1999-07-19 2001-01-25 Societe Des Produits Nestle S.A. Ensemble destine a deux produits a melanger juste avant l'emploi
GB2365405A (en) * 2000-08-01 2002-02-20 Lily Hsu A container and closure assembly with multiple storage compartments
AT410085B (de) * 1997-12-02 2003-01-27 Feichtinger Ernst Expan Behälter
WO2004031048A1 (fr) * 2002-10-04 2004-04-15 Sheldon Denholm Tree Dispositif distributeur de liquide
EP1087894A4 (fr) * 1998-03-20 2004-12-01 Seaquist Closures Structure distributrice a membrane frangible separant deux produits
WO2005044430A3 (fr) * 2003-11-10 2005-08-04 Jeong-Min Lee Procede et structure permettant de melanger differentes matieres dans un recipient souple
WO2005087606A1 (fr) * 2004-03-09 2005-09-22 Wendon Limited Distributeur volumetrique
US7114403B2 (en) 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
EP1687217A4 (fr) * 2003-11-05 2006-11-02 Jeong-Min Lee Procede et appareil permettant de melanger des matieres differentes
US7210575B2 (en) 2002-09-26 2007-05-01 Boehringer Ingelheim International Gmbh Two-component packaging unit
US7544324B2 (en) 2003-11-14 2009-06-09 Oakville Hong Kong Company Limited Rapid sample analysis storage devices and methods of use
DE102008000802A1 (de) 2008-03-20 2009-10-08 Faurecia Innenraum Systeme Gmbh Vollautomatisches Staufach
WO2010019096A1 (fr) * 2008-08-11 2010-02-18 Astrazeneca Ab Insert pré-rempli formant récipient pour mélanger au moins deux ingrédients à utiliser dans un système de récipients pharmaceutiques
WO2011060456A1 (fr) * 2009-11-10 2011-05-19 Ewan Dirk Kromhout Accessoire pour un contenant
US8071394B2 (en) 2006-07-26 2011-12-06 Alere Switzerland Gmbh Test device for detecting an analyte in a liquid sample
ITMO20100326A1 (it) * 2010-11-12 2012-05-13 Punto Pack S R L Capsula perfezionata per sostanze da miscelare al momento dell'uso.
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
ITUB20159655A1 (it) * 2015-12-23 2017-06-23 Bormioli Rocco Spa Capsula di sicurezza di un contenitore.
IT201600080494A1 (it) * 2016-08-01 2018-02-01 Lameplast Spa Confezione per prodotti a preparazione estemporanea, particolarmente medicinali, farmaceutici, cosmetici o simili

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10640275B2 (en) 2017-06-12 2020-05-05 Bio-Techne Corportion Dual chamber storage device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3802604A (en) * 1972-02-28 1974-04-09 Oreal Device for storing two products separately and dispensing them simultaneously
EP0093090A2 (fr) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. Fermeture pour bouteilles comprenant un récipient cassable
EP0217425A1 (fr) * 1985-08-02 1987-04-08 ZAMBON S.p.A. Ensemble comportant un couvercle, un réservoir et un compte-goutte pour bouteilles
EP0344849A2 (fr) * 1988-06-01 1989-12-06 Dam Technological Research Ltd. Capuchon de récipient pour poudres

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3802604A (en) * 1972-02-28 1974-04-09 Oreal Device for storing two products separately and dispensing them simultaneously
EP0093090A2 (fr) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. Fermeture pour bouteilles comprenant un récipient cassable
EP0217425A1 (fr) * 1985-08-02 1987-04-08 ZAMBON S.p.A. Ensemble comportant un couvercle, un réservoir et un compte-goutte pour bouteilles
EP0344849A2 (fr) * 1988-06-01 1989-12-06 Dam Technological Research Ltd. Capuchon de récipient pour poudres

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0577200A1 (fr) * 1992-07-02 1994-01-05 Laboratorios Cusi, S.A. Récipient pour produits pharmaceutiques à deux composants séparés, comprenant un dispositif de mélange, et de distribution dosée
US5474209A (en) * 1992-07-02 1995-12-12 Laboratorios Cusi, S.A. Pharmaceutical product container with two separate substances and a mixing device and dosed dispensation
ES2064277A1 (es) * 1993-03-30 1995-01-16 Cusi Lab Contenedor de productos farmaceuticos, con dos sustancias separadas y dispositivo de mezcla y dispensado dosificado.
AU711119B2 (en) * 1995-12-04 1999-10-07 Laboratorios Cusi, S.A. Pharmaceutical container for two separate substances, incorporating a mixing device for dosed application, and an assembly process thereof
ES2128220A1 (es) * 1995-12-04 1999-05-01 Cusi Lab Envase farmaceutico de dos sustancias separadas, con dispositivo de mezcla, aplicacion dosificada y su proceso de montaje.
JPH09154918A (ja) * 1995-12-04 1997-06-17 Lab Cusi Sa ２種の分離した物質を含有する医薬品容器およびその組み立て方法
EP0778221A1 (fr) * 1995-12-04 1997-06-11 Laboratorios Cusi, S.A. Récipient pour produits pharmaceutiques comprenant deux composants séparés et dispositif de mélange, ainsi que la distribution dosée et procédé d'assemblage de ce récipient
CN1127332C (zh) * 1995-12-04 2003-11-12 库西实验室有限公司 具有混合装置的分装两物质的配量施药容器及其装配方法
AT410085B (de) * 1997-12-02 2003-01-27 Feichtinger Ernst Expan Behälter
EP0921079A1 (fr) * 1997-12-02 1999-06-09 Plastikwerk Expan GesmbH Récipient à deux compartiments
US6073803A (en) * 1997-12-02 2000-06-13 Plastikwerk Expan Gmbh Container
WO1999039987A1 (fr) 1998-02-09 1999-08-12 Tengiz Kekelidze Bouchons
EP1087894A4 (fr) * 1998-03-20 2004-12-01 Seaquist Closures Structure distributrice a membrane frangible separant deux produits
EP1072530A1 (fr) 1999-07-19 2001-01-31 Société des Produits Nestlé S.A. Ensemble pour deux produits devant être mélangés juste avant l'emploi
WO2001005675A1 (fr) 1999-07-19 2001-01-25 Societe Des Produits Nestle S.A. Ensemble destine a deux produits a melanger juste avant l'emploi
GB2365405A (en) * 2000-08-01 2002-02-20 Lily Hsu A container and closure assembly with multiple storage compartments
GB2365405B (en) * 2000-08-01 2004-03-10 Lily Hsu Container with separate storage spaces
US7210575B2 (en) 2002-09-26 2007-05-01 Boehringer Ingelheim International Gmbh Two-component packaging unit
WO2004031048A1 (fr) * 2002-10-04 2004-04-15 Sheldon Denholm Tree Dispositif distributeur de liquide
US7114403B2 (en) 2003-05-30 2006-10-03 Oakville Hong Kong Co., Ltd Fluid collection and application device and methods of use of same
EP1687217A4 (fr) * 2003-11-05 2006-11-02 Jeong-Min Lee Procede et appareil permettant de melanger des matieres differentes
WO2005044430A3 (fr) * 2003-11-10 2005-08-04 Jeong-Min Lee Procede et structure permettant de melanger differentes matieres dans un recipient souple
US7617929B2 (en) 2003-11-10 2009-11-17 Lee Jeong-Min Method and structure for mixing different materials in a pouch container
US7544324B2 (en) 2003-11-14 2009-06-09 Oakville Hong Kong Company Limited Rapid sample analysis storage devices and methods of use
US7837939B2 (en) 2003-11-14 2010-11-23 Alere Switzerland Gmbh Rapid sample collection and analysis device and methods of use
US7490719B2 (en) 2004-03-09 2009-02-17 Wendon Limited Volumetric dispenser
WO2005087606A1 (fr) * 2004-03-09 2005-09-22 Wendon Limited Distributeur volumetrique
US8871155B2 (en) 2005-11-30 2014-10-28 Alere Switzerland Gmbh Devices for detecting analytes in fluid sample
US8071394B2 (en) 2006-07-26 2011-12-06 Alere Switzerland Gmbh Test device for detecting an analyte in a liquid sample
DE102008000802A1 (de) 2008-03-20 2009-10-08 Faurecia Innenraum Systeme Gmbh Vollautomatisches Staufach
AU2009280391B2 (en) * 2008-08-11 2012-05-31 Astrazeneca Ab A pre-filled container insert for mixing two or more ingredients for use in a pharmaceutical container system
WO2010019096A1 (fr) * 2008-08-11 2010-02-18 Astrazeneca Ab Insert pré-rempli formant récipient pour mélanger au moins deux ingrédients à utiliser dans un système de récipients pharmaceutiques
WO2011060456A1 (fr) * 2009-11-10 2011-05-19 Ewan Dirk Kromhout Accessoire pour un contenant
ITMO20100326A1 (it) * 2010-11-12 2012-05-13 Punto Pack S R L Capsula perfezionata per sostanze da miscelare al momento dell'uso.
WO2012063140A1 (fr) * 2010-11-12 2012-05-18 Punto Pack S.R.L. Capsule améliorée pour des substances à mélanger au moment de l'utilisation
ITUB20159655A1 (it) * 2015-12-23 2017-06-23 Bormioli Rocco Spa Capsula di sicurezza di un contenitore.
WO2017109599A1 (fr) * 2015-12-23 2017-06-29 Bormioli Rocco S.P.A. Capsule de sécurité pour un récipient
US10882672B2 (en) 2015-12-23 2021-01-05 Bormioli Pharma S.p.A. Safety capsule for a container
US11535434B2 (en) 2015-12-23 2022-12-27 Bormioli Pharma S.p.A. Safety capsule for a container
IT201600080494A1 (it) * 2016-08-01 2018-02-01 Lameplast Spa Confezione per prodotti a preparazione estemporanea, particolarmente medicinali, farmaceutici, cosmetici o simili
WO2018025162A1 (fr) * 2016-08-01 2018-02-08 Lameplast S.P.A. Emballage pour produits à préparation extemporanés, en particulier des produits médicaux, pharmaceutiques, cosmétiques ou similaires
US20190177057A1 (en) * 2016-08-01 2019-06-13 Lameplast S.P.A. Packaging for extemporaneous preparation products, particularly medicinal, pharmaceutical, cosmetic products or the like

Also Published As

Publication number Publication date
IT1259924B (it) 1996-03-28
DE69305553D1 (de) 1996-11-28
ES2096788T3 (es) 1997-03-16
ITMO920035A0 (it) 1992-03-19
ITMO920035A1 (it) 1993-09-19
DE69305553T2 (de) 1997-05-28
EP0561322B1 (fr) 1996-10-23

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