EP0460064A4 - Therapeutic aerosol formulations - Google Patents

Therapeutic aerosol formulations

Info

Publication number: EP0460064A4
Authority: EP; European Patent Office
Prior art keywords: aerosol formulations; therapeutic aerosol; therapeutic; formulations; aerosol
Prior art date: 1989-02-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19900904101

Other languages

English (en)

Other versions

EP0460064A1 (fr

Inventor

George Robert 1485 Ashford Avenue Felt

Mark Peter Warchol

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Rorer International Holdings Inc

Original Assignee

Rorer International Holdings Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1990-02-21

Publication date

1992-04-01

1990-02-21 Application filed by Rorer International Holdings Inc filed Critical Rorer International Holdings Inc

1991-12-11 Publication of EP0460064A1 publication Critical patent/EP0460064A1/fr

1992-04-01 Publication of EP0460064A4 publication Critical patent/EP0460064A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP19900904101 1989-02-23 1990-02-21 Therapeutic aerosol formulations Withdrawn EP0460064A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US31460589A	1989-02-23	1989-02-23
US314605		1989-02-23

Publications (2)

Publication Number	Publication Date
EP0460064A1 EP0460064A1 (fr)	1991-12-11
EP0460064A4 true EP0460064A4 (en)	1992-04-01

Family

ID=23220626

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19900904101 Withdrawn EP0460064A4 (en)	1989-02-23	1990-02-21	Therapeutic aerosol formulations

Country Status (6)

Country	Link
EP (1)	EP0460064A4 (fr)
JP (1)	JPH05508616A (fr)
AU (1)	AU5194990A (fr)
CA (1)	CA2050905A1 (fr)
FI (1)	FI913899A7 (fr)
WO (1)	WO1990009781A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0562125A4 (fr) *	1991-10-11	1994-03-18	Toray Industries	Composition a base d'anticorps.
ATE146359T1 (de) *	1992-01-21	1997-01-15	Stanford Res Inst Int	Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln
US6582728B1 (en)	1992-07-08	2003-06-24	Inhale Therapeutic Systems, Inc.	Spray drying of macromolecules to produce inhaleable dry powders
US5698672A (en) *	1995-04-04	1997-12-16	Zymogenetics, Inc.	Synthetic calcitonin mimetics
GB9612297D0 (en) *	1996-06-11	1996-08-14	Minnesota Mining & Mfg	Medicinal aerosol formulations
DE19733651A1 (de) *	1997-08-04	1999-02-18	Boehringer Ingelheim Pharma	Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole
GB9807232D0 (en) *	1998-04-03	1998-06-03	Univ Cardiff	Aerosol composition
US6458338B1 (en) *	1998-09-22	2002-10-01	Aeropharm Technology Incorporated	Amino acid stabilized medicinal aerosol formulations
US6136294C1 (en) *	1998-09-22	2002-09-24	Aeropharm Technology Inc	Amino acid stabilized medical aerosol formulation
US6540983B1 (en)	2000-01-25	2003-04-01	Aeropharm Technology Incorporated	Medical aerosol formulation
US6540982B1 (en)	2000-01-25	2003-04-01	Aeropharm Technology Incorporated	Medical aerosol formulation
US6585957B1 (en)	2000-01-25	2003-07-01	Aeropharm Technology Incorporated	Medicinal aerosol formulation
US6468507B1 (en)	2000-05-01	2002-10-22	Aeropharm Technology, Inc.	Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer
US6548049B1 (en)	2000-05-01	2003-04-15	Aeropharm Technology Incorporated	Medicinal aerosol formulation
US6464959B1 (en)	2000-05-01	2002-10-15	Aeropharm Technology Incorporated	Non-aqueous aerosol suspension comprising troglitazone, a fluid propellant, and an amino acid stabilizer
US6565833B1 (en)	2000-05-01	2003-05-20	Aeropharm Technology Incorporated	Medicinal aerosol formulation
US6749845B2 (en)	2001-02-15	2004-06-15	Aeropharm Technology, Inc.	Modulated release particles for lung delivery
US7176278B2 (en)	2001-08-30	2007-02-13	Biorexis Technology, Inc.	Modified transferrin fusion proteins
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP2176251B1 (fr)	2007-07-21	2012-02-08	Albany Molecular Research, Inc.	Indazoles substitués par la 5-pyridinone et compositions pharmaceutiques les contenant
EP2222639A1 (fr)	2007-11-21	2010-09-01	Decode Genetics EHF	Inhibiteurs de biaryle pde4 pour le traitement de troubles pulmonaires et cardiovasculaires
EP2077132A1 (fr)	2008-01-02	2009-07-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
EP2240481A1 (fr)	2008-01-11	2010-10-20	Albany Molecular Research, Inc.	Pyridoindoles (1-azinone)-substitués en tant qu'antagonistes mch
US8297305B2 (en)	2008-01-28	2012-10-30	Kohler Co.	Valve assembly having an improved flow path
WO2010059836A1 (fr)	2008-11-20	2010-05-27	Decode Genetics Ehf	Composés bicycliques substitués à pont aza pour maladie cardiovasculaire et du système nerveux central
CN102361876B (zh)	2009-01-26	2015-02-04	以色列生物研究所	二环杂环螺环化合物
US10011906B2 (en)	2009-03-31	2018-07-03	Beohringer Ingelheim International Gmbh	Method for coating a surface of a component
US9265910B2 (en)	2009-05-18	2016-02-23	Boehringer Ingelheim International Gmbh	Adapter, inhalation device, and nebulizer
WO2011064163A1 (fr)	2009-11-25	2011-06-03	Boehringer Ingelheim International Gmbh	Nébuliseur
AP3141A (en)	2009-11-25	2015-02-28	Boehringer Ingelheim Int	Nebulizer
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
US9943654B2 (en)	2010-06-24	2018-04-17	Boehringer Ingelheim International Gmbh	Nebulizer
WO2012130757A1 (fr)	2011-04-01	2012-10-04	Boehringer Ingelheim International Gmbh	Appareil médical pourvu d'un récipient
US9827384B2 (en)	2011-05-23	2017-11-28	Boehringer Ingelheim International Gmbh	Nebulizer
WO2013152894A1 (fr)	2012-04-13	2013-10-17	Boehringer Ingelheim International Gmbh	Pulvérisateur comprenant des moyens de détrompage
JP6643231B2 (ja)	2013-08-09	2020-02-12	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
EP2835146B1 (fr)	2013-08-09	2020-09-30	Boehringer Ingelheim International GmbH	Atomiseur
EP3139984B1 (fr)	2014-05-07	2021-04-28	Boehringer Ingelheim International GmbH	Nébuliseur
DK3139979T3 (da)	2014-05-07	2023-10-09	Boehringer Ingelheim Int	Enhed, forstøver og fremgangsmåde
CN106456913B (zh)	2014-05-07	2019-08-30	勃林格殷格翰国际有限公司	喷雾器和容器
WO2019183245A1 (fr)	2018-03-20	2019-09-26	Icahn School Of Medicine At Mount Sinai	Composés inhibiteurs de kinase, compositions et procédés d'utilisation
WO2020049505A1 (fr)	2018-09-06	2020-03-12	Innopharmascreen Inc.	Procédés et compositions pour le traitement de l'asthme ou de la maladie de parkinson
AU2019419414A1 (en)	2018-12-31	2023-04-06	Icahn School Of Medicine At Mount Sinai	Kinase inhibitor compounds and compositions and methods of use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB837465A (en) *	1957-01-31	1960-06-15	Riker Laboratories Inc	Self-propelling, powder-dispensing compositions
GB994734A (en) *	1962-10-30	1965-06-10	Riker Laboratories Inc	Self-propelling powder-dispensing compositions
EP0302772A1 (fr) *	1987-08-03	1989-02-08	Asahi Kasei Kogyo Kabushiki Kaisha	Calcitonin pour administration nasale

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4241051A (en) *	1977-11-04	1980-12-23	Christie Robert B	Calcitonin
JPS61267528A (ja) *	1984-11-26	1986-11-27	Yamanouchi Pharmaceut Co Ltd	吸収促進剤を含有するカルシトニン経鼻剤
ATE78158T1 (de) *	1985-05-22	1992-08-15	Liposome Technology Inc	Verfahren und system zum einatmen von liposomen.
NL8602950A (nl) *	1985-12-04	1987-07-01	Sandoz Ag	Calcitonine-derivaten en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten.

1990
- 1990-02-21 CA CA002050905A patent/CA2050905A1/fr not_active Abandoned
- 1990-02-21 FI FI913899A patent/FI913899A7/fi not_active Application Discontinuation
- 1990-02-21 EP EP19900904101 patent/EP0460064A4/en not_active Withdrawn
- 1990-02-21 WO PCT/US1990/000928 patent/WO1990009781A1/fr not_active Ceased
- 1990-02-21 JP JP90504385A patent/JPH05508616A/ja active Pending
- 1990-02-21 AU AU51949/90A patent/AU5194990A/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB837465A (en) *	1957-01-31	1960-06-15	Riker Laboratories Inc	Self-propelling, powder-dispensing compositions
GB994734A (en) *	1962-10-30	1965-06-10	Riker Laboratories Inc	Self-propelling powder-dispensing compositions
EP0302772A1 (fr) *	1987-08-03	1989-02-08	Asahi Kasei Kogyo Kabushiki Kaisha	Calcitonin pour administration nasale

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
K. PARKITT et al.: "MARTINDALE - THE EXTRA PHARMACOPOEIA", Twenty-ninth edition, edited by J.E.F. Reynolds, January 1989, The Pharmaceutical Press, London, GB; *
PATENT ABSTRACTS OF JAPAN, vol. 9, no. 331 (C-321)(2054), 25th December 1985; & JP-A-60 161 924 (FUJISAWA YAKUHIN KOGYO K.K.) 23-08-1985 *
See also references of WO9009781A1 *

Also Published As

Publication number	Publication date
WO1990009781A1 (fr)	1990-09-07
FI913899A0 (fi)	1991-08-19
JPH05508616A (ja)	1993-12-02
FI913899A7 (fi)	1991-08-19
CA2050905A1 (fr)	1990-08-24
EP0460064A1 (fr)	1991-12-11
AU5194990A (en)	1990-09-26

Publication	Publication Date	Title
EP0460064A4 (en)	1992-04-01	Therapeutic aerosol formulations
GB8921222D0 (en)	1989-11-08	Medicinal aerosol formulations
GB8828477D0 (en)	1989-01-05	Medical aerosol formulations
ZA914957B (en)	1992-04-29	Aerosol drug formulations
GB8822857D0 (en)	1988-11-02	Pharmaceutical formulations
GB8908250D0 (en)	1989-05-24	Formulations
GB9118830D0 (en)	1991-10-16	Medical aerosol formulations
ZA902519B (en)	1991-12-24	Pharmaceutical formulations
AP9000174A0 (en)	1990-04-30	Antiparasitical formulations
GB8920348D0 (en)	1989-10-25	Medicinal aerosol formulations
GB8802391D0 (en)	1988-03-02	Medicinal formulations
IE894215L (en)	1990-06-30	Pharmaceutical formulations
GB8918809D0 (en)	1989-09-27	Pharmaceutical formulations
GB8919456D0 (en)	1989-10-11	Pharmaceutical formulations
GB8926946D0 (en)	1990-01-17	Pharmaceutical formulations
GB8919597D0 (en)	1989-10-11	Pharmaceutical formulations
GB8919595D0 (en)	1989-10-11	Pharmaceutical formulations
GB8925529D0 (en)	1990-01-04	Therapeutic formulation
GB8925530D0 (en)	1990-01-04	Therapeutic formulation
GB8925531D0 (en)	1990-01-04	Therapeutic formulation
GB8925533D0 (en)	1990-01-04	Therapeutic formulation
GB8914790D0 (en)	1989-08-16	Formulations
GB8926129D0 (en)	1990-01-10	Formulations
IE894052L (en)	1990-06-16	Formulations
GB8924635D0 (en)	1989-12-20	Formulations

Legal Events

Date	Code	Title	Description
1991-10-25	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1991-12-11	17P	Request for examination filed	Effective date: 19910819
1991-12-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE
1992-04-01	A4	Supplementary search report drawn up and despatched	Effective date: 19920211
1992-04-01	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB IT LI LU NL SE
1993-02-24	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
1993-03-24	17Q	First examination report despatched	Effective date: 19930209
1993-04-14	18W	Application withdrawn	Withdrawal date: 19930215