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EE9900535A - Fumaarhappe derivaatide kasutamine - Google Patents

Fumaarhappe derivaatide kasutamine

Info

Publication number
EE9900535A
EE9900535A EEP199900535A EEP9900535A EE9900535A EE 9900535 A EE9900535 A EE 9900535A EE P199900535 A EEP199900535 A EE P199900535A EE P9900535 A EEP9900535 A EE P9900535A EE 9900535 A EE9900535 A EE 9900535A
Authority
EE
Estonia
Prior art keywords
fumaric acid
acid derivatives
administration
salts
alone
Prior art date
Application number
EEP199900535A
Other languages
English (en)
Inventor
K. Joshi Rajendra
Strebel Hans-Peter
Original Assignee
Fumapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fumapharm Ag filed Critical Fumapharm Ag
Publication of EE9900535A publication Critical patent/EE9900535A/et
Publication of EE03999B1 publication Critical patent/EE03999B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/593—Dicarboxylic acid esters having only one carbon-to-carbon double bond
    • C07C69/60—Maleic acid esters; Fumaric acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP199900535A 1997-05-20 1998-04-01 Fumaarhappe derivaatide kasutamine EE03999B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19721099A DE19721099C2 (de) 1997-05-20 1997-05-20 Verwendung von Fumarsäurederivaten
PCT/EP1998/001894 WO1998052549A2 (de) 1997-05-20 1998-04-01 Verwendung von fumarsäurederivaten

Publications (2)

Publication Number Publication Date
EE9900535A true EE9900535A (et) 2000-06-15
EE03999B1 EE03999B1 (et) 2003-04-15

Family

ID=7829995

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900535A EE03999B1 (et) 1997-05-20 1998-04-01 Fumaarhappe derivaatide kasutamine

Country Status (24)

Country Link
US (1) US6436992B1 (et)
EP (1) EP0980242B1 (et)
JP (1) JP3881038B2 (et)
CN (1) CN1153569C (et)
AT (1) ATE232093T1 (et)
AU (1) AU730441B2 (et)
BG (1) BG64613B1 (et)
BR (1) BR9809655A (et)
CA (1) CA2248955C (et)
CZ (1) CZ299960B6 (et)
DE (2) DE19721099C2 (et)
DK (1) DK0980242T3 (et)
EE (1) EE03999B1 (et)
ES (1) ES2190588T3 (et)
HU (1) HU227697B1 (et)
IL (1) IL132819A (et)
NO (1) NO326815B1 (et)
NZ (1) NZ501755A (et)
PL (1) PL190864B1 (et)
RS (1) RS49654B (et)
RU (1) RU2197963C2 (et)
SK (1) SK285897B6 (et)
TR (1) TR199902587T2 (et)
WO (1) WO1998052549A2 (et)

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DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
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DE10217314A1 (de) * 2002-04-18 2003-11-13 Fumapharm Ag Muri Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere
ATE380027T1 (de) 2003-09-09 2007-12-15 Fumapharm Ag Verwendung von fumarsäure-derivaten zur behandlung von herzinsuffizienz und asthma
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SI2533634T1 (sl) 2010-02-12 2016-01-29 Biogen Ma Inc. Nevroprotekcija pri demielinizacijskih boleznih
SG195049A1 (en) * 2011-05-26 2013-12-30 Biogen Idec Inc Methods of treating multiple sclerosis and preserving and/or increasing myelin content
NZ618178A (en) 2011-06-08 2016-03-31 Biogen Ma Inc Process for preparing high purity and crystalline dimethyl fumarate
EP2782561A1 (en) 2011-11-24 2014-10-01 Synthon BV Controlled release particles comprising dimethyl fumarate
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BR112014019480A8 (pt) 2012-02-07 2017-07-11 Xenoport Inc Composto fumarato de morfolinoalquila,composição farmacêutica,e,uso dos mesmos
WO2013119677A1 (en) 2012-02-07 2013-08-15 Biogen Idec Ma Inc. Pharmaceutical compositions containing dimethyl fumarate
US20140056973A1 (en) 2012-08-22 2014-02-27 Xenoport, Inc. Oral Dosage Forms Having a High Loading of a Methyl Hydrogen Fumarate Prodrug
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HK1253050A1 (zh) * 2015-02-02 2019-06-06 英仕柏集团有限责任公司 稳定的富马酸二烷基酯组合物
UA121323C2 (uk) 2015-02-08 2020-05-12 Алкермес Фарма Айрленд Лімітед Композиції на основі проліків монометилфумарату
MA41785A (fr) 2015-03-20 2018-01-23 Biogen Ma Inc Procédés et compositions pour l'administration intraveineuse de fumarates pour le traitement de maladies neurologiques
ES2826825T3 (es) 2015-03-27 2021-05-19 Symbionyx Pharmaceuticals Inc Composiciones y métodos para el tratamiento de la psoriasis
US10213411B2 (en) 2015-08-27 2019-02-26 Vijaykumar Rajasekhar Use of prodrugs of fumarates in treating heart failure diseases
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WO2017137576A1 (en) * 2016-02-12 2017-08-17 Universität Zürich Dimethyl fumarate (dmf) for prevention or treatment of gout, acne, diabetes, vitiligo and/or pyoderma gangrenosum
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Also Published As

Publication number Publication date
HUP0001684A2 (hu) 2000-09-28
CA2248955A1 (en) 1997-05-20
YU57599A (sh) 2001-12-26
DK0980242T3 (da) 2003-04-14
EP0980242A2 (de) 2000-02-23
US6436992B1 (en) 2002-08-20
DE19721099A1 (de) 1998-11-26
RU2197963C2 (ru) 2003-02-10
SK285897B6 (sk) 2007-10-04
ATE232093T1 (de) 2003-02-15
DE19721099C2 (de) 1999-12-02
JP2000513023A (ja) 2000-10-03
BG64613B1 (bg) 2005-09-30
CZ299960B6 (cs) 2009-01-07
SK41599A3 (en) 2000-12-11
RS49654B (sr) 2007-09-21
WO1998052549A2 (de) 1998-11-26
PL190864B1 (pl) 2006-02-28
EE03999B1 (et) 2003-04-15
CA2248955C (en) 2001-08-14
DE59807122D1 (de) 2003-03-13
NZ501755A (en) 2001-07-27
IL132819A (en) 2004-12-15
NO991342L (no) 1999-11-16
CN1153569C (zh) 2004-06-16
CZ108099A3 (cs) 1999-08-11
TR199902587T2 (xx) 2000-08-21
HK1027512A1 (en) 2001-01-19
HUP0001684A3 (en) 2001-09-28
ES2190588T3 (es) 2003-08-01
NO326815B1 (no) 2009-02-23
CN1257426A (zh) 2000-06-21
BG103335A (en) 2000-04-28
JP3881038B2 (ja) 2007-02-14
PL335381A1 (en) 2000-04-25
HU227697B1 (en) 2011-12-28
WO1998052549B1 (de) 1999-05-14
BR9809655A (pt) 2000-07-11
AU730441B2 (en) 2001-03-08
NO991342D0 (no) 1999-03-19
EP0980242B1 (de) 2003-02-05
WO1998052549A3 (de) 1999-04-08
AU7213698A (en) 1998-12-11
IL132819A0 (en) 2001-03-19

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