EE200200342A - Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend - Google Patents

Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend

Info

Publication number: EE200200342A
Authority: EE; Estonia
Prior art keywords: arylquinolines; substituted; pharmaceutical composition; precursor compound; precursor
Prior art date: 1999-12-22

Application number

EEP200200342A

Other languages

English (en)

Inventor

Deschenes Denis

Dube Daniel

Gallant Michel

Girard Yves

Lacombe Patrick

Macdonald Dwight

Mastracchio Anthony

Perrier Helene

Original Assignee

Merck Frosst Canada & Co.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-22

Filing date

2000-12-20

Publication date

2003-06-16

2000-12-20 Application filed by Merck Frosst Canada & Co. filed Critical Merck Frosst Canada & Co.

2003-06-16 Publication of EE200200342A publication Critical patent/EE200200342A/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EEP200200342A 1999-12-22 2000-12-20 Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend EE200200342A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17152299P	1999-12-22	1999-12-22
PCT/CA2000/001559 WO2001046151A1 (en)	1999-12-22	2000-12-20	Substituted 8-arylquinoline phosphodiesterase-4 inhibitors

Publications (1)

Publication Number	Publication Date
EE200200342A true EE200200342A (et)	2003-06-16

Family

ID=22624050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200342A EE200200342A (et)	1999-12-22	2000-12-20	Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend

Country Status (31)

Country	Link
EP (1)	EP1244628A1 (et)
JP (1)	JP3782011B2 (et)
KR (1)	KR20020082839A (et)
CN (1)	CN1221534C (et)
AR (1)	AR029214A1 (et)
AU (1)	AU778531B2 (et)
BG (1)	BG65403B1 (et)
BR (1)	BR0016651A (et)
CA (1)	CA2393749C (et)
CO (1)	CO5261613A1 (et)
CZ (1)	CZ20022171A3 (et)
DZ (1)	DZ3244A1 (et)
EA (1)	EA004747B1 (et)
EE (1)	EE200200342A (et)
GE (1)	GEP20053626B (et)
HR (1)	HRP20020545A2 (et)
HU (1)	HUP0203896A3 (et)
IL (1)	IL150114A0 (et)
IS (1)	IS6413A (et)
MX (1)	MXPA02006329A (et)
MY (1)	MY134008A (et)
NO (1)	NO20023013L (et)
NZ (1)	NZ520258A (et)
PE (1)	PE20010989A1 (et)
PL (1)	PL355752A1 (et)
SK (1)	SK8972002A3 (et)
TW (1)	TWI280240B (et)
UA (1)	UA74815C2 (et)
WO (1)	WO2001046151A1 (et)
YU (1)	YU47102A (et)
ZA (1)	ZA200204862B (et)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7776315B2 (en)	2000-10-31	2010-08-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical compositions based on anticholinergics and additional active ingredients
DE10110772A1 (de) *	2001-03-07	2002-09-12	Boehringer Ingelheim Pharma	Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
ES2242787T3 (es)	2000-12-20	2005-11-16	MERCK & CO., INC.	Procedimiento para preparar bencenosulfonatos de 8-arilquinolinio sustituidos.
US6740666B2 (en) *	2000-12-20	2004-05-25	Merck & Co., Inc.	Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
ES2242036T3 (es) *	2001-06-27	2005-11-01	MERCK FROSST CANADA & CO.	Inhibidores pde4 de arilquinolina 8-sustituida.
WO2003010137A1 (en) *	2001-07-24	2003-02-06	Merck & Co., Inc.	Preparation of sulfonyl quinoline
US20050014762A1 (en) *	2001-09-19	2005-01-20	Rolf Beume	Combination
AU2003209896A1 (en) *	2002-03-18	2003-09-29	Merck Frosst Canada And Co.	Hetero-bridge substituted 8-arylquinoline pde4 inhibitors
MXPA05009434A (es) *	2003-03-05	2005-11-23	Celgene Corp	Compuestos de difeniletileno y usos de los mismos.
CA2560895A1 (en) *	2004-03-25	2005-10-06	Synta Pharmaceuticals Corp.	Acrylonitrile derivatives for inflammation and immune-related uses
AU2006248200A1 (en) *	2005-05-19	2006-11-23	Synergenz Bioscience Limited	Methods and compositions for assessment of pulmonary function and disorders
RS53084B (sr)	2006-07-05	2014-06-30	Takeda Gmbh	Kombinacija inhibitora hmg-coa reduktaze rosuvastatina sa inhibitorom fosfodiesteraze 4, kao što je roflumilast, roflumilast-n-oksid za lečenje inflamatornih plućnih obolenja
MX2009000148A (es) *	2006-07-07	2009-10-26	Kalypsys Inc	Inhibidores heteroaril biciclicos de fosfodiesterasa 4.
AU2007299726A1 (en) *	2006-09-22	2008-03-27	Braincells, Inc.	Combination comprising an HMG-COA reductase inhibitor and a second neurogenic agent for treating a nervous system disorder and increasing neurogenesis
CA2676715A1 (en)	2007-02-12	2008-08-21	Merck & Co., Inc.	Piperazine derivatives for treatment of ad and related conditions
EP2291181B9 (en)	2008-04-18	2013-09-11	University College Dublin National University Of Ireland, Dublin	Captodiamine for the treatment of depression symptoms
WO2011099305A1 (en)	2010-02-12	2011-08-18	Raqualia Pharma Inc.	5-ht4 receptor agonists for the treatment of dementia
EP2741777B1 (en)	2011-08-12	2017-01-18	INSERM - Institut National de la Santé et de la Recherche Médicale	Methods and pharmaceutical compositions for treatment of pulmonary hypertension
WO2013054153A1 (en)	2011-10-11	2013-04-18	INSERM (Institut National de la Santé et de la Recherche Médicale)	Nutlin compounds for use in he treatment of pulmonary hypertension
EP3676262A4 (en)	2017-09-03	2021-03-31	Angion Biomedica Corp.	VINYLHETEROCYCLENE AS RHO-ASSOCIATED COILED COIL KINASE (ROCK) INHIBITORS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9226830D0 (en) *	1992-12-23	1993-02-17	Celltech Ltd	Chemical compounds
US5455252A (en) *	1993-03-31	1995-10-03	Syntex (U.S.A.) Inc.	Optionally substituted 6,8-quinolines
US6245774B1 (en) *	1994-06-21	2001-06-12	Celltech Therapeutics Limited	Tri-substituted phenyl or pyridine derivatives
JPH11209350A (ja) *	1998-01-26	1999-08-03	Eisai Co Ltd	含窒素複素環誘導体およびその医薬

2000
- 2000-12-19 MY MYPI20005965A patent/MY134008A/en unknown
- 2000-12-20 UA UA2002076108A patent/UA74815C2/uk unknown
- 2000-12-20 SK SK897-2002A patent/SK8972002A3/sk not_active Application Discontinuation
- 2000-12-20 EA EA200200702A patent/EA004747B1/ru not_active IP Right Cessation
- 2000-12-20 JP JP2001547062A patent/JP3782011B2/ja not_active Expired - Fee Related
- 2000-12-20 NZ NZ520258A patent/NZ520258A/en unknown
- 2000-12-20 KR KR1020027008079A patent/KR20020082839A/ko not_active Ceased
- 2000-12-20 AU AU23362/01A patent/AU778531B2/en not_active Ceased
- 2000-12-20 IL IL15011400A patent/IL150114A0/xx unknown
- 2000-12-20 CN CNB00818951XA patent/CN1221534C/zh not_active Expired - Fee Related
- 2000-12-20 HR HR20020545A patent/HRP20020545A2/hr not_active Application Discontinuation
- 2000-12-20 EP EP00986937A patent/EP1244628A1/en not_active Withdrawn
- 2000-12-20 EE EEP200200342A patent/EE200200342A/et unknown
- 2000-12-20 CZ CZ20022171A patent/CZ20022171A3/cs unknown
- 2000-12-20 WO PCT/CA2000/001559 patent/WO2001046151A1/en not_active Ceased
- 2000-12-20 DZ DZ003244A patent/DZ3244A1/fr active
- 2000-12-20 MX MXPA02006329A patent/MXPA02006329A/es not_active Application Discontinuation
- 2000-12-20 PL PL00355752A patent/PL355752A1/xx not_active IP Right Cessation
- 2000-12-20 BR BR0016651-0A patent/BR0016651A/pt not_active IP Right Cessation
- 2000-12-20 YU YU47102A patent/YU47102A/sh unknown
- 2000-12-20 GE GE4903A patent/GEP20053626B/en unknown
- 2000-12-20 CO CO00096650A patent/CO5261613A1/es not_active Application Discontinuation
- 2000-12-20 HU HU0203896A patent/HUP0203896A3/hu unknown
- 2000-12-20 CA CA002393749A patent/CA2393749C/en not_active Expired - Fee Related
- 2000-12-21 AR ARP000106867A patent/AR029214A1/es not_active Application Discontinuation
- 2000-12-21 TW TW089127506A patent/TWI280240B/zh not_active IP Right Cessation
- 2000-12-22 PE PE2000001396A patent/PE20010989A1/es not_active Application Discontinuation
2002
- 2002-06-11 IS IS6413A patent/IS6413A/is unknown
- 2002-06-18 ZA ZA200204862A patent/ZA200204862B/en unknown
- 2002-06-19 BG BG106840A patent/BG65403B1/bg unknown
- 2002-06-21 NO NO20023013A patent/NO20023013L/no unknown

Also Published As

Publication number	Publication date
BR0016651A (pt)	2002-09-10
IS6413A (is)	2002-06-11
KR20020082839A (ko)	2002-10-31
HRP20020545A2 (en)	2005-10-31
DZ3244A1 (fr)	2001-06-28
SK8972002A3 (en)	2002-11-06
JP3782011B2 (ja)	2006-06-07
WO2001046151A1 (en)	2001-06-28
MXPA02006329A (es)	2004-05-14
GEP20053626B (en)	2005-10-10
AU778531B2 (en)	2004-12-09
CN1221534C (zh)	2005-10-05
HUP0203896A2 (hu)	2003-04-28
EA004747B1 (ru)	2004-08-26
NZ520258A (en)	2004-05-28
HUP0203896A3 (en)	2003-05-28
NO20023013L (no)	2002-08-22
CA2393749C (en)	2008-06-17
PL355752A1 (en)	2004-05-17
EA200200702A1 (ru)	2003-02-27
TWI280240B (en)	2007-05-01
CO5261613A1 (es)	2003-03-31
IL150114A0 (en)	2002-12-01
AU2336201A (en)	2001-07-03
AR029214A1 (es)	2003-06-18
BG106840A (en)	2003-01-31
CA2393749A1 (en)	2001-06-28
BG65403B1 (bg)	2008-06-30
YU47102A (sh)	2005-06-10
CN1434801A (zh)	2003-08-06
PE20010989A1 (es)	2001-10-01
NO20023013D0 (no)	2002-06-21
CZ20022171A3 (cs)	2002-11-13
EP1244628A1 (en)	2002-10-02
ZA200204862B (en)	2003-03-17
MY134008A (en)	2007-11-30
JP2003531112A (ja)	2003-10-21
HK1057560A1 (en)	2004-04-08
UA74815C2 (en)	2006-02-15

Publication	Publication Date	Title
EE200000468A (et)	2002-04-15	Ühendid, nende kasutamine ja farmatseutiline kompositsioon
FI991485L (fi)	2000-12-31	Uusi farmaseuttinen koostumus
EE200200342A (et)	2003-06-16	Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend
EE200100391A (et)	2002-10-15	Peptidüül-heterotsüklilised ketoonid, nende kasutamine ja farmatseutiline kompositsioon
EE04464B1 (et)	2005-04-15	Indalüülasendatud benseenkarboksamiidid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
NO20015175L (no)	2001-10-23	Farmasöytisk sammensetning
EE200100594A (et)	2003-02-17	Uudsed ravimikompositsioonid, mis põhinevad antikolinergiliselt toimivatel ühenditel ja ß-mimeetikumidel
EE200200487A (et)	2004-02-16	Asetidiini derivaadid, nende valmistamismeetodid ja farmatseutiline kompositsioon
EE200200175A (et)	2003-04-15	Asendatud 2-tio-3,5-ditsüano-4-arüül-6-aminopüridiinid ja nende kasutamine
EE05183B1 (et)	2009-06-15	Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon
TR200003788A3 (tr)	2001-07-23	Yavas salimli oral dozaj bilesim.
EE200200064A (et)	2003-04-15	Arüülmetüülkarbonüülaminotiasooli derivaadid, nende valmistamine ja kasutamine vähivastaste toimeainetena
EE200300327A (et)	2003-10-15	Uurea derivaadid, nende valmistamismeetodid, kasutamine ja farmatseutiline kompositsioon
DK1204410T3 (da)	2012-10-29	Farmaceutisk doseringsform med flere komponenter
EE04236B1 (et)	2004-02-16	Bensimidasoolid, nende valmistamine ja kasutamineravimitena
ID27415A (id)	2001-04-05	Komposisi farmaseutik
EE200200149A (et)	2003-04-15	Kinasoliinühendid ja neid sisaldavad ravimkoostised
TR200003787A3 (tr)	2001-07-23	Kararli yavas salimli oral dozaj bilesimi.
EE200000621A (et)	2002-06-17	Pikornaviirusevastased ühendid, nende valmistamine ja kasutamine
ID29149A (id)	2001-08-02	Komposisi adjuvan
ID29262A (id)	2001-08-16	Komposisi farmasi
EE04497B1 (et)	2005-06-15	Püridopüranoasepiini derivaadid, nende valmistamine ja terapeutiline kasutamine
EE200100653A (et)	2003-02-17	Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine
ID27201A (id)	2001-03-08	Komposisi farmasi
EE200000651A (et)	2002-04-15	Asoolid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon

Legal Events

Date	Code	Title	Description
2003-12-15	HB1A	Correction of owner name or address
2006-04-17	GB1A	Change in the ownership or in the address of the owner