EE200000391A - Triasiiniühendid kesknärvisüsteemihäirete raviks - Google Patents
Triasiiniühendid kesknärvisüsteemihäirete raviksInfo
- Publication number
- EE200000391A EE200000391A EEP200000391A EEP200000391A EE200000391A EE 200000391 A EE200000391 A EE 200000391A EE P200000391 A EEP200000391 A EE P200000391A EE P200000391 A EEP200000391 A EE P200000391A EE 200000391 A EE200000391 A EE 200000391A
- Authority
- EE
- Estonia
- Prior art keywords
- treatment
- nervous system
- central nervous
- system disorders
- triazine compounds
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- 150000003918 triazines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9726987.2A GB9726987D0 (en) | 1997-12-22 | 1997-12-22 | Compounds |
| PCT/EP1998/008273 WO1999032462A1 (en) | 1997-12-22 | 1998-12-18 | Triazine compounds for treatment of cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200000391A true EE200000391A (et) | 2002-02-15 |
Family
ID=10823992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200000391A EE200000391A (et) | 1997-12-22 | 1998-12-18 | Triasiiniühendid kesknärvisüsteemihäirete raviks |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6265405B1 (et) |
| EP (1) | EP1042304A1 (et) |
| JP (1) | JP2001526275A (et) |
| KR (1) | KR20010024800A (et) |
| CN (1) | CN1284951A (et) |
| AP (1) | AP2000001846A0 (et) |
| AR (1) | AR014146A1 (et) |
| AU (1) | AU753874B2 (et) |
| BR (1) | BR9814495A (et) |
| CA (1) | CA2315620A1 (et) |
| CO (1) | CO5011066A1 (et) |
| EA (1) | EA200000561A1 (et) |
| EE (1) | EE200000391A (et) |
| GB (1) | GB9726987D0 (et) |
| GT (1) | GT199800203A (et) |
| HN (1) | HN1998000193A (et) |
| HR (1) | HRP20000419A2 (et) |
| HU (1) | HUP0100611A3 (et) |
| ID (1) | ID25449A (et) |
| IL (1) | IL136867A0 (et) |
| IS (1) | IS5542A (et) |
| JO (1) | JO2065B1 (et) |
| MA (1) | MA26587A1 (et) |
| NO (1) | NO20003211L (et) |
| NZ (1) | NZ505254A (et) |
| PA (1) | PA8465101A1 (et) |
| PE (1) | PE20000063A1 (et) |
| PL (1) | PL341392A1 (et) |
| SK (1) | SK9592000A3 (et) |
| SV (1) | SV1998000151A (et) |
| TR (1) | TR200001970T2 (et) |
| WO (1) | WO1999032462A1 (et) |
| YU (1) | YU39600A (et) |
| ZA (1) | ZA9811725B (et) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0002666D0 (en) | 2000-02-04 | 2000-03-29 | Univ London | Blockade of voltage dependent sodium channels |
| WO2003057219A1 (en) * | 2001-12-27 | 2003-07-17 | Ortho-Mcneil Pharmaceutical Inc. | Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder |
| ES2323268T3 (es) * | 2002-07-29 | 2009-07-10 | Glaxo Group Ltd | Formulaciones de liberacion prolongada que contienen lamotrigina. |
| US20040213842A1 (en) * | 2003-01-30 | 2004-10-28 | Dynogen Pharmaceuticals, Inc. | Methods of treating gastrointestinal tract disorders using sodium channel modulators |
| AR044503A1 (es) | 2003-03-18 | 2005-09-14 | Merck & Co Inc | Triazoles sustituidos con biarilo como bloqueantes del canal de sodio |
| DE10332472A1 (de) * | 2003-07-16 | 2005-02-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung von Tinnitus |
| PT1658062E (pt) * | 2003-08-25 | 2010-03-31 | Newron Pharm Spa | Derivados de alfa-amino amida úteis como agentes antiinflamatórios |
| US20060115865A1 (en) * | 2004-10-25 | 2006-06-01 | Anlong Ouyang | Lamotrigine analogs |
| GB201111712D0 (en) | 2011-07-08 | 2011-08-24 | Gosforth Ct Holdings Pty Ltd | Pharmaceutical compositions |
| TWI651310B (zh) | 2014-02-20 | 2019-02-21 | 日商日本煙草產業股份有限公司 | 三化合物及其醫藥用途 |
| CN108137515B (zh) | 2015-08-17 | 2021-07-06 | 日本烟草产业株式会社 | 羟基三嗪化合物和其医药用途 |
| ES2770143T3 (es) * | 2018-02-13 | 2020-06-30 | Fis Fabbrica Italiana Sintetici Spa | Nuevo procedimiento eficiente para la preparación de sitagliptina |
| CN114796146B (zh) * | 2022-04-28 | 2023-03-28 | 上海奥科达医药科技股份有限公司 | 一种拉莫三嗪的缓释制剂及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3637688A (en) | 1970-01-09 | 1972-01-25 | American Home Prod | 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines |
| IL60201A (en) | 1979-06-01 | 1984-05-31 | Wellcome Found | 3-amino-6-(substituted)phenyl-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing them |
| DE3062603D1 (en) | 1979-06-01 | 1983-05-11 | Wellcome Found | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
| EP0024351B1 (en) | 1979-08-16 | 1984-10-31 | The Wellcome Foundation Limited | Solid pharmaceutical formulation containing substitued phenyl-triazines |
| GB8328757D0 (en) | 1983-10-27 | 1983-11-30 | Wellcome Found | Chemical compounds |
| GB9012312D0 (en) | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| GB9012311D0 (en) | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| GB9012316D0 (en) | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| GB9203483D0 (en) | 1992-02-19 | 1992-04-08 | Wellcome Found | Anti-inflammatory compounds |
| ES2097516T3 (es) | 1992-06-12 | 1997-04-01 | Wellcome Found | Uso de isetionato de 3,5-diamino-6-(2,3-diclorofenil)-1,2,4-triazina para el tratamiento y prevencion de la dependencia, tolerancia y sensibilidad a los farmacos y drogas. |
| JPH08504798A (ja) | 1992-12-18 | 1996-05-21 | ザ ウエルカム ファウンデーション リミテッド | 酵素阻害薬としての，ピリミジン，ピリジン，プテリジノンおよびインダゾール誘導体 |
| GB9305692D0 (en) | 1993-03-19 | 1993-05-05 | Wellcome Found | Therapeutic triazine compounds and use |
| US5866597A (en) | 1993-03-19 | 1999-02-02 | Glaxo Wellcome Inc. | Use of triazine compounds for the treatment of memory and learning disorders |
| GB9426448D0 (en) * | 1994-12-30 | 1995-03-01 | Wellcome Found | Process |
| FR2741879A1 (fr) | 1995-12-05 | 1997-06-06 | Esteve Labor Dr | Derives de fluorophenyl-triazines et pyrimidines, leur preparation et leur application en tant que medicament |
-
1997
- 1997-12-22 GB GBGB9726987.2A patent/GB9726987D0/en not_active Ceased
-
1998
- 1998-12-18 WO PCT/EP1998/008273 patent/WO1999032462A1/en not_active Ceased
- 1998-12-18 US US09/582,058 patent/US6265405B1/en not_active Expired - Fee Related
- 1998-12-18 AR ARP980106526A patent/AR014146A1/es not_active Application Discontinuation
- 1998-12-18 JP JP2000525399A patent/JP2001526275A/ja active Pending
- 1998-12-18 EA EA200000561A patent/EA200000561A1/ru unknown
- 1998-12-18 EE EEP200000391A patent/EE200000391A/et unknown
- 1998-12-18 PL PL98341392A patent/PL341392A1/xx unknown
- 1998-12-18 IL IL13686798A patent/IL136867A0/xx unknown
- 1998-12-18 CA CA002315620A patent/CA2315620A1/en not_active Abandoned
- 1998-12-18 ID IDW20001416A patent/ID25449A/id unknown
- 1998-12-18 AU AU24147/99A patent/AU753874B2/en not_active Ceased
- 1998-12-18 SV SV1998000151A patent/SV1998000151A/es unknown
- 1998-12-18 AP APAP/P/2000/001846A patent/AP2000001846A0/en unknown
- 1998-12-18 YU YU39600A patent/YU39600A/sh unknown
- 1998-12-18 TR TR2000/01970T patent/TR200001970T2/xx unknown
- 1998-12-18 EP EP98966635A patent/EP1042304A1/en not_active Withdrawn
- 1998-12-18 KR KR1020007006947A patent/KR20010024800A/ko not_active Withdrawn
- 1998-12-18 CO CO98075403A patent/CO5011066A1/es unknown
- 1998-12-18 HU HU0100611A patent/HUP0100611A3/hu unknown
- 1998-12-18 BR BR9814495-2A patent/BR9814495A/pt not_active IP Right Cessation
- 1998-12-18 NZ NZ505254A patent/NZ505254A/en unknown
- 1998-12-18 HR HR20000419A patent/HRP20000419A2/hr not_active Application Discontinuation
- 1998-12-18 SK SK959-2000A patent/SK9592000A3/sk unknown
- 1998-12-18 CN CN98813745A patent/CN1284951A/zh active Pending
- 1998-12-21 PA PA19988465101A patent/PA8465101A1/es unknown
- 1998-12-21 PE PE1998001255A patent/PE20000063A1/es not_active Application Discontinuation
- 1998-12-21 JO JO19982065A patent/JO2065B1/en active
- 1998-12-21 ZA ZA9811725A patent/ZA9811725B/xx unknown
- 1998-12-22 MA MA25403A patent/MA26587A1/fr unknown
- 1998-12-22 GT GT199800203A patent/GT199800203A/es unknown
-
1999
- 1999-12-21 HN HN1998000193A patent/HN1998000193A/es unknown
-
2000
- 2000-06-20 IS IS5542A patent/IS5542A/is unknown
- 2000-06-21 NO NO20003211A patent/NO20003211L/no unknown
-
2001
- 2001-07-06 US US09/899,198 patent/US6465461B1/en not_active Expired - Fee Related
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