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ECSP13012489A - Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones - Google Patents

Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones

Info

Publication number
ECSP13012489A
ECSP13012489A ECSP13012489A ECSP13012489A EC SP13012489 A ECSP13012489 A EC SP13012489A EC SP13012489 A ECSP13012489 A EC SP13012489A EC SP13012489 A ECSP13012489 A EC SP13012489A
Authority
EC
Ecuador
Prior art keywords
dihydrobenzoxatiazepinas
derivatives
compositions
new
preparation procedure
Prior art date
Application number
Other languages
English (en)
Inventor
Patrice Desos
Alexis Cordi
Pierre Lestage
Laurence Danober
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43067253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012489(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of ECSP13012489A publication Critical patent/ECSP13012489A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D291/00Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/08Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D419/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Compuestos de fórmula (I) :en la queR1 representa un átomo de hidrógeno, un grupo heterocíclico, ciano, alcoxicarbonilo, alquilsulfonilaminoalquilo o N-hidroxicarboximidamida.Medicamentos.
ECSP13012489 2010-09-16 2013-03-15 Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones ECSP13012489A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1003683A FR2964969B1 (fr) 2010-09-16 2010-09-16 Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ECSP13012489A true ECSP13012489A (es) 2013-04-30

Family

ID=43067253

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012489 ECSP13012489A (es) 2010-09-16 2013-03-15 Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones

Country Status (41)

Country Link
US (1) US8569285B2 (es)
EP (1) EP2431360B1 (es)
JP (1) JP2013537216A (es)
KR (1) KR20130054438A (es)
CN (1) CN103153973A (es)
AP (1) AP2013006793A0 (es)
AR (1) AR082973A1 (es)
AU (1) AU2011213898A1 (es)
BR (1) BR112013005967A2 (es)
CA (1) CA2752131C (es)
CL (1) CL2013000655A1 (es)
CO (1) CO6680709A2 (es)
CR (1) CR20130105A (es)
CU (1) CU20130037A7 (es)
CY (1) CY1114110T1 (es)
DK (1) DK2431360T3 (es)
EA (1) EA201300340A1 (es)
EC (1) ECSP13012489A (es)
ES (1) ES2421504T3 (es)
FR (1) FR2964969B1 (es)
GE (1) GEP20156247B (es)
GT (1) GT201300067A (es)
HR (1) HRP20130505T1 (es)
IL (1) IL225209A0 (es)
MA (1) MA34529B1 (es)
ME (1) ME01524B (es)
MX (1) MX2013002892A (es)
NI (1) NI201300028A (es)
PE (1) PE20131342A1 (es)
PH (1) PH12013500423A1 (es)
PL (1) PL2431360T3 (es)
PT (1) PT2431360E (es)
RS (1) RS52835B (es)
SA (1) SA111320755B1 (es)
SG (1) SG188380A1 (es)
SI (1) SI2431360T1 (es)
TW (1) TWI421080B (es)
UA (1) UA105320C2 (es)
UY (1) UY33574A (es)
WO (1) WO2012035216A1 (es)
ZA (1) ZA201106353B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途
CN111559990B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种小分子噁噻嗪类衍生物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL137720A0 (en) * 1998-02-18 2001-10-31 Neurosearch As Compounds and their use as positive ampa receptor modulators
TWI232863B (en) * 2001-06-11 2005-05-21 Akzo Nobel Nv Benzoxazepine derivatives
MXPA03011562A (es) * 2001-06-14 2004-03-18 Akzo Nobel Nv Derivados de (pirido/tieno)-(f)-oxazepin-5-ona como moduladores positivos del receptor ampa.
FR2856064B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
CR20130105A (es) 2013-05-16
IL225209A0 (en) 2013-06-27
AR082973A1 (es) 2013-01-23
JP2013537216A (ja) 2013-09-30
AP2013006793A0 (en) 2013-04-30
CL2013000655A1 (es) 2013-08-09
TW201212921A (en) 2012-04-01
EP2431360A1 (fr) 2012-03-21
FR2964969A1 (fr) 2012-03-23
CO6680709A2 (es) 2013-05-31
FR2964969B1 (fr) 2012-08-24
PE20131342A1 (es) 2013-11-28
SA111320755B1 (ar) 2013-11-10
MA34529B1 (fr) 2013-09-02
TWI421080B (zh) 2014-01-01
HRP20130505T1 (hr) 2013-07-31
EP2431360B1 (fr) 2013-04-17
CU20130037A7 (es) 2013-05-31
PL2431360T3 (pl) 2013-08-30
BR112013005967A2 (pt) 2016-05-03
DK2431360T3 (da) 2013-07-22
CA2752131A1 (fr) 2012-03-16
UA105320C2 (ru) 2014-04-25
UY33574A (es) 2012-03-30
SI2431360T1 (sl) 2013-07-31
GEP20156247B (en) 2015-02-10
NI201300028A (es) 2014-01-07
RS52835B (sr) 2013-10-31
US20120071462A1 (en) 2012-03-22
PH12013500423A1 (en) 2017-08-23
CN103153973A (zh) 2013-06-12
GT201300067A (es) 2014-07-08
ME01524B (me) 2014-04-20
SG188380A1 (en) 2013-04-30
US8569285B2 (en) 2013-10-29
AU2011213898A1 (en) 2012-04-05
ES2421504T3 (es) 2013-09-03
WO2012035216A1 (fr) 2012-03-22
CY1114110T1 (el) 2016-07-27
ZA201106353B (en) 2012-05-30
CA2752131C (fr) 2014-04-22
EA201300340A1 (ru) 2013-08-30
PT2431360E (pt) 2013-05-14
MX2013002892A (es) 2013-04-10
KR20130054438A (ko) 2013-05-24

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ECSP13012489A (es) Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones