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EA201300053A1 - Фосфатсвязывающий препарат для удобного приема - Google Patents

Фосфатсвязывающий препарат для удобного приема

Info

Publication number
EA201300053A1
EA201300053A1 EA201300053A EA201300053A EA201300053A1 EA 201300053 A1 EA201300053 A1 EA 201300053A1 EA 201300053 A EA201300053 A EA 201300053A EA 201300053 A EA201300053 A EA 201300053A EA 201300053 A1 EA201300053 A1 EA 201300053A1
Authority
EA
Eurasian Patent Office
Prior art keywords
containing preparation
phosphate containing
convenient reception
granulate
reception
Prior art date
Application number
EA201300053A
Other languages
English (en)
Inventor
Кай Штротман
Фридрих Шульце
Йоханнес Бартоломэус
Ева Фрис-Шафнер
Астрид Опперман
Original Assignee
Фрезениус Медикел Кэар Дойчланд Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фрезениус Медикел Кэар Дойчланд Гмбх filed Critical Фрезениус Медикел Кэар Дойчланд Гмбх
Publication of EA201300053A1 publication Critical patent/EA201300053A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к фармацевтическому составу в форме сыпучего гранулята или жевательной таблетки, содержащему по меньшей мере одно фосфатсвязывающее вещество и по меньшей мере одно шипучее средство, которое содержит карбонат и твердую, органическую, съедобную кислоту или ее кислую соль, для применения в лечении гиперфосфатемии у пациентов с почечной недостаточностью, причем гранулят вводится орально без добавления воды.
EA201300053A 2010-10-13 2011-10-11 Фосфатсвязывающий препарат для удобного приема EA201300053A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10013578A EP2441436A1 (de) 2010-10-13 2010-10-13 Phosphatbinderformulierung zur einfachen Einnahme
PCT/EP2011/005069 WO2012048846A2 (de) 2010-10-13 2011-10-11 Phosphatbinderformulierung zur einfachen einnahme

Publications (1)

Publication Number Publication Date
EA201300053A1 true EA201300053A1 (ru) 2013-05-30

Family

ID=43567532

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201300053A EA201300053A1 (ru) 2010-10-13 2011-10-11 Фосфатсвязывающий препарат для удобного приема

Country Status (11)

Country Link
US (2) US20130202699A1 (ru)
EP (2) EP2441436A1 (ru)
JP (1) JP6031693B2 (ru)
KR (1) KR101977996B1 (ru)
CN (1) CN103124553A (ru)
AU (1) AU2011316103B2 (ru)
BR (1) BR112013009153B1 (ru)
CA (1) CA2807621C (ru)
EA (1) EA201300053A1 (ru)
ES (1) ES2701443T3 (ru)
WO (1) WO2012048846A2 (ru)

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EP2441436A1 (de) 2010-10-13 2012-04-18 Fresenius Medical Care Deutschland GmbH Phosphatbinderformulierung zur einfachen Einnahme
US20150297490A1 (en) * 2012-11-26 2015-10-22 Apollonia Health Inc. Compositions, uses and methods for treating or preventing dental caries
EP3154512B1 (en) * 2014-05-01 2019-07-24 Hermes Arzneimittel GmbH Solid oral formulations comprising solid melt dispersions of organic acids in xylitol
CN104000791A (zh) * 2014-06-10 2014-08-27 安徽省逸欣铭医药科技有限公司 一种柠檬酸铁咀嚼片
JP6093829B1 (ja) * 2015-10-02 2017-03-08 バイエル薬品株式会社 ランタン化合物を含む医薬組成物
CN107149594B (zh) * 2016-03-02 2021-03-19 北京科信必成医药科技发展有限公司 一种醋酸钙掩味颗粒及其制备方法
JP6217052B2 (ja) * 2016-04-21 2017-10-25 邦赫 小牧 口腔清浄用発泡性錠剤
JP2017193547A (ja) * 2017-05-08 2017-10-26 邦赫 小牧 口腔清浄用発泡性錠剤
US10857092B2 (en) * 2019-03-14 2020-12-08 Glen D Lindbo Avoiding gag reflex to enable swallowing pills
JP2023525279A (ja) * 2020-05-08 2023-06-15 フェルティン ファルマ アー／エス 活性成分の経口送達用フローパック
GR1010127B (el) * 2020-06-30 2021-11-16 Βεννεττ Φαρμακευτικη A.E., Αναβραζοντα κοκκια που περιεχουν αλατα μαγνησιου
CN115024495B (zh) * 2022-06-27 2024-03-22 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用
WO2024039593A1 (en) * 2022-08-15 2024-02-22 Biolink Life Sciences, Inc. Calcium succinate monohydrate formulation
CN116196330B (zh) * 2023-03-16 2024-09-20 广东赛康制药厂有限公司 一种治疗高磷酸血症药物的制备工艺
CN119455019B (zh) * 2024-11-27 2025-10-28 北京华睿鼎信科技有限公司 碳酸镧药用组合物及其应用与治疗高磷血症的药物

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EP2441436A1 (de) 2010-10-13 2012-04-18 Fresenius Medical Care Deutschland GmbH Phosphatbinderformulierung zur einfachen Einnahme

Also Published As

Publication number Publication date
CA2807621A1 (en) 2012-04-19
KR20130117761A (ko) 2013-10-28
US20130202699A1 (en) 2013-08-08
CA2807621C (en) 2018-05-29
US9974805B2 (en) 2018-05-22
CN103124553A (zh) 2013-05-29
BR112013009153B1 (pt) 2021-06-29
WO2012048846A3 (de) 2012-06-07
AU2011316103B2 (en) 2015-06-25
BR112013009153A2 (pt) 2016-07-26
WO2012048846A2 (de) 2012-04-19
ES2701443T3 (es) 2019-02-22
US20160243160A1 (en) 2016-08-25
JP6031693B2 (ja) 2016-11-24
AU2011316103A1 (en) 2013-02-28
KR101977996B1 (ko) 2019-05-13
EP2627313B1 (de) 2018-09-12
JP2013539768A (ja) 2013-10-28
EP2627313A2 (de) 2013-08-21
EP2441436A1 (de) 2012-04-18

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