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EA200800065A1 - Аминокислые соли росиглитазона - Google Patents

Аминокислые соли росиглитазона

Info

Publication number
EA200800065A1
EA200800065A1 EA200800065A EA200800065A EA200800065A1 EA 200800065 A1 EA200800065 A1 EA 200800065A1 EA 200800065 A EA200800065 A EA 200800065A EA 200800065 A EA200800065 A EA 200800065A EA 200800065 A1 EA200800065 A1 EA 200800065A1
Authority
EA
Eurasian Patent Office
Prior art keywords
rosiglitazone
amino acid
acid salts
salts
enantiomeric
Prior art date
Application number
EA200800065A
Other languages
English (en)
Other versions
EA012594B1 (ru
Inventor
Удо Верц
Герхард Мас
Генрих Шталь
Original Assignee
Рациофарм Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рациофарм Гмбх filed Critical Рациофарм Гмбх
Publication of EA200800065A1 publication Critical patent/EA200800065A1/ru
Publication of EA012594B1 publication Critical patent/EA012594B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Noodles (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

В заявке описаны новые аминокислые соли рацемической или энантиомерной либо таутомерной формы росиглитазона (химическое название: 5-(4-[2-(N-метил-N-(2-пиридил)амино)этокси]бензил)-2,4-тиазолидиндион), а также сольваты этих солей.
EA200800065A 2005-07-22 2006-07-20 Аминокислые соли росиглитазона EA012594B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005034406A DE102005034406A1 (de) 2005-07-22 2005-07-22 Neue Salze von Rosiglitazon
PCT/EP2006/007171 WO2007009799A1 (de) 2005-07-22 2006-07-20 Aminosäuresalze von rosiglitazon

Publications (2)

Publication Number Publication Date
EA200800065A1 true EA200800065A1 (ru) 2008-08-29
EA012594B1 EA012594B1 (ru) 2009-10-30

Family

ID=36870547

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800065A EA012594B1 (ru) 2005-07-22 2006-07-20 Аминокислые соли росиглитазона

Country Status (18)

Country Link
US (1) US20080207700A1 (ru)
EP (1) EP1907386B1 (ru)
JP (1) JP2009502760A (ru)
KR (1) KR20080032108A (ru)
CN (1) CN101228157A (ru)
AT (1) ATE469896T1 (ru)
AU (1) AU2006271863A1 (ru)
BR (1) BRPI0613686A2 (ru)
CA (1) CA2616031A1 (ru)
DE (2) DE102005034406A1 (ru)
EA (1) EA012594B1 (ru)
ES (1) ES2344662T3 (ru)
IL (1) IL188661A0 (ru)
NO (1) NO20080704L (ru)
NZ (1) NZ565159A (ru)
UA (1) UA92354C2 (ru)
WO (1) WO2007009799A1 (ru)
ZA (1) ZA200800184B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
EA022924B1 (ru) 2009-04-03 2016-03-31 Ф.Хоффманн-Ля Рош Аг ТВЁРДАЯ ФОРМА {3-[5-(4-ХЛОРФЕНИЛ)-1Н-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ И ЕЁ ПРИМЕНЕНИЕ
TW201041888A (en) * 2009-05-06 2010-12-01 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
MA33975B1 (fr) 2009-11-06 2013-02-01 Plexxikon Inc Composés et méthodes de modulation des kinases et leurs indications d'emploi
JP5941069B2 (ja) 2011-02-07 2016-06-29 プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． キナーゼ調節のための化合物および方法、ならびにそれに対する適応症
US9030870B2 (en) * 2011-08-26 2015-05-12 Micron Technology, Inc. Threshold voltage compensation in a multilevel memory
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US9815777B2 (en) * 2013-09-22 2017-11-14 Jiva Pharma, Inc. Metformin salts to treat Type2 diabetes
CN107789352A (zh) * 2017-10-25 2018-03-13 桂林浩新科技服务有限公司 一种复方药物制剂及在制备治疗高血糖、高血脂的药物中的应用
CN109053717B (zh) * 2018-08-09 2022-05-31 天津理工大学 一种罗格列酮龙胆酸盐及其制备方法
CN109053718B (zh) * 2018-08-09 2022-06-03 天津理工大学 一种罗格列酮糖精盐及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB0014006D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
GB0014005D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
GB0019224D0 (en) * 2000-08-04 2000-09-27 Smithkline Beecham Plc Novel pharmaceutical
GB0021784D0 (en) * 2000-09-05 2000-10-18 Smithkline Beecham Plc Novel pharmaceutical
GB0021865D0 (en) * 2000-09-06 2000-10-18 Smithkline Beecham Plc Novel pharmaceutical
GB0021978D0 (en) * 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
JP2004520326A (ja) * 2000-12-22 2004-07-08 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー ５−［４−［２−（ｎ−メチル−ｎ−（２−ピリジル）アミノ）エトキシ］ベンジル］チアゾリジン−２，４−ジオンメシレート塩
SI1448559T1 (sl) * 2001-11-21 2007-06-30 Smithkline Beecham Plc 5-(4-(2-(n-metil-n-(2-piridil)amino)etoksi)benzil-tiazolidin-2,4-dion- benzensulfonat; postopek za njegovo pripravo; njegovi polimorfi i, ii, iii; in njegova uporaba kot farmacevtska uäśinkovina
AU2002343052A1 (en) * 2001-11-21 2003-06-10 Smithkline Beecham P.L.C. Rosiglitazone edisylates and their use as antidiabetics
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0129872D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0129851D0 (en) * 2001-12-13 2002-01-30 Smithkline Beecham Plc Novel compounds
AU2002350965A1 (en) * 2001-12-13 2003-06-23 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
AU2002352391A1 (en) * 2001-12-13 2003-06-23 Smithkline Beecham Plc A 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione (i) 10-camphorsulphonic acid salt and use against diabetes mellitus
WO2003053962A1 (en) * 2001-12-20 2003-07-03 Smithkline Beecham Plc 5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus
GB0130511D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130509D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130510D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
AU2003269483A1 (en) * 2003-09-10 2005-03-29 Biocon Limited Phosphoric acid salt of 5-((4-(2-(methyl-2-pyridinylamino) ethoxy) phenyl) methyl)- 2,4-thiazolidinedione

Also Published As

Publication number Publication date
BRPI0613686A2 (pt) 2011-01-25
CA2616031A1 (en) 2007-01-25
AU2006271863A1 (en) 2007-01-25
NZ565159A (en) 2010-01-29
DE102005034406A1 (de) 2007-02-01
WO2007009799A1 (de) 2007-01-25
NO20080704L (no) 2008-02-07
EP1907386A1 (de) 2008-04-09
IL188661A0 (en) 2008-08-07
ES2344662T3 (es) 2010-09-02
EP1907386B1 (de) 2010-06-02
UA92354C2 (en) 2010-10-25
CN101228157A (zh) 2008-07-23
ZA200800184B (en) 2009-02-25
EA012594B1 (ru) 2009-10-30
US20080207700A1 (en) 2008-08-28
DE502006007113D1 (de) 2010-07-15
JP2009502760A (ja) 2009-01-29
ATE469896T1 (de) 2010-06-15
KR20080032108A (ko) 2008-04-14

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU