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EA200601568A1 - Новые гидрокси-8-гетероарилфенантридины и их применение в качестве ингибиторов pde4 - Google Patents

Новые гидрокси-8-гетероарилфенантридины и их применение в качестве ингибиторов pde4

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Publication number
EA200601568A1
EA200601568A1 EA200601568A EA200601568A EA200601568A1 EA 200601568 A1 EA200601568 A1 EA 200601568A1 EA 200601568 A EA200601568 A EA 200601568A EA 200601568 A EA200601568 A EA 200601568A EA 200601568 A1 EA200601568 A1 EA 200601568A1
Authority
EA
Eurasian Patent Office
Prior art keywords
application
heteroarryfenanthridines
pde4 inhibitors
new hydroxy
hydroxy
Prior art date
Application number
EA200601568A
Other languages
English (en)
Other versions
EA014155B1 (ru
Inventor
Беате Шмидт
Дитер Флоккерци
Армин Хатцельманн
Кристоф Цитт
Иоганнес Барзиг
Дегенхард Маркс
Ханс-Петер Клей
Ульрих Каутц
Original Assignee
Алтана Фарма Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алтана Фарма Аг filed Critical Алтана Фарма Аг
Publication of EA200601568A1 publication Critical patent/EA200601568A1/ru
Publication of EA014155B1 publication Critical patent/EA014155B1/ru

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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Abstract

В заявке описаны соединения формулы I, в которых R1, R2, R3, R4, R5 и Har имеют значения, указанные в описании заявки, причем указанные соединения являются эффективными ингибиторами PDE4.
EA200601568A 2004-03-03 2005-03-02 Новые гидрокси-8-гетероарилфенантридины и их применение в качестве ингибиторов pde4 EA014155B1 (ru)

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