EA024167B1 - Medication with anti-hemorrhoids action - Google Patents

Abstract

The invention relates to medicine, namely to medications based on Glycyrrhiza glabra, containing material with active ingredients. The task of the disclosed invention is to develop a novel medication for treatment of proctological diseases, which contains thick extract of Glycyrrhiza glabra, in form of suppositories, possessing high therapeutic efficiency for treatment of thromboses of both external and internal hemorrhoids with removal of inflammatory pain anal syndrome. The medication with anti-hemorrhoid action is available in form of ointment or suppositories, made on the basis of propolis, cocoa butter, thick extract of Glycyrrhiza glabra, sea buckthorn oil, thistle oil, iodine tincture, with the tar and Dead Sea salt as the filling agent.

Description

The invention relates to medicine, namely to medicines based on bare licorice containing material with active ingredients.

Currently, hemorrhoid disease has become widespread due to the predominance of physically inactive activity, consumption of high-calorie foods with a low fiber content, violation of diet, etc.

Known means made in the form of candles containing belladonna extract, novocaine, xeroform, cocoa butter (V.P. Ryvkin et al. Hemorrhoids, 1984, M., publishing house Medicine).

Known means for the treatment of hemorrhoids, anal fissures, containing the active substance and filler, in which to increase pharmacological activity use castor oil, beekeeping products, namely bee honey, wax, propolis, bee pollen from flower pollen and pine resin, and in as a filler - butter, 40% ethyl alcohol and water (RF patent No. 2036653, 1995)

A disadvantage of the known agents is that they are capable of causing an allergic reaction and can cause headaches and cramps.

Closest to the claimed tool is an ointment based on propolis (15-20%) and cocoa butter (85-80%) (RF application No. 92004905.1995)

The known agent is also characterized by a possible allergic reaction to propolis and a relatively high cost.

The objective of the invention is the development of a new drug for the treatment of proctological diseases, containing licorice in the form of suppositories, which has high therapeutic efficacy for the treatment of thrombosis of both external and internal hemorrhoids with the removal of inflammatory-pain anal syndrome.

The problem is solved in that the agent has a hemorrhagic effect based on propolis and cocoa butter, where according to the invention additionally contains a thick extract of licorice naked with a moisture content of not more than 25%, an additional fat base - sea buckthorn oil and milk thistle, tincture of iodine and as a filler tar and Dead Sea salt in the following ratio of ingredients, parts by weight:

cocoa butter - 20.0; sea buckthorn oil - 10.0; milk thistle oil - 20.0; propolis - 20.0; tar - 10.0;

salt of the Dead Sea - 2.0; tincture of iodine - 5 drops; thick licorice extract naked - the rest.

The essence of the proposed tool lies in the fact that the new composition based on licorice naked in combination with the claimed ingredients gives a pronounced antihemorrhoid effect and is made in the form of ointment or suppositories.

The components that make up the claimed funds have the following properties.

The thick extract of licorice is a brown liquid with a moisture content of up to 25%, promotes wound healing, has anti-allergic properties. The triterpenes contained in the licorice root affect the water-salt metabolism in the body similarly to the hormones of the adrenal cortex, and also exhibit anti-inflammatory and antimicrobial effects.

Propolis has bactericidal, bacteriostatic, antiviral, fungicidal, antitoxic, and local anesthetic properties.

The main composition of cocoa butter is unsaturated and saturated fatty acids, such as oleic, stearic, lauric, palmitic, linoleic and arachinic acid. It has enveloping, regenerating, analgesic, anti-inflammatory, wound healing properties.

Cocoa butter serves as the basis for the production of ointments, pain relievers.

Tar birch is an antiseptic, has a local irritant, anti-inflammatory, restorative effect, improves blood circulation to tissues.

Dead Sea salt contains chlorine - one of the main regulators of osmotic pressure in the cell, which maintains the necessary water balance; magnesium - increases cell viability and is of great importance as an anti-stress mineral, has anti-allergic effect. Lack of magnesium accelerates the aging process; sodium - supplies energy and, together with chlorine, regulates the moisture level in cells; calcium - strengthens connective tissues, plays a large role in the processes of skin metabolism, wound healing and the prevention of infections; potassium - improves the penetration of nutrients into the cell through cell membranes, regulates the moisture level in the cells; Bromine has antistress and antiseptic properties.

Sea-buckthorn oil helps to get rid of bacteria that have fallen into an open wound, also with its help the wound heals much faster, bleeding stops, pain softens. Sea buckthorn oil is a herbal preparation containing vitamins of groups B, C, E, K, R.

Milk thistle oil is the richest source of carotenoids (precursors of vitamin A), vitamins E, I, K and group B, macro- and microelements (potassium, magnesium, calcium, manganese, iron, zinc, selenium, copper, chromium, which are most useful for the human body). , aluminum, vanadium, boron, etc.) and biologically active substances (flavolignans (silybin, silidianin, silikristin, neohydrocarpine), flavonoids (quartzetine, etc.), chlorophyll, biogenic amines, etc.). A powerful hepatoprotective agent, milk thistle oil has a fairly wide range of properties useful for the human body (immunomodulating, wound healing, bactericidal, anti-inflammatory, analgesic, choleretic, anti-allergic), due to which it has been successfully used for many centuries in the prevention and complex treatment of various diseases (found thistle oil website).

Tincture of iodine is an antiseptic agent.

The tool is prepared as follows.

In a water bath in an enamel bowl (in the claimed ratio of components), cocoa butter is melted, then sea buckthorn oil is added dropwise, then milk thistle oil, with constant stirring and the temperature of the bath is not higher than 50 ° C. Tar, Dead Sea salt and a thick extract of licorice are sequentially introduced into the resulting fat mass. The container with the obtained product is cooled to room temperature and pre-ground propolis is added. Everything is well triturated until a homogeneous mass without lumps is introduced and iodine tincture is introduced.

The tool is made in the form of ointments and candles. The ointment is filled into a tube. The introduction of funds into the anus is carried out using a tip protected from bacteria. You can also apply the ointment in the form of an application to the open wounds of the anus.

The positive effect of this composition is that it can be used in the treatment of prostatitis.

Thus, a remedy based on licorice naked in combination with the claimed ingredients gives a pronounced anti-hemorrhoid effect, eliminating itching and the removal of inflammatory-pain anal syndrome.

Claims (1)

CLAIM A propolis-based anti-hemorrhoid-based agent and cocoa butter, characterized in that the agent additionally contains a thick extract of licorice bare with a moisture content of not more than 25%, sea buckthorn oil, milk thistle oil, tincture of iodine, tar and Dead Sea salt in the following ratio of ingredients, parts by weight: cocoa butter - 20.0; sea buckthorn oil - 10.0; milk thistle oil - 20.0; propolis - 20.0; tar - 10.0; salt of the Dead Sea - 2.0; tincture of iodine - 5 drops; thick licorice extract naked - the rest.