DOP2001000229A - Forma de dosificación de fármaco activada por hidrogel - Google Patents
Forma de dosificación de fármaco activada por hidrogelInfo
- Publication number
- DOP2001000229A DOP2001000229A DO2001000229A DO2001000229A DOP2001000229A DO P2001000229 A DOP2001000229 A DO P2001000229A DO 2001000229 A DO2001000229 A DO 2001000229A DO 2001000229 A DO2001000229 A DO 2001000229A DO P2001000229 A DOP2001000229 A DO P2001000229A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- dosage form
- core
- hydrogel
- drug dosage
- activated drug
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000000017 hydrogel Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una forma de dosificación de liberación controlada comprende núcleo recubierto, comprendiendo el núcleo una composición que contiene fármaco y una composición hinchables de agua y ocupando cada una regiones separadas dentro del núcleo. El recubrimiento que rodea el núcleo es permeable al agua, insoluble en agua y tiene al menos una abertura de suministro. Se describen una diversidad de configuraciones geométricas
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22419900P | 2000-08-09 | 2000-08-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2001000229A true DOP2001000229A (es) | 2002-09-30 |
Family
ID=22839665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2001000229A DOP2001000229A (es) | 2000-08-09 | 2001-08-08 | Forma de dosificación de fármaco activada por hidrogel |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US20030086972A1 (es) |
| EP (1) | EP1326587A2 (es) |
| JP (1) | JP2004505907A (es) |
| KR (1) | KR20030024844A (es) |
| CN (1) | CN1461212A (es) |
| AP (1) | AP2001002237A0 (es) |
| AU (1) | AU2002229141A1 (es) |
| BG (1) | BG107538A (es) |
| BR (1) | BR0113067A (es) |
| CA (1) | CA2418907A1 (es) |
| DO (1) | DOP2001000229A (es) |
| EA (1) | EA200300081A1 (es) |
| EC (1) | ECSP034455A (es) |
| EE (1) | EE200300055A (es) |
| GT (1) | GT200100161A (es) |
| HR (1) | HRP20030082A2 (es) |
| HU (1) | HUP0300722A2 (es) |
| IL (1) | IL154012A0 (es) |
| IS (1) | IS6686A (es) |
| MA (1) | MA26939A1 (es) |
| MX (1) | MXPA03001209A (es) |
| NO (1) | NO20030627L (es) |
| OA (1) | OA12365A (es) |
| PA (1) | PA8524901A1 (es) |
| PE (1) | PE20020307A1 (es) |
| PL (1) | PL360658A1 (es) |
| SV (1) | SV2002000586A (es) |
| TN (1) | TNSN01123A1 (es) |
| UY (1) | UY26876A1 (es) |
| WO (1) | WO2002011702A2 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| NZ518281A (en) * | 1999-12-23 | 2005-01-28 | Pfizer Prod Inc | Controlled release drug dosage core comprising a drug-containing composition and a water-swellable composition |
| AR030557A1 (es) | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| US7964216B2 (en) | 2001-01-12 | 2011-06-21 | Sun Pharma Advanced Research Company Limited | Spaced drug delivery system |
| US20040213848A1 (en) | 2001-09-28 | 2004-10-28 | Shun-Por Li | Modified release dosage forms |
| WO2003096968A2 (en) * | 2002-05-15 | 2003-11-27 | Sun Pharmaceutical Industries Limited | Oral osmotic controlled drug delivery system |
| US8084058B2 (en) | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| KR20100137023A (ko) * | 2002-09-20 | 2010-12-29 | 안드렉스 랩스 엘엘씨 | 약제학적 정제 |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| CA2499955A1 (en) * | 2002-09-28 | 2004-04-08 | Mcneil-Ppc, Inc. | Delayed release dosage forms |
| US7807197B2 (en) | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
| FR2850576B1 (fr) | 2003-02-05 | 2007-03-23 | Ethypharm Sa | Composition comprenant un melange de principes actifs, et procede de preparation |
| WO2004108067A2 (en) * | 2003-04-03 | 2004-12-16 | Sun Pharmaceutical Industries Limited | Programmed drug delivery system |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| AR040157A1 (es) * | 2003-06-06 | 2005-03-16 | Rodriguez Julio Cesar | Una formulacion en microgranulos para administracion oral en suspension acuosa |
| EP1653926A1 (en) * | 2003-08-04 | 2006-05-10 | Pfizer Products Inc. | Dosage forms providing controlled release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors |
| US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
| US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
| WO2006082500A1 (en) * | 2005-02-03 | 2006-08-10 | Pfizer Products Inc. | Dosage forms providing controlled and immediate release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors |
| US20060228413A1 (en) * | 2005-02-28 | 2006-10-12 | Penwest Pharmaceuticals Co. | Controlled release venlafaxine formulations |
| CN101146521A (zh) * | 2005-03-14 | 2008-03-19 | 太阳医药高级研究有限公司 | 提供包含纤维素和甲基丙烯酸衍生物包衣的口服药物输送系统 |
| CA2600736A1 (en) * | 2005-03-16 | 2006-09-21 | Dr. Reddy's Laboratories Ltd. | Delivery system for multiple drugs |
| US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
| CN100448433C (zh) * | 2005-09-21 | 2009-01-07 | 广州贝氏药业有限公司 | 一种克拉霉素肠溶药物组合物 |
| WO2007124372A2 (en) * | 2006-04-20 | 2007-11-01 | Transport Pharmaceuticals, Inc. | Pharmaceutical formulations for iontophoretic methotrexate delivery |
| SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| KR20080076382A (ko) * | 2007-02-15 | 2008-08-20 | (주)아모레퍼시픽 | 실로스타졸의 제어방출 제제 및 그 제조방법 |
| JP2011512349A (ja) * | 2008-02-15 | 2011-04-21 | サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッド | 経口放出制御錠剤 |
| BR112012010895A2 (pt) * | 2009-11-09 | 2019-09-24 | Capsugel Belgium Nv | "fornecimento de veículo". |
| EP2548556B1 (en) | 2010-03-19 | 2016-08-10 | Daiichi Sankyo Company, Limited | Method for improving dissolvability of anticoagulant |
| CN103732227B (zh) * | 2011-08-10 | 2017-04-12 | 第一三共株式会社 | 含有二胺衍生物的药物组合物 |
| EP2950822B1 (en) * | 2013-01-30 | 2019-04-24 | Daewoong Co., Ltd. | Pharmaceutical composition for protecting wounds, providing hemostasis, or preventing adhesion in the gastrointestinal tract |
| MA41868A (fr) * | 2015-04-01 | 2018-02-06 | Spectrum Brands Inc | Pastille retard et procédés s'y rapportant |
| US10350822B1 (en) * | 2018-01-09 | 2019-07-16 | Triastek Inc. | Dosage forms with desired release profiles and methods of designing and making thereof |
| AU2019231699B2 (en) * | 2018-03-07 | 2023-03-09 | Andrew Xian Chen | Aqueous formulations for insoluble drugs |
| AU2022280939A1 (en) * | 2021-05-28 | 2023-10-05 | Amgen Inc. | Formulations of apremilast |
| CN113600179B (zh) * | 2021-09-16 | 2023-07-04 | 山东博霖环保科技发展有限公司 | 一种脱硝催化剂及其制备方法 |
| TW202325285A (zh) * | 2021-10-14 | 2023-07-01 | 靜岡縣公立大學法人 | 粉末製劑 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1025765B (it) * | 1974-11-18 | 1978-08-30 | Gastaldi Francesco | Essiccatore perfezionato a spruzzo |
| US4187617A (en) * | 1978-12-18 | 1980-02-12 | Becker James J Jr | Spray dryer |
| US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
| US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4624848A (en) * | 1984-05-10 | 1986-11-25 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
| US4851232A (en) * | 1987-02-13 | 1989-07-25 | Alza Corporation | Drug delivery system with means for obtaining desirable in vivo release rate pattern |
| GB8820353D0 (en) * | 1988-08-26 | 1988-09-28 | Staniforth J N | Controlled release tablet |
| US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
| US5096716A (en) * | 1988-09-01 | 1992-03-17 | Alza Corporation | Dosage form for administering calcium antagonist nicardipine |
| IL92966A (en) * | 1989-01-12 | 1995-07-31 | Pfizer | Dispensing devices powered by hydrogel |
| US5030452A (en) * | 1989-01-12 | 1991-07-09 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| JPH05178763A (ja) * | 1991-02-19 | 1993-07-20 | Nippon Saafuakutanto Kogyo Kk | 難溶解性薬物溶解剤組成物 |
| EP0758244B2 (en) * | 1994-05-06 | 2008-02-13 | Pfizer Inc. | Controlled-release dosage forms of azithromycin |
| US5654005A (en) * | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
| TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
| WO1999001121A1 (en) * | 1997-07-01 | 1999-01-14 | Pfizer Inc. | Sertraline salts and sustained-release dosage forms of sertraline |
| SK181099A3 (en) * | 1997-07-01 | 2000-07-11 | Pfizer Prod Inc | Solubilized sertraline compositions |
| DE19747261A1 (de) * | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
| US6037346A (en) * | 1997-10-28 | 2000-03-14 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| PL348119A1 (en) * | 1998-10-13 | 2002-05-06 | Pfizer Prod Inc | Sertraline oral concentrate |
| EP1027888B1 (en) * | 1999-02-10 | 2009-06-10 | Pfizer Products Inc. | Osmotic system for delivery of solid amorphous dispersions of drugs |
| US6500459B1 (en) * | 1999-07-21 | 2002-12-31 | Harinderpal Chhabra | Controlled onset and sustained release dosage forms and the preparation thereof |
| AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
| CA2508722A1 (en) * | 2002-12-11 | 2004-06-24 | Pfizer Products Inc. | Controlled-release of an active substance into a high fat environment |
-
2001
- 2001-08-01 US US09/920,056 patent/US20030086972A1/en not_active Abandoned
- 2001-08-03 WO PCT/IB2001/001390 patent/WO2002011702A2/en not_active Ceased
- 2001-08-03 US US10/344,171 patent/US20040052845A1/en not_active Abandoned
- 2001-08-03 HR HR20030082A patent/HRP20030082A2/hr not_active Application Discontinuation
- 2001-08-03 JP JP2002517039A patent/JP2004505907A/ja active Pending
- 2001-08-03 KR KR10-2003-7001861A patent/KR20030024844A/ko not_active Ceased
- 2001-08-03 MX MXPA03001209A patent/MXPA03001209A/es not_active Application Discontinuation
- 2001-08-03 AP APAP/P/2001/002237A patent/AP2001002237A0/en unknown
- 2001-08-03 OA OA1200300043A patent/OA12365A/en unknown
- 2001-08-03 PL PL36065801A patent/PL360658A1/xx not_active Application Discontinuation
- 2001-08-03 EE EEP200300055A patent/EE200300055A/xx unknown
- 2001-08-03 CA CA002418907A patent/CA2418907A1/en not_active Abandoned
- 2001-08-03 IL IL15401201A patent/IL154012A0/xx unknown
- 2001-08-03 HU HU0300722A patent/HUP0300722A2/hu unknown
- 2001-08-03 AU AU2002229141A patent/AU2002229141A1/en not_active Abandoned
- 2001-08-03 CN CN01816024A patent/CN1461212A/zh active Pending
- 2001-08-03 EP EP01984471A patent/EP1326587A2/en not_active Withdrawn
- 2001-08-03 BR BR0113067-6A patent/BR0113067A/pt not_active IP Right Cessation
- 2001-08-03 EA EA200300081A patent/EA200300081A1/ru unknown
- 2001-08-08 SV SV2001000586A patent/SV2002000586A/es not_active Application Discontinuation
- 2001-08-08 UY UY26876A patent/UY26876A1/es not_active Application Discontinuation
- 2001-08-08 PE PE2001000791A patent/PE20020307A1/es not_active Application Discontinuation
- 2001-08-08 DO DO2001000229A patent/DOP2001000229A/es unknown
- 2001-08-08 GT GT200100161A patent/GT200100161A/es unknown
- 2001-08-08 TN TNTNSN01123A patent/TNSN01123A1/fr unknown
- 2001-08-09 PA PA20018524901A patent/PA8524901A1/es unknown
-
2003
- 2003-01-16 IS IS6686A patent/IS6686A/is unknown
- 2003-01-28 EC EC2003004455A patent/ECSP034455A/es unknown
- 2003-01-29 MA MA27017A patent/MA26939A1/fr unknown
- 2003-02-06 BG BG107538A patent/BG107538A/bg unknown
- 2003-02-07 NO NO20030627A patent/NO20030627L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA200300081A1 (ru) | 2003-08-28 |
| SV2002000586A (es) | 2002-10-24 |
| JP2004505907A (ja) | 2004-02-26 |
| MXPA03001209A (es) | 2003-06-30 |
| PL360658A1 (en) | 2004-09-20 |
| EP1326587A2 (en) | 2003-07-16 |
| WO2002011702A2 (en) | 2002-02-14 |
| IL154012A0 (en) | 2003-07-31 |
| IS6686A (is) | 2003-01-16 |
| NO20030627D0 (no) | 2003-02-07 |
| KR20030024844A (ko) | 2003-03-26 |
| WO2002011702A3 (en) | 2002-11-28 |
| HRP20030082A2 (en) | 2003-04-30 |
| US20030086972A1 (en) | 2003-05-08 |
| PE20020307A1 (es) | 2002-04-23 |
| GT200100161A (es) | 2002-03-22 |
| NO20030627L (no) | 2003-04-08 |
| AU2002229141A1 (en) | 2002-02-18 |
| MA26939A1 (fr) | 2004-12-20 |
| US20040052845A1 (en) | 2004-03-18 |
| ECSP034455A (es) | 2003-03-10 |
| CA2418907A1 (en) | 2002-02-14 |
| EE200300055A (et) | 2004-12-15 |
| BG107538A (bg) | 2003-11-28 |
| PA8524901A1 (es) | 2002-04-25 |
| HUP0300722A2 (hu) | 2003-11-28 |
| UY26876A1 (es) | 2002-03-22 |
| OA12365A (en) | 2006-05-16 |
| TNSN01123A1 (fr) | 2005-11-10 |
| BR0113067A (pt) | 2003-07-01 |
| AP2001002237A0 (en) | 2001-09-30 |
| CN1461212A (zh) | 2003-12-10 |
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