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DK92788A - Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retrovira - Google Patents

Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retrovira

Info

Publication number
DK92788A
DK92788A DK092788A DK92788A DK92788A DK 92788 A DK92788 A DK 92788A DK 092788 A DK092788 A DK 092788A DK 92788 A DK92788 A DK 92788A DK 92788 A DK92788 A DK 92788A
Authority
DK
Denmark
Prior art keywords
fluoruanosides
retrovira
deoxy
preparation
medicinal products
Prior art date
Application number
DK092788A
Other languages
English (en)
Other versions
DK172617B1 (da
DK92788D0 (da
Inventor
Bertil Frank Harald Eriksson
Karl Nils Gunnar Johansson
Goeran Bertil Stening
Bo Fredrik Oeberg
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of DK92788A publication Critical patent/DK92788A/da
Publication of DK92788D0 publication Critical patent/DK92788D0/da
Application granted granted Critical
Publication of DK172617B1 publication Critical patent/DK172617B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK198800927A 1986-07-04 1988-02-23 Ny medicinsk anvendelse af nukleosider DK172617B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8602981 1986-07-04
SE8602981A SE8602981D0 (sv) 1986-07-04 1986-07-04 Novel medicinal use
PCT/SE1987/000316 WO1988000050A1 (en) 1986-07-04 1987-07-02 Novel medicinal use of nucleosides
SE8700316 1987-07-02

Publications (3)

Publication Number Publication Date
DK92788A true DK92788A (da) 1988-02-23
DK92788D0 DK92788D0 (da) 1988-02-23
DK172617B1 DK172617B1 (da) 1999-03-01

Family

ID=20365027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198800927A DK172617B1 (da) 1986-07-04 1988-02-23 Ny medicinsk anvendelse af nukleosider

Country Status (10)

Country Link
US (1) US6358934B1 (da)
EP (1) EP0277151B1 (da)
JP (1) JP2540576B2 (da)
AT (1) ATE68349T1 (da)
AU (1) AU598575B2 (da)
CA (1) CA1286991C (da)
DE (1) DE3773892D1 (da)
DK (1) DK172617B1 (da)
SE (1) SE8602981D0 (da)
WO (1) WO1988000050A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
SE9800452D0 (sv) * 1998-02-13 1998-02-13 Medivir Ab Antivirals
GB8719877D0 (en) * 1987-08-22 1987-09-30 Wellcome Found Antiviral compounds
US5506215A (en) * 1987-11-03 1996-04-09 Medivir Ab 1-(3'-fluoro-2',3'-dideoxy-β-D-ribofuranosyl)-5-substituted pyrimidine nucleosides
GB8726136D0 (en) * 1987-11-07 1987-12-09 Wellcome Found Therapeutic nucleosides
SE8802687D0 (sv) * 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier
GB9003543D0 (en) * 1990-02-16 1990-04-11 Wellcome Found Therapeutic nucleosides
GB9200150D0 (en) * 1992-01-06 1992-02-26 Wellcome Found Therapeutic nucleosides
ATE178335T1 (de) * 1992-01-06 1999-04-15 Wellcome Found Therapeutische nukleoside der 2',3'-dideoxy-3'- fluor -purin reihe
US5360714A (en) * 1992-08-28 1994-11-01 Fox Chase Cancer Center Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof
US5334525A (en) * 1992-08-28 1994-08-02 Fox Chase Cancer Center Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof
TW374087B (en) * 1993-05-25 1999-11-11 Univ Yale L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents
US5627160A (en) * 1993-05-25 1997-05-06 Yale University L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
DE69533856T2 (de) * 1994-10-24 2005-12-08 Genencor International, Inc., Palo Alto L-pyranosyl-nukleoside
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
US5869461A (en) * 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
TW580500B (en) * 1997-08-15 2004-03-21 Medivir Ab Nucleoside compounds, and pharmaceutical composition comprising same for use in the prophylaxis or treatment of viral infections
US20060084627A1 (en) * 2002-06-27 2006-04-20 Medivir Ab Synergistic interaction of abacavir and alovudine
WO2004087169A1 (en) * 2003-03-27 2004-10-14 Boehringer Ingelheim International Gmbh Antiviral combination of nevirapine and a further antiretroviral compound
WO2004087140A1 (en) * 2003-03-27 2004-10-14 Boehringer Ingelheim International Gmbh Antiviral combination of a dipyridodiazepinone and a further antiretroviral compound
WO2004087139A1 (en) * 2003-03-27 2004-10-14 Boehringer Ingelheim International Gmbh Antiviral combination of tipranavir and a further antiretroviral compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775397A (en) * 1969-11-12 1973-11-27 Akad Wissenschaften Ddr Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides
DD139793A1 (de) * 1978-11-06 1980-01-23 Waltraud Braun Mittel gegen psoriasis
DD158903A1 (de) * 1981-05-18 1983-02-09 Gotthard Kowollik Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyadenosin
DD209197A1 (de) * 1981-07-21 1984-04-25 Akad Wissenschaften Ddr Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyguanosin
US4724232A (en) 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
CA1314875C (en) * 1985-05-15 1993-03-23 George Walter Koszalka Therapeutic nucleosides
WO1987004929A1 (en) 1986-02-20 1987-08-27 Greer Sheldon B Composition for and method of treating aids and certain related diseases

Also Published As

Publication number Publication date
US6358934B1 (en) 2002-03-19
EP0277151A1 (en) 1988-08-10
DK172617B1 (da) 1999-03-01
DE3773892D1 (de) 1991-11-21
ATE68349T1 (de) 1991-11-15
WO1988000050A1 (en) 1988-01-14
DK92788D0 (da) 1988-02-23
SE8602981D0 (sv) 1986-07-04
EP0277151B1 (en) 1991-10-16
AU598575B2 (en) 1990-06-28
CA1286991C (en) 1991-07-30
JP2540576B2 (ja) 1996-10-02
JPH01500193A (ja) 1989-01-26
AU7700587A (en) 1988-01-29

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired