DK625286A - Indolderivater - Google Patents

Indolderivater

Info

Publication number: DK625286A
Authority: DK; Denmark
Prior art keywords: indole derivatives; indole; derivatives
Prior art date: 1985-12-23

Application number

DK625286A

Other languages

English (en)

Other versions

DK625286D0 (da

Inventor

Dietrich Thielke

Dagmar Hoeltje

Original Assignee

Beecham Wuelfing Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-23

Filing date

1986-12-22

Publication date

1987-06-24

1986-12-22 Application filed by Beecham Wuelfing Gmbh & Co Kg filed Critical Beecham Wuelfing Gmbh & Co Kg

1986-12-22 Publication of DK625286D0 publication Critical patent/DK625286D0/da

1987-06-24 Publication of DK625286A publication Critical patent/DK625286A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK625286A 1985-12-23 1986-12-22 Indolderivater DK625286A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858531612A GB8531612D0 (en)	1985-12-23	1985-12-23	Compounds

Publications (2)

Publication Number	Publication Date
DK625286D0 DK625286D0 (da)	1986-12-22
DK625286A true DK625286A (da)	1987-06-24

Family

ID=10590170

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK625286A DK625286A (da)	1985-12-23	1986-12-22	Indolderivater

Country Status (12)

Country	Link
US (1)	US4980368A (da)
EP (1)	EP0233413B1 (da)
JP (1)	JPS62181252A (da)
AU (1)	AU597017B2 (da)
DE (1)	DE3688397T2 (da)
DK (1)	DK625286A (da)
ES (1)	ES2055688T3 (da)
GB (1)	GB8531612D0 (da)
IE (1)	IE60126B1 (da)
NZ (1)	NZ218754A (da)
PT (1)	PT84014B (da)
ZA (1)	ZA869616B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT97888B (pt) *	1990-06-07	1998-12-31	Zeneca Ltd	Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
US5145845A (en) *	1991-05-14	1992-09-08	Warner-Lambert Co.	Substituted 2-carboxylindoles having pharmaceutical activity
US5233050A (en) *	1992-02-07	1993-08-03	Merck & Co., Inc.	Antimigraine alkyl indole
ITRM20010356A1 (it) *	2001-06-21	2002-12-23	Sigma Tau Ind Farmaceuti	"5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina.
PT2032533E (pt)	2006-06-12	2013-06-28	Novartis Ag	Processo para produzir n-hidroxi-3-[4-[[[2-(2-metil-1hindol- 3-il)etil]amino]metil]fenil]-2e-2-propenamida e materiais de partida para esse fim
WO2014047427A2 (en)	2012-09-21	2014-03-27	Vanderbilt University	Substituted benzofuran, benzothiophene and indole mcl-1 inhibitors
US10005728B2 (en)	2013-08-28	2018-06-26	Vanderbilt University	Substituted indole Mcl-1 inhibitors
AU2015235944B2 (en)	2014-03-27	2020-06-25	Vanderbilt University	Substituted indole Mcl-1 inhibitors
CA3016182C (en)	2016-03-04	2024-02-27	Vanderbilt Universtiy	Substituted indole mcl-1 inhibitors

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA613852A (en) *		1961-01-31	L. Clark Robert	Substituted tryptamines
US3042685A (en) *		1962-07-03		Process of making g-fluoro tryptamine
GB781390A (en) *	1954-04-28	1957-08-21	Upjohn Co	Preparation of 3-(2-aminoethyl)-indoles
GB841524A (en) *	1955-11-18	1960-07-20	May & Baker Ltd	Improvements in or relating to indole derivatives
US2890223A (en) *	1956-03-22	1959-06-09	Research Corp	1-benzyl, 2-methyl, 5-methoxy tryptamine
GB859223A (en) *	1957-03-27	1961-01-18	Merck & Co Inc	Tryptamine compounds
GB888426A (en) *	1957-08-02	1962-01-31	Lab Francais Chimiotherapie	Tryptamine-2-carboxylic acid derivatives and their preparation
US2908691A (en) *	1958-07-14	1959-10-13	Searle & Co	Hydroxyphenalkylaminoalkylindoles and ethers corresponding thereto
US3217029A (en) *	1961-06-27	1965-11-09	Warner Lambert Pharmaceutical	Method of preparing substituted indole derivatives
US3296072A (en) *	1962-06-11	1967-01-03	Upjohn Co	Method of treating mental depression
GB1189064A (en) *	1967-05-01	1970-04-22	Sterling Drug Inc	Indole Derivatives
US3686213A (en) *	1970-08-28	1972-08-22	American Cyanamid Co	Substituted aminoethyl indoles
FR2181559A1 (en) *	1972-04-28	1973-12-07	Aec Chimie Organique Bio	N-Phenylalkyl-N-3-indolylalkyl-alkylamines - with sedative, neuroleptic, analgesic, hypotensive, antiserotonin, adrenolytic activity
GB1374414A (en) *	1972-06-12	1974-11-20	Sterling Drug Inc	1-acyl-3-amino-alkyl-indoles and their preparation
US3915990A (en) *	1973-03-13	1975-10-28	Nelson Res & Dev	Tryptamines
US3910953A (en) *	1973-08-16	1975-10-07	Richter Gedeon Vegyeszet	Process for the preparation of tryptamine or its derivatives

1985
- 1985-12-23 GB GB858531612A patent/GB8531612D0/en active Pending
1986
- 1986-12-22 IE IE337486A patent/IE60126B1/en not_active IP Right Cessation
- 1986-12-22 AU AU66826/86A patent/AU597017B2/en not_active Ceased
- 1986-12-22 DE DE8686310010T patent/DE3688397T2/de not_active Expired - Lifetime
- 1986-12-22 DK DK625286A patent/DK625286A/da not_active Application Discontinuation
- 1986-12-22 ES ES86310010T patent/ES2055688T3/es not_active Expired - Lifetime
- 1986-12-22 EP EP86310010A patent/EP0233413B1/en not_active Expired - Lifetime
- 1986-12-22 ZA ZA869616A patent/ZA869616B/xx unknown
- 1986-12-22 NZ NZ218754A patent/NZ218754A/xx unknown
- 1986-12-23 US US06/946,387 patent/US4980368A/en not_active Expired - Lifetime
- 1986-12-23 JP JP61307566A patent/JPS62181252A/ja active Pending
- 1986-12-23 PT PT84014A patent/PT84014B/pt unknown

Also Published As

Publication number	Publication date
EP0233413A2 (en)	1987-08-26
DE3688397T2 (de)	1993-09-09
US4980368A (en)	1990-12-25
AU597017B2 (en)	1990-05-24
AU6682686A (en)	1987-06-25
PT84014A (en)	1987-01-01
PT84014B (pt)	1989-05-31
JPS62181252A (ja)	1987-08-08
IE60126B1 (en)	1994-06-01
DK625286D0 (da)	1986-12-22
DE3688397D1 (de)	1993-06-09
ZA869616B (en)	1988-09-28
GB8531612D0 (en)	1986-02-05
NZ218754A (en)	1991-05-28
IE863374L (en)	1987-06-23
ES2055688T3 (es)	1994-09-01
EP0233413B1 (en)	1993-05-05
EP0233413A3 (en)	1989-04-26

Publication	Publication Date	Title
DK157686A (da)	1986-10-11	Indolderivater
DK351185A (da)	1986-02-02	Indolderivater
DK133686D0 (da)	1986-03-21	Dipeptidderivater
KR870700064A (ko)	1987-02-28	페닐렌 유도체
DK134687A (da)	1987-09-18	Indolderivater
DK109186D0 (da)	1986-03-10	Dihydropyridazinonderivater
BR8606663A (pt)	1987-08-11	Derivados de triazolil-quinolina
DE3661124D1 (de)	1988-12-15	New phthalide derivatives
DK625286A (da)	1987-06-24	Indolderivater
DK491786A (da)	1987-04-16	Dichloranilinderivater
DK556386A (da)	1987-06-21	Quinilinderivater
DK614887A (da)	1988-05-26	Indolon-derivater
DK303886A (da)	1986-12-29	Secocanthinderivater
GB8620237D0 (en)	1986-10-01	Indole derivatives
DE3662889D1 (de)	1989-05-24	Tetrahydrofurancarboxylic-acid derivatives
KR880700821A (ko)	1988-04-12	데--데옥시테이코플라닌 유도체
KR880701709A (ko)	1988-11-04	히드록시인돌 유도체
GB2184444B (en)	1989-10-18	Indole derivatives
GB2184443B (en)	1989-10-18	Indole derivatives
DK246986A (da)	1986-11-30	Substituerede benzisoindolo-isoquinolinderivater
KR880700791A (ko)	1988-04-12	히드라존 유도체
DK109086A (da)	1986-09-13	2-aminopyrimidinonderivater
DE3662890D1 (de)	1989-05-24	Furobenzisoxazole derivatives
DK259286A (da)	1986-12-05	Azetidinderivater
DK565183D0 (da)	1983-12-08	Indolderivater

Legal Events

Date	Code	Title	Description
1996-03-25	AHS	Application shelved for other reasons than non-payment