DK408186D0 - Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne - Google Patents
Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserneInfo
- Publication number
- DK408186D0 DK408186D0 DK408186A DK408186A DK408186D0 DK 408186 D0 DK408186 D0 DK 408186D0 DK 408186 A DK408186 A DK 408186A DK 408186 A DK408186 A DK 408186A DK 408186 D0 DK408186 D0 DK 408186D0
- Authority
- DK
- Denmark
- Prior art keywords
- podophyllotoxin
- procedures
- derivatives
- compounds
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- YJGVMLPVUAXIQN-UHFFFAOYSA-N epipodophyllotoxin Natural products COC1=C(OC)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YJGVMLPVUAXIQN-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- YJGVMLPVUAXIQN-XVVDYKMHSA-N podophyllotoxin Chemical compound COC1=C(OC)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YJGVMLPVUAXIQN-XVVDYKMHSA-N 0.000 title 1
- 229960001237 podophyllotoxin Drugs 0.000 title 1
- YVCVYCSAAZQOJI-UHFFFAOYSA-N podophyllotoxin Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YVCVYCSAAZQOJI-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Transplantation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8406660 | 1984-12-28 | ||
| SE8406660 | 1984-12-28 | ||
| PCT/SE1985/000541 WO1986004062A1 (en) | 1984-12-28 | 1985-12-20 | Pharmaceutically active compound and a method for its preparation |
| SE8500541 | 1985-12-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK408186D0 true DK408186D0 (da) | 1986-08-27 |
| DK408186A DK408186A (da) | 1986-08-27 |
| DK169506B1 DK169506B1 (da) | 1994-11-14 |
Family
ID=20358339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK408186A DK169506B1 (da) | 1984-12-28 | 1986-08-27 | Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4788216A (da) |
| EP (1) | EP0207124B1 (da) |
| JP (2) | JPH0720966B2 (da) |
| CN (1) | CN1006795B (da) |
| AP (1) | AP32A (da) |
| AT (1) | ATE68186T1 (da) |
| AU (1) | AU585936B2 (da) |
| CA (1) | CA1255230A (da) |
| DE (1) | DE3584370D1 (da) |
| DK (1) | DK169506B1 (da) |
| DZ (1) | DZ876A1 (da) |
| EG (1) | EG17788A (da) |
| ES (1) | ES8701761A1 (da) |
| FI (1) | FI89330C (da) |
| GR (1) | GR853145B (da) |
| HU (1) | HU201672B (da) |
| IL (1) | IL77456A (da) |
| MA (1) | MA20602A1 (da) |
| NO (1) | NO863329D0 (da) |
| PT (1) | PT81760B (da) |
| TN (1) | TNSN86004A1 (da) |
| WO (1) | WO1986004062A1 (da) |
| ZA (1) | ZA859881B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4644072A (en) * | 1985-04-12 | 1987-02-17 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
| ATE186302T1 (de) * | 1989-02-23 | 1999-11-15 | Univ North Carolina | Etoposidanaloge |
| SE464167B (sv) | 1989-07-31 | 1991-03-18 | Analytecon Sa | Topisk farmaceutisk beredning av podophyllotoxin |
| US5332811A (en) * | 1989-09-12 | 1994-07-26 | The University Of North Carolina At Chapel Hill | Etopside analogs |
| US5338867A (en) * | 1992-04-24 | 1994-08-16 | Genelabs Technologies, Inc. | Preparation of 4β- amino podophyllotoxin compounds |
| SE9301831D0 (sv) * | 1993-05-28 | 1993-05-28 | Analytecon S A | Pharmaceutical compositions |
| GB9422947D0 (en) * | 1994-11-14 | 1995-01-04 | Univ Salamanca | Immunosuppressive cyclolignan derivatives |
| US6051721A (en) * | 1997-10-02 | 2000-04-18 | The Board Of Regents Of The University Of Nebraska | Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis |
| FI105152B (fi) | 1998-07-17 | 2000-06-30 | Eero Saarela | Paikallinen kivunlievitysmenetelmä |
| US6143304A (en) * | 1999-08-17 | 2000-11-07 | The University Of Mississippi | Enhanced yield of podophyllotoxin from natural products through in situ conversion methods |
| SE0102168D0 (sv) * | 2001-06-19 | 2001-06-19 | Karolinska Innovations Ab | New use and new compounds |
| DE60233601D1 (de) * | 2001-06-19 | 2009-10-15 | Axelar Ab | Verwendung von bestimmten Cyclolignanen |
| SE0203746D0 (sv) * | 2002-12-18 | 2002-12-18 | Karolinska Innovations Ab | New compounds |
| WO2009157858A1 (en) * | 2008-06-23 | 2009-12-30 | Axelar Ab | Use of cyclolignans for the treatment of a hyperactive immune system |
| WO2013124380A1 (en) * | 2012-02-24 | 2013-08-29 | Nestec S.A. | Peltatin for the treatment of chronic inflammatory disorders |
| WO2015028456A1 (en) * | 2013-08-28 | 2015-03-05 | Nestec S.A. | PPAR modulators |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
| JP7610208B2 (ja) * | 2019-03-22 | 2025-01-08 | インテグレイテッド ナノセラピューティクス インコーポレイテッド | 足場部分から調製した脂質結合体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA635769A (en) * | 1962-01-30 | Rutschmann Jurg | Amides of podophyllic acid and picropodophyllic acid | |
| SE335139B (da) * | 1964-08-12 | 1971-05-17 | Sandoz Ag | |
| US4122092A (en) * | 1977-08-25 | 1978-10-24 | University Of Rochester | Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone |
| US4567253A (en) * | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| GB8424269D0 (en) * | 1984-09-26 | 1984-10-31 | Pharma Medica As | Isolation and purification of podophyllotoxin |
-
1985
- 1985-12-20 HU HU86777D patent/HU201672B/hu not_active IP Right Cessation
- 1985-12-20 AT AT86900345T patent/ATE68186T1/de not_active IP Right Cessation
- 1985-12-20 JP JP61500490A patent/JPH0720966B2/ja not_active Expired - Lifetime
- 1985-12-20 AU AU53003/86A patent/AU585936B2/en not_active Ceased
- 1985-12-20 DE DE8686900345T patent/DE3584370D1/de not_active Expired - Fee Related
- 1985-12-20 WO PCT/SE1985/000541 patent/WO1986004062A1/en not_active Ceased
- 1985-12-20 EP EP86900345A patent/EP0207124B1/en not_active Expired - Lifetime
- 1985-12-20 US US06/908,801 patent/US4788216A/en not_active Expired - Lifetime
- 1985-12-23 AP APAP/P/1985/000017A patent/AP32A/en active
- 1985-12-24 CA CA000498645A patent/CA1255230A/en not_active Expired
- 1985-12-25 EG EG828/85A patent/EG17788A/xx active
- 1985-12-26 PT PT81760A patent/PT81760B/pt not_active IP Right Cessation
- 1985-12-26 IL IL77456A patent/IL77456A/xx unknown
- 1985-12-26 MA MA20828A patent/MA20602A1/fr unknown
- 1985-12-27 ES ES550504A patent/ES8701761A1/es not_active Expired
- 1985-12-27 GR GR853145A patent/GR853145B/el not_active IP Right Cessation
- 1985-12-27 CN CN85109666A patent/CN1006795B/zh not_active Expired
- 1985-12-28 DZ DZ850275A patent/DZ876A1/fr active
- 1985-12-30 ZA ZA859881A patent/ZA859881B/xx unknown
-
1986
- 1986-01-09 TN TNTNSN86004A patent/TNSN86004A1/fr unknown
- 1986-08-19 NO NO1986863329A patent/NO863329D0/no unknown
- 1986-08-27 DK DK408186A patent/DK169506B1/da not_active IP Right Cessation
- 1986-08-27 FI FI863482A patent/FI89330C/fi not_active IP Right Cessation
-
1994
- 1994-10-14 JP JP6274258A patent/JP2572558B2/ja not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |