DK3777842T3 - Melatonin-minitabletter og fremgangsmåde til fremstilling deraf - Google Patents

Melatonin-minitabletter og fremgangsmåde til fremstilling deraf Download PDF

Info

Publication number: DK3777842T3
Authority: DK; Denmark
Prior art keywords: preparation; mini tablets; melatonin mini; melatonin; tablets
Prior art date: 2016-10-31

Application number

DK20195788.3T

Other languages

English (en)

Inventor

Moshe Laudon

Nava Zisapel

Original Assignee

Neurim Pharma 1991

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-10-31

Filing date

2016-11-29

Publication date

2025-02-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57482481&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3777842(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-11-29 Application filed by Neurim Pharma 1991 filed Critical Neurim Pharma 1991

2025-02-03 Application granted granted Critical

2025-02-03 Publication of DK3777842T3 publication Critical patent/DK3777842T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Inorganic Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Anesthesiology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Organic Chemistry (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK20195788.3T 2016-10-31 2016-11-29 Melatonin-minitabletter og fremgangsmåde til fremstilling deraf DK3777842T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201662415014P	2016-10-31	2016-10-31
EP16805903.8A EP3337462B1 (en)	2016-10-31	2016-11-29	Melatonin mini-tablets and method of manufacturing the same

Publications (1)

Publication Number	Publication Date
DK3777842T3 true DK3777842T3 (da)	2025-02-03

Family

ID=57482481

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK20195788.3T DK3777842T3 (da)	2016-10-31	2016-11-29	Melatonin-minitabletter og fremgangsmåde til fremstilling deraf
DK16805903.8T DK3337462T3 (da)	2016-10-31	2016-11-29	Melatonin-minitabletter og fremgangsmåde til fremstilling heraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK16805903.8T DK3337462T3 (da)	2016-10-31	2016-11-29	Melatonin-minitabletter og fremgangsmåde til fremstilling heraf

Country Status (25)

Country	Link
US (2)	US10722494B2 (da)
EP (3)	EP3777842B1 (da)
JP (1)	JP6830156B2 (da)
KR (1)	KR102167190B1 (da)
CN (1)	CN109922795B (da)
AU (6)	AU2016426598C1 (da)
CA (1)	CA3040027C (da)
CY (1)	CY1123449T1 (da)
DK (2)	DK3777842T3 (da)
ES (2)	ES3009413T3 (da)
FI (1)	FI3777842T3 (da)
HR (2)	HRP20201722T1 (da)
HU (2)	HUE051362T2 (da)
IL (1)	IL262537B (da)
LT (2)	LT3777842T (da)
MX (1)	MX386987B (da)
NZ (1)	NZ747702A (da)
PL (2)	PL3337462T3 (da)
PT (2)	PT3337462T (da)
RS (2)	RS66471B1 (da)
SG (1)	SG11201903829PA (da)
SI (2)	SI3777842T1 (da)
SM (2)	SMT202500046T1 (da)
TW (1)	TWI787164B (da)
WO (1)	WO2018078429A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20220125733A1 (en) *	2020-10-23	2022-04-28	Atoz Pharmaceuticals Pvt Ltd	Nongranulated compressed tablets of mesalamine, and process of preparation thereof
KR20230017814A (ko) *	2020-10-26	2023-02-06	일동제약(주)	옥수수불검화추출물을 포함하는 소형화된 경구투여 제제의 제조방법 및 이에 따라 제조된 소형화 제제
CA3268494A1 (en)	2022-10-14	2024-04-18	Nestle Sa	DELAYED-RELEASE MELATONIN COMPOSITIONS

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US4600723A (en)	1983-05-18	1986-07-15	Monash University	Method for minimizing disturbances in circadian rhythms of bodily performance and function
DE122007000073I1 (de)	1991-05-09	2008-01-31	Neurim Pharma 1991	Melatonin enthaltene Arzneimittel
EP0565296B1 (en)	1992-04-07	1996-08-07	Neurim Pharmaceuticals (1991) Limited	Use of melatonin for the manufacture of a medicament for the treatment of benign prostatic hyperplasia
US5449683A (en)	1992-10-01	1995-09-12	Massachussetts Institute Of Technology	Methods of inducing sleep using melatonin
WO1995003043A1 (en) *	1993-07-26	1995-02-02	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University	Sustained release oral compositions containing melatonin
AT408188B (de) *	1995-02-01	2001-09-25	Neurim Pharma 1991	Verwendung von melatonin zur behandlung von an medikamentensucht leidenden patienten
US6469044B1 (en) *	1995-02-01	2002-10-22	Neurim Pharmaceuticals (1991) Ltd.	Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
FR2762513B1 (fr) *	1997-04-23	2003-08-22	Permatec Pharma Ag	Comprimes bioadhesifs
WO2000018374A1 (en)	1998-10-01	2000-04-06	Elan Pharma International, Ltd.	Controlled release nanoparticulate compositions
EP1064938A1 (en) *	1999-06-28	2001-01-03	Sanofi-Synthelabo	Pharmaceutical dosage forms for controlled release producing at least a timed pulse
CN1414851A (zh)	2000-01-05	2003-04-30	纽里姆药品(1991)有限公司	用于治疗对抗高血压药的抗药性和相关病症的方法和制剂
US6458384B2 (en) *	2000-02-23	2002-10-01	Impetus Ag	Pharmaceutical with predetermined activity profile
IL144900A (en)	2001-08-14	2013-12-31	Neurim Pharma 1991	Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en)	2002-04-28	2012-10-31	Neurim Pharma 1991	Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
KR20030016215A (ko) *	2002-07-05	2003-02-26	뉴림 파머슈티칼스 (1991) 리미티드	항고혈압제에 대한 내성 및 관련 질환의 치료를 위한 방법및 제형
AU2004207578B2 (en) *	2003-01-28	2007-06-28	Collegium Pharmaceutical, Inc.	Multiparticulate compositions of milnacipran for oral administration
IL155666A (en)	2003-04-29	2013-12-31	Neurim Pharma 1991	Insomnia treatment
WO2005063297A2 (en)	2003-12-24	2005-07-14	Sepracor Inc.	Melatonin combination therapy for improving sleep quality
FR2889811B1 (fr) *	2005-08-19	2009-10-09	Sanofi Aventis Sa	Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.
DE102006006532B4 (de)	2006-02-10	2007-11-08	Biogenerics Pharma Gmbh	Pharmazeutische Zubereitung
CN101754753A (zh)	2007-05-24	2010-06-23	纽约市哥伦比亚大学托管会	褪黑素的持久释放配方
US20100159001A1 (en) *	2008-12-19	2010-06-24	Cardinal John R	Extended-Release Pharmaceutical Formulations
WO2012103411A2 (en)	2011-01-28	2012-08-02	Zx Pharma, Llc	Controlled-release melatonin composition and related methods
US9532952B2 (en)	2011-01-28	2017-01-03	Physician's Seal, LLC	Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
RU2488388C1 (ru) *	2012-05-24	2013-07-27	Ооо "Валента Интеллект"	Фармацевтическая композиция для профилактики и лечения психических, поведенческих, когнитивных расстройств
ES2677247T3 (es)	2014-05-28	2018-07-31	Valpharma S.P.A.	Formulación para administración oral que comprende melatonina en forma estable y método de producción de la misma

2016
- 2016-11-29 EP EP20195788.3A patent/EP3777842B1/en active Active
- 2016-11-29 HU HUE16805903A patent/HUE051362T2/hu unknown
- 2016-11-29 CA CA3040027A patent/CA3040027C/en active Active
- 2016-11-29 PL PL16805903T patent/PL3337462T3/pl unknown
- 2016-11-29 KR KR1020187035251A patent/KR102167190B1/ko active Active
- 2016-11-29 CN CN201680090550.4A patent/CN109922795B/zh active Active
- 2016-11-29 ES ES20195788T patent/ES3009413T3/es active Active
- 2016-11-29 SI SI201631888T patent/SI3777842T1/sl unknown
- 2016-11-29 DK DK20195788.3T patent/DK3777842T3/da active
- 2016-11-29 SM SM20250046T patent/SMT202500046T1/it unknown
- 2016-11-29 MX MX2019004736A patent/MX386987B/es unknown
- 2016-11-29 JP JP2019519420A patent/JP6830156B2/ja active Active
- 2016-11-29 WO PCT/IB2016/057190 patent/WO2018078429A1/en not_active Ceased
- 2016-11-29 HR HRP20201722TT patent/HRP20201722T1/hr unknown
- 2016-11-29 HU HUE20195788A patent/HUE070190T2/hu unknown
- 2016-11-29 LT LTEP20195788.3T patent/LT3777842T/lt unknown
- 2016-11-29 FI FIEP20195788.3T patent/FI3777842T3/fi not_active Application Discontinuation
- 2016-11-29 PT PT168059038T patent/PT3337462T/pt unknown
- 2016-11-29 PL PL20195788.3T patent/PL3777842T3/pl unknown
- 2016-11-29 ES ES16805903T patent/ES2828034T3/es active Active
- 2016-11-29 NZ NZ747702A patent/NZ747702A/en active IP Right Revival
- 2016-11-29 LT LTEP16805903.8T patent/LT3337462T/lt unknown
- 2016-11-29 EP EP16805903.8A patent/EP3337462B1/en active Active
- 2016-11-29 SG SG11201903829PA patent/SG11201903829PA/en unknown
- 2016-11-29 HR HRP20250166TT patent/HRP20250166T1/hr unknown
- 2016-11-29 AU AU2016426598A patent/AU2016426598C1/en active Active
- 2016-11-29 RS RS20250094A patent/RS66471B1/sr unknown
- 2016-11-29 SI SI201630947T patent/SI3337462T1/sl unknown
- 2016-11-29 SM SM20200575T patent/SMT202000575T1/it unknown
- 2016-11-29 DK DK16805903.8T patent/DK3337462T3/da active
- 2016-11-29 RS RS20201242A patent/RS61024B1/sr unknown
- 2016-11-29 EP EP24208766.6A patent/EP4474012A3/en active Pending
- 2016-11-29 PT PT201957883T patent/PT3777842T/pt unknown
- 2016-12-26 TW TW105143159A patent/TWI787164B/zh active
2018
- 2018-10-24 IL IL262537A patent/IL262537B/en active IP Right Grant
- 2018-10-31 US US16/176,338 patent/US10722494B2/en active Active
2019
- 2019-01-24 AU AU2019200479A patent/AU2019200479B2/en active Active
- 2019-11-28 AU AU2019101470A patent/AU2019101470B4/en not_active Expired
2020
- 2020-06-16 US US16/902,419 patent/US10869857B2/en active Active
- 2020-10-14 CY CY20201100971T patent/CY1123449T1/el unknown
2021
- 2021-01-18 AU AU2021200268A patent/AU2021200268A1/en not_active Abandoned
2023
- 2023-03-31 AU AU2023202003A patent/AU2023202003A1/en active Pending
2025
- 2025-09-18 AU AU2025234204A patent/AU2025234204A1/en active Pending

Also Published As

Publication number	Publication date
AU2016426598A1 (en)	2018-05-17
TW201817418A (zh)	2018-05-16
KR102167190B1 (ko)	2020-10-19
AU2016426598B2 (en)	2018-11-01
EP4474012A2 (en)	2024-12-11
SMT202000575T1 (it)	2021-01-05
AU2023202003A1 (en)	2023-05-04
NZ747702A (en)	2022-08-26
AU2021200268A1 (en)	2021-03-18
LT3337462T (lt)	2021-01-11
FI3777842T3 (fi)	2025-02-11
CA3040027A1 (en)	2018-05-03
AU2016426598C1 (en)	2024-02-08
CA3040027C (en)	2023-08-15
WO2018078429A1 (en)	2018-05-03
MX2019004736A (es)	2019-06-17
CN109922795A (zh)	2019-06-21
ES3009413T3 (en)	2025-03-26
HUE070190T2 (hu)	2025-05-28
JP6830156B2 (ja)	2021-02-17
RS66471B1 (sr)	2025-03-31
LT3777842T (lt)	2025-04-10
HUE051362T2 (hu)	2021-03-01
IL262537A (en)	2018-12-31
EP3337462A1 (en)	2018-06-27
RS61024B1 (sr)	2020-12-31
SI3337462T1 (sl)	2021-01-29
US10869857B2 (en)	2020-12-22
US20190060277A1 (en)	2019-02-28
US20200306227A1 (en)	2020-10-01
AU2019200479B2 (en)	2020-10-22
HRP20250166T1 (hr)	2025-05-09
EP4474012A3 (en)	2025-03-12
SMT202500046T1 (it)	2025-03-12
CN109922795B (zh)	2021-10-08
JP2019533672A (ja)	2019-11-21
SI3777842T1 (sl)	2025-03-31
TWI787164B (zh)	2022-12-21
US10722494B2 (en)	2020-07-28
MX386987B (es)	2025-03-19
PL3337462T3 (pl)	2021-01-25
PT3777842T (pt)	2025-02-11
IL262537B (en)	2021-03-25
NZ782840A (en)	2025-02-28
AU2025234204A1 (en)	2025-10-09
CY1123449T1 (el)	2022-03-24
EP3337462B1 (en)	2020-09-30
AU2019101470A4 (en)	2020-01-16
EP3777842A1 (en)	2021-02-17
AU2019200479A1 (en)	2019-02-14
PL3777842T3 (pl)	2025-05-12
AU2019101470B4 (en)	2020-06-25
HRP20201722T1 (hr)	2021-03-05
EP3777842B1 (en)	2024-12-11
PT3337462T (pt)	2020-10-30
DK3337462T3 (da)	2020-10-12
SG11201903829PA (en)	2019-05-30
ES2828034T3 (es)	2021-05-25
KR20190014512A (ko)	2019-02-12

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