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DK3746568T5 - Crispr-effektorsystembaseret diagnostik - Google Patents

Crispr-effektorsystembaseret diagnostik Download PDF

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Publication number
DK3746568T5
DK3746568T5 DK19705046.1T DK19705046T DK3746568T5 DK 3746568 T5 DK3746568 T5 DK 3746568T5 DK 19705046 T DK19705046 T DK 19705046T DK 3746568 T5 DK3746568 T5 DK 3746568T5
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Prior art keywords
system based
crispr effector
effector system
based diagnostics
diagnostics
Prior art date
Application number
DK19705046.1T
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English (en)
Other versions
DK3746568T3 (da
Inventor
Feng Zhang
Jonathan Gootenberg
Omar Abudayyeh
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Broad Inst Inc
Massachusetts Inst Technology
Harvard College
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Publication of DK3746568T3 publication Critical patent/DK3746568T3/da
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Publication of DK3746568T5 publication Critical patent/DK3746568T5/da

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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
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DK19705046.1T 2018-01-29 2019-01-29 Crispr-effektorsystembaseret diagnostik DK3746568T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862623531P 2018-01-29 2018-01-29
PCT/US2019/015726 WO2019148206A1 (en) 2018-01-29 2019-01-29 Crispr effector system based diagnostics

Publications (2)

Publication Number Publication Date
DK3746568T3 DK3746568T3 (da) 2023-12-18
DK3746568T5 true DK3746568T5 (da) 2024-08-26

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DK19705046.1T DK3746568T5 (da) 2018-01-29 2019-01-29 Crispr-effektorsystembaseret diagnostik

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Country Link
US (1) US20210371926A1 (da)
EP (1) EP3746568B1 (da)
JP (2) JP7527961B2 (da)
KR (1) KR102857066B1 (da)
CN (1) CN112020562B (da)
AU (1) AU2019213047B2 (da)
BR (1) BR112020015093A2 (da)
CA (1) CA3087362A1 (da)
DK (1) DK3746568T5 (da)
FI (1) FI3746568T3 (da)
IL (1) IL276349A (da)
RU (1) RU2020128413A (da)
WO (1) WO2019148206A1 (da)

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CA3022928A1 (en) 2016-05-05 2017-11-09 Massachusetts Institute Of Technology Methods and uses for remotely triggered protease activity measurements
AU2018248327B2 (en) 2017-04-07 2024-10-10 Massachusetts Institute Of Technology Methods to spatially profile protease activity in tissue and sections
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US12173349B2 (en) 2018-09-25 2024-12-24 Massachusetts Institute Of Technology Lung protease nanosensors and uses thereof
WO2020142754A2 (en) 2019-01-04 2020-07-09 Mammoth Biosciences, Inc. Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection
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US11591634B1 (en) * 2019-04-03 2023-02-28 The Trustees Of Boston College Forecasting bacterial survival-success and adaptive evolution through multiomics stress-response mapping and machine learning
KR102452590B1 (ko) * 2019-08-01 2022-10-12 기초과학연구원 CRISPR/Cas9 매개 체세포 핵 이식에 의한 개 디스트로핀병증 모델 생성 및 이의 용도
CN110548134A (zh) * 2019-09-10 2019-12-10 中国医学科学院病原生物学研究所 Cas13a在拮抗病毒中的应用
CN110894557A (zh) * 2019-09-20 2020-03-20 武汉大学 基于CRISPR方式检测非洲猪瘟病毒的crRNA及试剂盒
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WO2021146641A1 (en) 2020-01-17 2021-07-22 The Broad Institute, Inc. Small type ii-d cas proteins and methods of use thereof
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EP3875602A1 (en) 2020-03-05 2021-09-08 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO Nucleic acid fluorescence detection
CN111575299A (zh) * 2020-05-11 2020-08-25 吉林农业大学 牛荚膜a型多杀性巴氏杆菌免疫磁珠的制备方法
WO2022059555A1 (ja) * 2020-09-15 2022-03-24 東洋紡株式会社 改良されたマルチプレックスｐｃｒによる検査方法
WO2022080343A1 (ja) * 2020-10-13 2022-04-21 キヤノン株式会社 核酸検出装置および核酸の検出方法
CN112195164B (zh) * 2020-12-07 2021-04-23 中国科学院动物研究所 工程化的Cas效应蛋白及其使用方法
CN112782138B (zh) * 2020-12-24 2021-10-29 生物岛实验室 用于检测细胞外囊泡的试剂盒及其应用
CN112831544B (zh) * 2020-12-31 2024-06-14 华南农业大学 一种基于CRISPR/Cas12a系统的生物检测方法和生物检测装置
CN113234795B (zh) * 2021-04-15 2023-02-24 山东舜丰生物科技有限公司 利用Cas蛋白进行核酸检测的方法
CN113186253B (zh) * 2021-04-27 2022-06-21 福州大学 一种用于检测路易体病标志物的Cas12a-DNAzyme传感器及其制备方法
CN113373170A (zh) * 2021-04-29 2021-09-10 江西农业大学 一种pFnCpfAb/pCrAb双质粒系统及其应用
CN113373264B (zh) * 2021-06-10 2022-04-12 安徽医科大学 一种基于CRISPR/Cas系统的新型冠状病毒双靶标快速检测方法及试剂盒
EP4367239A4 (en) 2021-07-08 2025-07-23 Univ Montana State CRISPR-BASED PROGRAMMABLE RNA EDITING
CN113552103B (zh) * 2021-07-20 2022-12-30 济南大学 一种基于CRISPR-Cas系统的检测外泌体的荧光生物传感器
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