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DK3589298T3 - Mesenkymale stamceller udvundet af wharton-gelé til behandling af sepsis - Google Patents

Mesenkymale stamceller udvundet af wharton-gelé til behandling af sepsis Download PDF

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Publication number
DK3589298T3
DK3589298T3 DK18712945.7T DK18712945T DK3589298T3 DK 3589298 T3 DK3589298 T3 DK 3589298T3 DK 18712945 T DK18712945 T DK 18712945T DK 3589298 T3 DK3589298 T3 DK 3589298T3
Authority
DK
Denmark
Prior art keywords
wharton
sepsis
jelly
treatment
stem cells
Prior art date
Application number
DK18712945.7T
Other languages
English (en)
Inventor
Danièle Bensoussan
Sébastien Gibot
Caroline Laroye
Amir Boufenzer
Céline Huselstein
Léonore Avercenc
Loïc Reppel
Original Assignee
Univ De Lorraine
Centre Hospitalier Regional Univ De Nancy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ De Lorraine, Centre Hospitalier Regional Univ De Nancy filed Critical Univ De Lorraine
Application granted granted Critical
Publication of DK3589298T3 publication Critical patent/DK3589298T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0668Mesenchymal stem cells from other natural sources

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK18712945.7T 2017-02-28 2018-02-28 Mesenkymale stamceller udvundet af wharton-gelé til behandling af sepsis DK3589298T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1751649 2017-02-28
PCT/FR2018/050472 WO2018158542A1 (fr) 2017-02-28 2018-02-28 Cellules souches mesenchymateuses issues de la gelée de wharton pur le traitement du sepsis

Publications (1)

Publication Number Publication Date
DK3589298T3 true DK3589298T3 (da) 2022-09-26

Family

ID=59070788

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18712945.7T DK3589298T3 (da) 2017-02-28 2018-02-28 Mesenkymale stamceller udvundet af wharton-gelé til behandling af sepsis

Country Status (11)

Country Link
US (2) US11963984B2 (da)
EP (2) EP3589298B1 (da)
JP (2) JP7248984B2 (da)
CN (1) CN110520138A (da)
AU (1) AU2018228352B2 (da)
CA (1) CA3054588A1 (da)
DK (1) DK3589298T3 (da)
ES (1) ES2927203T3 (da)
PL (1) PL3589298T3 (da)
PT (1) PT3589298T (da)
WO (1) WO2018158542A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3177567A1 (en) * 2020-03-31 2021-10-07 Cell Exosome Therapeutics Inc. Method of producing proliferated cells, method of producing cell product, mesenchymal stem cell population and method of producing same, culture supernatant of stem cells and method of producing same, and therapeutic agent
FR3131860B1 (fr) 2022-01-14 2024-05-17 Steminov Dispositif pour la manipulation et le traitement d’objets biologiques et procédé d’utilisation
CN115089611A (zh) * 2022-06-28 2022-09-23 北京三有利康细胞科技有限公司 一种cd146+或cd146-脐带间充质干细胞亚群在制备防治脓毒症的产品中的应用
CN116083353B (zh) * 2022-12-02 2025-10-17 唐颐生物医学(天津)有限公司 一种过表达Anxa1的脐带间充质干细胞外泌体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0814249D0 (en) 2008-08-04 2008-09-10 Cellerix Sa Uses of mesenchymal stem cells
WO2011101834A1 (en) * 2010-02-22 2011-08-25 Advanced Neuro-Science Allies Private Limited A method for obtaining mesenchymal stem cells, media, methods and composition thereof
ES2634545T3 (es) * 2010-06-01 2017-09-28 Auxocell Laboratories, Inc. Células madre nativas de la gelatina de Wharton y su purificación
CN109432126B (zh) * 2011-03-11 2022-06-14 儿童医学中心公司 与间充质干细胞外来体相关的方法和组合物
WO2014200068A1 (ja) * 2013-06-12 2014-12-18 株式会社資生堂 間葉系幹細胞の低酸素培養法
CN103352026B (zh) * 2013-07-24 2016-08-10 黑龙江天晴干细胞股份有限公司 人脐带血富血小板裂解液培养自体脐带间充质干细胞方法
PH12015000014A1 (en) * 2014-06-24 2016-10-17 Stempeutics Res Pvt Ltd Methods of upscaling mesenchymal stromal cell production, compositions and kit thereof
SG11201610844PA (en) 2014-06-30 2017-01-27 Tigenix S A U Mesenchymal stromal cells for treating sepsis
CN104666347B (zh) * 2015-02-28 2019-08-09 广州医科大学附属第一医院 脐带间充质干细胞在制备治疗肺间质纤维化的药物制剂中的应用
RU2604672C1 (ru) * 2015-06-05 2016-12-10 Федеральное государственное бюджетное учреждение "Гематологический научный центр" Министерства Здравоохранения Российской Федерации (ФГБУ "ГНЦ" МЗ РФ) Способ лечения септического шока в состоянии агранулоцитоза
US20170296588A1 (en) * 2016-04-19 2017-10-19 AngioStem, Inc. Mesenchymal stem cells derived from placental sources
CN105861430B (zh) * 2016-04-29 2019-07-23 南京大学 一种外泌体、外泌体的制备方法及其在制备治疗脓毒症药物或者制剂中的应用

Also Published As

Publication number Publication date
US20240245732A1 (en) 2024-07-25
PL3589298T3 (pl) 2022-10-24
JP7248984B2 (ja) 2023-03-30
JP2023060299A (ja) 2023-04-27
CN110520138A (zh) 2019-11-29
WO2018158542A1 (fr) 2018-09-07
CA3054588A1 (en) 2018-09-07
US20200000856A1 (en) 2020-01-02
US11963984B2 (en) 2024-04-23
ES2927203T3 (es) 2022-11-03
AU2018228352B2 (en) 2024-08-01
EP3589298A1 (fr) 2020-01-08
JP2020508679A (ja) 2020-03-26
EP3589298B1 (fr) 2022-06-22
WO2018158542A8 (fr) 2018-10-11
AU2018228352A1 (en) 2019-09-26
PT3589298T (pt) 2022-09-22
EP4091618A1 (fr) 2022-11-23

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