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DK3583126T3 - Multispecifikke bindingsmolekyler med specificitet for dystroglycan og laminin-2 - Google Patents

Multispecifikke bindingsmolekyler med specificitet for dystroglycan og laminin-2

Info

Publication number
DK3583126T3
DK3583126T3 DK18711427.7T DK18711427T DK3583126T3 DK 3583126 T3 DK3583126 T3 DK 3583126T3 DK 18711427 T DK18711427 T DK 18711427T DK 3583126 T3 DK3583126 T3 DK 3583126T3
Authority
DK
Denmark
Prior art keywords
dystroglycan
laminin
specificity
binding molecules
multispecific binding
Prior art date
Application number
DK18711427.7T
Other languages
English (en)
Inventor
Leila Sevigny
Christian Beil
William H Brondyk
Yangde Chen
Seng H Cheng
Timothy D Connors
Catherine Devaud
Dietmar Hoffmann
Maureen Magnay
Tristan Magnay
Catherine Prades
Ercole Rao
Ronnie Wei
Hongmei Zhao
Yunxiang Zhu
Christian Lange
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Priority claimed from PCT/US2018/000056 external-priority patent/WO2018151841A1/en
Application granted granted Critical
Publication of DK3583126T3 publication Critical patent/DK3583126T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK18711427.7T 2017-02-17 2018-02-16 Multispecifikke bindingsmolekyler med specificitet for dystroglycan og laminin-2 DK3583126T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762460663P 2017-02-17 2017-02-17
PCT/US2018/000056 WO2018151841A1 (en) 2017-02-17 2018-02-16 Multispecific binding molecules having specificity to dystroglycan and laminin-2

Publications (1)

Publication Number Publication Date
DK3583126T3 true DK3583126T3 (da) 2025-11-17

Family

ID=66669231

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18711427.7T DK3583126T3 (da) 2017-02-17 2018-02-16 Multispecifikke bindingsmolekyler med specificitet for dystroglycan og laminin-2

Country Status (4)

Country Link
EP (2) EP4659808A2 (da)
CN (2) CN110997714B (da)
AR (1) AR110985A1 (da)
DK (1) DK3583126T3 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201832778A (zh) * 2016-11-10 2018-09-16 美商麥迪紐有限責任公司 對ａｓｃｔ２具有特異性的結合分子及其用途
CN112843234B (zh) * 2021-01-20 2022-09-06 四川大学华西第二医院 一种调控生物机体内gdp-甘露糖的浓度的装置
CN115873127A (zh) * 2021-11-26 2023-03-31 深圳科兴药业有限公司 重组长效人生长激素融合蛋白及其制备方法和用途
CN114736944A (zh) * 2022-04-14 2022-07-12 山东大学深圳研究院 一种化学酶法合成α-肌营养不良蛋白聚糖相关糖肽的方法
CN118990500B (zh) * 2024-09-14 2025-11-04 东华大学 一种基于生成对抗学习的机器人七自由度抓取方法
CN119648494B (zh) * 2024-12-11 2025-06-24 恒大培冠教育科技有限公司 线上教育系统的学前儿童个性化学习路径规划方法及系统

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
JP2826272B2 (ja) 1993-10-26 1998-11-18 タイガースポリマー株式会社 中空樹脂成形品の製造装置及び製造方法
JP4115517B2 (ja) * 1994-01-25 2008-07-09 エラン ファーマシューティカルズ， インコーポレイテッド 白血球付着分子 ｖｌａ−４に対するヒト化抗体
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
BR9606706A (pt) 1995-10-16 1999-04-06 Unilever Nv Análogo de fragmento de anticorpo biespecífico ou bivalente uso processo para produzir o mesmo
CA2377427A1 (en) * 1999-06-28 2001-01-04 National Research Council Of Canada Glycosyltransferases of helicobacter pylori as a new target in prevention and teatment of h. pylori infections
PT1355919E (pt) 2000-12-12 2011-03-02 Medimmune Llc Moléculas com semivida longa, composições que as contêm e suas utilizações
US7078379B2 (en) * 2002-06-03 2006-07-18 Santhera Pharmaceuticals (Schweiz) Gmbh Treatment of congenital muscular dystrophies
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
MX368932B (es) 2009-06-26 2019-10-22 Regeneron Pharma Anticuerpos biespecificos facilmente aislados con formato de inmunoglobulina original.
CN110066339A (zh) 2010-04-20 2019-07-30 根马布股份公司 含异二聚体抗体fc的蛋白及其制备方法
TWI803876B (zh) 2011-03-28 2023-06-01 法商賽諾菲公司 具有交叉結合區定向之雙重可變區類抗體結合蛋白
US9790268B2 (en) 2012-09-12 2017-10-17 Genzyme Corporation Fc containing polypeptides with altered glycosylation and reduced effector function
BR112018070998A2 (pt) 2016-04-13 2019-02-26 Sanofi proteínas de ligação triespecíficas e/ou trivalentes

Also Published As

Publication number Publication date
AR110985A1 (es) 2019-05-22
EP4659808A2 (en) 2025-12-10
EP3583126A1 (en) 2019-12-25
EP3583126B1 (en) 2025-08-27
CN110997714A (zh) 2020-04-10
CN118955707A (zh) 2024-11-15
CN110997714B (zh) 2024-05-03

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