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DK3169704T3 - Molekyler med specificitet for cd45 og cd79 - Google Patents

Molekyler med specificitet for cd45 og cd79 Download PDF

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Publication number
DK3169704T3
DK3169704T3 DK15738655.8T DK15738655T DK3169704T3 DK 3169704 T3 DK3169704 T3 DK 3169704T3 DK 15738655 T DK15738655 T DK 15738655T DK 3169704 T3 DK3169704 T3 DK 3169704T3
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DK
Denmark
Prior art keywords
molecules
Prior art date
Application number
DK15738655.8T
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English (en)
Inventor
Helene Margaret Finney
Stephen Edward Rapecki
Michael John Wright
Kerry Tyson
Original Assignee
UCB Biopharma SRL
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Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
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Publication of DK3169704T3 publication Critical patent/DK3169704T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/289Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK15738655.8T 2014-07-16 2015-07-16 Molekyler med specificitet for cd45 og cd79 DK3169704T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1412659.3A GB201412659D0 (en) 2014-07-16 2014-07-16 Molecules
PCT/EP2015/066368 WO2016009029A1 (en) 2014-07-16 2015-07-16 Molecules with specificity for cd45 and cd79

Publications (1)

Publication Number Publication Date
DK3169704T3 true DK3169704T3 (da) 2020-10-26

Family

ID=51454240

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15738655.8T DK3169704T3 (da) 2014-07-16 2015-07-16 Molekyler med specificitet for cd45 og cd79

Country Status (25)

Country Link
US (2) US10774152B2 (da)
EP (1) EP3169704B1 (da)
JP (1) JP2017529061A (da)
KR (1) KR20170035930A (da)
CN (1) CN106661112A (da)
AU (1) AU2015289093A1 (da)
BR (1) BR112016030908A2 (da)
CA (1) CA2953275A1 (da)
CL (1) CL2017000111A1 (da)
CO (1) CO2017000300A2 (da)
CY (1) CY1123441T1 (da)
DK (1) DK3169704T3 (da)
ES (1) ES2823950T3 (da)
GB (1) GB201412659D0 (da)
HR (1) HRP20201503T1 (da)
HU (1) HUE052282T2 (da)
IL (1) IL249536A0 (da)
LT (1) LT3169704T (da)
MX (1) MX2016017271A (da)
PL (1) PL3169704T3 (da)
PT (1) PT3169704T (da)
RU (1) RU2747980C2 (da)
SG (1) SG11201610565XA (da)
SI (1) SI3169704T1 (da)
WO (1) WO2016009029A1 (da)

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AU2015289093A1 (en) 2017-02-02
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US10774152B2 (en) 2020-09-15
CY1123441T1 (el) 2021-12-31
RU2747980C2 (ru) 2021-05-18
CN106661112A (zh) 2017-05-10
PT3169704T (pt) 2020-11-03
KR20170035930A (ko) 2017-03-31
BR112016030908A2 (pt) 2018-01-16
JP2017529061A (ja) 2017-10-05
RU2017104813A (ru) 2018-08-17
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US20170204183A1 (en) 2017-07-20
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SI3169704T1 (sl) 2020-11-30
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IL249536A0 (en) 2017-02-28
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US20190359713A1 (en) 2019-11-28

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