DK3570819T3 - Medicinsk behandling omfattende enteral indgivelse af edaravone - Google Patents
Medicinsk behandling omfattende enteral indgivelse af edaravone Download PDFInfo
- Publication number
- DK3570819T3 DK3570819T3 DK17737775.1T DK17737775T DK3570819T3 DK 3570819 T3 DK3570819 T3 DK 3570819T3 DK 17737775 T DK17737775 T DK 17737775T DK 3570819 T3 DK3570819 T3 DK 3570819T3
- Authority
- DK
- Denmark
- Prior art keywords
- edaravone
- medical treatment
- enteral administration
- enteral
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17151741 | 2017-01-17 | ||
| PCT/EP2017/067005 WO2018133957A1 (en) | 2017-01-17 | 2017-07-06 | Medical treatment comprising enteral administration of edaravone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3570819T3 true DK3570819T3 (da) | 2021-04-06 |
Family
ID=57850912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17737775.1T DK3570819T3 (da) | 2017-01-17 | 2017-07-06 | Medicinsk behandling omfattende enteral indgivelse af edaravone |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10966960B2 (da) |
| EP (1) | EP3570819B1 (da) |
| JP (1) | JP6898027B2 (da) |
| AU (1) | AU2017394478B2 (da) |
| BR (1) | BR112019014712A2 (da) |
| CA (1) | CA3050031A1 (da) |
| DK (1) | DK3570819T3 (da) |
| ES (1) | ES2868955T3 (da) |
| MX (1) | MX390101B (da) |
| PL (1) | PL3570819T3 (da) |
| PT (1) | PT3570819T (da) |
| WO (1) | WO2018133957A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017394478B2 (en) | 2017-01-17 | 2023-07-20 | Treeway Tw001 B.V. | Medical treatment comprising enteral administration of edaravone |
| JP7277005B2 (ja) | 2017-07-06 | 2023-05-18 | ツリーウェイ ティーダブリュー001 ビー.ブイ. | 酸化ストレス媒介性の神経変性障害の経口治療におけるエダラボンの使用 |
| US11826352B2 (en) | 2018-11-02 | 2023-11-28 | Mitsubishi Tanabe Pharma Corporation | Edaravone suspension for oral administration |
| SG11202104365QA (en) | 2018-11-02 | 2021-05-28 | Mitsubishi Tanabe Pharma Corp | Edaravone suspension for oral administration |
| US12343330B2 (en) | 2023-02-16 | 2025-07-01 | Slayback Pharma Llc | Stable pharmaceutical compositions of edaravone |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3758164B2 (ja) | 2000-10-24 | 2006-03-22 | 三菱ウェルファーマ株式会社 | 筋萎縮性側索硬化症(als)治療剤 |
| IS7278A (is) | 2001-11-26 | 2003-05-27 | Merlyn Associates, Inc. | Barkaslanga með stefnustjórnanlegum enda og stöðuhaldandi búnaði |
| CN1241565C (zh) * | 2003-04-16 | 2006-02-15 | 浙江震元制药有限公司 | 依达拉奉药物组合物及制备 |
| CN100358520C (zh) | 2003-09-11 | 2008-01-02 | 彭建华 | 具有良好稳定性的注射用依达拉奉粉针剂及其制备方法 |
| ES2673158T3 (es) | 2004-02-09 | 2018-06-20 | Mitsubishi Tanabe Pharma Corporation | Nuevo agente terapéutico para la esclerosis lateral amiotrófica (ELA) o enfermedad atribuible a ELA |
| CN101953832B (zh) | 2010-08-10 | 2012-02-15 | 南京师范大学 | β-环糊精包合依达拉奉的口服药物组合物及其制备方法 |
| CN102349893A (zh) * | 2011-08-19 | 2012-02-15 | 福建天泉药业股份有限公司 | 依达拉奉药物组合物 |
| KR20190049905A (ko) | 2011-09-05 | 2019-05-09 | 미쓰비시 타나베 파마 코퍼레이션 | 근위축성 측색경화증의 치료 또는 병세 진전 억제를 위한 약제 |
| CN103251554A (zh) | 2013-06-06 | 2013-08-21 | 南京亿华药业有限公司 | 一种稳定的依达拉奉注射液及其制备方法 |
| CN113768879A (zh) | 2016-03-16 | 2021-12-10 | 苏州澳宗生物科技有限公司 | 依达拉奉剂型 |
| AU2017394478B2 (en) | 2017-01-17 | 2023-07-20 | Treeway Tw001 B.V. | Medical treatment comprising enteral administration of edaravone |
| ES2850873T3 (es) | 2017-01-17 | 2021-09-01 | Treeway Tw001 B V | Tratamiento que comprende la administración oral o gástrica de edaravona |
| JP7277005B2 (ja) | 2017-07-06 | 2023-05-18 | ツリーウェイ ティーダブリュー001 ビー.ブイ. | 酸化ストレス媒介性の神経変性障害の経口治療におけるエダラボンの使用 |
-
2017
- 2017-07-06 AU AU2017394478A patent/AU2017394478B2/en active Active
- 2017-07-06 ES ES17737775T patent/ES2868955T3/es active Active
- 2017-07-06 EP EP17737775.1A patent/EP3570819B1/en active Active
- 2017-07-06 DK DK17737775.1T patent/DK3570819T3/da active
- 2017-07-06 CA CA3050031A patent/CA3050031A1/en active Pending
- 2017-07-06 PL PL17737775T patent/PL3570819T3/pl unknown
- 2017-07-06 MX MX2019008482A patent/MX390101B/es unknown
- 2017-07-06 PT PT177377751T patent/PT3570819T/pt unknown
- 2017-07-06 WO PCT/EP2017/067005 patent/WO2018133957A1/en not_active Ceased
- 2017-07-06 JP JP2019559159A patent/JP6898027B2/ja active Active
- 2017-07-06 BR BR112019014712-8A patent/BR112019014712A2/pt not_active Application Discontinuation
-
2019
- 2019-07-12 US US16/510,497 patent/US10966960B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PT3570819T (pt) | 2021-04-20 |
| JP6898027B2 (ja) | 2021-07-07 |
| US10966960B2 (en) | 2021-04-06 |
| EP3570819B1 (en) | 2021-03-03 |
| EP3570819A1 (en) | 2019-11-27 |
| US20190328711A1 (en) | 2019-10-31 |
| AU2017394478A1 (en) | 2019-08-01 |
| JP2020506958A (ja) | 2020-03-05 |
| CA3050031A1 (en) | 2018-07-26 |
| BR112019014712A2 (pt) | 2020-02-18 |
| PL3570819T3 (pl) | 2021-10-25 |
| ES2868955T3 (es) | 2021-10-22 |
| MX390101B (es) | 2025-03-20 |
| MX2019008482A (es) | 2019-11-11 |
| WO2018133957A1 (en) | 2018-07-26 |
| AU2017394478B2 (en) | 2023-07-20 |
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