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DK3548061T3 - Behandling af neurologiske sygdomme - Google Patents

Behandling af neurologiske sygdomme Download PDF

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Publication number
DK3548061T3
DK3548061T3 DK17811693.5T DK17811693T DK3548061T3 DK 3548061 T3 DK3548061 T3 DK 3548061T3 DK 17811693 T DK17811693 T DK 17811693T DK 3548061 T3 DK3548061 T3 DK 3548061T3
Authority
DK
Denmark
Prior art keywords
treatment
neurological diseases
neurological
diseases
Prior art date
Application number
DK17811693.5T
Other languages
English (en)
Inventor
Christian Hölscher
Original Assignee
Lancaster Univ Business Enterprises Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lancaster Univ Business Enterprises Limited filed Critical Lancaster Univ Business Enterprises Limited
Application granted granted Critical
Publication of DK3548061T3 publication Critical patent/DK3548061T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
DK17811693.5T 2016-12-05 2017-12-04 Behandling af neurologiske sygdomme DK3548061T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1620611.2A GB201620611D0 (en) 2016-12-05 2016-12-05 Treatment of neurological diseases
PCT/GB2017/053655 WO2018104718A1 (en) 2016-12-05 2017-12-04 Treatment of neurological diseases

Publications (1)

Publication Number Publication Date
DK3548061T3 true DK3548061T3 (da) 2020-12-14

Family

ID=58159786

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17811693.5T DK3548061T3 (da) 2016-12-05 2017-12-04 Behandling af neurologiske sygdomme

Country Status (26)

Country Link
US (2) US11220534B2 (da)
EP (1) EP3548061B1 (da)
JP (1) JP7099729B2 (da)
KR (1) KR102600128B1 (da)
CN (1) CN110312520B (da)
AU (1) AU2017371811B2 (da)
BR (1) BR112019011462A2 (da)
CA (1) CA3044797C (da)
CL (1) CL2019001512A1 (da)
CO (1) CO2019006979A2 (da)
CY (1) CY1123623T1 (da)
DK (1) DK3548061T3 (da)
ES (1) ES2833408T3 (da)
GB (1) GB201620611D0 (da)
HR (1) HRP20201959T1 (da)
HU (1) HUE052766T2 (da)
LT (1) LT3548061T (da)
MX (1) MX2019006495A (da)
NZ (1) NZ753881A (da)
PT (1) PT3548061T (da)
RS (1) RS61230B1 (da)
RU (1) RU2755997C2 (da)
SI (1) SI3548061T1 (da)
SM (1) SMT202000684T1 (da)
WO (1) WO2018104718A1 (da)
ZA (1) ZA201903003B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases
IL320805A (en) * 2020-01-30 2025-07-01 Lilly Co Eli Medical uses of tirazepate
CN116157143A (zh) 2020-07-22 2023-05-23 诺和诺德股份有限公司 适合于口服递送的glp-1和gip受体的共激动剂
CN116600831A (zh) * 2020-09-25 2023-08-15 韩美药品株式会社 对胰高血糖素、glp-1和glp受体全部具有活性的三重激动剂或其缀合物用于神经变性疾病的治疗用途
CN114617956B (zh) * 2020-12-10 2023-10-03 江苏中新医药有限公司 一种高效降糖的蛋白质药物
CA3220005A1 (en) 2021-05-13 2022-11-17 Carmot Therapeutics Inc. Modulators of g-protein coupled receptors
CN114042149B (zh) * 2021-12-03 2023-06-16 中国人民解放军空军军医大学 D-Ala2-GIP用于制备治疗焦虑症药物的应用
TW202330584A (zh) 2022-01-20 2023-08-01 丹麥商諾佛 儂迪克股份有限公司 前藥及其用途
WO2023151594A1 (en) * 2022-02-11 2023-08-17 Hangzhou Sciwind Biosciences Co., Ltd. A composition comprising gip receptor agonists and glp-1 receptor agonists and use thereof
WO2024209050A1 (en) 2023-04-05 2024-10-10 Antag Therapeutics Aps Gip activity modulators and orthostatic intolerance
CN119925576A (zh) * 2024-02-06 2025-05-06 上海市第四人民医院 一种治疗神经退行性疾病的药物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081792A2 (en) 2006-01-05 2007-07-19 University Of Utah Research Foundation Methods and compositions related to improving properties of pharmacological agents targeting nervous system
EA020326B9 (ru) * 2008-06-17 2015-03-31 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Агонисты смешанного действия на основе глюкозозависимого инсулинотропного пептида для лечения нарушений обмена веществ и ожирения
WO2010043047A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
EP2528618A4 (en) 2010-01-27 2015-05-27 Univ Indiana Res & Tech Corp GLUCAGON ANTAGONISTE AND GIP AGONISTS CONJUGATES AND COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES AND ADIPOSITAS
DK2621945T3 (da) 2010-09-28 2018-05-22 Nono Inc Nd2-peptider og fremgangsmåder til behandling af neurologisk sygdom
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
EP2766094B1 (en) 2011-10-10 2019-03-06 Lancaster University Business Enterprises Limited Compositions for binding to amyloid proteins
AR090937A1 (es) 2012-05-03 2014-12-17 Zealand Pharma As Compuestos agonista duales de gip-glp-1 y metodos para usarlos
JP6311708B2 (ja) * 2012-06-21 2018-04-18 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation Gip受容体活性を示すグルカゴンアナローグ
KR102605540B1 (ko) 2014-05-28 2023-11-22 노노 인코포레이티드 Tat-nr2b9c의 클로라이드 염
GB2528436A (en) * 2014-07-15 2016-01-27 Lancaster Univ Business Entpr Ltd Treatment of neurological diseases
US20160143920A1 (en) * 2014-10-22 2016-05-26 Morris Notelovitz Composition, formulations and methods of making and using botanicals and natural compounds for the promotion of healthy brain aging
US20170112897A1 (en) 2015-10-23 2017-04-27 Cedars-Sinai Medical Center Methods for treating brain insulin resistance
CA3003465A1 (en) 2015-10-28 2017-05-04 Krishna Kumar Novel polypeptides with improved proteolytic stability, and methods of preparing and using same
WO2017210168A1 (en) 2016-06-02 2017-12-07 Indiana University Research And Technology Corporation Aqueously soluble and chemically stable depsi glucagon agonists
GB201620611D0 (en) * 2016-12-05 2017-01-18 Univ Of Lancaster Treatment of neurological diseases

Also Published As

Publication number Publication date
US11851468B2 (en) 2023-12-26
SI3548061T1 (sl) 2021-04-30
US11220534B2 (en) 2022-01-11
US20220033457A1 (en) 2022-02-03
AU2017371811B2 (en) 2022-03-10
JP2020504713A (ja) 2020-02-13
RS61230B1 (sr) 2021-01-29
EP3548061B1 (en) 2020-09-09
ES2833408T3 (es) 2021-06-15
KR20190101367A (ko) 2019-08-30
JP7099729B2 (ja) 2022-07-12
CA3044797A1 (en) 2018-06-14
CL2019001512A1 (es) 2019-11-22
RU2019118165A3 (da) 2021-03-05
CO2019006979A2 (es) 2019-09-09
RU2019118165A (ru) 2021-01-11
LT3548061T (lt) 2020-12-28
KR102600128B1 (ko) 2023-11-08
CN110312520A (zh) 2019-10-08
HRP20201959T1 (hr) 2021-04-16
PT3548061T (pt) 2020-11-24
AU2017371811A1 (en) 2019-06-13
HUE052766T2 (hu) 2021-05-28
WO2018104718A1 (en) 2018-06-14
CN110312520B (zh) 2023-01-24
RU2755997C2 (ru) 2021-09-24
BR112019011462A2 (pt) 2019-10-22
MX2019006495A (es) 2019-11-05
NZ753881A (en) 2025-08-29
SMT202000684T1 (it) 2021-01-05
GB201620611D0 (en) 2017-01-18
US20200079832A1 (en) 2020-03-12
EP3548061A1 (en) 2019-10-09
CY1123623T1 (el) 2022-03-24
CA3044797C (en) 2025-05-20
ZA201903003B (en) 2019-12-18

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