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DK3459538T3 - Krystallinske salte af et dextroamfetamin-prodrug - Google Patents

Krystallinske salte af et dextroamfetamin-prodrug Download PDF

Info

Publication number
DK3459538T3
DK3459538T3 DK17192115.8T DK17192115T DK3459538T3 DK 3459538 T3 DK3459538 T3 DK 3459538T3 DK 17192115 T DK17192115 T DK 17192115T DK 3459538 T3 DK3459538 T3 DK 3459538T3
Authority
DK
Denmark
Prior art keywords
crystalline salts
dextroamphetamine
prodrug
dextroamphetamine prodrug
crystalline
Prior art date
Application number
DK17192115.8T
Other languages
English (en)
Inventor
Hannes Lengauer
Arthur Pichler
Renate Margreiter
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of DK3459538T3 publication Critical patent/DK3459538T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/541Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK17192115.8T 2017-09-20 2017-09-20 Krystallinske salte af et dextroamfetamin-prodrug DK3459538T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17192115.8A EP3459538B1 (en) 2017-09-20 2017-09-20 Crystalline salts of a dextroamphetamine prodrug

Publications (1)

Publication Number Publication Date
DK3459538T3 true DK3459538T3 (da) 2020-08-03

Family

ID=59955377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17192115.8T DK3459538T3 (da) 2017-09-20 2017-09-20 Krystallinske salte af et dextroamfetamin-prodrug

Country Status (4)

Country Link
EP (1) EP3459538B1 (da)
DK (1) DK3459538T3 (da)
ES (1) ES2806995T3 (da)
WO (1) WO2019057765A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024003797A1 (en) * 2022-06-30 2024-01-04 Ind-Swift Laboratories Limited Crystalline salts of lisdexamfetamine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1493824A1 (de) * 1964-01-27 1969-05-22 Hoffmann La Roche Verfahren zur Herstellung von Aminocarbonsaeureamiden
WO2006121552A2 (en) 2005-04-08 2006-11-16 New River Pharmaceuticals Inc. Abuse-resistant amphetamine prodrugs
NZ544162A (en) 2003-05-29 2008-09-26 Shire Llc Abuse resistant amphetamine compounds
US8614346B2 (en) 2009-06-19 2013-12-24 Cambrex Charles City, Inc. Methods and compositions for preparation of amphetamine conjugates and salts thereof
WO2014168727A1 (en) 2013-03-15 2014-10-16 Shire Llc Fixed dose combination treatment for schizophrenia
US10544434B2 (en) 2015-06-29 2020-01-28 Noramco, Inc. Process for the preparation of lisdexamfetamine and related derivatives

Also Published As

Publication number Publication date
EP3459538B1 (en) 2020-05-06
EP3459538A1 (en) 2019-03-27
ES2806995T3 (es) 2021-02-19
WO2019057765A1 (en) 2019-03-28

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