DK3459538T3 - Krystallinske salte af et dextroamfetamin-prodrug - Google Patents
Krystallinske salte af et dextroamfetamin-prodrug Download PDFInfo
- Publication number
- DK3459538T3 DK3459538T3 DK17192115.8T DK17192115T DK3459538T3 DK 3459538 T3 DK3459538 T3 DK 3459538T3 DK 17192115 T DK17192115 T DK 17192115T DK 3459538 T3 DK3459538 T3 DK 3459538T3
- Authority
- DK
- Denmark
- Prior art keywords
- crystalline salts
- dextroamphetamine
- prodrug
- dextroamphetamine prodrug
- crystalline
- Prior art date
Links
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 title 1
- 229960000632 dexamfetamine Drugs 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17192115.8A EP3459538B1 (en) | 2017-09-20 | 2017-09-20 | Crystalline salts of a dextroamphetamine prodrug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3459538T3 true DK3459538T3 (da) | 2020-08-03 |
Family
ID=59955377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17192115.8T DK3459538T3 (da) | 2017-09-20 | 2017-09-20 | Krystallinske salte af et dextroamfetamin-prodrug |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3459538B1 (da) |
| DK (1) | DK3459538T3 (da) |
| ES (1) | ES2806995T3 (da) |
| WO (1) | WO2019057765A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024003797A1 (en) * | 2022-06-30 | 2024-01-04 | Ind-Swift Laboratories Limited | Crystalline salts of lisdexamfetamine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1493824A1 (de) * | 1964-01-27 | 1969-05-22 | Hoffmann La Roche | Verfahren zur Herstellung von Aminocarbonsaeureamiden |
| WO2006121552A2 (en) | 2005-04-08 | 2006-11-16 | New River Pharmaceuticals Inc. | Abuse-resistant amphetamine prodrugs |
| NZ544162A (en) | 2003-05-29 | 2008-09-26 | Shire Llc | Abuse resistant amphetamine compounds |
| US8614346B2 (en) | 2009-06-19 | 2013-12-24 | Cambrex Charles City, Inc. | Methods and compositions for preparation of amphetamine conjugates and salts thereof |
| WO2014168727A1 (en) | 2013-03-15 | 2014-10-16 | Shire Llc | Fixed dose combination treatment for schizophrenia |
| US10544434B2 (en) | 2015-06-29 | 2020-01-28 | Noramco, Inc. | Process for the preparation of lisdexamfetamine and related derivatives |
-
2017
- 2017-09-20 DK DK17192115.8T patent/DK3459538T3/da active
- 2017-09-20 ES ES17192115T patent/ES2806995T3/es active Active
- 2017-09-20 EP EP17192115.8A patent/EP3459538B1/en active Active
-
2018
- 2018-09-19 WO PCT/EP2018/075338 patent/WO2019057765A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3459538B1 (en) | 2020-05-06 |
| EP3459538A1 (en) | 2019-03-27 |
| ES2806995T3 (es) | 2021-02-19 |
| WO2019057765A1 (en) | 2019-03-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3472157T3 (da) | Krystallinske faste former af en bet-inhibitor | |
| DK3844407T3 (da) | Sæt af plader med en mekanisk låseanordning | |
| DK3978483T3 (da) | Krystallinsk toluensolvat af (s)-afoxolaner | |
| DK3334709T3 (da) | Salte af en lsd1-hæmmer | |
| DK3541807T3 (da) | Krystallinsk form af en magl-inhibitor | |
| DK3371171T3 (da) | Inhibitorer af RET | |
| DK3226763T3 (da) | Billeddannelse af en krop | |
| IL286218A (en) | Solid state forms of ripretinib | |
| DK3558159T3 (da) | Sporingselementer til sporing af bevægelser af hårdt væv af en kæbe | |
| DK3353175T3 (da) | Salte og faste former af et monobactam-antibiotikum | |
| DK3798222T3 (da) | Krystallinsk form af den frie base af lorlatinib | |
| DK3475367T3 (da) | Fremstilling af strukturnet af krystallinsk carbon | |
| DK3365323T3 (da) | Salte af tetracycliner | |
| EP3718688A4 (en) | MACHINE-TOOL TOOL STORE MODULE | |
| DK3692039T3 (da) | Enantiomerer af substituerede thiazoler som antivirale forbindelser | |
| DK3717503T3 (da) | Albumin-bindende prodrugs af auristatin E derivater | |
| HUE050553T2 (hu) | Eljárás A módosulatú kalkobutrol kristályos alakjának elõállítására | |
| DK3433354T3 (da) | Generering af syntetiske genomer | |
| DK3668835T3 (da) | Fremgangsmåde til fremstilling af en monothiocarbonatforbindelse | |
| LT3597189T (lt) | Kristaliniai junginia | |
| DK3424122T3 (da) | Strømstyring af et mikronet | |
| DK3289175T3 (da) | Rørformet borehulsenhed af en rørformet brøndkonstruktion | |
| EP3829551C0 (en) | CRYSTALLINE EPINEPHRINE MALONATE SALT | |
| EP4277621A4 (en) | CRYSTALLINE BUFOTENIDINE COMPOUNDS | |
| DK3749673T3 (da) | Krystallinsk form af bictegravir-natrium |