DK3452515T3 - Her-2-bindende antistoffer - Google Patents
Her-2-bindende antistofferInfo
- Publication number
- DK3452515T3 DK3452515T3 DK17724779.8T DK17724779T DK3452515T3 DK 3452515 T3 DK3452515 T3 DK 3452515T3 DK 17724779 T DK17724779 T DK 17724779T DK 3452515 T3 DK3452515 T3 DK 3452515T3
- Authority
- DK
- Denmark
- Prior art keywords
- binding antibodies
- antibodies
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16168619.1A EP3241847A1 (en) | 2016-05-06 | 2016-05-06 | Her-2 binding antibodies |
| PCT/EP2017/060935 WO2017191327A2 (en) | 2016-05-06 | 2017-05-08 | Her-2 binding antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3452515T3 true DK3452515T3 (da) | 2025-11-17 |
Family
ID=55919722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17724779.8T DK3452515T3 (da) | 2016-05-06 | 2017-05-08 | Her-2-bindende antistoffer |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11091561B2 (da) |
| EP (3) | EP3241847A1 (da) |
| JP (1) | JP6964127B2 (da) |
| CN (1) | CN109415443B (da) |
| AU (1) | AU2017260684B2 (da) |
| CA (2) | CA3022650C (da) |
| DK (1) | DK3452515T3 (da) |
| FI (1) | FI3452515T3 (da) |
| LT (1) | LT3452515T (da) |
| NZ (1) | NZ747774A (da) |
| PT (1) | PT3452515T (da) |
| WO (1) | WO2017191327A2 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3241847A1 (en) * | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Her-2 binding antibodies |
| SG10201801219VA (en) * | 2018-02-13 | 2019-09-27 | Agency Science Tech & Res | Anti-HER2 Antibodies |
| AU2020247828A1 (en) * | 2019-03-22 | 2021-11-18 | Certis Therapeutics Pty Ltd | Anti-HER2 binding molecules |
| CN113924116B (zh) * | 2019-05-02 | 2025-11-25 | Mab发现股份有限公司 | Her2抗体的组合 |
| EP4337332A2 (en) * | 2021-07-13 | 2024-03-20 | Mabwell Therapeutics Inc. | Anti-c1s antibodies and uses thereof |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0940468A1 (en) * | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
| JP4308470B2 (ja) * | 1999-07-30 | 2009-08-05 | メダレックス インク | 抗Ｆｃ受容体結合薬からなる治療用化合物 |
| US20080071063A1 (en) | 2006-02-03 | 2008-03-20 | Medimmune, Inc. | Protein Formulations |
| TWI472339B (zh) * | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物 |
| JP6082344B2 (ja) * | 2010-05-27 | 2017-02-15 | ゲンマブ エー／エス | Ｈｅｒ２エピトープに対するモノクローナル抗体 |
| WO2011147986A1 (en) | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
| US9527913B2 (en) * | 2012-05-02 | 2016-12-27 | Symphogen A/S | Humanized pan-HER antibody compositions |
| KR101453462B1 (ko) | 2013-05-16 | 2014-10-23 | 앱클론(주) | Her2에 특이적으로 결합하는 항체 |
| WO2016040848A1 (en) * | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
| EP3241847A1 (en) * | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Her-2 binding antibodies |
-
2016
- 2016-05-06 EP EP16168619.1A patent/EP3241847A1/en not_active Withdrawn
-
2017
- 2017-05-08 CA CA3022650A patent/CA3022650C/en active Active
- 2017-05-08 CN CN201780041578.3A patent/CN109415443B/zh active Active
- 2017-05-08 AU AU2017260684A patent/AU2017260684B2/en active Active
- 2017-05-08 US US16/099,228 patent/US11091561B2/en active Active
- 2017-05-08 DK DK17724779.8T patent/DK3452515T3/da active
- 2017-05-08 EP EP25189847.4A patent/EP4613334A2/en active Pending
- 2017-05-08 NZ NZ747774A patent/NZ747774A/en unknown
- 2017-05-08 JP JP2019510474A patent/JP6964127B2/ja active Active
- 2017-05-08 CA CA3278826A patent/CA3278826A1/en active Pending
- 2017-05-08 LT LTEPPCT/EP2017/060935T patent/LT3452515T/lt unknown
- 2017-05-08 PT PT177247798T patent/PT3452515T/pt unknown
- 2017-05-08 EP EP17724779.8A patent/EP3452515B1/en active Active
- 2017-05-08 WO PCT/EP2017/060935 patent/WO2017191327A2/en not_active Ceased
- 2017-05-08 FI FIEP17724779.8T patent/FI3452515T3/fi active
-
2021
- 2021-07-14 US US17/375,793 patent/US12129307B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| LT3452515T (lt) | 2025-12-10 |
| AU2017260684A1 (en) | 2018-11-29 |
| EP3452515B1 (en) | 2025-08-20 |
| US20190241674A1 (en) | 2019-08-08 |
| JP2019516788A (ja) | 2019-06-20 |
| EP3452515A2 (en) | 2019-03-13 |
| AU2017260684B2 (en) | 2024-05-09 |
| PT3452515T (pt) | 2025-11-27 |
| US12129307B2 (en) | 2024-10-29 |
| EP3241847A1 (en) | 2017-11-08 |
| NZ747774A (en) | 2022-07-01 |
| WO2017191327A3 (en) | 2017-12-14 |
| US20210395389A1 (en) | 2021-12-23 |
| CA3022650C (en) | 2025-09-23 |
| EP4613334A2 (en) | 2025-09-10 |
| US11091561B2 (en) | 2021-08-17 |
| CA3278826A1 (en) | 2025-11-29 |
| WO2017191327A2 (en) | 2017-11-09 |
| FI3452515T3 (fi) | 2025-11-25 |
| CN109415443A (zh) | 2019-03-01 |
| CN109415443B (zh) | 2021-10-29 |
| CA3022650A1 (en) | 2017-11-09 |
| JP6964127B2 (ja) | 2021-11-10 |
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