DK3382019T3 - Fremgangsmåde til omdannelse af enkimet plantegenomsekvens, hvori nukleinsyrebase i målrettet DNA-sekvens specifikt omdannes, og molekylært kompleks anvendt deri - Google Patents
Fremgangsmåde til omdannelse af enkimet plantegenomsekvens, hvori nukleinsyrebase i målrettet DNA-sekvens specifikt omdannes, og molekylært kompleks anvendt deri Download PDFInfo
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- DK3382019T3 DK3382019T3 DK16868704.4T DK16868704T DK3382019T3 DK 3382019 T3 DK3382019 T3 DK 3382019T3 DK 16868704 T DK16868704 T DK 16868704T DK 3382019 T3 DK3382019 T3 DK 3382019T3
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- Denmark
- Prior art keywords
- converting
- nucleic acid
- specific dna
- acid base
- molecular complex
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- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8205—Agrobacterium mediated transformation
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- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12N2523/00—Culture process characterised by temperature
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- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
- C12Y305/04005—Cytidine deaminase (3.5.4.5)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015232379 | 2015-11-27 | ||
| JP2016134613 | 2016-07-06 | ||
| PCT/JP2016/085075 WO2017090761A1 (ja) | 2015-11-27 | 2016-11-25 | 標的化したdna配列の核酸塩基を特異的に変換する、単子葉植物のゲノム配列の変換方法、及びそれに用いる分子複合体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3382019T3 true DK3382019T3 (da) | 2022-05-30 |
Family
ID=58764366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16868704.4T DK3382019T3 (da) | 2015-11-27 | 2016-11-25 | Fremgangsmåde til omdannelse af enkimet plantegenomsekvens, hvori nukleinsyrebase i målrettet DNA-sekvens specifikt omdannes, og molekylært kompleks anvendt deri |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11220693B2 (da) |
| EP (1) | EP3382019B1 (da) |
| JP (1) | JP6923205B2 (da) |
| KR (1) | KR102061438B1 (da) |
| CN (1) | CN108495932B (da) |
| DK (1) | DK3382019T3 (da) |
| ES (1) | ES2914623T3 (da) |
| WO (1) | WO2017090761A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111471674A (zh) | 2014-03-05 | 2020-07-31 | 国立大学法人神户大学 | 特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体 |
| JP6664693B2 (ja) * | 2015-09-09 | 2020-03-13 | 国立大学法人神戸大学 | 標的化したdna配列の核酸塩基を特異的に変換する、グラム陽性菌のゲノム配列の変換方法、及びそれに用いる分子複合体 |
| EP3382019B1 (en) | 2015-11-27 | 2022-05-04 | National University Corporation Kobe University | Method for converting monocot plant genome sequence in which nucleic acid base in targeted dna sequence is specifically converted, and molecular complex used therein |
| SG11201809242VA (en) * | 2016-04-21 | 2018-11-29 | Univ Kobe Nat Univ Corp | Method for increasing mutation introduction efficiency in genome sequence modification technique, and molecular complex to be used therefor |
| WO2017195905A1 (ja) | 2016-05-13 | 2017-11-16 | 株式会社カネカ | 形質転換植物の作製方法 |
| WO2017195906A1 (ja) | 2016-05-13 | 2017-11-16 | 株式会社カネカ | 植物のゲノム編集方法 |
| US11499158B2 (en) | 2016-05-13 | 2022-11-15 | Kaneka Corporation | Method for modifying plant |
| CN107043779B (zh) * | 2016-12-01 | 2020-05-12 | 中国农业科学院作物科学研究所 | 一种CRISPR/nCas9介导的定点碱基替换在植物中的应用 |
| WO2018143477A1 (ja) * | 2017-02-06 | 2018-08-09 | 国立大学法人 筑波大学 | 双子葉植物のゲノムの改変方法 |
| CN110157727A (zh) * | 2017-12-21 | 2019-08-23 | 中国科学院遗传与发育生物学研究所 | 植物碱基编辑方法 |
| CA3095291C (en) * | 2018-03-26 | 2022-10-11 | National University Corporation Kobe University | Method for modifying target site in double-stranded dna in cell |
| WO2019213910A1 (en) * | 2018-05-10 | 2019-11-14 | Syngenta Participations Ag | Methods and compositions for targeted editing of polynucleotides |
| JP7541508B2 (ja) * | 2018-08-23 | 2024-08-28 | サンガモ セラピューティクス, インコーポレイテッド | 操作された標的特異的な塩基エディター |
| CN110607320B (zh) * | 2018-11-23 | 2023-05-12 | 电子科技大学 | 一种植物基因组定向碱基编辑骨架载体及其应用 |
| CN110257406B (zh) * | 2019-06-21 | 2022-07-22 | 安徽省农业科学院水稻研究所 | 密码子植物化改造的Plant Nme2Cas9基因及其应用 |
| WO2021046155A1 (en) | 2019-09-03 | 2021-03-11 | Voyager Therapeutics, Inc. | Vectorized editing of nucleic acids to correct overt mutations |
| JP7616514B2 (ja) * | 2019-09-10 | 2025-01-17 | 株式会社カネカ | 腋芽メリステムを用いた植物の改変方法 |
| EP4086353A4 (en) * | 2020-01-03 | 2024-03-06 | Kaneka Corporation | METHOD FOR PLANT MODIFICATION |
| WO2022158561A1 (ja) * | 2021-01-22 | 2022-07-28 | 国立大学法人東京大学 | 植物ゲノムの編集方法 |
| CN117157399A (zh) * | 2021-02-26 | 2023-12-01 | 国立大学法人神户大学 | 植物基因组进化工程半理性方法 |
| US20240240196A1 (en) * | 2021-05-26 | 2024-07-18 | The Board Of Trustees Of The University Of Illinois | C4 plants with increased photosynthetic efficiency |
| US20240279719A1 (en) * | 2021-06-17 | 2024-08-22 | The Board Of Trustees Of The University Of Illinois | Crispr cascade |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2003524368A (ja) | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、dna結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
| WO2003087341A2 (en) | 2002-01-23 | 2003-10-23 | The University Of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
| NZ579002A (en) | 2007-03-02 | 2012-03-30 | Danisco | Cultures with improved phage resistance |
| WO2010132092A2 (en) | 2009-05-12 | 2010-11-18 | The Scripps Research Institute | Cytidine deaminase fusions and related methods |
| US8772008B2 (en) | 2009-05-18 | 2014-07-08 | Sangamo Biosciences, Inc. | Methods and compositions for increasing nuclease activity |
| US20110104787A1 (en) | 2009-11-05 | 2011-05-05 | President And Fellows Of Harvard College | Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences |
| CA2783351C (en) | 2009-12-10 | 2021-09-07 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| JP2013128413A (ja) | 2010-03-11 | 2013-07-04 | Kyushu Univ | Pprモチーフを利用したrna結合性蛋白質の改変方法 |
| WO2013058404A1 (ja) | 2011-10-21 | 2013-04-25 | 国立大学法人九州大学 | Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用 |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
| SG10201607943RA (en) | 2012-03-23 | 2016-11-29 | Cellectis | Method to overcome dna chemical modifications sensitivity of engineered tale dna binding domains |
| FI3597749T3 (fi) | 2012-05-25 | 2023-10-09 | Univ California | Menetelmiä ja koostumuksia rna-ohjattua kohde-dna-modifikaatiota varten ja rna-ohjattua transkription modulaatiota varten |
| WO2014071235A1 (en) | 2012-11-01 | 2014-05-08 | Massachusetts Institute Of Technology | Genetic device for the controlled destruction of dna |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| PT2784162E (pt) | 2012-12-12 | 2015-08-27 | Broad Inst Inc | Engenharia de sistemas, métodos e composições guia otimizadas para a manipulação de sequências |
| EP4234696A3 (en) * | 2012-12-12 | 2023-09-06 | The Broad Institute Inc. | Crispr-cas component systems, methods and compositions for sequence manipulation |
| WO2014165612A2 (en) | 2013-04-05 | 2014-10-09 | Dow Agrosciences Llc | Methods and compositions for integration of an exogenous sequence within the genome of plants |
| US9873907B2 (en) * | 2013-05-29 | 2018-01-23 | Agilent Technologies, Inc. | Method for fragmenting genomic DNA using CAS9 |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| CN111471674A (zh) | 2014-03-05 | 2020-07-31 | 国立大学法人神户大学 | 特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体 |
| EP4427809A3 (en) | 2014-10-31 | 2024-12-04 | The Trustees of The University of Pennsylvania | Altering gene expression in car-t cells and uses thereof |
| EP3216867B1 (en) | 2014-11-04 | 2020-04-15 | National University Corporation Kobe University | Method for modifying genome sequence to introduce specific mutation to targeted dna sequence by base-removal reaction, and molecular complex used therein |
| JP6664693B2 (ja) | 2015-09-09 | 2020-03-13 | 国立大学法人神戸大学 | 標的化したdna配列の核酸塩基を特異的に変換する、グラム陽性菌のゲノム配列の変換方法、及びそれに用いる分子複合体 |
| SG11201801809VA (en) | 2015-09-09 | 2018-04-27 | Univ Kobe Nat Univ Corp | Method for modifying genome sequence that specifically converts nucleobase of targeted dna sequence, and molecular complex used in said method |
| US12043852B2 (en) * | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| EP3382019B1 (en) | 2015-11-27 | 2022-05-04 | National University Corporation Kobe University | Method for converting monocot plant genome sequence in which nucleic acid base in targeted dna sequence is specifically converted, and molecular complex used therein |
| SG11201809242VA (en) | 2016-04-21 | 2018-11-29 | Univ Kobe Nat Univ Corp | Method for increasing mutation introduction efficiency in genome sequence modification technique, and molecular complex to be used therefor |
-
2016
- 2016-11-25 EP EP16868704.4A patent/EP3382019B1/en active Active
- 2016-11-25 WO PCT/JP2016/085075 patent/WO2017090761A1/ja not_active Ceased
- 2016-11-25 DK DK16868704.4T patent/DK3382019T3/da active
- 2016-11-25 CN CN201680079887.5A patent/CN108495932B/zh active Active
- 2016-11-25 JP JP2017552750A patent/JP6923205B2/ja active Active
- 2016-11-25 KR KR1020187017539A patent/KR102061438B1/ko active Active
- 2016-11-25 US US15/779,120 patent/US11220693B2/en active Active
- 2016-11-25 ES ES16868704T patent/ES2914623T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017090761A1 (ja) | 2017-06-01 |
| KR102061438B1 (ko) | 2019-12-31 |
| EP3382019A1 (en) | 2018-10-03 |
| CN108495932B (zh) | 2022-08-09 |
| BR112018010681A2 (pt) | 2018-11-13 |
| EP3382019A4 (en) | 2019-04-24 |
| EP3382019B1 (en) | 2022-05-04 |
| ES2914623T3 (es) | 2022-06-14 |
| US20190085342A1 (en) | 2019-03-21 |
| BR112018010681A8 (pt) | 2019-02-26 |
| HK1256888A1 (en) | 2019-10-04 |
| JPWO2017090761A1 (ja) | 2018-10-25 |
| CN108495932A (zh) | 2018-09-04 |
| JP6923205B2 (ja) | 2021-08-18 |
| KR20180081811A (ko) | 2018-07-17 |
| US11220693B2 (en) | 2022-01-11 |
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