DK3375890T3 - Fremgangsmåder og indretninger til at bestemme en krydstalekorrektion i nukleinsyreamplifikation - Google Patents
Fremgangsmåder og indretninger til at bestemme en krydstalekorrektion i nukleinsyreamplifikation Download PDFInfo
- Publication number
- DK3375890T3 DK3375890T3 DK18169032.2T DK18169032T DK3375890T3 DK 3375890 T3 DK3375890 T3 DK 3375890T3 DK 18169032 T DK18169032 T DK 18169032T DK 3375890 T3 DK3375890 T3 DK 3375890T3
- Authority
- DK
- Denmark
- Prior art keywords
- determining
- methods
- devices
- nucleic acid
- acid amplification
- Prior art date
Links
- 230000003321 amplification Effects 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003199 nucleic acid amplification method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Algebra (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Analysis (AREA)
- Mathematical Optimization (AREA)
- Mathematical Physics (AREA)
- Pure & Applied Mathematics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24130709P | 2009-09-10 | 2009-09-10 | |
| US35828710P | 2010-06-24 | 2010-06-24 | |
| EP10815913.8A EP2475788B1 (en) | 2009-09-10 | 2010-08-31 | Compensation for spectral crosstalk in multiplex nucleic acid amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3375890T3 true DK3375890T3 (da) | 2020-04-14 |
Family
ID=43732754
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10815913.8T DK2475788T3 (da) | 2009-09-10 | 2010-08-31 | Kompensation for spektral krydstale i multipleks-nukleinsyreamplifikation |
| DK18169040.5T DK3375891T3 (da) | 2009-09-10 | 2010-08-31 | Fremgangsmåder og indretninger til kompensation af spektral krydstale i multipleks-nukleinsyreamplifikation |
| DK18169032.2T DK3375890T3 (da) | 2009-09-10 | 2010-08-31 | Fremgangsmåder og indretninger til at bestemme en krydstalekorrektion i nukleinsyreamplifikation |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10815913.8T DK2475788T3 (da) | 2009-09-10 | 2010-08-31 | Kompensation for spektral krydstale i multipleks-nukleinsyreamplifikation |
| DK18169040.5T DK3375891T3 (da) | 2009-09-10 | 2010-08-31 | Fremgangsmåder og indretninger til kompensation af spektral krydstale i multipleks-nukleinsyreamplifikation |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9938569B2 (da) |
| EP (3) | EP2475788B1 (da) |
| CN (1) | CN102482720B (da) |
| DK (3) | DK2475788T3 (da) |
| ES (3) | ES2791369T3 (da) |
| MX (1) | MX352971B (da) |
| PT (3) | PT2475788T (da) |
| WO (1) | WO2011031585A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2722484A1 (en) | 2008-04-24 | 2009-10-29 | Peter D. Ludowise | Analysis of nucleic acid amplification curves using wavelet transformation |
| PT2475788T (pt) * | 2009-09-10 | 2018-07-24 | Diasorin S P A | Compensação de diafonia espectral em amplificação de ácidos nucleicos multiplex |
| EP2809813B1 (en) | 2012-02-03 | 2018-08-08 | California Institute of Technology | Signal encoding and decoding in multiplexed biochemical assays |
| KR101969846B1 (ko) | 2012-06-28 | 2019-04-17 | 삼성전자주식회사 | Ｐｃｒ 데이터 및 다른 데이터에서 크로스토크의 영향을 보상하여 핵산을 분석하는 방법 및 장치 |
| CN104662172B (zh) | 2012-08-03 | 2018-07-06 | 加州理工学院 | Pcr中具有减少的硬件和要求的多重化和定量 |
| US8858886B1 (en) | 2013-05-08 | 2014-10-14 | Agilent Technologies, Inc. | Scanning system with interchangeable optical cartridges for fluorescence measurements |
| US9170198B2 (en) | 2013-12-19 | 2015-10-27 | Luminex Corporation | Crosstalk reduction |
| BE1022048B1 (nl) * | 2014-04-11 | 2016-02-10 | Ugentec Bvba | Methoden voor fluorescentie data correctie |
| ES2899739T3 (es) * | 2014-08-27 | 2022-03-14 | Hoffmann La Roche | Un procedimiento de análisis y sistema para analizar una reacción de amplificación de ácido nucleico |
| CN107426044B (zh) * | 2016-05-23 | 2022-06-07 | 中兴通讯股份有限公司 | 一种串线检测方法、装置及操作维护服务器 |
| CN109642252A (zh) | 2016-06-17 | 2019-04-16 | 加州理工学院 | 核酸反应及相关方法和组合物 |
| WO2018077739A1 (en) | 2016-10-25 | 2018-05-03 | Qiagen Gmbh | Cross-talk compensation |
| US10623132B2 (en) * | 2018-03-06 | 2020-04-14 | J3 Technology LLC | Barrage jammer with contoured amplitude |
| WO2019204357A1 (en) | 2018-04-17 | 2019-10-24 | ChromaCode, Inc. | Methods and systems for multiplex analysis |
| CN108841939B (zh) * | 2018-06-21 | 2020-09-22 | 北京致雨生物科技有限公司 | 多重数字pcr浓度测量方法及微滴式数字pcr系统 |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| WO2022020729A2 (en) * | 2020-07-23 | 2022-01-27 | Life Technologies Corporation | Systems and methods for biological analysis |
| CN111849758A (zh) * | 2020-08-18 | 2020-10-30 | 上海基灵生物科技有限公司 | 全自动实时荧光定量pcr检测系统 |
| CN113174326B (zh) * | 2021-01-15 | 2021-12-10 | 北京中科生仪科技有限公司 | 基于pcr的纯化扩增反应中的控制装置 |
| CN114752663B (zh) * | 2022-05-18 | 2024-04-30 | 苏州国科芯感医疗科技有限公司 | 一种荧光串扰校正方法及其应用 |
| US20240328948A1 (en) * | 2023-03-31 | 2024-10-03 | Araceli Biosciences Inc. | Systems and methods for fluorescence microscopy channel crosstalk mitigation |
| EP4481058A1 (en) * | 2023-06-23 | 2024-12-25 | QIAGEN GmbH | Method, use and device for signal collection in a process utilizing fluorescence at different wavelengths |
| WO2025012430A1 (en) * | 2023-07-13 | 2025-01-16 | Curetis Gmbh | Radiation transfer unit and device comprising the same |
| CN117434044B (zh) * | 2023-12-19 | 2024-03-08 | 鲲鹏基因（北京）科技有限责任公司 | 一种pcr仪荧光串扰系数标定方法及装置与应用 |
| WO2025230707A1 (en) * | 2024-05-02 | 2025-11-06 | Gen-Probe Incorporated | Adaptive crosstalk compensation of optical signal detection |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7133726B1 (en) | 1997-03-28 | 2006-11-07 | Applera Corporation | Thermal cycler for PCR |
| US6303305B1 (en) | 1999-03-30 | 2001-10-16 | Roche Diagnostics, Gmbh | Method for quantification of an analyte |
| US6156465A (en) * | 1999-04-12 | 2000-12-05 | Cymbolic Sciences Inc. | Crosstalk correction |
| US6333501B1 (en) | 2000-01-27 | 2001-12-25 | Perkin-Elmer Corporation | Methods, apparatus, and articles of manufacture for performing spectral calibration |
| US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
| US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
| US7188030B2 (en) | 2001-08-21 | 2007-03-06 | Applera Corporation | Automatic threshold setting for quantitative polymerase chain reaction |
| US7435602B2 (en) | 2002-12-20 | 2008-10-14 | Applied Biosystems Inc. | Reducing effects of spectral nonuniformity |
| US7788039B2 (en) * | 2003-09-25 | 2010-08-31 | Roche Molecular Systems, Inc. | Quantitation of nucleic acids using growth curves |
| US7177023B2 (en) | 2004-03-19 | 2007-02-13 | Applera Corporation | Fluorescent light detection |
| US7023451B2 (en) * | 2004-06-14 | 2006-04-04 | Sharp Laboratories Of America, Inc. | System for reducing crosstalk |
| US7045756B2 (en) | 2004-08-05 | 2006-05-16 | Applera Corporation | Methods and systems for in situ calibration of imaging in biological analysis |
| US20060051796A1 (en) * | 2004-09-09 | 2006-03-09 | Inga Boell | Real time PCR with the addition of pyrophosphatase |
| CN101156059B (zh) * | 2005-04-01 | 2011-06-08 | 3M创新有限公司 | 具有将多个光学模块连接到公共检测器的纤维束的多重荧光检测装置 |
| US7507575B2 (en) | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
| US7709249B2 (en) | 2005-04-01 | 2010-05-04 | 3M Innovative Properties Company | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
| US20060286587A1 (en) | 2005-06-15 | 2006-12-21 | Gen-Probe Incorporated | Methods for quantitative analysis of a nucleic acid amplification reaction |
| US20060291706A1 (en) | 2005-06-23 | 2006-12-28 | Applera Corporation | Method of extracting intensity data from digitized image |
| US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
| US7527763B2 (en) | 2005-07-05 | 2009-05-05 | 3M Innovative Properties Company | Valve control system for a rotating multiplex fluorescence detection device |
| US20070009382A1 (en) | 2005-07-05 | 2007-01-11 | William Bedingham | Heating element for a rotating multiplex fluorescence detection device |
| US7630849B2 (en) | 2005-09-01 | 2009-12-08 | Applied Biosystems, Llc | Method of automated calibration and diagnosis of laboratory instruments |
| US20070098594A1 (en) | 2005-11-03 | 2007-05-03 | Roche Molecular Systems, Inc. | Analytical multi-spectral optical detection system |
| US7680868B2 (en) | 2005-12-20 | 2010-03-16 | Roche Molecular Systems, Inc. | PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization |
| US20080033677A1 (en) | 2006-06-27 | 2008-02-07 | Applera Corporation | Methods And System For Compensating For Spatial Cross-Talk |
| EP2044432B1 (en) * | 2006-06-28 | 2023-03-29 | Life Technologies Corporation | Minimizing effects of dye crosstalk |
| US20080154512A1 (en) | 2006-07-01 | 2008-06-26 | Harrison Leong | Systems and methods for baselining and real-time pcr data analysis |
| US20080182263A1 (en) | 2007-01-29 | 2008-07-31 | Applera Corporation | Systems and Methods for Calibration Using Dye Signal Amplification |
| WO2009003645A1 (en) * | 2007-06-29 | 2009-01-08 | Roche Diagnostics Gmbh | Systems and methods for determining cross-talk coefficients in pcr and other data sets |
| US8339333B2 (en) | 2008-01-02 | 2012-12-25 | 3M Innovative Properties Company | Methods of reducing perceived image crosstalk in a multiview display |
| CA2722484A1 (en) | 2008-04-24 | 2009-10-29 | Peter D. Ludowise | Analysis of nucleic acid amplification curves using wavelet transformation |
| PT2475788T (pt) * | 2009-09-10 | 2018-07-24 | Diasorin S P A | Compensação de diafonia espectral em amplificação de ácidos nucleicos multiplex |
-
2010
- 2010-08-31 PT PT108159138T patent/PT2475788T/pt unknown
- 2010-08-31 ES ES18169040T patent/ES2791369T3/es active Active
- 2010-08-31 CN CN201080040425.5A patent/CN102482720B/zh active Active
- 2010-08-31 WO PCT/US2010/047265 patent/WO2011031585A1/en not_active Ceased
- 2010-08-31 EP EP10815913.8A patent/EP2475788B1/en active Active
- 2010-08-31 ES ES18169032T patent/ES2785672T3/es active Active
- 2010-08-31 EP EP18169032.2A patent/EP3375890B1/en active Active
- 2010-08-31 DK DK10815913.8T patent/DK2475788T3/da active
- 2010-08-31 DK DK18169040.5T patent/DK3375891T3/da active
- 2010-08-31 PT PT181690405T patent/PT3375891T/pt unknown
- 2010-08-31 DK DK18169032.2T patent/DK3375890T3/da active
- 2010-08-31 PT PT181690322T patent/PT3375890T/pt unknown
- 2010-08-31 US US13/394,944 patent/US9938569B2/en active Active
- 2010-08-31 EP EP18169040.5A patent/EP3375891B1/en active Active
- 2010-08-31 MX MX2012002902A patent/MX352971B/es active IP Right Grant
- 2010-08-31 ES ES10815913.8T patent/ES2680495T3/es active Active
-
2018
- 2018-03-12 US US15/918,369 patent/US11603559B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3375890B1 (en) | 2020-01-22 |
| EP2475788A1 (en) | 2012-07-18 |
| DK2475788T3 (da) | 2018-07-30 |
| EP3375890A1 (en) | 2018-09-19 |
| PT3375890T (pt) | 2020-04-23 |
| CN102482720A (zh) | 2012-05-30 |
| PT3375891T (pt) | 2020-05-11 |
| EP2475788A4 (en) | 2013-05-29 |
| MX352971B (es) | 2017-12-15 |
| US20180201987A1 (en) | 2018-07-19 |
| US9938569B2 (en) | 2018-04-10 |
| US20120171677A1 (en) | 2012-07-05 |
| ES2680495T3 (es) | 2018-09-07 |
| US11603559B2 (en) | 2023-03-14 |
| CN102482720B (zh) | 2014-10-08 |
| ES2785672T3 (es) | 2020-10-07 |
| EP3375891A1 (en) | 2018-09-19 |
| EP3375891B1 (en) | 2020-02-19 |
| ES2791369T3 (es) | 2020-11-04 |
| MX2012002902A (es) | 2012-04-02 |
| WO2011031585A1 (en) | 2011-03-17 |
| EP2475788B1 (en) | 2018-04-25 |
| DK3375891T3 (da) | 2020-04-27 |
| PT2475788T (pt) | 2018-07-24 |
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