DK3360863T3 - Etomidatderivat og mellemprodukt, fremgangsmåde til fremstilling og anvendelse deraf - Google Patents
Etomidatderivat og mellemprodukt, fremgangsmåde til fremstilling og anvendelse deraf Download PDFInfo
- Publication number
- DK3360863T3 DK3360863T3 DK16853130.9T DK16853130T DK3360863T3 DK 3360863 T3 DK3360863 T3 DK 3360863T3 DK 16853130 T DK16853130 T DK 16853130T DK 3360863 T3 DK3360863 T3 DK 3360863T3
- Authority
- DK
- Denmark
- Prior art keywords
- manufacture
- etomidate derivative
- etomidate
- derivative
- Prior art date
Links
- NPUKDXXFDDZOKR-LLVKDONJSA-N etomidate Chemical class CCOC(=O)C1=CN=CN1[C@H](C)C1=CC=CC=C1 NPUKDXXFDDZOKR-LLVKDONJSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510650913 | 2015-10-10 | ||
| PCT/CN2016/101696 WO2017059827A1 (zh) | 2015-10-10 | 2016-10-10 | 依托咪酯衍生物及其中间体、制备方法和用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3360863T3 true DK3360863T3 (da) | 2022-06-13 |
Family
ID=58487268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16853130.9T DK3360863T3 (da) | 2015-10-10 | 2016-10-10 | Etomidatderivat og mellemprodukt, fremgangsmåde til fremstilling og anvendelse deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10392352B2 (da) |
| EP (1) | EP3360863B1 (da) |
| JP (1) | JP6983416B2 (da) |
| CN (2) | CN113880770A (da) |
| CA (1) | CA3001431C (da) |
| DK (1) | DK3360863T3 (da) |
| ES (1) | ES2913090T3 (da) |
| HU (1) | HUE058909T2 (da) |
| PL (1) | PL3360863T3 (da) |
| WO (1) | WO2017059827A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109748876A (zh) * | 2017-11-02 | 2019-05-14 | 北京蓝丹医药科技有限公司 | 依托咪酯衍生物及其制备方法 |
| CN109776510B (zh) * | 2018-01-30 | 2023-08-18 | 成都麻沸散医药科技有限公司 | 一种n-取代咪唑甲酸酯类衍生物及其用途 |
| WO2021068943A1 (zh) * | 2019-10-11 | 2021-04-15 | 成都麻沸散医药科技有限公司 | 一种取代氮杂环化合物及其麻醉作用 |
| CN116262729A (zh) * | 2021-12-15 | 2023-06-16 | 燃点(南京)生物医药科技有限公司 | 一类依托咪酯杂质化合物、制备方法及其应用 |
| CN116265442B (zh) * | 2021-12-16 | 2024-08-06 | 燃点(南京)生物医药科技有限公司 | 一种依托咪酯的制备方法 |
| CN119462514B (zh) * | 2025-01-16 | 2025-03-14 | 四川大学华西医院 | 依托咪酯衍生物及其制备方法和在制备麻醉药物中的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009251659B2 (en) * | 2008-03-31 | 2013-07-11 | The General Hospital Corporation | Etomidate analogues with improved pharmacokinetic and pharmacodynamic properties |
| WO2011005969A2 (en) * | 2009-07-10 | 2011-01-13 | The General Hospital Corporation | Etomidate analogues that do not inhibit adrenocortical steroid synthesis |
| PL2802325T3 (pl) * | 2012-01-13 | 2017-11-30 | The General Hospital Corporation | Związki znieczulające i powiązane sposoby zastosowania |
| CN104706587A (zh) * | 2013-12-16 | 2015-06-17 | 天津迈迪瑞康生物医药科技有限公司 | 一种依托咪酯脂肪乳浓缩液、其制备方法及用途 |
| CN103739553B (zh) * | 2013-12-23 | 2014-11-12 | 四川大学华西医院 | 含有醚侧链的n-取代咪唑羧酸酯手性化合物、制备方法和用途 |
-
2016
- 2016-10-10 WO PCT/CN2016/101696 patent/WO2017059827A1/zh not_active Ceased
- 2016-10-10 HU HUE16853130A patent/HUE058909T2/hu unknown
- 2016-10-10 ES ES16853130T patent/ES2913090T3/es active Active
- 2016-10-10 CN CN202111196263.0A patent/CN113880770A/zh active Pending
- 2016-10-10 CA CA3001431A patent/CA3001431C/en active Active
- 2016-10-10 DK DK16853130.9T patent/DK3360863T3/da active
- 2016-10-10 CN CN201680059075.4A patent/CN108349906B/zh active Active
- 2016-10-10 EP EP16853130.9A patent/EP3360863B1/en active Active
- 2016-10-10 US US15/767,009 patent/US10392352B2/en active Active
- 2016-10-10 JP JP2018537709A patent/JP6983416B2/ja active Active
- 2016-10-10 PL PL16853130.9T patent/PL3360863T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6983416B2 (ja) | 2021-12-17 |
| EP3360863A4 (en) | 2019-06-19 |
| ES2913090T3 (es) | 2022-05-31 |
| WO2017059827A1 (zh) | 2017-04-13 |
| PL3360863T3 (pl) | 2022-08-08 |
| US10392352B2 (en) | 2019-08-27 |
| HUE058909T2 (hu) | 2022-09-28 |
| CA3001431C (en) | 2023-09-26 |
| US20180297958A1 (en) | 2018-10-18 |
| CN108349906B (zh) | 2021-11-02 |
| CA3001431A1 (en) | 2017-04-13 |
| CN108349906A (zh) | 2018-07-31 |
| EP3360863B1 (en) | 2022-04-20 |
| JP2018530611A (ja) | 2018-10-18 |
| EP3360863A1 (en) | 2018-08-15 |
| CN113880770A (zh) | 2022-01-04 |
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