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DK3203999T3 - Substituerede aromatiske forbindelser og farmaceutiske sammensætninger til forebyggelse og behandling af osteoporose - Google Patents

Substituerede aromatiske forbindelser og farmaceutiske sammensætninger til forebyggelse og behandling af osteoporose Download PDF

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Publication number
DK3203999T3
DK3203999T3 DK15849675.2T DK15849675T DK3203999T3 DK 3203999 T3 DK3203999 T3 DK 3203999T3 DK 15849675 T DK15849675 T DK 15849675T DK 3203999 T3 DK3203999 T3 DK 3203999T3
Authority
DK
Denmark
Prior art keywords
osteoporosis
prevention
treatment
pharmaceutical compositions
aromatic compounds
Prior art date
Application number
DK15849675.2T
Other languages
English (en)
Inventor
Lyne Gagnon
Brigitte Grouix
Original Assignee
Liminal Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liminal Biosciences Ltd filed Critical Liminal Biosciences Ltd
Application granted granted Critical
Publication of DK3203999T3 publication Critical patent/DK3203999T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/32Phenylacetic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK15849675.2T 2014-10-10 2015-10-08 Substituerede aromatiske forbindelser og farmaceutiske sammensætninger til forebyggelse og behandling af osteoporose DK3203999T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462062597P 2014-10-10 2014-10-10
PCT/CA2015/000540 WO2016054728A1 (en) 2014-10-10 2015-10-08 Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis

Publications (1)

Publication Number Publication Date
DK3203999T3 true DK3203999T3 (da) 2020-03-30

Family

ID=55652429

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15849675.2T DK3203999T3 (da) 2014-10-10 2015-10-08 Substituerede aromatiske forbindelser og farmaceutiske sammensætninger til forebyggelse og behandling af osteoporose

Country Status (23)

Country Link
US (2) US20180228750A1 (da)
EP (1) EP3203999B1 (da)
JP (1) JP6700639B2 (da)
KR (1) KR20170066476A (da)
CN (1) CN106999456B (da)
AR (1) AR102246A1 (da)
AU (1) AU2015330645B2 (da)
BR (1) BR112017007426A2 (da)
CA (1) CA2963354A1 (da)
DK (1) DK3203999T3 (da)
ES (1) ES2785317T3 (da)
IL (1) IL251404B (da)
MX (1) MX376873B (da)
MY (1) MY194308A (da)
PH (1) PH12017500638A1 (da)
PL (1) PL3203999T3 (da)
PT (1) PT3203999T (da)
RU (1) RU2709205C2 (da)
SG (1) SG11201702868VA (da)
TW (1) TWI699200B (da)
UY (1) UY36356A (da)
WO (1) WO2016054728A1 (da)
ZA (1) ZA201702639B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2794782T3 (es) * 2014-10-10 2020-11-19 Liminal Biosciences Ltd Compuestos de carboxilato de fenilcetona y composiciones farmacéuticas para la prevención y el tratamiento de la osteoporosis
US10391073B2 (en) * 2014-11-12 2019-08-27 Prometic Pharma Smt Limited Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration
BR112017019170A2 (pt) 2015-03-09 2018-07-10 Intekrin Therapeutics, Inc. métodos para o tratamento de doença do fígado gorduroso não alcoólico e / ou lipodistrofia
SG10202101500WA (en) * 2016-08-18 2021-03-30 Intekrin Therapeutics Inc PPARγ AGONIST FOR TREATMENT OF BONE DISORDERS
US11253508B2 (en) 2017-04-03 2022-02-22 Coherus Biosciences, Inc. PPARy agonist for treatment of progressive supranuclear palsy
JP2024512510A (ja) * 2020-10-06 2024-03-19 ファーマセウティーク・インジェニュー・インコーポレイテッド 置換芳香族化合物及びその医薬組成物
AU2022392186A1 (en) * 2021-11-17 2024-06-06 Natreon, Inc. Withania somnifera and asparagus racemosus in treating post-menopausal conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006124662A1 (en) * 2005-05-13 2006-11-23 Synta Pharmaceuticals Corp. Il-12 modulatory compounds
KR20120024696A (ko) * 2009-05-04 2012-03-14 프로메틱 바이오사이언시즈 인코포레이티드 치환된 방향족 화합물 및 그의 약학적 용도
AU2010244938A1 (en) * 2009-05-04 2011-11-17 Prometic Pharma Smt Limited Salts of 3-pentylphenylacetic acid and pharmaceutical uses thereof
EA030038B1 (ru) * 2010-10-27 2018-06-29 Прометик Фарма Смт Лимитед Применение соединений для лечения рака и способ лечения рака
PH12013500763B1 (en) * 2010-10-27 2018-07-04 Prometic Pharma Smt Ltd Phenylketone carboxylate compounds and pharmaceutical uses thereof
TWI689490B (zh) * 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療纖維化之經取代之芳族化合物及相關方法
TWI742541B (zh) * 2013-03-15 2021-10-11 英商邊緣生物科技有限公司 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物
ES2794782T3 (es) * 2014-10-10 2020-11-19 Liminal Biosciences Ltd Compuestos de carboxilato de fenilcetona y composiciones farmacéuticas para la prevención y el tratamiento de la osteoporosis

Also Published As

Publication number Publication date
KR20170066476A (ko) 2017-06-14
CA2963354A1 (en) 2016-04-14
PH12017500638A1 (en) 2017-09-25
RU2709205C2 (ru) 2019-12-17
ZA201702639B (en) 2018-06-27
UY36356A (es) 2016-06-01
US11185521B2 (en) 2021-11-30
AU2015330645A1 (en) 2017-05-04
RU2017116178A3 (da) 2019-05-16
US20180228750A1 (en) 2018-08-16
ES2785317T3 (es) 2020-10-06
EP3203999B1 (en) 2020-01-08
JP6700639B2 (ja) 2020-05-27
RU2017116178A (ru) 2018-11-19
IL251404B (en) 2020-11-30
EP3203999A1 (en) 2017-08-16
PT3203999T (pt) 2020-04-23
US20200237693A1 (en) 2020-07-30
EP3203999A4 (en) 2018-06-27
MX376873B (es) 2025-03-07
MX2017004733A (es) 2017-07-17
SG11201702868VA (en) 2017-05-30
MY194308A (en) 2022-11-27
TWI699200B (zh) 2020-07-21
CN106999456A (zh) 2017-08-01
WO2016054728A1 (en) 2016-04-14
TW201618762A (zh) 2016-06-01
CN106999456B (zh) 2020-07-10
AR102246A1 (es) 2017-02-15
JP2017530180A (ja) 2017-10-12
AU2015330645B2 (en) 2020-03-12
PL3203999T3 (pl) 2020-07-27
BR112017007426A2 (pt) 2018-01-16
IL251404A0 (en) 2017-05-29

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