DK3276004T3 - Fremgangsmåder til behandling af kronisk nyresygdom - Google Patents
Fremgangsmåder til behandling af kronisk nyresygdom Download PDFInfo
- Publication number
- DK3276004T3 DK3276004T3 DK17190227.3T DK17190227T DK3276004T3 DK 3276004 T3 DK3276004 T3 DK 3276004T3 DK 17190227 T DK17190227 T DK 17190227T DK 3276004 T3 DK3276004 T3 DK 3276004T3
- Authority
- DK
- Denmark
- Prior art keywords
- nonus
- procedures
- disease
- treating chronic
- chronic
- Prior art date
Links
- 230000001684 chronic effect Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 0 C(C1)*C1C1[C@]2CC*1C2 Chemical compound C(C1)*C1C1[C@]2CC*1C2 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/343—Spatial arrangement of the modifications having patterns, e.g. ==--==--==--
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18493709P | 2009-06-08 | 2009-06-08 | |
| US23538109P | 2009-08-20 | 2009-08-20 | |
| EP10786615.4A EP2440214A4 (en) | 2009-06-08 | 2010-06-07 | METHOD FOR THE TREATMENT OF CHRONIC KIDNEY DISEASES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3276004T3 true DK3276004T3 (da) | 2020-04-06 |
Family
ID=43309421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17190227.3T DK3276004T3 (da) | 2009-06-08 | 2010-06-07 | Fremgangsmåder til behandling af kronisk nyresygdom |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8637482B2 (da) |
| EP (2) | EP3276004B1 (da) |
| JP (1) | JP2012529430A (da) |
| CN (1) | CN102458418B (da) |
| CA (1) | CA2763537A1 (da) |
| DK (1) | DK3276004T3 (da) |
| IL (1) | IL216804A0 (da) |
| WO (1) | WO2010144336A2 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6132775B2 (ja) | 2011-03-03 | 2017-05-24 | クォーク ファーマシューティカルズ インコーポレーティッドＱｕａｒｋ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | Ｔｏｌｌ様受容体経路のオリゴヌクレオチド修飾因子 |
| US9796979B2 (en) | 2011-03-03 | 2017-10-24 | Quark Pharmaceuticals Inc. | Oligonucleotide modulators of the toll-like receptor pathway |
| US9631170B2 (en) | 2011-10-06 | 2017-04-25 | University Of Wyoming | Genetically inducible hydrogen peroxide resistance and production |
| DK2895608T3 (da) | 2012-09-12 | 2019-01-21 | Quark Pharmaceuticals Inc | Dobbeltstrengede oligonukleotidmolekyler til p53 og fremgangsmåder til anvendelse deraf |
| ES2872349T3 (es) | 2012-09-12 | 2021-11-02 | Quark Pharmaceuticals Inc | Moléculas de oligonucleótidos bicatenarios para DDIT4 y métodos de uso de las mismas |
| US9546364B2 (en) | 2013-03-15 | 2017-01-17 | Carnegie Mellon University | Synthetic lariat RNA for RNA interference |
| CN104073517A (zh) * | 2013-03-28 | 2014-10-01 | 卫生部北京医院 | p66Shc重组腺病毒载体及构建和应用 |
| AU2014265669B2 (en) * | 2013-05-14 | 2020-05-14 | Metabolon, Inc. | Biomarkers related to kidney function and methods using the same |
| CN112410336A (zh) * | 2014-05-29 | 2021-02-26 | 夸克制药公司 | 用于预防器官中缺血再灌注损伤的方法和组合物 |
| GB201413081D0 (en) * | 2014-07-23 | 2014-09-03 | Univ Birmingham | Markers for AF |
| ES2627997B1 (es) * | 2015-09-18 | 2018-05-21 | Fundación Instituto De Investigación Sanitaria Fundación Jiménez Díaz | Uso de una composición farmacéutica para la fabricación de un medicamento para el tratamiento y/o la prevención del daño renal agudo |
| EP4442200A3 (en) * | 2016-04-01 | 2024-12-04 | Cardiac Pacemakers, Inc. | Multi-disease patient management |
| WO2018027149A1 (en) * | 2016-08-04 | 2018-02-08 | University Of Miami | Methods of treating alport syndrome |
| EP3548005A4 (en) | 2016-11-29 | 2020-06-17 | Puretech Health LLC | Exosomes for delivery of therapeutic agents |
| PL3631472T3 (pl) | 2017-05-31 | 2022-10-17 | Mars, Incorporated | Sposoby diagnozowania i leczenia przewlekłej choroby nerek |
| CN116726173B (zh) * | 2022-03-03 | 2025-09-23 | 浙江大学 | Trpm2抑制剂的用途 |
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| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| US4925678A (en) | 1987-04-01 | 1990-05-15 | Ranney David F | Endothelial envelopment drug carriers |
| US5080646A (en) | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5167616A (en) | 1989-12-14 | 1992-12-01 | Alza Corporation | Iontophoretic delivery method |
| US5225182A (en) | 1991-10-31 | 1993-07-06 | Sharma Yash P | Vectored drug delivery system using a cephaloplastin linking agent and a methed of using the system |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| US5998203A (en) | 1996-04-16 | 1999-12-07 | Ribozyme Pharmaceuticals, Inc. | Enzymatic nucleic acids containing 5'-and/or 3'-cap structures |
| US20050032067A1 (en) | 2002-11-05 | 2005-02-10 | Prakash Thazha P. | Non-phosphorous-linked oligomeric compounds and their use in gene modulation |
| US5898031A (en) | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| US20050042647A1 (en) | 1996-06-06 | 2005-02-24 | Baker Brenda F. | Phosphorous-linked oligomeric compounds and their use in gene modulation |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US6251666B1 (en) | 1997-03-31 | 2001-06-26 | Ribozyme Pharmaceuticals, Inc. | Nucleic acid catalysts comprising L-nucleotide analogs |
| WO1999014226A2 (en) | 1997-09-12 | 1999-03-25 | Exiqon A/S | Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues |
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| US6693187B1 (en) | 2000-10-17 | 2004-02-17 | Lievre Cornu Llc | Phosphinoamidite carboxlates and analogs thereof in the synthesis of oligonucleotides having reduced internucleotide charge |
| TR200401292T3 (tr) | 2000-12-01 | 2004-07-21 | Max@Planck@Gesellschaft�Zur�F�Rderung�Der�Wissenschaften | RNAÁgirişimineÁyolÁaçanÁküçükÁRNAÁmolekülleri |
| KR20100087400A (ko) | 2001-11-21 | 2010-08-04 | 가오루 사이고 | 유전자 발현 억제 방법 |
| PT1527176E (pt) | 2002-08-05 | 2007-04-30 | Atugen Ag | Novas formas de muléculas de arn de interferência |
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| ATE443765T1 (de) | 2003-03-21 | 2009-10-15 | Santaris Pharma As | Analoga kurzer interferierender rna (sirna) |
| PT1799269T (pt) * | 2004-09-28 | 2016-10-04 | Quark Pharmaceuticals Inc | Oligorribonucleótidos e métodos para uso dos mesmos para o tratamento da alopecia, insuficiência renal aguda e outras doenças |
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| DOP2007000015A (es) * | 2006-01-20 | 2007-08-31 | Quark Biotech Inc | Usos terapéuticos de inhibidores de rtp801 |
| EP1989307B1 (en) | 2006-02-08 | 2012-08-08 | Quark Pharmaceuticals, Inc. | NOVEL TANDEM siRNAS |
| US7910566B2 (en) | 2006-03-09 | 2011-03-22 | Quark Pharmaceuticals Inc. | Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA |
| US20080090765A1 (en) | 2006-05-25 | 2008-04-17 | The Trustees Of Columbia University In The City Of New York | Compositions for modulating growth of embryonic and adult kidney tissue and uses for treating kidney damage |
| CA2665365A1 (en) * | 2006-10-05 | 2008-04-10 | Rhode Island Hospital | Compositions and methods for detecting and treating renal injury and inflammation |
| JP2010507387A (ja) | 2006-10-25 | 2010-03-11 | クアーク・ファーマスーティカルス、インコーポレイテッド | 新規のｓｉＲＮＡおよびその使用方法 |
| EP2137205A2 (en) * | 2007-02-26 | 2009-12-30 | Quark Pharmaceuticals, Inc. | Inhibitors of rtp801 and their use in disease treatment |
| WO2008104978A2 (en) | 2007-02-28 | 2008-09-04 | Quark Pharmaceuticals, Inc. | Novel sirna structures |
| WO2009001359A2 (en) | 2007-06-27 | 2008-12-31 | Quark Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of pro-apoptotic genes |
| WO2009032915A2 (en) | 2007-09-06 | 2009-03-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Arrays, kits and cancer characterization methods |
| CN103898110A (zh) * | 2007-10-03 | 2014-07-02 | 夸克制药公司 | 新siRNA结构 |
| US20090226547A1 (en) | 2008-03-05 | 2009-09-10 | Gilbard Jeffrey P | Dietary Supplement For Eye Health |
| KR20100132531A (ko) * | 2008-03-20 | 2010-12-17 | 쿠아크 파마수티칼스 인코퍼레이티드 | ＲＴＰ801을 억제하기 위한 신규 ｓｉＲＮＡ 화합물 |
-
2010
- 2010-06-07 DK DK17190227.3T patent/DK3276004T3/da active
- 2010-06-07 EP EP17190227.3A patent/EP3276004B1/en active Active
- 2010-06-07 CA CA2763537A patent/CA2763537A1/en not_active Abandoned
- 2010-06-07 JP JP2012514218A patent/JP2012529430A/ja active Pending
- 2010-06-07 CN CN201080028245.5A patent/CN102458418B/zh not_active Expired - Fee Related
- 2010-06-07 WO PCT/US2010/037565 patent/WO2010144336A2/en not_active Ceased
- 2010-06-07 US US13/376,766 patent/US8637482B2/en active Active
- 2010-06-07 EP EP10786615.4A patent/EP2440214A4/en not_active Withdrawn
-
2011
- 2011-12-06 IL IL216804A patent/IL216804A0/en unknown
-
2014
- 2014-01-27 US US14/165,249 patent/US20140140922A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010144336A3 (en) | 2011-02-03 |
| EP2440214A4 (en) | 2013-07-31 |
| IL216804A0 (en) | 2012-02-29 |
| CA2763537A1 (en) | 2010-12-16 |
| EP2440214A2 (en) | 2012-04-18 |
| US20140140922A1 (en) | 2014-05-22 |
| JP2012529430A (ja) | 2012-11-22 |
| WO2010144336A2 (en) | 2010-12-16 |
| CN102458418B (zh) | 2015-09-16 |
| CN102458418A (zh) | 2012-05-16 |
| US20120141378A1 (en) | 2012-06-07 |
| EP3276004A3 (en) | 2018-03-14 |
| EP3276004B1 (en) | 2020-03-18 |
| US8637482B2 (en) | 2014-01-28 |
| EP3276004A2 (en) | 2018-01-31 |
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