DK3271389T3 - Neutraliserende antistoffer mod gp120 og anvendelse deraf - Google Patents
Neutraliserende antistoffer mod gp120 og anvendelse deraf Download PDFInfo
- Publication number
- DK3271389T3 DK3271389T3 DK16716979.6T DK16716979T DK3271389T3 DK 3271389 T3 DK3271389 T3 DK 3271389T3 DK 16716979 T DK16716979 T DK 16716979T DK 3271389 T3 DK3271389 T3 DK 3271389T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies against
- neutralizing antibodies
- neutralizing
- antibodies
- Prior art date
Links
- 230000003472 neutralizing effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- G01N2333/162—HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562136228P | 2015-03-20 | 2015-03-20 | |
| US201562250378P | 2015-11-03 | 2015-11-03 | |
| PCT/US2016/023145 WO2016154003A1 (en) | 2015-03-20 | 2016-03-18 | Neutralizing antibodies to gp120 and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3271389T3 true DK3271389T3 (da) | 2020-04-27 |
Family
ID=55755690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16716979.6T DK3271389T3 (da) | 2015-03-20 | 2016-03-18 | Neutraliserende antistoffer mod gp120 og anvendelse deraf |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US10562960B2 (da) |
| EP (2) | EP3271389B8 (da) |
| CN (1) | CN108137676B (da) |
| AU (1) | AU2016235541B2 (da) |
| CA (1) | CA2980005A1 (da) |
| CY (1) | CY1123068T1 (da) |
| DK (1) | DK3271389T3 (da) |
| ES (1) | ES2789348T3 (da) |
| HR (1) | HRP20200583T1 (da) |
| HU (1) | HUE049081T2 (da) |
| LT (1) | LT3271389T (da) |
| PL (1) | PL3271389T3 (da) |
| PT (1) | PT3271389T (da) |
| RS (1) | RS60270B1 (da) |
| SI (1) | SI3271389T1 (da) |
| SM (1) | SMT202000255T1 (da) |
| WO (1) | WO2016154003A1 (da) |
| ZA (1) | ZA201706155B (da) |
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| ES2789348T3 (es) | 2015-03-20 | 2020-10-26 | Us Health | Anticuerpos neutralizantes para GP120 y sus usos |
| WO2018075989A1 (en) | 2016-10-21 | 2018-04-26 | Altor Bioscience Corporation | Multimeric il-15-based molecules |
| US10882907B2 (en) * | 2017-06-21 | 2021-01-05 | Gilead Sciences, Inc. | Multispecific antibodies that target HIV GP120 and CD3 |
| US20200172601A1 (en) | 2017-06-22 | 2020-06-04 | University Of Maryland, Baltimore | Broadly neutralizing antibodies against hiv |
| CN107098969B (zh) * | 2017-06-28 | 2018-10-12 | 武汉波睿达生物科技有限公司 | 一种治疗hiv感染的嵌合抗原受体的重组基因构建及其应用 |
| CA3091437A1 (en) | 2018-02-21 | 2019-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to hiv-1 env and their use |
| WO2019173794A1 (en) * | 2018-03-09 | 2019-09-12 | Atreca, Inc. | Anti-hiv antibodies |
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| CN109251246B (zh) * | 2018-09-14 | 2022-01-28 | 南开大学 | Hiv-1广谱中和抗体及其用途 |
| WO2020086446A1 (en) * | 2018-10-22 | 2020-04-30 | International Aids Vaccine Initiative | Anti-hiv antibodies |
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- 2016-03-18 ES ES16716979T patent/ES2789348T3/es active Active
- 2016-03-18 CN CN201680028822.8A patent/CN108137676B/zh active Active
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- 2016-03-18 SM SM20200255T patent/SMT202000255T1/it unknown
- 2016-03-18 DK DK16716979.6T patent/DK3271389T3/da active
- 2016-03-18 LT LTEP16716979.6T patent/LT3271389T/lt unknown
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- 2016-03-18 RS RS20200525A patent/RS60270B1/sr unknown
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- 2016-03-18 HU HUE16716979A patent/HUE049081T2/hu unknown
- 2016-03-18 WO PCT/US2016/023145 patent/WO2016154003A1/en not_active Ceased
- 2016-03-18 CA CA2980005A patent/CA2980005A1/en active Pending
- 2016-03-18 SI SI201630711T patent/SI3271389T1/sl unknown
- 2016-03-18 US US15/559,791 patent/US10562960B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| LT3271389T (lt) | 2020-05-25 |
| WO2016154003A1 (en) | 2016-09-29 |
| HRP20200583T1 (hr) | 2020-07-10 |
| US20200231658A1 (en) | 2020-07-23 |
| US20230060304A1 (en) | 2023-03-02 |
| PL3271389T3 (pl) | 2020-08-10 |
| CA2980005A1 (en) | 2016-09-29 |
| HUE049081T2 (hu) | 2020-09-28 |
| ZA201706155B (en) | 2022-05-25 |
| PT3271389T (pt) | 2020-05-13 |
| US10562960B2 (en) | 2020-02-18 |
| CN108137676B (zh) | 2022-03-15 |
| CN108137676A (zh) | 2018-06-08 |
| SMT202000255T1 (it) | 2020-07-08 |
| EP3271389B1 (en) | 2020-02-12 |
| US12202886B2 (en) | 2025-01-21 |
| SI3271389T1 (sl) | 2020-09-30 |
| RS60270B1 (sr) | 2020-06-30 |
| EP3271389A1 (en) | 2018-01-24 |
| US20210324053A1 (en) | 2021-10-21 |
| EP3271389B8 (en) | 2020-04-22 |
| US20250215068A1 (en) | 2025-07-03 |
| EP3683233A1 (en) | 2020-07-22 |
| WO2016154003A8 (en) | 2016-10-27 |
| ES2789348T3 (es) | 2020-10-26 |
| US20180298083A1 (en) | 2018-10-18 |
| AU2016235541B2 (en) | 2021-04-01 |
| EP4620530A2 (en) | 2025-09-24 |
| AU2016235541A1 (en) | 2017-09-28 |
| US20250179154A1 (en) | 2025-06-05 |
| CY1123068T1 (el) | 2020-11-25 |
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