DK3251678T3 - Benzoxaborolderivater til behandling af bakterieinfektioner - Google Patents
Benzoxaborolderivater til behandling af bakterieinfektioner Download PDFInfo
- Publication number
- DK3251678T3 DK3251678T3 DK17176654.6T DK17176654T DK3251678T3 DK 3251678 T3 DK3251678 T3 DK 3251678T3 DK 17176654 T DK17176654 T DK 17176654T DK 3251678 T3 DK3251678 T3 DK 3251678T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzoxaborol
- derivatives
- treatment
- bacteria infections
- infections
- Prior art date
Links
- GDMJXXLVTYSBBE-UHFFFAOYSA-N 1,2-benzoxaborole Chemical class C1=CC=C2OB=CC2=C1 GDMJXXLVTYSBBE-UHFFFAOYSA-N 0.000 title 1
- 241000894006 Bacteria Species 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38059610P | 2010-09-07 | 2010-09-07 | |
| EP11758050.6A EP2613788B1 (en) | 2010-09-07 | 2011-09-07 | Benzoxaborole derivatives for treating bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3251678T3 true DK3251678T3 (da) | 2021-11-22 |
Family
ID=44653589
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11758050.6T DK2613788T3 (da) | 2010-09-07 | 2011-09-07 | Benzoxaborolderivater til behandling af bakterieinfektioner |
| DK17176654.6T DK3251678T3 (da) | 2010-09-07 | 2011-09-07 | Benzoxaborolderivater til behandling af bakterieinfektioner |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11758050.6T DK2613788T3 (da) | 2010-09-07 | 2011-09-07 | Benzoxaborolderivater til behandling af bakterieinfektioner |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US8703742B2 (da) |
| EP (2) | EP3251678B1 (da) |
| JP (4) | JP5952280B2 (da) |
| KR (2) | KR101949423B1 (da) |
| CN (2) | CN103140228A (da) |
| AU (1) | AU2011299243C1 (da) |
| BR (1) | BR112013005426B1 (da) |
| CA (1) | CA2810021C (da) |
| CY (1) | CY1124728T1 (da) |
| DK (2) | DK2613788T3 (da) |
| EA (2) | EA028743B1 (da) |
| ES (2) | ES2635333T3 (da) |
| HR (1) | HRP20211762T1 (da) |
| HU (1) | HUE059033T2 (da) |
| IL (2) | IL225000A (da) |
| LT (1) | LT3251678T (da) |
| MX (1) | MX338209B (da) |
| PL (1) | PL3251678T3 (da) |
| PT (1) | PT3251678T (da) |
| RS (1) | RS62548B1 (da) |
| SG (2) | SG10201507032YA (da) |
| SI (1) | SI3251678T1 (da) |
| SM (1) | SMT202100643T1 (da) |
| WO (1) | WO2012033858A2 (da) |
| ZA (1) | ZA201301598B (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2635680A1 (en) | 2005-12-30 | 2007-07-12 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| AP4039A (en) | 2009-08-14 | 2017-02-28 | Daitao Chen | Boron-containing small molecules as antiprotozoal agents |
| US8716478B2 (en) | 2010-01-27 | 2014-05-06 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| PL3251678T3 (pl) * | 2010-09-07 | 2022-01-10 | Anacor Pharmaceuticals, Inc. | Pochodne benzoksaborolu do leczenia zakażeń bakteryjnych |
| WO2013093615A1 (en) | 2011-12-22 | 2013-06-27 | Micurx Pharmaceuticals, Inc. | Tricyclic boron compounds for antimicrobial therapy |
| US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
| KR101666331B1 (ko) | 2013-01-30 | 2016-10-13 | 다우 아그로사이언시즈 엘엘씨 | 육류, 식물, 또는 식물 부분에 대한 휘발성 항미생물제로서의 벤족사보롤의 용도 |
| US8669207B1 (en) | 2013-01-30 | 2014-03-11 | Dow Agrosciences, Llc. | Compounds and compositions |
| US9585396B2 (en) | 2013-01-30 | 2017-03-07 | Agrofresh Inc. | Volatile applications against pathogens |
| US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
| WO2014121124A1 (en) | 2013-02-01 | 2014-08-07 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| KR101636431B1 (ko) | 2013-07-30 | 2016-07-05 | 동아에스티 주식회사 | 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도 |
| SI3030519T1 (sl) * | 2013-08-09 | 2022-04-29 | Glaxosmithkline Intellectual Property (No.2) Limited | Triciklične benzoksaborolne spojine in njihove uporabe |
| EA038093B1 (ru) * | 2013-12-20 | 2021-07-05 | Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед | Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли |
| TW201625649A (zh) | 2014-07-01 | 2016-07-16 | 第一三共股份有限公司 | 作爲抗菌劑的三環化合物 |
| MA41494B1 (fr) * | 2015-02-12 | 2020-10-28 | Glaxosmithkline Ip No 2 Ltd | Composés benzoxaborole substitués en position 4 et utilisations associées |
| WO2017155879A1 (en) | 2016-03-07 | 2017-09-14 | Agrofresh Inc. | Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops |
| EP3609504A4 (en) | 2017-03-01 | 2021-03-03 | Anacor Pharmaceuticals, Inc. | NEW OXABOROLE ANALOGUES AND USES OF THE LATEST |
| US11834466B2 (en) | 2017-11-30 | 2023-12-05 | 5Metis, Inc. | Benzoxaborole compounds and formulations thereof |
| CN108727176B (zh) * | 2018-07-26 | 2021-05-18 | 荆楚理工学院 | 一种制备5-卤-2,3-二羟基苯甲醛的方法 |
| JP2021534247A (ja) | 2018-08-18 | 2021-12-09 | ボラゲン,インコーポレーテッド | 置換ベンゾキサボロールの固体形態およびその組成物 |
| US20220275007A1 (en) * | 2019-07-30 | 2022-09-01 | Boragen, Inc. | Flow reaction process for manufacture of boron-containing agrochemicals |
| CN110664756B (zh) * | 2019-10-09 | 2020-11-17 | 吉林大学 | 一种小儿外伤喷雾剂及其制备方法 |
| US20230340530A1 (en) | 2020-08-31 | 2023-10-26 | Pfizer Inc. | Methods of Protecting RNA |
| WO2023246841A1 (en) * | 2022-06-23 | 2023-12-28 | Shanghai Micurx Pharmaceutical Co., Ltd. | Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same |
| CN119233977A (zh) * | 2022-06-23 | 2024-12-31 | 上海盟科药业股份有限公司 | 硼化合物的前药及其在治疗细菌感染中的用途 |
| CN115572218B (zh) * | 2022-08-29 | 2024-04-16 | 江阴勒森生物科技有限公司 | 一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法 |
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-
2011
- 2011-09-07 PL PL17176654T patent/PL3251678T3/pl unknown
- 2011-09-07 MX MX2013002651A patent/MX338209B/es active IP Right Grant
- 2011-09-07 SG SG10201507032YA patent/SG10201507032YA/en unknown
- 2011-09-07 KR KR1020137005717A patent/KR101949423B1/ko active Active
- 2011-09-07 CN CN2011800427618A patent/CN103140228A/zh active Pending
- 2011-09-07 LT LTEP17176654.6T patent/LT3251678T/lt unknown
- 2011-09-07 KR KR1020197003860A patent/KR102152901B1/ko active Active
- 2011-09-07 US US13/227,444 patent/US8703742B2/en active Active
- 2011-09-07 PT PT171766546T patent/PT3251678T/pt unknown
- 2011-09-07 WO PCT/US2011/050728 patent/WO2012033858A2/en not_active Ceased
- 2011-09-07 EP EP17176654.6A patent/EP3251678B1/en active Active
- 2011-09-07 JP JP2013527375A patent/JP5952280B2/ja active Active
- 2011-09-07 SM SM20210643T patent/SMT202100643T1/it unknown
- 2011-09-07 EA EA201390274A patent/EA028743B1/ru not_active IP Right Cessation
- 2011-09-07 CN CN201810051113.2A patent/CN108610356B/zh active Active
- 2011-09-07 HU HUE17176654A patent/HUE059033T2/hu unknown
- 2011-09-07 DK DK11758050.6T patent/DK2613788T3/da active
- 2011-09-07 ES ES11758050.6T patent/ES2635333T3/es active Active
- 2011-09-07 EA EA201791850A patent/EA033311B1/ru unknown
- 2011-09-07 BR BR112013005426-3A patent/BR112013005426B1/pt active IP Right Grant
- 2011-09-07 HR HRP20211762TT patent/HRP20211762T1/hr unknown
- 2011-09-07 SG SG2013014493A patent/SG187969A1/en unknown
- 2011-09-07 SI SI201132017T patent/SI3251678T1/sl unknown
- 2011-09-07 AU AU2011299243A patent/AU2011299243C1/en active Active
- 2011-09-07 CA CA2810021A patent/CA2810021C/en active Active
- 2011-09-07 EP EP11758050.6A patent/EP2613788B1/en active Active
- 2011-09-07 DK DK17176654.6T patent/DK3251678T3/da active
- 2011-09-07 RS RS20211391A patent/RS62548B1/sr unknown
- 2011-09-07 ES ES17176654T patent/ES2898695T3/es active Active
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2013
- 2013-02-28 IL IL225000A patent/IL225000A/en active IP Right Grant
- 2013-03-01 ZA ZA2013/01598A patent/ZA201301598B/en unknown
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2014
- 2014-03-21 US US14/221,637 patent/US9751898B2/en active Active
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2016
- 2016-03-13 IL IL244556A patent/IL244556B/en active IP Right Grant
- 2016-06-09 JP JP2016114971A patent/JP2016199558A/ja not_active Withdrawn
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2017
- 2017-08-24 US US15/685,846 patent/US20170355719A1/en not_active Abandoned
- 2017-10-06 JP JP2017195759A patent/JP6491294B2/ja active Active
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2019
- 2019-02-28 JP JP2019035145A patent/JP2019112431A/ja active Pending
- 2019-07-30 US US16/526,248 patent/US11008345B2/en active Active
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2021
- 2021-11-16 CY CY20211100990T patent/CY1124728T1/el unknown
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